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The map label for this gene is moeA3 [H]

Identifier: 62390084

GI number: 62390084

Start: 1261458

End: 1262669

Strand: Reverse

Name: moeA3 [H]

Synonym: cg1351

Alternate gene names: 62390084

Gene position: 1262669-1261458 (Counterclockwise)

Preceding gene: 62390085

Following gene: 62390083

Centisome position: 38.46

GC content: 54.21

Gene sequence:

>1212_bases
GTGGCACAGCAACGCAGCGTCGATGACTATCTTTCCATTTTGATAGACAGCGTCGCACCGCTTCCGCCAGTAAAAACCCT
TATCCTCGGCGCGCATCCGTTAAGTCACCTTGCAGAGGATGTTGTCGCGACAATTCCTATCCCGAAATTTACTAATTCTG
CTGTTGATGGTTACGCCATTTTGAAAGAAGACATCCATGGCAGCGGGCCGTGGACATTTCTTGTGGGCGGTGATACTCCG
GCGGGTTCTGCGCCGGCGAGCATTAATAATGGAAAAGCCATCCGTGTGATGACAGGTGGACCCGTCCCATCCACCAACAA
GGACATGATCGTGGTTCCAGTGGAGCTCACCAATGCTCCGGTGGATCACTCGCTTCCTACAGAAATCACGATCAATGAGC
TACCAGGTGAGAGGAATAATATTCGCCATGCTGGTGAGCATCTTAAAGAAGGCGAAATTGCGGTTGCTGCGGGGACGGCA
TTTGATGCGGGTACTGTGTCGACGGTGATTTCAGTTGGCCATGACACTGTAAAAGCCCATCCTTGCCCTCGGGTTGCGGT
GATCACTACCGGTGATGAGCTAAACCAGGGAAATCCCTGGGGTATCCCTAATTCCAATGGGCCGATGCTGGTTGCGGAGC
TAAAACGCGTGGGGATTAAGGATCCGCAGCATTTCCATTCCGATGATTCTGAGACTGCATTGAGGGAGACGCTCGATAAG
GCTGCAGAGGTTGCGGATGTGATCATCACTGTGGGTGGGATCTCGGCGGGCGCGTTCGATGTGGTCAAAGCCGTGGGAAC
TAAGACTGGTGGTTTTGAATTCTTCCCCATTGCGATGAAGCCGGGTAAACCGCAAGGTCATGGGCAGTGGGGCGACGCAA
AAGTGGTGTGTCTGCCGGGAAACCCGGTGGCGGCGTGGGTTAGTTTTAGGCTCTTTGTTGTTCCGGTAATTGAGAGATTA
GGGGGTGGAAAGAGGCTGGCGTCGATAAGCGAACTCCCTGTGGTGGCGCTGCGCTCGAACCGGGCGCTGAAGGCGCGGGA
GGGCGCCGTATTGGCGATACCGGTGGCGATTGATTGGGAGAAAAGAATGGCAAATTCTCAGGCACATCGATCCCATATGG
TCGGTGCACTGGCTGGAAGTGGCGGTATTGCACTGGTGACTTCGTCGATTGCCGAGGACGGTCTGGTTGATGTTGTGCTG
GGGAGAATGTAA

Upstream 100 bases:

>100_bases
ACACCCGTTTGAGAATCTCAACCTCTTAAAACAGCGCGAACTATTGATTTGGCAACTACCCTATATATTTGAGTGTTTAT
TGTCGAAAAAGGGGTTTCAA

Downstream 100 bases:

>100_bases
ATGAATATCATCATTCTTGCTGGTGGCGAGGGTAAACGCATGGGTGGGGTGGATAAGGCTGCTGTGGCGGTGGATGGTCG
CACGCTGCTGGATATCCTGC

Product: molybdopterin biosynthesis protein

Products: NA

Alternate protein names: MPT Mo-transferase [H]

Number of amino acids: Translated: 403; Mature: 402

Protein sequence:

>403_residues
MAQQRSVDDYLSILIDSVAPLPPVKTLILGAHPLSHLAEDVVATIPIPKFTNSAVDGYAILKEDIHGSGPWTFLVGGDTP
AGSAPASINNGKAIRVMTGGPVPSTNKDMIVVPVELTNAPVDHSLPTEITINELPGERNNIRHAGEHLKEGEIAVAAGTA
FDAGTVSTVISVGHDTVKAHPCPRVAVITTGDELNQGNPWGIPNSNGPMLVAELKRVGIKDPQHFHSDDSETALRETLDK
AAEVADVIITVGGISAGAFDVVKAVGTKTGGFEFFPIAMKPGKPQGHGQWGDAKVVCLPGNPVAAWVSFRLFVVPVIERL
GGGKRLASISELPVVALRSNRALKAREGAVLAIPVAIDWEKRMANSQAHRSHMVGALAGSGGIALVTSSIAEDGLVDVVL
GRM

Sequences:

>Translated_403_residues
MAQQRSVDDYLSILIDSVAPLPPVKTLILGAHPLSHLAEDVVATIPIPKFTNSAVDGYAILKEDIHGSGPWTFLVGGDTP
AGSAPASINNGKAIRVMTGGPVPSTNKDMIVVPVELTNAPVDHSLPTEITINELPGERNNIRHAGEHLKEGEIAVAAGTA
FDAGTVSTVISVGHDTVKAHPCPRVAVITTGDELNQGNPWGIPNSNGPMLVAELKRVGIKDPQHFHSDDSETALRETLDK
AAEVADVIITVGGISAGAFDVVKAVGTKTGGFEFFPIAMKPGKPQGHGQWGDAKVVCLPGNPVAAWVSFRLFVVPVIERL
GGGKRLASISELPVVALRSNRALKAREGAVLAIPVAIDWEKRMANSQAHRSHMVGALAGSGGIALVTSSIAEDGLVDVVL
GRM
>Mature_402_residues
AQQRSVDDYLSILIDSVAPLPPVKTLILGAHPLSHLAEDVVATIPIPKFTNSAVDGYAILKEDIHGSGPWTFLVGGDTPA
GSAPASINNGKAIRVMTGGPVPSTNKDMIVVPVELTNAPVDHSLPTEITINELPGERNNIRHAGEHLKEGEIAVAAGTAF
DAGTVSTVISVGHDTVKAHPCPRVAVITTGDELNQGNPWGIPNSNGPMLVAELKRVGIKDPQHFHSDDSETALRETLDKA
AEVADVIITVGGISAGAFDVVKAVGTKTGGFEFFPIAMKPGKPQGHGQWGDAKVVCLPGNPVAAWVSFRLFVVPVIERLG
GGKRLASISELPVVALRSNRALKAREGAVLAIPVAIDWEKRMANSQAHRSHMVGALAGSGGIALVTSSIAEDGLVDVVLG
RM

Specific function: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP [H]

COG id: COG0303

COG function: function code H; Molybdopterin biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moeA family [H]

Homologues:

Organism=Homo sapiens, GI66932975, Length=300, Percent_Identity=33, Blast_Score=115, Evalue=8e-26,
Organism=Homo sapiens, GI10880983, Length=300, Percent_Identity=33, Blast_Score=115, Evalue=9e-26,
Organism=Escherichia coli, GI1787049, Length=326, Percent_Identity=32.8220858895706, Blast_Score=132, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI25147659, Length=302, Percent_Identity=29.4701986754967, Blast_Score=108, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17562606, Length=369, Percent_Identity=27.3712737127371, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI17136978, Length=356, Percent_Identity=29.2134831460674, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24638841, Length=356, Percent_Identity=29.2134831460674, Blast_Score=96, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020817
- InterPro:   IPR008284
- InterPro:   IPR005111
- InterPro:   IPR005110
- InterPro:   IPR001453 [H]

Pfam domain/function: PF00994 MoCF_biosynth; PF03454 MoeA_C; PF03453 MoeA_N [H]

EC number: NA

Molecular weight: Translated: 42053; Mature: 41921

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQQRSVDDYLSILIDSVAPLPPVKTLILGAHPLSHLAEDVVATIPIPKFTNSAVDGYAI
CCCCCCHHHHHHHHHHHCCCCCCHHHEEECCCHHHHHHHHHHEECCCCCCCCCCCCCCEE
LKEDIHGSGPWTFLVGGDTPAGSAPASINNGKAIRVMTGGPVPSTNKDMIVVPVELTNAP
EHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCEEEEEEEECCCC
VDHSLPTEITINELPGERNNIRHAGEHLKEGEIAVAAGTAFDAGTVSTVISVGHDTVKAH
CCCCCCCEEEEECCCCCCCCHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHCCCCCEECC
PCPRVAVITTGDELNQGNPWGIPNSNGPMLVAELKRVGIKDPQHFHSDDSETALRETLDK
CCCEEEEEECCCCCCCCCCCCCCCCCCCEEEEEHHHCCCCCCHHHCCCCHHHHHHHHHHH
AAEVADVIITVGGISAGAFDVVKAVGTKTGGFEFFPIAMKPGKPQGHGQWGDAKVVCLPG
HHHHEEEEEEECCCCCCHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCCEEEEEECC
NPVAAWVSFRLFVVPVIERLGGGKRLASISELPVVALRSNRALKAREGAVLAIPVAIDWE
CCHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCEEEEECCCCEEECCCCEEEEEEEECHH
KRMANSQAHRSHMVGALAGSGGIALVTSSIAEDGLVDVVLGRM
HHHCCHHHHHHHHEEEEECCCCEEEEEHHHCCCCCHHHHCCCC
>Mature Secondary Structure 
AQQRSVDDYLSILIDSVAPLPPVKTLILGAHPLSHLAEDVVATIPIPKFTNSAVDGYAI
CCCCCHHHHHHHHHHHCCCCCCHHHEEECCCHHHHHHHHHHEECCCCCCCCCCCCCCEE
LKEDIHGSGPWTFLVGGDTPAGSAPASINNGKAIRVMTGGPVPSTNKDMIVVPVELTNAP
EHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCEEEEEEEECCCC
VDHSLPTEITINELPGERNNIRHAGEHLKEGEIAVAAGTAFDAGTVSTVISVGHDTVKAH
CCCCCCCEEEEECCCCCCCCHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHCCCCCEECC
PCPRVAVITTGDELNQGNPWGIPNSNGPMLVAELKRVGIKDPQHFHSDDSETALRETLDK
CCCEEEEEECCCCCCCCCCCCCCCCCCCEEEEEHHHCCCCCCHHHCCCCHHHHHHHHHHH
AAEVADVIITVGGISAGAFDVVKAVGTKTGGFEFFPIAMKPGKPQGHGQWGDAKVVCLPG
HHHHEEEEEEECCCCCCHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCCEEEEEECC
NPVAAWVSFRLFVVPVIERLGGGKRLASISELPVVALRSNRALKAREGAVLAIPVAIDWE
CCHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCEEEEECCCCEEECCCCEEEEEEEECHH
KRMANSQAHRSHMVGALAGSGGIALVTSSIAEDGLVDVVLGRM
HHHCCHHHHHHHHEEEEECCCCEEEEEHHHCCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]