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The map label for this gene is alsT [H]

Identifier: 62389103

GI number: 62389103

Start: 222208

End: 223695

Strand: Reverse

Name: alsT [H]

Synonym: cg0254

Alternate gene names: 62389103

Gene position: 223695-222208 (Counterclockwise)

Preceding gene: 62389104

Following gene: 62389101

Centisome position: 6.81

GC content: 53.09

Gene sequence:

>1488_bases
ATGGAATTATTGGAGACCTTCATCACTGATGTCATTAATGACAATTTGTGGATGATCTTGCCCTTCTTGCTCGTTGCTGC
TGGCCTCTATTTCGGTGGGCGTACGTTGCTGGTTCAGATTCGGATGATTCCGGAGATGTTCAAAGCGGTCGTCGAGAAGC
CTGCGAAGGATGGGGAGTTCGCGGACAAGCAGGACATTTCGGCTTTTAAGGCGTTCACGATTTCTGCGGCGTCGCGAGTT
GGTACGGCGAATGTTGCGGGTGTTGCGCTGGCGATCACTCTGGGTGGACCGGGTGCAGTGTTCTGGATGTGGATCATTGC
GCTGGTTGGCGGTGCGACATCGTTCATTGAGTCGACTCTTGGACAGTTGTGGAAGGTGAAGGACGGCGACAGCTATCGCG
GTGGCCCTGCGTACTACATGACGCTTGGTTTGAATGCTCGGTGGCTTGCGGTTGTTTTCGGTGTCGCCATCACGTTGACC
TTTGGTTTTGTGTACAACGCTTTGCAGTCCAACGCGGTTGTTGAGGCGATTACGGTATCACTCGGCACCCCTTCTACCAC
TGCAAAGGCTTTTGTTGGCTTGGGCATGGCTGGATTGTCTGCGCTGGTTATTTTTGGCGGCGTGCAGCGTATCGCAAACG
TGACGCAGTGGATGGTTCCGTTCATGGCGGGTGCGTACATCATTGTGGGTGTGGTGGTGATTGTGATTAACATTCAGCAG
GTTCCGACCATGATCAACGACATCATTGCTGGTGCTTTTGGTTTCCGTCCGGTTGCTACTGCGTCGGTGTGGGGCGCGTT
CTGGTTGGCGTTTATGAACGGTATGCGCCGTGGACTGTTCTCCAATGAGGCTGGTGAGGGTTCTGTCCCGAACGCTGCTG
CTACCGCGACTGTGTCTCACCCTGTGAAGCAGGGTTTGGTTCAGACTCTGGGCGTATATTTCGACACCCTGCTCGTTTGT
AGCATTACCGCTTTTGTCATCCTGCTGTCTGGAGTGGAGTACGCGACCGGCGATATTCAGTCTTCTTCTTTGACTCAGTC
CGCGCTGGCTAGCGTTGTTGGTGGTTGGGGAACCCACTTCATTACCGTAGTGATGTTCTTCCTGGCGTTTTCTTCCGTGC
TGGGTAACTACTACTTGGCACAGGCGAATATTCAGTACTTCACCGATTCGAAGACTGTCATGACTGTTTTCCGACTCTTG
GTGCTGCTCAGCGTGTTCTCTGGCGCGGTTGCTTCGGTGCCGTTGATCTGGGCTTTGGGTGATACTTTCGCTGGCATCAT
GGTGCTCATTAACCTGGCGGCGATCATTCCGCTGGGTGGCGTTGCAGTGAAGTTGCTTAAGAATTACACCATTCAGAAGA
AGGCTGGTCTGGATCCTGTGTTCCACCGCGACATGATGCCAGAGGTTCGTAATATTGCGTGCTGGAACGGCAAAGATGCA
GCTACATCCAACTATCACGAAGCGATGGAAGTGATCAAGAAGAGCTAG

Upstream 100 bases:

>100_bases
AGCTAATCTGCCTTGCTTTACACCTCCGGGCTATAACAATCCAGTGCCAGTGGCTAGGGATTTACTAAAAATCGGGTAAC
ACGCGCGTAGTATTTTTCGC

Downstream 100 bases:

>100_bases
TCATCGAAGGAACAGTGGTATGGCCCGTCAGCGTCTCGGATTGTCTGGCAGGCCAACACTTGGTTTTCGGAGACGATCTC
GTAGTTGCTCAGTACTTCAT

Product: amino acid carrier protein (sodium/alanine symporter)

Products: Na (I) [Cytoplasm]; L-alanine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 495; Mature: 495

Protein sequence:

>495_residues
MELLETFITDVINDNLWMILPFLLVAAGLYFGGRTLLVQIRMIPEMFKAVVEKPAKDGEFADKQDISAFKAFTISAASRV
GTANVAGVALAITLGGPGAVFWMWIIALVGGATSFIESTLGQLWKVKDGDSYRGGPAYYMTLGLNARWLAVVFGVAITLT
FGFVYNALQSNAVVEAITVSLGTPSTTAKAFVGLGMAGLSALVIFGGVQRIANVTQWMVPFMAGAYIIVGVVVIVINIQQ
VPTMINDIIAGAFGFRPVATASVWGAFWLAFMNGMRRGLFSNEAGEGSVPNAAATATVSHPVKQGLVQTLGVYFDTLLVC
SITAFVILLSGVEYATGDIQSSSLTQSALASVVGGWGTHFITVVMFFLAFSSVLGNYYLAQANIQYFTDSKTVMTVFRLL
VLLSVFSGAVASVPLIWALGDTFAGIMVLINLAAIIPLGGVAVKLLKNYTIQKKAGLDPVFHRDMMPEVRNIACWNGKDA
ATSNYHEAMEVIKKS

Sequences:

>Translated_495_residues
MELLETFITDVINDNLWMILPFLLVAAGLYFGGRTLLVQIRMIPEMFKAVVEKPAKDGEFADKQDISAFKAFTISAASRV
GTANVAGVALAITLGGPGAVFWMWIIALVGGATSFIESTLGQLWKVKDGDSYRGGPAYYMTLGLNARWLAVVFGVAITLT
FGFVYNALQSNAVVEAITVSLGTPSTTAKAFVGLGMAGLSALVIFGGVQRIANVTQWMVPFMAGAYIIVGVVVIVINIQQ
VPTMINDIIAGAFGFRPVATASVWGAFWLAFMNGMRRGLFSNEAGEGSVPNAAATATVSHPVKQGLVQTLGVYFDTLLVC
SITAFVILLSGVEYATGDIQSSSLTQSALASVVGGWGTHFITVVMFFLAFSSVLGNYYLAQANIQYFTDSKTVMTVFRLL
VLLSVFSGAVASVPLIWALGDTFAGIMVLINLAAIIPLGGVAVKLLKNYTIQKKAGLDPVFHRDMMPEVRNIACWNGKDA
ATSNYHEAMEVIKKS
>Mature_495_residues
MELLETFITDVINDNLWMILPFLLVAAGLYFGGRTLLVQIRMIPEMFKAVVEKPAKDGEFADKQDISAFKAFTISAASRV
GTANVAGVALAITLGGPGAVFWMWIIALVGGATSFIESTLGQLWKVKDGDSYRGGPAYYMTLGLNARWLAVVFGVAITLT
FGFVYNALQSNAVVEAITVSLGTPSTTAKAFVGLGMAGLSALVIFGGVQRIANVTQWMVPFMAGAYIIVGVVVIVINIQQ
VPTMINDIIAGAFGFRPVATASVWGAFWLAFMNGMRRGLFSNEAGEGSVPNAAATATVSHPVKQGLVQTLGVYFDTLLVC
SITAFVILLSGVEYATGDIQSSSLTQSALASVVGGWGTHFITVVMFFLAFSSVLGNYYLAQANIQYFTDSKTVMTVFRLL
VLLSVFSGAVASVPLIWALGDTFAGIMVLINLAAIIPLGGVAVKLLKNYTIQKKAGLDPVFHRDMMPEVRNIACWNGKDA
ATSNYHEAMEVIKKS

