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The map label for this gene is corA [H]

Identifier: 62388956

GI number: 62388956

Start: 62387

End: 63508

Strand: Reverse

Name: corA [H]

Synonym: cg0080

Alternate gene names: 62388956

Gene position: 63508-62387 (Counterclockwise)

Preceding gene: 62388957

Following gene: 62388950

Centisome position: 1.93

GC content: 56.51

Gene sequence:

>1122_bases
ATGCCAAAGAATTACGACATCAACGGGGCGATCCGCAGACGGGATATGCTCAGACGTCGGTACCTTCCTGATTCGGCAAA
TTCAACTCCTGTACCTGAAGAGGTTTCTCCGCTGACCCGCTATGTCACCGACGGCATCCCGAAGCGCCCACCGCTGGGTG
CCACTGTTGCTGACGGTTTAAAATTCGCCGAAGGCGCCTCCAACCGCATGGTCATGTCGCTGTACCCTGCGCCATCCAAG
CCCGCAATCGAGGAATTGGCAGAGGCCTGGGACCTCCACCCCACCATCGTAGAAGACTTGCTCCTTGGTCAGCAGCGCCC
AAAACTAGACCGCTACGAAGACATCATTTTTATCGCGATCCGCTCCGCGCGCTACATCGACTCCCGCGAAGAGGTGGACT
TCTCCGAATTCCACATCCTCATGAAGCCTCAGGCCATAGCCATTTTGTGCCAGGATAACCAATGGATTGACGGCACCAGC
GCCGCCAGCTTCAGCAACCCCGAGGAGATCGATAAGCGCATAAAAACATTGCTTGCCGACGCCGAGTTACTCTCGTCCGG
CCCCCGCGCCGTGGCCTATAGGCTTGTCGACGCCATCGTCGACGGCTTCTCCCCCGTTCTTAGAGGCATCGCCATCGACC
AGGAACAGATTGAGCGCCAGGTGTTCTCCGGCGACGCCGCCGTCGCCGAACGTATTTACAACCTGTCCCAAGAAATCATC
GACATGCAGCACACCACCAGCTCAGTTACCGAAGTGGTGCAACGCCTCAACAAAGACTTCATCCGAAGTGGCATGTCCGA
AGAACTCCGCGCCTACCTCGACGACGTCGCCGACCACCTCACCCGCGACAACACCCGCGTCTCCGAATACCGCGAATCCC
TATCCCAAATTTTGAACGTCAACGCCACCCTTGTAGCCCAACGCCAAAACGAAGACATGAAGAAAATCTCCGGATGGGCC
GCCATCATCTTCGCCCCAACCCTCGTGTCCTCCATCTACGGCATGAACTTCGACATCATGCCAGAACTTCACTGGGCGTT
TGGCTACCCGTTGGCTCTCTTAGCAATGCTCGGATTCACCCTCCTTTTGTACTGGATCTTCAAACGCAGTAAGTGGATGT
GA

Upstream 100 bases:

>100_bases
GAAGGATCGTCAGAATAGCTCTCGAATAGGCCATTTCTTACTTCATCGGCAATACTGACTTAGTAGAAATTGCTGTCCAG
AACTGTTGAAGGAGTTGAAA

Downstream 100 bases:

>100_bases
GACAAAAACCGAAAAACCAACAGGCCTCGGAAATTCCAGGGCTTGTTGGTTTTCTAGTTTGATCACTCTTGCAAAGCAGC
CAACGCTTCTGTGCGGGCAG

Product: CorA-like Mg2+ transporter protein

Products: Ni2; [Cytoplasm]; Co; 2 [Cytoplasm]; Mg (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 373; Mature: 372

Protein sequence:

>373_residues
MPKNYDINGAIRRRDMLRRRYLPDSANSTPVPEEVSPLTRYVTDGIPKRPPLGATVADGLKFAEGASNRMVMSLYPAPSK
PAIEELAEAWDLHPTIVEDLLLGQQRPKLDRYEDIIFIAIRSARYIDSREEVDFSEFHILMKPQAIAILCQDNQWIDGTS
AASFSNPEEIDKRIKTLLADAELLSSGPRAVAYRLVDAIVDGFSPVLRGIAIDQEQIERQVFSGDAAVAERIYNLSQEII
DMQHTTSSVTEVVQRLNKDFIRSGMSEELRAYLDDVADHLTRDNTRVSEYRESLSQILNVNATLVAQRQNEDMKKISGWA
AIIFAPTLVSSIYGMNFDIMPELHWAFGYPLALLAMLGFTLLLYWIFKRSKWM

Sequences:

>Translated_373_residues
MPKNYDINGAIRRRDMLRRRYLPDSANSTPVPEEVSPLTRYVTDGIPKRPPLGATVADGLKFAEGASNRMVMSLYPAPSK
PAIEELAEAWDLHPTIVEDLLLGQQRPKLDRYEDIIFIAIRSARYIDSREEVDFSEFHILMKPQAIAILCQDNQWIDGTS
AASFSNPEEIDKRIKTLLADAELLSSGPRAVAYRLVDAIVDGFSPVLRGIAIDQEQIERQVFSGDAAVAERIYNLSQEII
DMQHTTSSVTEVVQRLNKDFIRSGMSEELRAYLDDVADHLTRDNTRVSEYRESLSQILNVNATLVAQRQNEDMKKISGWA
AIIFAPTLVSSIYGMNFDIMPELHWAFGYPLALLAMLGFTLLLYWIFKRSKWM
>Mature_372_residues
PKNYDINGAIRRRDMLRRRYLPDSANSTPVPEEVSPLTRYVTDGIPKRPPLGATVADGLKFAEGASNRMVMSLYPAPSKP
AIEELAEAWDLHPTIVEDLLLGQQRPKLDRYEDIIFIAIRSARYIDSREEVDFSEFHILMKPQAIAILCQDNQWIDGTSA
ASFSNPEEIDKRIKTLLADAELLSSGPRAVAYRLVDAIVDGFSPVLRGIAIDQEQIERQVFSGDAAVAERIYNLSQEIID
MQHTTSSVTEVVQRLNKDFIRSGMSEELRAYLDDVADHLTRDNTRVSEYRESLSQILNVNATLVAQRQNEDMKKISGWAA
IIFAPTLVSSIYGMNFDIMPELHWAFGYPLALLAMLGFTLLLYWIFKRSKWM

Specific function: Mediates influx of magnesium ions [H]

COG id: COG0598

COG function: function code P; Mg2+ and Co2+ transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family [H]

Homologues:

Organism=Escherichia coli, GI2367297, Length=101, Percent_Identity=38.6138613861386, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004488
- InterPro:   IPR002523 [H]

Pfam domain/function: PF01544 CorA [H]

EC number: NA

Molecular weight: Translated: 42260; Mature: 42129

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKNYDINGAIRRRDMLRRRYLPDSANSTPVPEEVSPLTRYVTDGIPKRPPLGATVADGL
CCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHH
KFAEGASNRMVMSLYPAPSKPAIEELAEAWDLHPTIVEDLLLGQQRPKLDRYEDIIFIAI
HHHCCCCCCEEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCCCCHHHHCEEEEEE
RSARYIDSREEVDFSEFHILMKPQAIAILCQDNQWIDGTSAASFSNPEEIDKRIKTLLAD
HHHHHCCCCCCCCHHHHEEEECCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
AELLSSGPRAVAYRLVDAIVDGFSPVLRGIAIDQEQIERQVFSGDAAVAERIYNLSQEII
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHH
DMQHTTSSVTEVVQRLNKDFIRSGMSEELRAYLDDVADHLTRDNTRVSEYRESLSQILNV
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCC
NATLVAQRQNEDMKKISGWAAIIFAPTLVSSIYGMNFDIMPELHWAFGYPLALLAMLGFT
CHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCHHHHHHHHHHH
LLLYWIFKRSKWM
HHHHHHHHHCCCC
>Mature Secondary Structure 
PKNYDINGAIRRRDMLRRRYLPDSANSTPVPEEVSPLTRYVTDGIPKRPPLGATVADGL
CCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHH
KFAEGASNRMVMSLYPAPSKPAIEELAEAWDLHPTIVEDLLLGQQRPKLDRYEDIIFIAI
HHHCCCCCCEEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCCCCHHHHCEEEEEE
RSARYIDSREEVDFSEFHILMKPQAIAILCQDNQWIDGTSAASFSNPEEIDKRIKTLLAD
HHHHHCCCCCCCCHHHHEEEECCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
AELLSSGPRAVAYRLVDAIVDGFSPVLRGIAIDQEQIERQVFSGDAAVAERIYNLSQEII
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHH
DMQHTTSSVTEVVQRLNKDFIRSGMSEELRAYLDDVADHLTRDNTRVSEYRESLSQILNV
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCC
NATLVAQRQNEDMKKISGWAAIIFAPTLVSSIYGMNFDIMPELHWAFGYPLALLAMLGFT
CHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCHHHHHHHHHHH
LLLYWIFKRSKWM
HHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; Co; 2 [Periplasm]; Mg (II) [Periplasm] [C]

Specific reaction: Ni2+ [Periplasm] = Ni2+ [Cytoplasm] Co+2 [Periplasm] = Co+2 [Cytoplasm] Mg (II) [Periplasm] = Mg (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]