Click here to switch to the map view.

The map label for this gene is tap [H]

Identifier: 62390066

GI number: 62390066

Start: 1238010

End: 1239593

Strand: Reverse

Name: tap [H]

Synonym: cg1332

Alternate gene names: 62390066

Gene position: 1239593-1238010 (Counterclockwise)

Preceding gene: 62390069

Following gene: 62390061

Centisome position: 37.76

GC content: 58.27

Gene sequence:

>1584_bases
ATGCCCCGTTCGACAATAAAAAGGGTAGTAGCAGTTCTTGCCGCCTCGACTGCGCTTAGCCCCTTTTTGGTATCAATGCC
CACTGCAGCAGCGCAAGAAAACATCCGCTGGGAAGAATGCCCACCTCAGGTAGATATTGCCTCCGCTCAATGTGGCAGCA
TCGACGTGCCCATGCACTATTCTGATCCCTCACTTGGCGATATCAGCGTGGGCTTTGTCAAGGTCCCTGCCCAAGGCGAA
AAGCACGGCACCATCTTCGGTAACTCCGGTGGCCCTGGTGGCGATGCCTATAGCTTCTTCGGCAGCCAATCCATGAACTG
GCCAGAAGCCATGTACCAAAACTACGACCTCGTTGCAGTGCAGCCTCGCGGAATGGTCGGCTCCACACCGGTTAACTGCG
ACAACATCGCACCAGGATACGATTTCCTCTCGCTGCTCACCCGCGAAGGCGCTTTCGTTAAAGAATCCTGCGAGATCGGC
ACCCCCGGCTACACCTCCAGCCTGACCACCGACAACACCGCCAACGACTGGGAGCGCGTCCGCCAAGCACTTGGCGATGA
CAAGATCTCCATCTTCGGACTGTCCTACGGAACCTACCTCGGATCGGTCTACGCCACCCGCTACCCACAGCACACCGACA
AGGTTGTCCTCGATTCCGCAATGGCGCCCAGCCTGGCATGGAACGGCATCATGGCCTCCCAAGAACAGGGCTACAAAAAC
TCCCTCAACGACTTCTTCACCTGGGTTGCAGAAAACAACGACACGTATGGCCTCGGCACTACCCCACTAGCCGTGTACCA
AAACTGGTCAAACAAGATCGTCGCCGAAACCGGAACCAACCCAACCGTTGCTCCACCACCAGCACAAGTTGGCGATGTCC
CACCAGCATTCGCATGGGCCGGCCAAGCAGGCGCAGACATGATGACCGCCACCAACCCAACCTCCGTGCAACTCCAGGGC
CTTGCCACCCAGCTCCTAAACCCTGGATCCAACCAGTCACTGAGCCCTCTGCTCAACGTCACCCGCGCCTACATCCCACA
GCCATCAACCTGGCCCATGCTCGCAGGCGCCATCTCAGGGCAAACACCCATCCCTGACGTAACTGACACCGGCGACGACC
CATACGTCATCGAAAGCATCAACGCCAGCGTCAACATGCAGCGCATGGTCATGTGCAACGAAAACACCGTCGCACCAGAC
CCAGTAGCAATGGCACGCATGGCCTGGACAAGCATGGTCACCGGCGACGTCTTTGACATTTACTCCGTTAAATTCAGCTC
CGGACAAGCCTGCTCCGGCATCACCCCAACAAGCGGCCGCCAGCCAACCGACGGATCTCAACTAGCAGTCCAACCACTAC
TCCTCCAGGGAACCAGCGACCCACAAACCCCATACTGGACCCACAACGAGCTTGCCGACGCCATGAACGCCCACGTGGTC
ACCGTCAACGGACCAGGACACGGCCAATCCATCGGCGGCACCAACCAAGCAATCAACGACATTGTTGTGGACTACCTCCG
CACCGGACACACCGACGCCACCTGGGTCGAAGGCAACACACCCACCCCAATTACGGCTGGCTAA

Upstream 100 bases:

>100_bases
TACTTATAACAAATCCCTGCCTTTTTAATGAAAAATCATTGGTCTCTGTATATGCTTTTTGGGGTAACTGACCCAGAAAA
CAAACGTCCTTGGAGCCGTA

Downstream 100 bases:

>100_bases
TTGCTTTCCACTTAGTAGATGGTGATAGAATCACACCGTTGTCATCACCCACTAAAGGAGATGGTGACGGTTCGCCTCCG
TAGCTCAGTGGATAGAGCAC

Product: hydrolase

Products: NA

Alternate protein names: Tap [H]

Number of amino acids: Translated: 527; Mature: 526

Protein sequence:

>527_residues
MPRSTIKRVVAVLAASTALSPFLVSMPTAAAQENIRWEECPPQVDIASAQCGSIDVPMHYSDPSLGDISVGFVKVPAQGE
KHGTIFGNSGGPGGDAYSFFGSQSMNWPEAMYQNYDLVAVQPRGMVGSTPVNCDNIAPGYDFLSLLTREGAFVKESCEIG
TPGYTSSLTTDNTANDWERVRQALGDDKISIFGLSYGTYLGSVYATRYPQHTDKVVLDSAMAPSLAWNGIMASQEQGYKN
SLNDFFTWVAENNDTYGLGTTPLAVYQNWSNKIVAETGTNPTVAPPPAQVGDVPPAFAWAGQAGADMMTATNPTSVQLQG
LATQLLNPGSNQSLSPLLNVTRAYIPQPSTWPMLAGAISGQTPIPDVTDTGDDPYVIESINASVNMQRMVMCNENTVAPD
PVAMARMAWTSMVTGDVFDIYSVKFSSGQACSGITPTSGRQPTDGSQLAVQPLLLQGTSDPQTPYWTHNELADAMNAHVV
TVNGPGHGQSIGGTNQAINDIVVDYLRTGHTDATWVEGNTPTPITAG

Sequences:

>Translated_527_residues
MPRSTIKRVVAVLAASTALSPFLVSMPTAAAQENIRWEECPPQVDIASAQCGSIDVPMHYSDPSLGDISVGFVKVPAQGE
KHGTIFGNSGGPGGDAYSFFGSQSMNWPEAMYQNYDLVAVQPRGMVGSTPVNCDNIAPGYDFLSLLTREGAFVKESCEIG
TPGYTSSLTTDNTANDWERVRQALGDDKISIFGLSYGTYLGSVYATRYPQHTDKVVLDSAMAPSLAWNGIMASQEQGYKN
SLNDFFTWVAENNDTYGLGTTPLAVYQNWSNKIVAETGTNPTVAPPPAQVGDVPPAFAWAGQAGADMMTATNPTSVQLQG
LATQLLNPGSNQSLSPLLNVTRAYIPQPSTWPMLAGAISGQTPIPDVTDTGDDPYVIESINASVNMQRMVMCNENTVAPD
PVAMARMAWTSMVTGDVFDIYSVKFSSGQACSGITPTSGRQPTDGSQLAVQPLLLQGTSDPQTPYWTHNELADAMNAHVV
TVNGPGHGQSIGGTNQAINDIVVDYLRTGHTDATWVEGNTPTPITAG
>Mature_526_residues
PRSTIKRVVAVLAASTALSPFLVSMPTAAAQENIRWEECPPQVDIASAQCGSIDVPMHYSDPSLGDISVGFVKVPAQGEK
HGTIFGNSGGPGGDAYSFFGSQSMNWPEAMYQNYDLVAVQPRGMVGSTPVNCDNIAPGYDFLSLLTREGAFVKESCEIGT
PGYTSSLTTDNTANDWERVRQALGDDKISIFGLSYGTYLGSVYATRYPQHTDKVVLDSAMAPSLAWNGIMASQEQGYKNS
LNDFFTWVAENNDTYGLGTTPLAVYQNWSNKIVAETGTNPTVAPPPAQVGDVPPAFAWAGQAGADMMTATNPTSVQLQGL
ATQLLNPGSNQSLSPLLNVTRAYIPQPSTWPMLAGAISGQTPIPDVTDTGDDPYVIESINASVNMQRMVMCNENTVAPDP
VAMARMAWTSMVTGDVFDIYSVKFSSGQACSGITPTSGRQPTDGSQLAVQPLLLQGTSDPQTPYWTHNELADAMNAHVVT
VNGPGHGQSIGGTNQAINDIVVDYLRTGHTDATWVEGNTPTPITAG

Specific function: Cleaves tripeptides from the N-termini of proteins. Does not cleave mono- or dipeptides, or N-terminally blocked peptides [H]

COG id: COG0596

COG function: function code R; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S33 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013595 [H]

Pfam domain/function: PF08386 Abhydrolase_4 [H]

EC number: NA

Molecular weight: Translated: 55956; Mature: 55825

Theoretical pI: Translated: 4.18; Mature: 4.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRSTIKRVVAVLAASTALSPFLVSMPTAAAQENIRWEECPPQVDIASAQCGSIDVPMHY
CCHHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHCCCHHCCCCCCEECCCCCCCEECCEEC
SDPSLGDISVGFVKVPAQGEKHGTIFGNSGGPGGDAYSFFGSQSMNWPEAMYQNYDLVAV
CCCCCCCEEEEEEECCCCCCCCCEEEECCCCCCCCHHHHCCCCCCCCHHHHHCCCCEEEE
QPRGMVGSTPVNCDNIAPGYDFLSLLTREGAFVKESCEIGTPGYTSSLTTDNTANDWERV
CCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEECCCCCCCCCCCCCCCCCCCHHHHHHH
RQALGDDKISIFGLSYGTYLGSVYATRYPQHTDKVVLDSAMAPSLAWNGIMASQEQGYKN
HHHHCCCCEEEEEEEHHHHHHHHHHHCCCCCCCCEEHHHHCCCCHHHCCEECCCCCCCHH
SLNDFFTWVAENNDTYGLGTTPLAVYQNWSNKIVAETGTNPTVAPPPAQVGDVPPAFAWA
HHHHHEEEEECCCCEECCCCCCHHEEECCCCEEEEECCCCCCCCCCCCCCCCCCCHHHCC
GQAGADMMTATNPTSVQLQGLATQLLNPGSNQSLSPLLNVTRAYIPQPSTWPMLAGAISG
CCCCCCCEECCCCCCEEEHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHCCC
QTPIPDVTDTGDDPYVIESINASVNMQRMVMCNENTVAPDPVAMARMAWTSMVTGDVFDI
CCCCCCCCCCCCCCEEEEECCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCEEEE
YSVKFSSGQACSGITPTSGRQPTDGSQLAVQPLLLQGTSDPQTPYWTHNELADAMNAHVV
EEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCHHHHHHHHCCEEE
TVNGPGHGQSIGGTNQAINDIVVDYLRTGHTDATWVEGNTPTPITAG
EECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCC
>Mature Secondary Structure 
PRSTIKRVVAVLAASTALSPFLVSMPTAAAQENIRWEECPPQVDIASAQCGSIDVPMHY
CHHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHCCCHHCCCCCCEECCCCCCCEECCEEC
SDPSLGDISVGFVKVPAQGEKHGTIFGNSGGPGGDAYSFFGSQSMNWPEAMYQNYDLVAV
CCCCCCCEEEEEEECCCCCCCCCEEEECCCCCCCCHHHHCCCCCCCCHHHHHCCCCEEEE
QPRGMVGSTPVNCDNIAPGYDFLSLLTREGAFVKESCEIGTPGYTSSLTTDNTANDWERV
CCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEECCCCCCCCCCCCCCCCCCCHHHHHHH
RQALGDDKISIFGLSYGTYLGSVYATRYPQHTDKVVLDSAMAPSLAWNGIMASQEQGYKN
HHHHCCCCEEEEEEEHHHHHHHHHHHCCCCCCCCEEHHHHCCCCHHHCCEECCCCCCCHH
SLNDFFTWVAENNDTYGLGTTPLAVYQNWSNKIVAETGTNPTVAPPPAQVGDVPPAFAWA
HHHHHEEEEECCCCEECCCCCCHHEEECCCCEEEEECCCCCCCCCCCCCCCCCCCHHHCC
GQAGADMMTATNPTSVQLQGLATQLLNPGSNQSLSPLLNVTRAYIPQPSTWPMLAGAISG
CCCCCCCEECCCCCCEEEHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHCCC
QTPIPDVTDTGDDPYVIESINASVNMQRMVMCNENTVAPDPVAMARMAWTSMVTGDVFDI
CCCCCCCCCCCCCCEEEEECCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCEEEE
YSVKFSSGQACSGITPTSGRQPTDGSQLAVQPLLLQGTSDPQTPYWTHNELADAMNAHVV
EEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCHHHHHHHHCCEEE
TVNGPGHGQSIGGTNQAINDIVVDYLRTGHTDATWVEGNTPTPITAG
EECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]