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The map label for this gene is gpt [C]

Identifier: 62390351

GI number: 62390351

Start: 1549431

End: 1549907

Strand: Reverse

Name: gpt [C]

Synonym: cg1659

Alternate gene names: 62390351

Gene position: 1549907-1549431 (Counterclockwise)

Preceding gene: 62390357

Following gene: 62390350

Centisome position: 47.21

GC content: 50.94

Gene sequence:

>477_bases
ATGACAGAGGAACGCGAGATTCTGACCTATGAGATGTTCGGAACAGCAATGCGGGAGCTGGCCCAAGAAATTATTGATGA
CTACCAGCCAGATTGCGTGCTGTCCATTGCGCGTGGTGGTCTTCTAATCGGTGGCGCACTTGGTTATGCGCTGGGTATCA
AGAATGTATCGGTGATCAATGTGGAGTTCTACACCGATATTGGAGAGCACTTGGAGGAGCCAATGATGCTGCCTCCAACT
CCAAAAGCTGTTGATCTCTCGGGAATGCGTGTGCTCGTCGCTGACGATGTCGCGGATACCGGAAAGACTCTTGAGTTGGT
CAGGGACTTCCTGGGTGACCAAGTTGTCGAAGTGCGCACTGCAGTGATCTATCACAAGCCAAACAGTGTGTTTAAGCCGG
AGTATGTGTGGCGTGAGACTGATAAGTGGATTAACTTCCCATGGTCTACCCTGCCTCCAGTGGAGCCTTCTAAGTAA

Upstream 100 bases:

>100_bases
TGCTTGGGCGTTAACGATTCTATATATACTTCCCTAGAAATCAAGTGAGCATTCATCTCATTGCAGAACGTTGAAGCATC
ATTGACTAGGATATGTAGAC

Downstream 100 bases:

>100_bases
TTTTTCACCCGTGAAAGTGCTGCTCGCAAATCCTGTGAGCAGCACTTTTTCCAATTTCTACCAAAAATTCCAAAGATCTA
CCCATACTTTTCCCGCGATC

Product: purine phosphoribosyltransferase

Products: Diphosphate; Xanthosine 5'-phosphate [C]

Alternate protein names: Phosphoribosyltransferase; Xanthine-Guanine Phosphoribosyltransferase; Xanthine/Guanine Phosphoribosyltransferase; Phosphoribosyl Transferase Domain-Containing Protein

Number of amino acids: Translated: 158; Mature: 157

Protein sequence:

>158_residues
MTEEREILTYEMFGTAMRELAQEIIDDYQPDCVLSIARGGLLIGGALGYALGIKNVSVINVEFYTDIGEHLEEPMMLPPT
PKAVDLSGMRVLVADDVADTGKTLELVRDFLGDQVVEVRTAVIYHKPNSVFKPEYVWRETDKWINFPWSTLPPVEPSK

Sequences:

>Translated_158_residues
MTEEREILTYEMFGTAMRELAQEIIDDYQPDCVLSIARGGLLIGGALGYALGIKNVSVINVEFYTDIGEHLEEPMMLPPT
PKAVDLSGMRVLVADDVADTGKTLELVRDFLGDQVVEVRTAVIYHKPNSVFKPEYVWRETDKWINFPWSTLPPVEPSK
>Mature_157_residues
TEEREILTYEMFGTAMRELAQEIIDDYQPDCVLSIARGGLLIGGALGYALGIKNVSVINVEFYTDIGEHLEEPMMLPPTP
KAVDLSGMRVLVADDVADTGKTLELVRDFLGDQVVEVRTAVIYHKPNSVFKPEYVWRETDKWINFPWSTLPPVEPSK

Specific function: Acts On Guanine, Xanthine And To A Lesser Extent Hypoxanthine. [C]

COG id: COG2236

COG function: function code R; Predicted phosphoribosyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.4.2.22 [C]

Molecular weight: Translated: 17775; Mature: 17643

Theoretical pI: Translated: 4.24; Mature: 4.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEEREILTYEMFGTAMRELAQEIIDDYQPDCVLSIARGGLLIGGALGYALGIKNVSVIN
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHCCCEEEHHHHHHHHCCCCEEEEE
VEFYTDIGEHLEEPMMLPPTPKAVDLSGMRVLVADDVADTGKTLELVRDFLGDQVVEVRT
EEEHHHHHHHHHCCCCCCCCCCEECCCCCEEEEECCCCCCCHHHHHHHHHHCCHHHHHHH
AVIYHKPNSVFKPEYVWRETDKWINFPWSTLPPVEPSK
EEEEECCCCCCCCCHHCCCCCCEECCCCCCCCCCCCCC
>Mature Secondary Structure 
TEEREILTYEMFGTAMRELAQEIIDDYQPDCVLSIARGGLLIGGALGYALGIKNVSVIN
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHCCCEEEHHHHHHHHCCCCEEEEE
VEFYTDIGEHLEEPMMLPPTPKAVDLSGMRVLVADDVADTGKTLELVRDFLGDQVVEVRT
EEEHHHHHHHHHCCCCCCCCCCEECCCCCEEEEECCCCCCCHHHHHHHHHHCCHHHHHHH
AVIYHKPNSVFKPEYVWRETDKWINFPWSTLPPVEPSK
EEEEECCCCCCCCCHHCCCCCCEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 0.053 {5-phospho-alpha-D-ribose} 0.02 {xanthine}} [C]

Substrates: 5-Phospho-alpha-D-ribose 1-diphosphate; Xanthine [C]

Specific reaction: 5-Phospho-alpha-D-ribose 1-diphosphate + Xanthine --> Diphosphate + Xanthosine 5'-phosphate [C]

General reaction: Glycosyl and Pentosyl group transfer [C]

Inhibitor: 2-Thioxanthine; 6-Thioxanthine; 8-Mercaptoxanthine; ATP; CDP; CTP; GDP; GMP; GTP; TDP; TTP; UDP; UTP; Xanthine; XDP; XMP; XTP [C]

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA