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The map label for this gene is codB [C]

Identifier: 66043812

GI number: 66043812

Start: 617494

End: 618783

Strand: Direct

Name: codB [C]

Synonym: Psyr_0545

Alternate gene names: 66043812

Gene position: 617494-618783 (Clockwise)

Preceding gene: 66043811

Following gene: 66043814

Centisome position: 10.13

GC content: 63.33

Gene sequence:

>1290_bases
GTGAATACACCCGGCACCTATTCTCCCGATACCCCAGTCCCCGCCAGCCAGCGTGTGTTCGGCGGGCGGGATCTGTTTTC
ACTGTGGTTTTCCCTCGGCATCGGCTTGATGGTGTTGCAGACCGGTGCCTTGCTGGCGCCGGGGCTGGGCATGTCCGGCT
CGATGCTGGCAATTTTCCTCGGCACGCTGGCGGGCGTCTTGCTGCTCGCCAGCGTTGGCGTGATCGGCAGCGATACCGGC
CTGTCGTCCATGGCCGCGCTCAAGCTCAGCCTGGGTAGCAAGGGCGCGTCGCTGCCAGCGGTCTTGAACCTGCTGCAACT
GATCGGTTGGGGGGCGTTCGAGATCATCGTCATGCGCGACGCAGCCAGTCTGCTCGGCGCTCGGGCCTTTGCAGAGGGCA
GCCTGTGGAGCAGTCCGCTGCTCTGGACGCTGCTTTTCGGCGCACTGGCCACGTTGCTGGCGGTCAGCGGACCCTTGACC
TTCGTGCGCCGGTTTCTGCGCAAGTGGGGCCTGTGGATACTCTTGACGGCGTGTGCATGGCTGACCTGGAACCTGCTGGC
CAAGGCTGATCTGACCGCGCTGTGGGCAACCTCCGGCGATGGCTCGCTGCCGTTTGCCTCGGGGTTCGACATTGCCATCG
CCATGCCACTGTCGTGGCTGCCGCTGATTGCCGACTACTCACGCTTCGGGCAACGCGCGAAAAGTGTCTTCGGCGGCACG
GCTGCGGGCTTTTTCATCGGCAACTTCTGGCTGATGAGCCTGGGCGTCGCCTACACCCTGGCGTTCGCCCCGAGCGGCGA
GGTCAATGCCTTGCTGCTGGCACTGGCCGGCGCAGGTCTGGGTATCCCGCTGCTCCTGATTCTGCTGGACGAGACGGAAA
ATGCGTTCGCCGATATTCACTCGGCTGCAGTCTCCAGTGCTCTGTTGTCACGCATCAAGGTCGAGCATCTGGCGTTGGTG
ATTGGCGTGATCTGTACGCTGATCGCCTGTCTGGCACCGCTGGCGCAGTATCAGAACTTTCTGTTATTGATCGGCTCGGT
ATTCGCGCCACTGTTCGGCGTCGTGCTGGTTGACCATTTCATCCTGCGTGGTCGCAGTGGTCAGGCAGCGGAGGGCGGTT
TGCGCTGGATGAGCCTGCTGGCGTGGCTCGGCGGGCTCAGCACCTACCACCTGCTGGCCAATCTTTATCCGGAAGTGGGC
GCAACACTGCCAGCGCTCATTGTCGCTGGCGTGTTGCAACTGCTGATCGGCGGTGCGATCAACCGCGGCCGGGGAACAGT
TCCGGCTTGA

Upstream 100 bases:

>100_bases
TCGCTCCTACGGCCTTCGGCCAGAAGCCCGCTCTGCGTCCGATTCTGAGGGTGCAGTGCGGCTTCACCCGGTTCCTTGAC
TTCCCACACGAGACACCCCT

Downstream 100 bases:

>100_bases
GGATGCCATTGAGCTGAGGATAAGGAATTTTCAGCTCGATGTGACCCATCGAATACGGCGCGATGGTATCGACCGAGTAC
TTGAGGATCACTGCACCGTA

Product: permease for cytosine/purines, uracil, thiamine, allantoin

Products: Proton [Cytoplasm]; cytosine [Cytoplasm] [C]

Alternate protein names: Permease For Cytosine/Purines Uracil Thiamine Allantoin; Permease; Cytosine Permease; CytX-Like Hydroxymethylpyrimidine Transporter Protein; Purine-Cytosine Permease ; Cytosine/Purines/Uracil Permease; NCS1 Nucleoside Transporter

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MNTPGTYSPDTPVPASQRVFGGRDLFSLWFSLGIGLMVLQTGALLAPGLGMSGSMLAIFLGTLAGVLLLASVGVIGSDTG
LSSMAALKLSLGSKGASLPAVLNLLQLIGWGAFEIIVMRDAASLLGARAFAEGSLWSSPLLWTLLFGALATLLAVSGPLT
FVRRFLRKWGLWILLTACAWLTWNLLAKADLTALWATSGDGSLPFASGFDIAIAMPLSWLPLIADYSRFGQRAKSVFGGT
AAGFFIGNFWLMSLGVAYTLAFAPSGEVNALLLALAGAGLGIPLLLILLDETENAFADIHSAAVSSALLSRIKVEHLALV
IGVICTLIACLAPLAQYQNFLLLIGSVFAPLFGVVLVDHFILRGRSGQAAEGGLRWMSLLAWLGGLSTYHLLANLYPEVG
ATLPALIVAGVLQLLIGGAINRGRGTVPA

