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The map label for this gene is ilvG [C]

Identifier: 62388992

GI number: 62388992

Start: 105839

End: 106393

Strand: Reverse

Name: ilvG [C]

Synonym: cg0127

Alternate gene names: 62388992

Gene position: 106393-105839 (Counterclockwise)

Preceding gene: 62388993

Following gene: 62388991

Centisome position: 3.24

GC content: 58.92

Gene sequence:

>555_bases
GTGTACTCAATTTCAGAAACTATCGCCCGAACTCTTATGCCCCGCACCGATCACGTTTTCGACCTGATGGGCAACGGAAA
CGCCTGGTTCGTCGATGCCCTAGAACGCCTCGGGCGAGGCATCATCACCGTCCGCCCCACAGTTGAAACCGTGGCCGCCG
CGGACACCTACCACCGCGTCACCCGCCGCCCGGCGGTCGCTACCACCACCTATGGTGCTGGTTTCACCAACACCATGACC
ACGCTTGCCGACGTCGCCCTCTCCCGTATCCCACTTCTTTTAGTTGTGGGCACTGCCCCGAGCGCCGGGCCTCGCTGTTT
CGACATTGACCGGCAAGGACTCGCACGTGCCGTAGGTGTGGAAACCTTCACCGTGCATGCAGATGACGTTGCTGCGGTAA
CTCTTCAGGCTTGGAATAATACGCCGGAAAACACACACGTGATCCTGGAAATCCCCTATGACCTAGCAGCTGCCACAGCC
ACCGATCCAACAGTGACTACATACCTGCTGCGCCCCGGATTTCAGAAACTCCCGATGTCACCGACCTTGTCCTAG

Upstream 100 bases:

>100_bases
TTGAAAAAGGAACATTAGTGCCAGTAACAAGAGCCCAGTTGAATTCAAGCGGGCAGAGACACATCTGGCCCTCAAAATTT
TCCTTTTACTGGAGACCACT

Downstream 100 bases:

>100_bases
CTCTACGCAATGCCCAAAATCCCCTCCCTCTTGCAGGTCGTGGCACACGCGAAGCACAGCAAAGCATCCTGGAATTAGCA
GATCTTTTGGCAGCTGATGT

Product: thiamine pyrophosphate dependent enzyme

Products: succinate; glyoxylate

Alternate protein names: Thiamine Pyrophosphate-Requiring

Number of amino acids: Translated: 184; Mature: 184

Protein sequence:

>184_residues
MYSISETIARTLMPRTDHVFDLMGNGNAWFVDALERLGRGIITVRPTVETVAAADTYHRVTRRPAVATTTYGAGFTNTMT
TLADVALSRIPLLLVVGTAPSAGPRCFDIDRQGLARAVGVETFTVHADDVAAVTLQAWNNTPENTHVILEIPYDLAAATA
TDPTVTTYLLRPGFQKLPMSPTLS

Sequences:

>Translated_184_residues
MYSISETIARTLMPRTDHVFDLMGNGNAWFVDALERLGRGIITVRPTVETVAAADTYHRVTRRPAVATTTYGAGFTNTMT
TLADVALSRIPLLLVVGTAPSAGPRCFDIDRQGLARAVGVETFTVHADDVAAVTLQAWNNTPENTHVILEIPYDLAAATA
TDPTVTTYLLRPGFQKLPMSPTLS
>Mature_184_residues
MYSISETIARTLMPRTDHVFDLMGNGNAWFVDALERLGRGIITVRPTVETVAAADTYHRVTRRPAVATTTYGAGFTNTMT
TLADVALSRIPLLLVVGTAPSAGPRCFDIDRQGLARAVGVETFTVHADDVAAVTLQAWNNTPENTHVILEIPYDLAAATA
TDPTVTTYLLRPGFQKLPMSPTLS

Specific function: Valine and isoleucine biosynthesis; first step. [C]

COG id: COG0028

COG function: function code EH; Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 4.1.3.1

Molecular weight: Translated: 19860; Mature: 19860

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYSISETIARTLMPRTDHVFDLMGNGNAWFVDALERLGRGIITVRPTVETVAAADTYHRV
CCCHHHHHHHHHCCCCCCEEEEECCCCEEHHHHHHHHCCCEEEECCCHHHHHHHHHHHHH
TRRPAVATTTYGAGFTNTMTTLADVALSRIPLLLVVGTAPSAGPRCFDIDRQGLARAVGV
HCCCCEEEEECCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCEEEECCHHHHHHHHCC
ETFTVHADDVAAVTLQAWNNTPENTHVILEIPYDLAAATATDPTVTTYLLRPGFQKLPMS
EEEEEECCCEEEEEEEECCCCCCCCEEEEEECCCCEECCCCCCCEEEEEECCCHHHCCCC
PTLS
CCCC
>Mature Secondary Structure
MYSISETIARTLMPRTDHVFDLMGNGNAWFVDALERLGRGIITVRPTVETVAAADTYHRV
CCCHHHHHHHHHCCCCCCEEEEECCCCEEHHHHHHHHCCCEEEECCCHHHHHHHHHHHHH
TRRPAVATTTYGAGFTNTMTTLADVALSRIPLLLVVGTAPSAGPRCFDIDRQGLARAVGV
HCCCCEEEEECCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCEEEECCHHHHHHHHCC
ETFTVHADDVAAVTLQAWNNTPENTHVILEIPYDLAAATATDPTVTTYLLRPGFQKLPMS
EEEEEECCCEEEEEEEECCCCCCCCEEEEEECCCCEECCCCCCCEEEEEECCCHHHCCCC
PTLS
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: isocitrate

Specific reaction: isocitrate = succinate + glyoxylate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA