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The map label for this gene is nadA [H]

Identifier: 62389958

GI number: 62389958

Start: 1119217

End: 1120503

Strand: Reverse

Name: nadA [H]

Synonym: cg1216

Alternate gene names: 62389958

Gene position: 1120503-1119217 (Counterclockwise)

Preceding gene: 62389959

Following gene: 62389957

Centisome position: 34.13

GC content: 55.17

Gene sequence:

>1287_bases
ATGACCACCTCAATCACCCCATCTGTCAACCTTGCATTGAAAAATGCCAATAGCTGCAACAGTGAACTCAAAGACGGACC
CTGGTTCCTCGACCAGCCCGGAATGCCGGATGTCTACGGCCCCGGCGCGTCACAAAACGATCCGATCCCTGCGCATGCTC
CGCGCCAGCAGGTTCTCCCCGAGGAGTACCAGCGCGCAAGTGATGACGAACTGCATCGTAGGATCCGGGAAGCGAAAGAC
ACCCTGGGTGACAAAGTGGTTATCCTAGGACACTTCTACCAGCGCGATGAAGTTATCCAACACGCAGATTTTGTTGGTGA
CTCTTTCCAACTTGCCCGCGCTGCCAAAACCCGACCCGAGGCGGAAGCGATTGTGTTCTGCGGTGTGCACTTCATGGCTG
AAACCGCTGATCTGTTATCCACGGATGAACAATCAGTGATCCTCCCCAACCTTGCCGCAGGTTGCTCCATGGCAGACATG
GCTGACCTTGATTCCGTCGAAGACTGCTGGGAGCAACTCACCTCAATTTATGGCGATGACACCCTGATCCCTGTGACCTA
CATGAATTCCTCTGCAGCGCTCAAAGGTTTCGTGGGTGAGCACGGCGGAATTGTATGCACCTCCTCAAATGCACGTTCCG
TATTGGAGTGGGCGTTTGAACGCGGCCAACGAGTCCTGTTCTTCCCCGATCAGCACTTGGGTCGAAACACCGCGAAAGCC
ATGGGCATTGGGATCGATCAAATGCCCCTGTGGAATCCCAACAAACCACTGGGTGGCAACACCGTTTCCGAGCTAGAAAA
CGCAAAGGTACTGCTCTGGCATGGTTTCTGCTCTGTACACAAGCGCTTTACTGTCGAGCAGATCAACAAAGCCCGCGCCG
AGTACCCCGACGTTCACGTCATCGTGCACCCTGAATCCCCCATGCCAGTTGTTGACGCCGCCGACTCATCCGGATCCACT
GACTTCATTGTGAAAGCCATTCAAGCAGCACCGGCAGGATCTACCTTTGCGATCGGCACCGAAATCAACTTGGTTCAGCG
CCTGGCAGCCCAGTACCCGCAGCACACCATCTTCTGCCTCGACCCTGTCATCTGCCCATGCTCCACCATGTATCGCATTC
ACCCTGGTTACCTGGCCTGGGCACTTGAGGAGTTGGTGGCTGGAAACGTGATTAACCAGATTTCTGTCTCTGAATCCGTG
GCGGCACCGGCGCGAGTCGCTTTGGAAAGGATGCTATCTGTTGTTCCAGCAGCTCCTGTTACTCCTAGCTCCTCGAAGGA
TGCGTAA

Upstream 100 bases:

>100_bases
GCTTGCGGGAACACCGCACCGCCCACCCAAACTGTTCAGATTCCAAAGATAAATTCTGACGCTCATTCCAGCCCACCGTT
TAGAAGAAAAGACCCCAATC

Downstream 100 bases:

>100_bases
TTTATGACTACCCATATTGACCGCATCGTTGGCGCAGCGTTATCCGAGGATGCGCCATGGGGCGACATTACCTCCGACAC
TTTTATCCCAGGATCGGCGC

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 428; Mature: 427

Protein sequence:

>428_residues
MTTSITPSVNLALKNANSCNSELKDGPWFLDQPGMPDVYGPGASQNDPIPAHAPRQQVLPEEYQRASDDELHRRIREAKD
TLGDKVVILGHFYQRDEVIQHADFVGDSFQLARAAKTRPEAEAIVFCGVHFMAETADLLSTDEQSVILPNLAAGCSMADM
ADLDSVEDCWEQLTSIYGDDTLIPVTYMNSSAALKGFVGEHGGIVCTSSNARSVLEWAFERGQRVLFFPDQHLGRNTAKA
MGIGIDQMPLWNPNKPLGGNTVSELENAKVLLWHGFCSVHKRFTVEQINKARAEYPDVHVIVHPESPMPVVDAADSSGST
DFIVKAIQAAPAGSTFAIGTEINLVQRLAAQYPQHTIFCLDPVICPCSTMYRIHPGYLAWALEELVAGNVINQISVSESV
AAPARVALERMLSVVPAAPVTPSSSKDA

Sequences:

>Translated_428_residues
MTTSITPSVNLALKNANSCNSELKDGPWFLDQPGMPDVYGPGASQNDPIPAHAPRQQVLPEEYQRASDDELHRRIREAKD
TLGDKVVILGHFYQRDEVIQHADFVGDSFQLARAAKTRPEAEAIVFCGVHFMAETADLLSTDEQSVILPNLAAGCSMADM
ADLDSVEDCWEQLTSIYGDDTLIPVTYMNSSAALKGFVGEHGGIVCTSSNARSVLEWAFERGQRVLFFPDQHLGRNTAKA
MGIGIDQMPLWNPNKPLGGNTVSELENAKVLLWHGFCSVHKRFTVEQINKARAEYPDVHVIVHPESPMPVVDAADSSGST
DFIVKAIQAAPAGSTFAIGTEINLVQRLAAQYPQHTIFCLDPVICPCSTMYRIHPGYLAWALEELVAGNVINQISVSESV
AAPARVALERMLSVVPAAPVTPSSSKDA
>Mature_427_residues
TTSITPSVNLALKNANSCNSELKDGPWFLDQPGMPDVYGPGASQNDPIPAHAPRQQVLPEEYQRASDDELHRRIREAKDT
LGDKVVILGHFYQRDEVIQHADFVGDSFQLARAAKTRPEAEAIVFCGVHFMAETADLLSTDEQSVILPNLAAGCSMADMA
DLDSVEDCWEQLTSIYGDDTLIPVTYMNSSAALKGFVGEHGGIVCTSSNARSVLEWAFERGQRVLFFPDQHLGRNTAKAM
GIGIDQMPLWNPNKPLGGNTVSELENAKVLLWHGFCSVHKRFTVEQINKARAEYPDVHVIVHPESPMPVVDAADSSGSTD
FIVKAIQAAPAGSTFAIGTEINLVQRLAAQYPQHTIFCLDPVICPCSTMYRIHPGYLAWALEELVAGNVINQISVSESVA
APARVALERMLSVVPAAPVTPSSSKDA

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 3 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=340, Percent_Identity=28.5294117647059, Blast_Score=124, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 46508; Mature: 46377

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTSITPSVNLALKNANSCNSELKDGPWFLDQPGMPDVYGPGASQNDPIPAHAPRQQVLP
CCCCCCCCEEEEEECCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCHHHCCC
EEYQRASDDELHRRIREAKDTLGDKVVILGHFYQRDEVIQHADFVGDSFQLARAAKTRPE
HHHHCCCHHHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHCCCHHHHHHHHCCCCC
AEAIVFCGVHFMAETADLLSTDEQSVILPNLAAGCSMADMADLDSVEDCWEQLTSIYGDD
CCEEEEECHHHHHHHHHHHCCCCCCEECCCHHCCCCCHHHHCCCHHHHHHHHHHHHCCCC
TLIPVTYMNSSAALKGFVGEHGGIVCTSSNARSVLEWAFERGQRVLFFPDQHLGRNTAKA
CEEEEEEECCCHHHHHHHCCCCCEEEECCCHHHHHHHHHHCCCEEEECCCHHCCCHHHHH
MGIGIDQMPLWNPNKPLGGNTVSELENAKVLLWHGFCSVHKRFTVEQINKARAEYPDVHV
HCCCCCCCCCCCCCCCCCCCHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHHCCCCCEEE
IVHPESPMPVVDAADSSGSTDFIVKAIQAAPAGSTFAIGTEINLVQRLAAQYPQHTIFCL
EECCCCCCCEEECCCCCCCHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHCCCCEEEEE
DPVICPCSTMYRIHPGYLAWALEELVAGNVINQISVSESVAAPARVALERMLSVVPAAPV
CCCCCCCCCCEEECCHHHHHHHHHHHHCCHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCC
TPSSSKDA
CCCCCCCC
>Mature Secondary Structure 
TTSITPSVNLALKNANSCNSELKDGPWFLDQPGMPDVYGPGASQNDPIPAHAPRQQVLP
CCCCCCCEEEEEECCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCHHHCCC
EEYQRASDDELHRRIREAKDTLGDKVVILGHFYQRDEVIQHADFVGDSFQLARAAKTRPE
HHHHCCCHHHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHCCCHHHHHHHHCCCCC
AEAIVFCGVHFMAETADLLSTDEQSVILPNLAAGCSMADMADLDSVEDCWEQLTSIYGDD
CCEEEEECHHHHHHHHHHHCCCCCCEECCCHHCCCCCHHHHCCCHHHHHHHHHHHHCCCC
TLIPVTYMNSSAALKGFVGEHGGIVCTSSNARSVLEWAFERGQRVLFFPDQHLGRNTAKA
CEEEEEEECCCHHHHHHHCCCCCEEEECCCHHHHHHHHHHCCCEEEECCCHHCCCHHHHH
MGIGIDQMPLWNPNKPLGGNTVSELENAKVLLWHGFCSVHKRFTVEQINKARAEYPDVHV
HCCCCCCCCCCCCCCCCCCCHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHHCCCCCEEE
IVHPESPMPVVDAADSSGSTDFIVKAIQAAPAGSTFAIGTEINLVQRLAAQYPQHTIFCL
EECCCCCCCEEECCCCCCCHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHCCCCEEEEE
DPVICPCSTMYRIHPGYLAWALEELVAGNVINQISVSESVAAPARVALERMLSVVPAAPV
CCCCCCCCCCEEECCHHHHHHHHHHHHCCHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCC
TPSSSKDA
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12948626 [H]