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The map label for this gene is helD [H]

Identifier: 62390258

GI number: 62390258

Start: 1439676

End: 1441943

Strand: Reverse

Name: helD [H]

Synonym: cg1555

Alternate gene names: 62390258

Gene position: 1441943-1439676 (Counterclockwise)

Preceding gene: 62390259

Following gene: 62390256

Centisome position: 43.93

GC content: 55.25

Gene sequence:

>2268_bases
GTGACCACCATTCGGCAATCTGATTCAGAATCAGATGTCCATAACGCCCTCACCACAGCAATTAGCCAAGAACAGGCTTA
TGTTGATGTACTTTTCGGTCGCCTCGATGATGAGGTAGCCAGGTCTAATCAGCGTCTTTCTGAGGTGATGAAAGACGTCG
ACCCCTCAAACCCTGATCCGGAAGCACTTGTTCGTCGTGAAACTGAGTATCACGGCCTGAATGAGAAGTTGGACCGGCTT
AATTTGGCTCAACTCGGGTTGGTCTTCGGTCGAATCGATGTGGAGTCTGAAGCTGAGGACGCTGAGAACCCGGTCCCGGG
CCACCCTGATTTGGATCGTCGTTATATCGGTCGCATGGGTCTTGATGTGCGTGAAGATAATTACCGCACGTTGCTGTTGG
ATTGGCGCTCCCCCATGGCGCGCCCGTTTTATCTGGCCACCACCGTTTCACCGGAGGGCGTGCATATCCGCCGGCACATT
CGCACCCGTGGGCGCGTTGTCACGGGTGTTGATGATGAGGTATTGACCGGTGAGATGGCCGATGTTATCGAGCAGGGTGG
TGTCGGCTCTGAATCTGTGCTGCACCAGGCGTTGGAACAGGCCCGCAGCGGCCACATGCGCAACATCGTTGAAACAATTC
AGCGCGAGCAGGATGAGATCATCCGCGATACCACCCGCGGTGTCATGGTTGTTCAAGGTGGCCCTGGAACAGGTAAAACT
GCGGTCGCGTTGCACCGTGTGGCTTATCTGCTTTATACCTGGCGCGATCAGCTGGCTAAGTCTGGCGTGTTGATCATTGG
CCCGAACAAGACATTTTTGGAGTATATTTCTCACGTTTTGCCTGAACTCGGCGAGACTGGCGTGGTGTTGTCCACCGTCG
GTGAGCTGTTCCCCGGTATCGTCCCAACGGGTTCCGAGGACACTTTGACCAGGGAAATTAAGGGCAGCGAGGAAATGGCC
AGCATTTTGGCCGAGGCAGTCAAGGCGTATCAAGTGCTGCCAGAGAAGACCATCGTGGTCTCTGTTGATGGCATCGAGAT
TTCCATTGATGAGAAAACGGTGGCAAAATCCCGCACCCGAGCTCGTCGTGCCAGGCAGTCGCACAATTCCGCACGCCCAA
TTTTCCGCGAGCATTTAGTCGAACAACTCGCGCACCAAATGGCTCAAACGATCGGCGCGGATCCGCTGGGCGGCAAAAAC
CTGCTGTCAGCCGCCGACATCGATCAGCTGCACGATGATTTGCTTGACGACGCGGCCCTCCAGTCCGTCATCGACGATTT
CTGGCCGGAGCTCCGGCCTCAGGACGTCCTGCATGATCTGTTGATTTCCGAAGAGCGCATTAATGTTGCTGCCGCGGGGT
ATGACGAGGAAACTAAGTCTGCTTTGCTGCGTGGTGAACTCGATCCGTGGGCACCATCGGACGCTGCATTGCTTGATGAG
TTAGCCCTGCTCATCGGTCTTCCCGATCCAGAGGAGGCACGGGAGAAGGCTGAGGCCAAATGGCGCGAGCAGATCGATGA
CGCTCAGGAAGTCCTGGACGTTCTTAGTTCATCACAGTCATCGGATATTGATGATGTCACGGAAGCTGAAGTTCTCTCCG
CTTTCGACGTCATCGATGCGGAAACTTTGGCACAACGCCAAACTGTCACGGATAATCGCACCACTGCGGAACGTGCACAG
GCGGATCATAAGTGGGCGTATGGTCACGTGATTGTAGATGAAGCTCAGGAGCTCAGTCCGATGGAATGGCGCATGGTGTT
TCGCCGTAGCCCTTCGCGATGGATGACCCTTGTGGGCGATATTGCTCAAACTGGTTCGCCTGCCGGCGTTGACGATTGGG
CAGAATCACTGTGGCCCTTCGTCGAAAAGCGTTTCAGGCACCACGAGCTCACCGTTAACTACCGCACCCCGGCCGAGATC
ATGTCGGTGGCCAATGAGCTTTTGACGCAGATCAATCCTGATATTGCGCCGGCAATGGCGATCCGCGAATCTGGTCGAGA
GGTAGTGAACTTGCCGCTTGATGCCGATTTGTCGGCAGTGATGGATAGTTTGCGTGAGGAGGATTCACAGCGCACCATCG
CGGTGATTTCTTCGCGCCGCCACCACGAAAGCGATTTCTACCTGGTCGATGACATCAAGGGCTTAGAGTTTGACCACGTC
ATCGTGGTGGATCCTGCGGGAATCGTTGAAGAATCCCCCCAGGGATTGCAAGACCTCTACGTTGCGGTCACTCGTGCAAC
GCAGAGCCTCACCATTTTAGGTGAGTAG

Upstream 100 bases:

>100_bases
CCGCTATCTGGAATGATTGATAGCTCCCAAGTGTTGTATCTATTCCAGTTCAAACACTTTTTCTCACTGCTCCACATCAG
GAAACAGGAGGTCTCCCGGA

Downstream 100 bases:

>100_bases
CAGGTTATGAGCTCAGGGCCTCAACGATTGAGGTGCTCGGGCGTCCGATGAGATCCTGTAGGTCGGTGCTGTCGGAGTAC
AGCGCGCCCTCTGCAATGAT

Product: superfamily I DNA/RNA helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 755; Mature: 754

Protein sequence:

>755_residues
MTTIRQSDSESDVHNALTTAISQEQAYVDVLFGRLDDEVARSNQRLSEVMKDVDPSNPDPEALVRRETEYHGLNEKLDRL
NLAQLGLVFGRIDVESEAEDAENPVPGHPDLDRRYIGRMGLDVREDNYRTLLLDWRSPMARPFYLATTVSPEGVHIRRHI
RTRGRVVTGVDDEVLTGEMADVIEQGGVGSESVLHQALEQARSGHMRNIVETIQREQDEIIRDTTRGVMVVQGGPGTGKT
AVALHRVAYLLYTWRDQLAKSGVLIIGPNKTFLEYISHVLPELGETGVVLSTVGELFPGIVPTGSEDTLTREIKGSEEMA
SILAEAVKAYQVLPEKTIVVSVDGIEISIDEKTVAKSRTRARRARQSHNSARPIFREHLVEQLAHQMAQTIGADPLGGKN
LLSAADIDQLHDDLLDDAALQSVIDDFWPELRPQDVLHDLLISEERINVAAAGYDEETKSALLRGELDPWAPSDAALLDE
LALLIGLPDPEEAREKAEAKWREQIDDAQEVLDVLSSSQSSDIDDVTEAEVLSAFDVIDAETLAQRQTVTDNRTTAERAQ
ADHKWAYGHVIVDEAQELSPMEWRMVFRRSPSRWMTLVGDIAQTGSPAGVDDWAESLWPFVEKRFRHHELTVNYRTPAEI
MSVANELLTQINPDIAPAMAIRESGREVVNLPLDADLSAVMDSLREEDSQRTIAVISSRRHHESDFYLVDDIKGLEFDHV
IVVDPAGIVEESPQGLQDLYVAVTRATQSLTILGE

Sequences:

>Translated_755_residues
MTTIRQSDSESDVHNALTTAISQEQAYVDVLFGRLDDEVARSNQRLSEVMKDVDPSNPDPEALVRRETEYHGLNEKLDRL
NLAQLGLVFGRIDVESEAEDAENPVPGHPDLDRRYIGRMGLDVREDNYRTLLLDWRSPMARPFYLATTVSPEGVHIRRHI
RTRGRVVTGVDDEVLTGEMADVIEQGGVGSESVLHQALEQARSGHMRNIVETIQREQDEIIRDTTRGVMVVQGGPGTGKT
AVALHRVAYLLYTWRDQLAKSGVLIIGPNKTFLEYISHVLPELGETGVVLSTVGELFPGIVPTGSEDTLTREIKGSEEMA
SILAEAVKAYQVLPEKTIVVSVDGIEISIDEKTVAKSRTRARRARQSHNSARPIFREHLVEQLAHQMAQTIGADPLGGKN
LLSAADIDQLHDDLLDDAALQSVIDDFWPELRPQDVLHDLLISEERINVAAAGYDEETKSALLRGELDPWAPSDAALLDE
LALLIGLPDPEEAREKAEAKWREQIDDAQEVLDVLSSSQSSDIDDVTEAEVLSAFDVIDAETLAQRQTVTDNRTTAERAQ
ADHKWAYGHVIVDEAQELSPMEWRMVFRRSPSRWMTLVGDIAQTGSPAGVDDWAESLWPFVEKRFRHHELTVNYRTPAEI
MSVANELLTQINPDIAPAMAIRESGREVVNLPLDADLSAVMDSLREEDSQRTIAVISSRRHHESDFYLVDDIKGLEFDHV
IVVDPAGIVEESPQGLQDLYVAVTRATQSLTILGE
>Mature_754_residues
TTIRQSDSESDVHNALTTAISQEQAYVDVLFGRLDDEVARSNQRLSEVMKDVDPSNPDPEALVRRETEYHGLNEKLDRLN
LAQLGLVFGRIDVESEAEDAENPVPGHPDLDRRYIGRMGLDVREDNYRTLLLDWRSPMARPFYLATTVSPEGVHIRRHIR
TRGRVVTGVDDEVLTGEMADVIEQGGVGSESVLHQALEQARSGHMRNIVETIQREQDEIIRDTTRGVMVVQGGPGTGKTA
VALHRVAYLLYTWRDQLAKSGVLIIGPNKTFLEYISHVLPELGETGVVLSTVGELFPGIVPTGSEDTLTREIKGSEEMAS
ILAEAVKAYQVLPEKTIVVSVDGIEISIDEKTVAKSRTRARRARQSHNSARPIFREHLVEQLAHQMAQTIGADPLGGKNL
LSAADIDQLHDDLLDDAALQSVIDDFWPELRPQDVLHDLLISEERINVAAAGYDEETKSALLRGELDPWAPSDAALLDEL
ALLIGLPDPEEAREKAEAKWREQIDDAQEVLDVLSSSQSSDIDDVTEAEVLSAFDVIDAETLAQRQTVTDNRTTAERAQA
DHKWAYGHVIVDEAQELSPMEWRMVFRRSPSRWMTLVGDIAQTGSPAGVDDWAESLWPFVEKRFRHHELTVNYRTPAEIM
SVANELLTQINPDIAPAMAIRESGREVVNLPLDADLSAVMDSLREEDSQRTIAVISSRRHHESDFYLVDDIKGLEFDHVI
VVDPAGIVEESPQGLQDLYVAVTRATQSLTILGE

Specific function: Catalyzes the unwinding of duplex DNA in the 3' to 5' direction; this reaction is dependent on the hydrolysis of ATP [H]

COG id: COG3973

COG function: function code R; Superfamily I DNA and RNA helicases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 uvrD-like helicase ATP-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000212
- InterPro:   IPR014016 [H]

Pfam domain/function: PF00580 UvrD-helicase [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 83984; Mature: 83853

Theoretical pI: Translated: 4.37; Mature: 4.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTIRQSDSESDVHNALTTAISQEQAYVDVLFGRLDDEVARSNQRLSEVMKDVDPSNPDP
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
EALVRRETEYHGLNEKLDRLNLAQLGLVFGRIDVESEAEDAENPVPGHPDLDRRYIGRMG
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCCCCCCHHHHHHHHCC
LDVREDNYRTLLLDWRSPMARPFYLATTVSPEGVHIRRHIRTRGRVVTGVDDEVLTGEMA
CCEECCCCEEEEEECCCCCCCCEEEEEECCCCCHHHHHHHHHCCCEEECCCCHHHCCHHH
DVIEQGGVGSESVLHQALEQARSGHMRNIVETIQREQDEIIRDTTRGVMVVQGGPGTGKT
HHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHH
AVALHRVAYLLYTWRDQLAKSGVLIIGPNKTFLEYISHVLPELGETGVVLSTVGELFPGI
HHHHHHHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCC
VPTGSEDTLTREIKGSEEMASILAEAVKAYQVLPEKTIVVSVDGIEISIDEKTVAKSRTR
CCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCEEEEECHHHHHHHHHH
ARRARQSHNSARPIFREHLVEQLAHQMAQTIGADPLGGKNLLSAADIDQLHDDLLDDAAL
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
QSVIDDFWPELRPQDVLHDLLISEERINVAAAGYDEETKSALLRGELDPWAPSDAALLDE
HHHHHHHCCCCCHHHHHHHHHHHHHHCEEEECCCCHHHHHHHHHCCCCCCCCCHHHHHHH
LALLIGLPDPEEAREKAEAKWREQIDDAQEVLDVLSSSQSSDIDDVTEAEVLSAFDVIDA
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
ETLAQRQTVTDNRTTAERAQADHKWAYGHVIVDEAQELSPMEWRMVFRRSPSRWMTLVGD
HHHHHHHHCCCCCHHHHHHHCCCCEEECEEEECCHHHCCCHHHHHHHHCCCHHHHHHHHH
IAQTGSPAGVDDWAESLWPFVEKRFRHHELTVNYRTPAEIMSVANELLTQINPDIAPAMA
HHHCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHCCCCHHHHHH
IRESGREVVNLPLDADLSAVMDSLREEDSQRTIAVISSRRHHESDFYLVDDIKGLEFDHV
HHHCCCCEEECCCCCCHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCEEEECCCCCCCCCE
IVVDPAGIVEESPQGLQDLYVAVTRATQSLTILGE
EEECCCHHHCCCCCHHHHHHHHHHHHHCCEEEECC
>Mature Secondary Structure 
TTIRQSDSESDVHNALTTAISQEQAYVDVLFGRLDDEVARSNQRLSEVMKDVDPSNPDP
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
EALVRRETEYHGLNEKLDRLNLAQLGLVFGRIDVESEAEDAENPVPGHPDLDRRYIGRMG
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCCCCCCHHHHHHHHCC
LDVREDNYRTLLLDWRSPMARPFYLATTVSPEGVHIRRHIRTRGRVVTGVDDEVLTGEMA
CCEECCCCEEEEEECCCCCCCCEEEEEECCCCCHHHHHHHHHCCCEEECCCCHHHCCHHH
DVIEQGGVGSESVLHQALEQARSGHMRNIVETIQREQDEIIRDTTRGVMVVQGGPGTGKT
HHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHH
AVALHRVAYLLYTWRDQLAKSGVLIIGPNKTFLEYISHVLPELGETGVVLSTVGELFPGI
HHHHHHHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCC
VPTGSEDTLTREIKGSEEMASILAEAVKAYQVLPEKTIVVSVDGIEISIDEKTVAKSRTR
CCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCEEEEECHHHHHHHHHH
ARRARQSHNSARPIFREHLVEQLAHQMAQTIGADPLGGKNLLSAADIDQLHDDLLDDAAL
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
QSVIDDFWPELRPQDVLHDLLISEERINVAAAGYDEETKSALLRGELDPWAPSDAALLDE
HHHHHHHCCCCCHHHHHHHHHHHHHHCEEEECCCCHHHHHHHHHCCCCCCCCCHHHHHHH
LALLIGLPDPEEAREKAEAKWREQIDDAQEVLDVLSSSQSSDIDDVTEAEVLSAFDVIDA
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
ETLAQRQTVTDNRTTAERAQADHKWAYGHVIVDEAQELSPMEWRMVFRRSPSRWMTLVGD
HHHHHHHHCCCCCHHHHHHHCCCCEEECEEEECCHHHCCCHHHHHHHHCCCHHHHHHHHH
IAQTGSPAGVDDWAESLWPFVEKRFRHHELTVNYRTPAEIMSVANELLTQINPDIAPAMA
HHHCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHCCCCHHHHHH
IRESGREVVNLPLDADLSAVMDSLREEDSQRTIAVISSRRHHESDFYLVDDIKGLEFDHV
HHHCCCCEEECCCCCCHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCEEEECCCCCCCCCE
IVVDPAGIVEESPQGLQDLYVAVTRATQSLTILGE
EEECCCHHHCCCCCHHHHHHHHHHHHHCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]