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The map label for this gene is yebK [H]

Identifier: 59711498

GI number: 59711498

Start: 980067

End: 980924

Strand: Reverse

Name: yebK [H]

Synonym: VF_0891

Alternate gene names: 59711498

Gene position: 980924-980067 (Counterclockwise)

Preceding gene: 59711499

Following gene: 59711497

Centisome position: 33.85

GC content: 39.98

Gene sequence:

>858_bases
ATGAATACCATTGAGAAAATACAAAATAATTTAGATAACTTCAGCAAATCAGAGCGCAAAGTAGCTGAAGTAATTATGGC
CTCACCTCAAACAGCAATTCATTCAAGTATTGCCACTTTAGCTAAAATGGCTGACGTTAGTGAGCCAACGGTAAACCGTT
TTTGCCGTCGACTAGATACAAAAGGCTTCCCAGACTTTAAACTTCATCTTGCACAAAGCCTTGCCAATGGTACTCCTTAT
GTAAACCGTAATGTTGAAGAAAACGATGGTCCAGATGCATACACACATAAAATCTTCGAATCAACAATGGCGTGTCTTGA
TGTAGCTAAAAATAGCTTAGATCCAATGCAGGTAAACCGTGCAGTTGACCTTCTAACACAAGCGAAAAAAATCTCTTTCT
TTGGTCTAGGTGCATCAGCTTCTGTAGCGCACGATGCCATGAACAAATTTTTCCGATTTAACATCCCTATCGCTTGTTTT
GACGACATCGTGATGCAACGCATGAGCTGCATCAATAGCACAGAAAATGATGTAGTAGTGTTAATTTCACACACAGGTCG
AACTAAAAGCTTGGTTGAAATCGCAGAGCTTGCTAAATCAAACGGCGCAACGGTTATTGCGATTACTGCAAAGGATTCAC
CTCTTGAAAAAATGGCATCTTTAGCTATTTGTTTAGATGTGCCGGAAGATACTGACGTATATATGCCAATGGCAAGTCGT
GTTGTTCAAATGACCGTTATTGATGTTCTAGCAACTGGCTTCACATTACGCCGTGGTGTTGGTTTTAGAGATAATCTGAA
GCGAGTTAAAGAAGCACTTAAAGATTCTCGCTACGGAAAAGATGAACGTTACCAATAG

Upstream 100 bases:

>100_bases
CAAACGTATATACTTATTCAAATAGATAATCTTAACCAAAGTGTCTTTTCAAATCACTCTGGTTAAGGTTATATCAAATT
AAAAATGTAGAAGAGCGCAT

Downstream 100 bases:

>100_bases
GTTTTACCTATCAATCTAAAAGGTATAATCATCTTTACTTAATTCATATTGATAGGCATAGTTAACCTATTGATTGCGAA
CCATATCCGCTAATAATTTT

Product: DNA-binding transcriptional regulator HexR

Products: NA

Alternate protein names: Hex regulon repressor [H]

Number of amino acids: Translated: 285; Mature: 285

Protein sequence:

>285_residues
MNTIEKIQNNLDNFSKSERKVAEVIMASPQTAIHSSIATLAKMADVSEPTVNRFCRRLDTKGFPDFKLHLAQSLANGTPY
VNRNVEENDGPDAYTHKIFESTMACLDVAKNSLDPMQVNRAVDLLTQAKKISFFGLGASASVAHDAMNKFFRFNIPIACF
DDIVMQRMSCINSTENDVVVLISHTGRTKSLVEIAELAKSNGATVIAITAKDSPLEKMASLAICLDVPEDTDVYMPMASR
VVQMTVIDVLATGFTLRRGVGFRDNLKRVKEALKDSRYGKDERYQ

Sequences:

>Translated_285_residues
MNTIEKIQNNLDNFSKSERKVAEVIMASPQTAIHSSIATLAKMADVSEPTVNRFCRRLDTKGFPDFKLHLAQSLANGTPY
VNRNVEENDGPDAYTHKIFESTMACLDVAKNSLDPMQVNRAVDLLTQAKKISFFGLGASASVAHDAMNKFFRFNIPIACF
DDIVMQRMSCINSTENDVVVLISHTGRTKSLVEIAELAKSNGATVIAITAKDSPLEKMASLAICLDVPEDTDVYMPMASR
VVQMTVIDVLATGFTLRRGVGFRDNLKRVKEALKDSRYGKDERYQ
>Mature_285_residues
MNTIEKIQNNLDNFSKSERKVAEVIMASPQTAIHSSIATLAKMADVSEPTVNRFCRRLDTKGFPDFKLHLAQSLANGTPY
VNRNVEENDGPDAYTHKIFESTMACLDVAKNSLDPMQVNRAVDLLTQAKKISFFGLGASASVAHDAMNKFFRFNIPIACF
DDIVMQRMSCINSTENDVVVLISHTGRTKSLVEIAELAKSNGATVIAITAKDSPLEKMASLAICLDVPEDTDVYMPMASR
VVQMTVIDVLATGFTLRRGVGFRDNLKRVKEALKDSRYGKDERYQ

Specific function: Represses the expression of the hex regulon (zwf, eda, glp and gap) [H]

COG id: COG1737

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1788159, Length=280, Percent_Identity=72.8571428571428, Blast_Score=431, Evalue=1e-122,
Organism=Escherichia coli, GI87082369, Length=240, Percent_Identity=24.5833333333333, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1788767, Length=262, Percent_Identity=26.7175572519084, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI87082130, Length=214, Percent_Identity=28.0373831775701, Blast_Score=86, Evalue=4e-18,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000281
- InterPro:   IPR001347
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01418 HTH_6; PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 31564; Mature: 31564

Theoretical pI: Translated: 7.46; Mature: 7.46

Prosite motif: PS51071 HTH_RPIR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTIEKIQNNLDNFSKSERKVAEVIMASPQTAIHSSIATLAKMADVSEPTVNRFCRRLDT
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCC
KGFPDFKLHLAQSLANGTPYVNRNVEENDGPDAYTHKIFESTMACLDVAKNSLDPMQVNR
CCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
AVDLLTQAKKISFFGLGASASVAHDAMNKFFRFNIPIACFDDIVMQRMSCINSTENDVVV
HHHHHHHHHHHHEEECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCEEE
LISHTGRTKSLVEIAELAKSNGATVIAITAKDSPLEKMASLAICLDVPEDTDVYMPMASR
EEECCCCHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHEEECCCCCCEEHHHHHH
VVQMTVIDVLATGFTLRRGVGFRDNLKRVKEALKDSRYGKDERYQ
HHHHHHHHHHHHCHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MNTIEKIQNNLDNFSKSERKVAEVIMASPQTAIHSSIATLAKMADVSEPTVNRFCRRLDT
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCC
KGFPDFKLHLAQSLANGTPYVNRNVEENDGPDAYTHKIFESTMACLDVAKNSLDPMQVNR
CCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
AVDLLTQAKKISFFGLGASASVAHDAMNKFFRFNIPIACFDDIVMQRMSCINSTENDVVV
HHHHHHHHHHHHEEECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCEEE
LISHTGRTKSLVEIAELAKSNGATVIAITAKDSPLEKMASLAICLDVPEDTDVYMPMASR
EEECCCCHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHEEECCCCCCEEHHHHHH
VVQMTVIDVLATGFTLRRGVGFRDNLKRVKEALKDSRYGKDERYQ
HHHHHHHHHHHHCHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 1704005; 7567469 [H]