Sequences:

>Translated_429_residues
MNTPGTYSPDTPVPASQRVFGGRDLFSLWFSLGIGLMVLQTGALLAPGLGMSGSMLAIFLGTLAGVLLLASVGVIGSDTG
LSSMAALKLSLGSKGASLPAVLNLLQLIGWGAFEIIVMRDAASLLGARAFAEGSLWSSPLLWTLLFGALATLLAVSGPLT
FVRRFLRKWGLWILLTACAWLTWNLLAKADLTALWATSGDGSLPFASGFDIAIAMPLSWLPLIADYSRFGQRAKSVFGGT
AAGFFIGNFWLMSLGVAYTLAFAPSGEVNALLLALAGAGLGIPLLLILLDETENAFADIHSAAVSSALLSRIKVEHLALV
IGVICTLIACLAPLAQYQNFLLLIGSVFAPLFGVVLVDHFILRGRSGQAAEGGLRWMSLLAWLGGLSTYHLLANLYPEVG
ATLPALIVAGVLQLLIGGAINRGRGTVPA
>Mature_429_residues
MNTPGTYSPDTPVPASQRVFGGRDLFSLWFSLGIGLMVLQTGALLAPGLGMSGSMLAIFLGTLAGVLLLASVGVIGSDTG
LSSMAALKLSLGSKGASLPAVLNLLQLIGWGAFEIIVMRDAASLLGARAFAEGSLWSSPLLWTLLFGALATLLAVSGPLT
FVRRFLRKWGLWILLTACAWLTWNLLAKADLTALWATSGDGSLPFASGFDIAIAMPLSWLPLIADYSRFGQRAKSVFGGT
AAGFFIGNFWLMSLGVAYTLAFAPSGEVNALLLALAGAGLGIPLLLILLDETENAFADIHSAAVSSALLSRIKVEHLALV
IGVICTLIACLAPLAQYQNFLLLIGSVFAPLFGVVLVDHFILRGRSGQAAEGGLRWMSLLAWLGGLSTYHLLANLYPEVG
ATLPALIVAGVLQLLIGGAINRGRGTVPA

Specific function: Required For Cytosine Transport Into The Cell. [C]

COG id: COG1457

COG function: function code F; Purine-cytosine permease and related proteins

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 44734; Mature: 44734

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTPGTYSPDTPVPASQRVFGGRDLFSLWFSLGIGLMVLQTGALLAPGLGMSGSMLAIFL
CCCCCCCCCCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCHHHHHHHH
GTLAGVLLLASVGVIGSDTGLSSMAALKLSLGSKGASLPAVLNLLQLIGWGAFEIIVMRD
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCHHEEEEEHH
AASLLGARAFAEGSLWSSPLLWTLLFGALATLLAVSGPLTFVRRFLRKWGLWILLTACAW
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
LTWNLLAKADLTALWATSGDGSLPFASGFDIAIAMPLSWLPLIADYSRFGQRAKSVFGGT
HHHHHHHHHHHHEEEEECCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCH
AAGFFIGNFWLMSLGVAYTLAFAPSGEVNALLLALAGAGLGIPLLLILLDETENAFADIH
HHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHH
SAAVSSALLSRIKVEHLALVIGVICTLIACLAPLAQYQNFLLLIGSVFAPLFGVVLVDHF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILRGRSGQAAEGGLRWMSLLAWLGGLSTYHLLANLYPEVGATLPALIVAGVLQLLIGGAI
HHCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCC
NRGRGTVPA
CCCCCCCCC
>Mature Secondary Structure
MNTPGTYSPDTPVPASQRVFGGRDLFSLWFSLGIGLMVLQTGALLAPGLGMSGSMLAIFL
CCCCCCCCCCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCHHHHHHHH
GTLAGVLLLASVGVIGSDTGLSSMAALKLSLGSKGASLPAVLNLLQLIGWGAFEIIVMRD
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCHHEEEEEHH
AASLLGARAFAEGSLWSSPLLWTLLFGALATLLAVSGPLTFVRRFLRKWGLWILLTACAW
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
LTWNLLAKADLTALWATSGDGSLPFASGFDIAIAMPLSWLPLIADYSRFGQRAKSVFGGT
HHHHHHHHHHHHEEEEECCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCH
AAGFFIGNFWLMSLGVAYTLAFAPSGEVNALLLALAGAGLGIPLLLILLDETENAFADIH
HHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHH
SAAVSSALLSRIKVEHLALVIGVICTLIACLAPLAQYQNFLLLIGSVFAPLFGVVLVDHF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILRGRSGQAAEGGLRWMSLLAWLGGLSTYHLLANLYPEVGATLPALIVAGVLQLLIGGAI
HHCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCC
NRGRGTVPA
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; cytosine [Periplasm] [C]

Specific reaction: Proton [Periplasm] + cytosine [Periplasm] = Proton [Cytoplasm] + cytosine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA