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The map label for this gene is ytfL [C]

Identifier: 62390082

GI number: 62390082

Start: 1259330

End: 1260733

Strand: Reverse

Name: ytfL [C]

Synonym: cg1349

Alternate gene names: 62390082

Gene position: 1260733-1259330 (Counterclockwise)

Preceding gene: 62390083

Following gene: 62390081

Centisome position: 38.41

GC content: 50.0

Gene sequence:

>1404_bases
TTGTTAACAGCTGTTTTGTCTTTAATTGCTGGTTTGGTGGTCATTGGGGTGATCATCGTCCTCAACGGATATTTTGTGGC
TCAGGAATTTGCCTACATGTCCGTTGATCGAAATGAGCTGCGAGCTCTCGCTGACTCTGGAGATAAGAAGGCTCGTCGCG
CTCTCAGCATCACTAAGCGCACATCCTTTATGCTTTCTGGTGCGCAATTGGGTATCACCGTCACCGGACTTTTGGTGGGT
TTTGTGGCCGAACCTCTGGTGGGTAACGCGTTAGGTGTTCTGCTAGGAGGGGTGGGGGTTCCCGCTGCGGTGTCAATCTC
TGTGGGCACTGTGTTGGCGCTAGCGATCTCCACGGTTGTCCAAATGATTTTTGGTGAACTCTTCCCTAAGAACTACACCC
TTGCCACGCCGTTGAAGTCTGCGCTGGCGCTTGCGCCTTCGACCACGTGGTATTTGAAACTCGCTGGTTGGTTGATCACA
TTCTTTGATTTTGCATCCAACGCATTGCTTCGACTCTTTCGAATAGAGCCGGTGGAAGATGTTGATTCGTCTGCCACTGC
ACAAGACCTTCCGCATATTGTGGCGTCATCTAGGGATAGTGGCGTTTTAAATAATTCGATGTCTTTGTCGCTTGATCGAT
TGTTGGATTTCCCGTCGCATGATGTGGGTCATGCAATGATTCCGCGTTCGCGTGTGGGTGTGGTTGATCCGGAGACAACC
ATCGCTGAGGTTAAGGCCCTCATGAGGAAAGCGCATACGCGTTACCCCATCATCGATGACAACCATGTGCCCATTGGGGT
GATCAATCTGATTGATATTCTTGGAACCGATATTCACGGCGCCGAAATTTCAGATTCCGCGAAAGTCACTGAGTTCATGC
ATCAGCCTGTGATCGTTCCAGAGTTTATGTCTTTGCCTGACGTGGTGACCGAACTGCACAATCGTGAAGACAGGCTTGCT
TGCGTGATTGATGAATACGGTGGATTCATTGGCATTGTGACATTAGAAGATTTAGCTGAGGAAGTCCTCGGCGATATCAA
CGATGAGCACGATGTTTTCAGCTCTGAAGATATTACGGAAACGAGCCCTGACAAATGGCTAATTGATGGCGATACCCCTC
TTGACGAGGTTGAGCGCGCCATCGGGTACGAGCTACCTGAAGGCGATTACGAGACGATTTCTGGACTGCTCTTTGACCAT
GCGAATGCCCTTCTAAAGACTGGGGATGTCATAGAAATACCTCTGGATTTTGAGCCAGAGGATTACCTGAACAACACCTC
CCCTACGCAGCGTATTTTGCGCATCACTGTTTTAGAGGTAGAGCGAAACGTGCCTGTAAAACTGGCGCTCGCTCTGCTCG
AAGACCACCCAGACAATCACCCCGCTCCGAAGGAGAATCGCTAA

Upstream 100 bases:

>100_bases
ACCGACTTGAATGAATGAGGTTTAGACTCCGCATGGAGCCTCCCGCACGATCTATCTGGCCTGTCCACACTAATCTATTT
GTGTTGAGGCAGGTGGAATC

Downstream 100 bases:

>100_bases
GCCATGACTGAATGGTATGTCGTTTTACCCGCCACTATTCTACTCATCGCGCTGTCTGCGTTTTTCGTCATCATTGAGTT
CGCTTTGCTTGCAGCTAGGC

Product: CBS domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 467; Mature: 467

Protein sequence:

>467_residues
MLTAVLSLIAGLVVIGVIIVLNGYFVAQEFAYMSVDRNELRALADSGDKKARRALSITKRTSFMLSGAQLGITVTGLLVG
FVAEPLVGNALGVLLGGVGVPAAVSISVGTVLALAISTVVQMIFGELFPKNYTLATPLKSALALAPSTTWYLKLAGWLIT
FFDFASNALLRLFRIEPVEDVDSSATAQDLPHIVASSRDSGVLNNSMSLSLDRLLDFPSHDVGHAMIPRSRVGVVDPETT
IAEVKALMRKAHTRYPIIDDNHVPIGVINLIDILGTDIHGAEISDSAKVTEFMHQPVIVPEFMSLPDVVTELHNREDRLA
CVIDEYGGFIGIVTLEDLAEEVLGDINDEHDVFSSEDITETSPDKWLIDGDTPLDEVERAIGYELPEGDYETISGLLFDH
ANALLKTGDVIEIPLDFEPEDYLNNTSPTQRILRITVLEVERNVPVKLALALLEDHPDNHPAPKENR

Sequences:

