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The map label for this gene is pta [H]

Identifier: 59711443

GI number: 59711443

Start: 921399

End: 923564

Strand: Reverse

Name: pta [H]

Synonym: VF_0836

Alternate gene names: 59711443

Gene position: 923564-921399 (Counterclockwise)

Preceding gene: 59711444

Following gene: 59711436

Centisome position: 31.87

GC content: 44.64

Gene sequence:

>2166_bases
ATGTCTCGTACTATTATGCTTGTTCCAATCAGTGCTGGTGTTGGTCTAACTAGCGCAAGTTTGGGTGTATTACGTTCAAT
GGAACGTAAAGGCGTAAGCGTTTCTTTTTACAAACCAATCTCTCAGCCTCGTCACGGTGGTGATCAACCTGATCTAACTA
CTTCAATCGTGACTAGCAGCAGCGATATCAAAGCAGCAGAACCAACTACAATCTCTCGTGCAGAAGAACTGCTACGTAAC
GAACAGTCTGACGTTCTTCTAGAAGAAATCGTTGCGCGTTACAAGTCAATCAGCCAAGGCACTGATGTGACACTTATCGA
AGGTTTAGTTCCTACTCGTAAACACCCATTTGCTAACCAATTAAACGGTGAAATTGCAAAAACTCTGGGTGCTGAGATTG
TGTTTGTAGCAACTCCTGGTACAGATAACCCTTCTCAACTTAAAGAGCGTATCGAAGTAGCATGTTCTAACTTTGGTGGC
ACTAAGAACAAACAAATCGCTGGCGTTATCATTAACAAGCTAAATGCACCTGTTGATGAAGCTGGTCGTACTCGCCCTGA
CCTATCTGAAATCTTTGATGATGCAGATGCAACGACTAAGACTAACCTTGAAGTAATGCAAATCTTCAACTCTAGTCCTA
TTCGTGTTCTTGGTTGTGTGCCTTGGAAAGTAGACCTAATTGCTACTCGTGCTATCGACATGGCTAAGCACTTAAATGCT
GAAATCATCAACGAAGGTGATATTGCTACTCGTCGTATTAAGAGCATCACTTTCTGTGCACGTTCTCTACCGCACATGAT
TGAGCACTTCAAACCAGGTTCTCTACTAGTAACTTCTGCTGACCGTCCTGACGTTATCGTTGCTGCATGTCTTGCTGCAA
TGAACGGCGTAGAAATCGGCGCAATCTTACTGACTGGCGGTTACGAAATCCCTCAATCAATTGCTGAACTTTGTAAGCCT
GCTCTAGAGTCTGGTCTTCCAATCTTCACTGCACAAGGTAACACTTGGCAGACGTCTCTAAATCTACAAAGCTTCAGCCT
TGAAGTTCCTGCAGATGATAAAGAGCGTATTGAGTTTGTTAACGAGCACGTTGCTAGCCACATTGATGGCCCTTGGATTG
ACTCTCTATCTGAAGGTACTGAAGGTATCCGTCGTCTAAGCCCACCAGCATTCCGTTACCAGTTAACTGAATTTGCTCGT
AAAGCGGCTAAACGTATCGTTCTTCCTGAAGGTGATGAGCCTCGTACAGTTAAAGCTGCGGCTATCTGTGCTGAGCGTGG
TATCGCGACTTGTGTTCTTTTAGGTAACCCTGAAGAAATCCGTCGTGTTGCAGCGCAACAAGGTGTTGAACTTGGTGCTG
GCGTTGAGATCATCGATTCTGATTCTGTACGTGAAAACTACGTTGCTCGTTTAGTTGAGCTACGTGGCGCGAAAGGCATG
ACTGAAGTTGTGGCTCGTGAAAAACTACAAGATTCTGTATTCCTTGGTACTATGATGCTTGAAGCGGGTGAAGTTGACGG
TCTTGTTTCTGGTGCGGTTCATACCACAGCAAACACTATCGTTCCTCCATTCCAAATCATCAAAACAGCTCCTGATGCTT
CTATCGTATCTTCAATCTTCTTCATGCTTCTTCCTGATCAAGTTCTTGTATACGGTGACTGTGCGATCAACCCTGATCCA
ACAGCTGAGCAACTTGCTGAAATCGCTATCCAATCTGCTGATTCTGCAATGGCGTTTGGTATCGACCCACGCGTTGCAAT
GATCTCTTACTCTACTGGTGAATCTGGTAAGGGTGCAGACGTTGATAAAGTACGCGAAGCAACTAAGATCGCTCAAGAGA
AACGTCCTGATCTAGTAATCGACGGTCCTCTACAGTACGATGCTGCAATCATGGAAAACGTAGCTGCTTCTAAAGCTCCT
AACTCTCCTGTAGCTGGTAAAGCAACTGTATTTGTATTCCCAGACCTAAACACTGGTAACACAACGTACAAAGCAGTTCA
ACGTTCTGCTGACCTAGTATCTATCGGTCCAATGCTTCAAGGCATGCGCAAGCCAGTAAATGACTTGTCTCGTGGTGCTC
TAGTTGACGATATCGTATACACAGTAGCACTAACAGCTATCCAAGCGGATCAAGCTGCACAAGCTGAAGAGAAAGTAATT
AACTAA

Upstream 100 bases:

>100_bases
ATATCTCCTAAAAGGCTAGCCATTAGGTTAGCCTTTTTTCTTTCTATGGCTTTATTTTTTCAATAAGGTCTCTTGCCCCA
ATAGTGTAGAGGAATTTTCC

Downstream 100 bases:

>100_bases
TTTCATGCTCTAGAAATAGAGCGTAGTTAATGAAAATAAGAAGACACGCGATGAAAGTTGCGTGTCTTTTTTTGTGCTTA
TAAAGTAGGGACTAGGGACG

Product: phosphate acetyltransferase

Products: NA

Alternate protein names: Phosphotransacetylase [H]

Number of amino acids: Translated: 721; Mature: 720

Protein sequence:

>721_residues
MSRTIMLVPISAGVGLTSASLGVLRSMERKGVSVSFYKPISQPRHGGDQPDLTTSIVTSSSDIKAAEPTTISRAEELLRN
EQSDVLLEEIVARYKSISQGTDVTLIEGLVPTRKHPFANQLNGEIAKTLGAEIVFVATPGTDNPSQLKERIEVACSNFGG
TKNKQIAGVIINKLNAPVDEAGRTRPDLSEIFDDADATTKTNLEVMQIFNSSPIRVLGCVPWKVDLIATRAIDMAKHLNA
EIINEGDIATRRIKSITFCARSLPHMIEHFKPGSLLVTSADRPDVIVAACLAAMNGVEIGAILLTGGYEIPQSIAELCKP
ALESGLPIFTAQGNTWQTSLNLQSFSLEVPADDKERIEFVNEHVASHIDGPWIDSLSEGTEGIRRLSPPAFRYQLTEFAR
KAAKRIVLPEGDEPRTVKAAAICAERGIATCVLLGNPEEIRRVAAQQGVELGAGVEIIDSDSVRENYVARLVELRGAKGM
TEVVAREKLQDSVFLGTMMLEAGEVDGLVSGAVHTTANTIVPPFQIIKTAPDASIVSSIFFMLLPDQVLVYGDCAINPDP
TAEQLAEIAIQSADSAMAFGIDPRVAMISYSTGESGKGADVDKVREATKIAQEKRPDLVIDGPLQYDAAIMENVAASKAP
NSPVAGKATVFVFPDLNTGNTTYKAVQRSADLVSIGPMLQGMRKPVNDLSRGALVDDIVYTVALTAIQADQAAQAEEKVI
N

Sequences:

>Translated_721_residues
MSRTIMLVPISAGVGLTSASLGVLRSMERKGVSVSFYKPISQPRHGGDQPDLTTSIVTSSSDIKAAEPTTISRAEELLRN
EQSDVLLEEIVARYKSISQGTDVTLIEGLVPTRKHPFANQLNGEIAKTLGAEIVFVATPGTDNPSQLKERIEVACSNFGG
TKNKQIAGVIINKLNAPVDEAGRTRPDLSEIFDDADATTKTNLEVMQIFNSSPIRVLGCVPWKVDLIATRAIDMAKHLNA
EIINEGDIATRRIKSITFCARSLPHMIEHFKPGSLLVTSADRPDVIVAACLAAMNGVEIGAILLTGGYEIPQSIAELCKP
ALESGLPIFTAQGNTWQTSLNLQSFSLEVPADDKERIEFVNEHVASHIDGPWIDSLSEGTEGIRRLSPPAFRYQLTEFAR
KAAKRIVLPEGDEPRTVKAAAICAERGIATCVLLGNPEEIRRVAAQQGVELGAGVEIIDSDSVRENYVARLVELRGAKGM
TEVVAREKLQDSVFLGTMMLEAGEVDGLVSGAVHTTANTIVPPFQIIKTAPDASIVSSIFFMLLPDQVLVYGDCAINPDP
TAEQLAEIAIQSADSAMAFGIDPRVAMISYSTGESGKGADVDKVREATKIAQEKRPDLVIDGPLQYDAAIMENVAASKAP
NSPVAGKATVFVFPDLNTGNTTYKAVQRSADLVSIGPMLQGMRKPVNDLSRGALVDDIVYTVALTAIQADQAAQAEEKVI
N
>Mature_720_residues
SRTIMLVPISAGVGLTSASLGVLRSMERKGVSVSFYKPISQPRHGGDQPDLTTSIVTSSSDIKAAEPTTISRAEELLRNE
QSDVLLEEIVARYKSISQGTDVTLIEGLVPTRKHPFANQLNGEIAKTLGAEIVFVATPGTDNPSQLKERIEVACSNFGGT
KNKQIAGVIINKLNAPVDEAGRTRPDLSEIFDDADATTKTNLEVMQIFNSSPIRVLGCVPWKVDLIATRAIDMAKHLNAE
IINEGDIATRRIKSITFCARSLPHMIEHFKPGSLLVTSADRPDVIVAACLAAMNGVEIGAILLTGGYEIPQSIAELCKPA
LESGLPIFTAQGNTWQTSLNLQSFSLEVPADDKERIEFVNEHVASHIDGPWIDSLSEGTEGIRRLSPPAFRYQLTEFARK
AAKRIVLPEGDEPRTVKAAAICAERGIATCVLLGNPEEIRRVAAQQGVELGAGVEIIDSDSVRENYVARLVELRGAKGMT
EVVAREKLQDSVFLGTMMLEAGEVDGLVSGAVHTTANTIVPPFQIIKTAPDASIVSSIFFMLLPDQVLVYGDCAINPDPT
AEQLAEIAIQSADSAMAFGIDPRVAMISYSTGESGKGADVDKVREATKIAQEKRPDLVIDGPLQYDAAIMENVAASKAPN
SPVAGKATVFVFPDLNTGNTTYKAVQRSADLVSIGPMLQGMRKPVNDLSRGALVDDIVYTVALTAIQADQAAQAEEKVIN

Specific function: Conversion of acetate to acetyl-CoA; second step. [C]

COG id: COG0857

COG function: function code R; BioD-like N-terminal domain of phosphotransacetylase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1788635, Length=712, Percent_Identity=74.1573033707865, Blast_Score=1093, Evalue=0.0,
Organism=Escherichia coli, GI1788800, Length=317, Percent_Identity=40.0630914826498, Blast_Score=223, Evalue=3e-59,
Organism=Escherichia coli, GI1788806, Length=344, Percent_Identity=31.1046511627907, Blast_Score=165, Evalue=8e-42,

Paralogues:

None

Copy number: 1420 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 1250 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010766
- InterPro:   IPR016475
- InterPro:   IPR004614
- InterPro:   IPR002505 [H]

Pfam domain/function: PF07085 DRTGG; PF01515 PTA_PTB [H]

EC number: =2.3.1.8 [H]

Molecular weight: Translated: 77259; Mature: 77128

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRTIMLVPISAGVGLTSASLGVLRSMERKGVSVSFYKPISQPRHGGDQPDLTTSIVTSS
CCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCHHEEECC
SDIKAAEPTTISRAEELLRNEQSDVLLEEIVARYKSISQGTDVTLIEGLVPTRKHPFANQ
CCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHH
LNGEIAKTLGAEIVFVATPGTDNPSQLKERIEVACSNFGGTKNKQIAGVIINKLNAPVDE
HCHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHCCCHHH
AGRTRPDLSEIFDDADATTKTNLEVMQIFNSSPIRVLGCVPWKVDLIATRAIDMAKHLNA
CCCCCCCHHHHHCCCCCCCCCCHHHHHHHCCCCEEEEEECCCEEHHHHHHHHHHHHHCCC
EIINEGDIATRRIKSITFCARSLPHMIEHFKPGSLLVTSADRPDVIVAACLAAMNGVEIG
CEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHCCCEEE
AILLTGGYEIPQSIAELCKPALESGLPIFTAQGNTWQTSLNLQSFSLEVPADDKERIEFV
EEEEECCCHHHHHHHHHHHHHHHCCCEEEEECCCEEEEEECEEEEEEECCCCHHHHHHHH
NEHVASHIDGPWIDSLSEGTEGIRRLSPPAFRYQLTEFARKAAKRIVLPEGDEPRTVKAA
HHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHEEECCCCCCCCHHHHH
AICAERGIATCVLLGNPEEIRRVAAQQGVELGAGVEIIDSDSVRENYVARLVELRGAKGM
HHHHHCCCEEEEEECCHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHHCCCCH
TEVVAREKLQDSVFLGTMMLEAGEVDGLVSGAVHTTANTIVPPFQIIKTAPDASIVSSIF
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCHHHCCCCCCCCHHHHHCCCCHHHHHHHH
FMLLPDQVLVYGDCAINPDPTAEQLAEIAIQSADSAMAFGIDPRVAMISYSTGESGKGAD
HHHCCCCEEEEECCCCCCCCCHHHHHHHHHHCCCCCEEECCCCCEEEEEECCCCCCCCCC
VDKVREATKIAQEKRPDLVIDGPLQYDAAIMENVAASKAPNSPVAGKATVFVFPDLNTGN
HHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCC
TTYKAVQRSADLVSIGPMLQGMRKPVNDLSRGALVDDIVYTVALTAIQADQAAQAEEKVI
HHHHHHHHCCCCEEHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
N
C
>Mature Secondary Structure 
SRTIMLVPISAGVGLTSASLGVLRSMERKGVSVSFYKPISQPRHGGDQPDLTTSIVTSS
CCEEEEEEECCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCHHEEECC
SDIKAAEPTTISRAEELLRNEQSDVLLEEIVARYKSISQGTDVTLIEGLVPTRKHPFANQ
CCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHH
LNGEIAKTLGAEIVFVATPGTDNPSQLKERIEVACSNFGGTKNKQIAGVIINKLNAPVDE
HCHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHCCCHHH
AGRTRPDLSEIFDDADATTKTNLEVMQIFNSSPIRVLGCVPWKVDLIATRAIDMAKHLNA
CCCCCCCHHHHHCCCCCCCCCCHHHHHHHCCCCEEEEEECCCEEHHHHHHHHHHHHHCCC
EIINEGDIATRRIKSITFCARSLPHMIEHFKPGSLLVTSADRPDVIVAACLAAMNGVEIG
CEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHCCCEEE
AILLTGGYEIPQSIAELCKPALESGLPIFTAQGNTWQTSLNLQSFSLEVPADDKERIEFV
EEEEECCCHHHHHHHHHHHHHHHCCCEEEEECCCEEEEEECEEEEEEECCCCHHHHHHHH
NEHVASHIDGPWIDSLSEGTEGIRRLSPPAFRYQLTEFARKAAKRIVLPEGDEPRTVKAA
HHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHEEECCCCCCCCHHHHH
AICAERGIATCVLLGNPEEIRRVAAQQGVELGAGVEIIDSDSVRENYVARLVELRGAKGM
HHHHHCCCEEEEEECCHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHHCCCCH
TEVVAREKLQDSVFLGTMMLEAGEVDGLVSGAVHTTANTIVPPFQIIKTAPDASIVSSIF
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCHHHCCCCCCCCHHHHHCCCCHHHHHHHH
FMLLPDQVLVYGDCAINPDPTAEQLAEIAIQSADSAMAFGIDPRVAMISYSTGESGKGAD
HHHCCCCEEEEECCCCCCCCCHHHHHHHHHHCCCCCEEECCCCCEEEEEECCCCCCCCCC
VDKVREATKIAQEKRPDLVIDGPLQYDAAIMENVAASKAPNSPVAGKATVFVFPDLNTGN
HHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCC
TTYKAVQRSADLVSIGPMLQGMRKPVNDLSRGALVDDIVYTVALTAIQADQAAQAEEKVI
HHHHHHHHCCCCEEHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
N
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7883769; 7918659; 9205837; 9278503; 2536666 [H]