Specific function: Unknown

COG id: COG1115

COG function: function code E; Na+/alanine symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:alanine (SAF) symporter family [H]

Homologues:

Organism=Escherichia coli, GI1786188, Length=463, Percent_Identity=36.9330453563715, Blast_Score=285, Evalue=5e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001463 [H]

Pfam domain/function: PF01235 Na_Ala_symp [H]

EC number: NA

Molecular weight: Translated: 52794; Mature: 52794

Theoretical pI: Translated: 8.16; Mature: 8.16

Prosite motif: PS00873 NA_ALANINE_SYMP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELLETFITDVINDNLWMILPFLLVAAGLYFGGRTLLVQIRMIPEMFKAVVEKPAKDGEF
CHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCC
ADKQDISAFKAFTISAASRVGTANVAGVALAITLGGPGAVFWMWIIALVGGATSFIESTL
CCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHHHHCCHHHHHHHHH
GQLWKVKDGDSYRGGPAYYMTLGLNARWLAVVFGVAITLTFGFVYNALQSNAVVEAITVS
HHHEECCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHEEE
LGTPSTTAKAFVGLGMAGLSALVIFGGVQRIANVTQWMVPFMAGAYIIVGVVVIVINIQQ
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VPTMINDIIAGAFGFRPVATASVWGAFWLAFMNGMRRGLFSNEAGEGSVPNAAATATVSH
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHH
PVKQGLVQTLGVYFDTLLVCSITAFVILLSGVEYATGDIQSSSLTQSALASVVGGWGTHF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCHHHHHHHHHHHHHCCHHHHH
ITVVMFFLAFSSVLGNYYLAQANIQYFTDSKTVMTVFRLLVLLSVFSGAVASVPLIWALG
HHHHHHHHHHHHHHCCCEEEECCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DTFAGIMVLINLAAIIPLGGVAVKLLKNYTIQKKAGLDPVFHRDMMPEVRNIACWNGKDA
HHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHCCCCHHHHHHHCHHHHCEECCCCCCC
ATSNYHEAMEVIKKS
CCCHHHHHHHHHHCC
>Mature Secondary Structure
MELLETFITDVINDNLWMILPFLLVAAGLYFGGRTLLVQIRMIPEMFKAVVEKPAKDGEF
CHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCC
ADKQDISAFKAFTISAASRVGTANVAGVALAITLGGPGAVFWMWIIALVGGATSFIESTL
CCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHHHHCCHHHHHHHHH
GQLWKVKDGDSYRGGPAYYMTLGLNARWLAVVFGVAITLTFGFVYNALQSNAVVEAITVS
HHHEECCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHEEE
LGTPSTTAKAFVGLGMAGLSALVIFGGVQRIANVTQWMVPFMAGAYIIVGVVVIVINIQQ
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VPTMINDIIAGAFGFRPVATASVWGAFWLAFMNGMRRGLFSNEAGEGSVPNAAATATVSH
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHH
PVKQGLVQTLGVYFDTLLVCSITAFVILLSGVEYATGDIQSSSLTQSALASVVGGWGTHF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCHHHHHHHHHHHHHCCHHHHH
ITVVMFFLAFSSVLGNYYLAQANIQYFTDSKTVMTVFRLLVLLSVFSGAVASVPLIWALG
HHHHHHHHHHHHHHCCCEEEECCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DTFAGIMVLINLAAIIPLGGVAVKLLKNYTIQKKAGLDPVFHRDMMPEVRNIACWNGKDA
HHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHCCCCHHHHHHHCHHHHCEECCCCCCC
ATSNYHEAMEVIKKS
CCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; L-alanine [Periplasm] [C]

Specific reaction: Na (I) [Periplasm] + L-alanine [Periplasm] = Na (I) [Cytoplasm] + L-alanine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969507; 9384377; 7710280 [H]