>Translated_467_residues
MLTAVLSLIAGLVVIGVIIVLNGYFVAQEFAYMSVDRNELRALADSGDKKARRALSITKRTSFMLSGAQLGITVTGLLVG
FVAEPLVGNALGVLLGGVGVPAAVSISVGTVLALAISTVVQMIFGELFPKNYTLATPLKSALALAPSTTWYLKLAGWLIT
FFDFASNALLRLFRIEPVEDVDSSATAQDLPHIVASSRDSGVLNNSMSLSLDRLLDFPSHDVGHAMIPRSRVGVVDPETT
IAEVKALMRKAHTRYPIIDDNHVPIGVINLIDILGTDIHGAEISDSAKVTEFMHQPVIVPEFMSLPDVVTELHNREDRLA
CVIDEYGGFIGIVTLEDLAEEVLGDINDEHDVFSSEDITETSPDKWLIDGDTPLDEVERAIGYELPEGDYETISGLLFDH
ANALLKTGDVIEIPLDFEPEDYLNNTSPTQRILRITVLEVERNVPVKLALALLEDHPDNHPAPKENR
>Mature_467_residues
MLTAVLSLIAGLVVIGVIIVLNGYFVAQEFAYMSVDRNELRALADSGDKKARRALSITKRTSFMLSGAQLGITVTGLLVG
FVAEPLVGNALGVLLGGVGVPAAVSISVGTVLALAISTVVQMIFGELFPKNYTLATPLKSALALAPSTTWYLKLAGWLIT
FFDFASNALLRLFRIEPVEDVDSSATAQDLPHIVASSRDSGVLNNSMSLSLDRLLDFPSHDVGHAMIPRSRVGVVDPETT
IAEVKALMRKAHTRYPIIDDNHVPIGVINLIDILGTDIHGAEISDSAKVTEFMHQPVIVPEFMSLPDVVTELHNREDRLA
CVIDEYGGFIGIVTLEDLAEEVLGDINDEHDVFSSEDITETSPDKWLIDGDTPLDEVERAIGYELPEGDYETISGLLFDH
ANALLKTGDVIEIPLDFEPEDYLNNTSPTQRILRITVLEVERNVPVKLALALLEDHPDNHPAPKENR

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=414, Percent_Identity=26.3285024154589, Blast_Score=159, Evalue=4e-39,
Organism=Escherichia coli, GI1790664, Length=410, Percent_Identity=23.6585365853659, Blast_Score=126, Evalue=3e-30,
Organism=Escherichia coli, GI145693175, Length=395, Percent_Identity=25.8227848101266, Blast_Score=108, Evalue=7e-25,
Organism=Escherichia coli, GI87082033, Length=353, Percent_Identity=23.5127478753541, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI1786879, Length=307, Percent_Identity=27.0358306188925, Blast_Score=77, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 50761; Mature: 50761

Theoretical pI: Translated: 4.29; Mature: 4.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTAVLSLIAGLVVIGVIIVLNGYFVAQEFAYMSVDRNELRALADSGDKKARRALSITKR
CHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHH
TSFMLSGAQLGITVTGLLVGFVAEPLVGNALGVLLGGVGVPAAVSISVGTVLALAISTVV
HHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHH
QMIFGELFPKNYTLATPLKSALALAPSTTWYLKLAGWLITFFDFASNALLRLFRIEPVED
HHHHHHHCCCCCEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VDSSATAQDLPHIVASSRDSGVLNNSMSLSLDRLLDFPSHDVGHAMIPRSRVGVVDPETT
CCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHH
IAEVKALMRKAHTRYPIIDDNHVPIGVINLIDILGTDIHGAEISDSAKVTEFMHQPVIVP
HHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCH
EFMSLPDVVTELHNREDRLACVIDEYGGFIGIVTLEDLAEEVLGDINDEHDVFSSEDITE
HHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEEHHHHHHHHHHCCCCCCCCCCCCCCCC
TSPDKWLIDGDTPLDEVERAIGYELPEGDYETISGLLFDHANALLKTGDVIEIPLDFEPE
CCCCCEEECCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCH
DYLNNTSPTQRILRITVLEVERNVPVKLALALLEDHPDNHPAPKENR
HHCCCCCHHHHHHHHEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MLTAVLSLIAGLVVIGVIIVLNGYFVAQEFAYMSVDRNELRALADSGDKKARRALSITKR
CHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHH
TSFMLSGAQLGITVTGLLVGFVAEPLVGNALGVLLGGVGVPAAVSISVGTVLALAISTVV
HHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHH
QMIFGELFPKNYTLATPLKSALALAPSTTWYLKLAGWLITFFDFASNALLRLFRIEPVED
HHHHHHHCCCCCEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VDSSATAQDLPHIVASSRDSGVLNNSMSLSLDRLLDFPSHDVGHAMIPRSRVGVVDPETT
CCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHH
IAEVKALMRKAHTRYPIIDDNHVPIGVINLIDILGTDIHGAEISDSAKVTEFMHQPVIVP
HHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCH
EFMSLPDVVTELHNREDRLACVIDEYGGFIGIVTLEDLAEEVLGDINDEHDVFSSEDITE
HHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEEHHHHHHHHHHCCCCCCCCCCCCCCCC
TSPDKWLIDGDTPLDEVERAIGYELPEGDYETISGLLFDHANALLKTGDVIEIPLDFEPE
CCCCCEEECCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCH
DYLNNTSPTQRILRITVLEVERNVPVKLALALLEDHPDNHPAPKENR
HHCCCCCHHHHHHHHEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]