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The map label for this gene is suhB [C]

Identifier: 59711221

GI number: 59711221

Start: 672196

End: 672999

Strand: Reverse

Name: suhB [C]

Synonym: VF_0614

Alternate gene names: 59711221

Gene position: 672999-672196 (Counterclockwise)

Preceding gene: 59711243

Following gene: 59711218

Centisome position: 23.23

GC content: 42.54

Gene sequence:

>804_bases
ATGCATCCAATGCTAAACATTGCTGTACGTGCTGCACGTAAAGCTGGTGACTTTGTTGCTAAATCTTTTGAGCAAACTGA
CAAAATTGAAACAACAAAGAAAGGCAACAACGAATTTATTACGAACATCGAAGCCGATGCTCAATACATTCTTGTTGACA
TGATCAAGAAATCTTACCCTGATCACAGCATCATTTCTGAAGAGTCTGGCCTAATTGAAGGTAAAGACACTGACATTCAA
TGGATCATTGACCCATTAGATGGCACGACTAACTTCGTTAAAGGTATCCCACACTTCTCTGTTTCTATTGCTGTTCGCAT
CAAAGGCCGTACAGAAGTAGCTTGTGTATACGATCCAATCCGTAATGAACTATTTACTGCTCAACGTGGTGCTGGTGCTC
AACGCAACAACCAACGTATGCGCGTTAAAGAGTTAAAAGATCTTAGCGAAGCTATCATCTCTACAGGTTTCCCATACCGT
CACAAACAACACACTGAAAGCTTCATGAAAGTTGTTGGTGCGTTATTCATCGAAGGTTCTGACGTTCGTCGTTCTGGTTG
TGCATCTCTAGACCTATGTTACCTAGCATCTGCACGCATGGACGGTTTTGTTGAACTAGGCCTTAAGCCTTGGGAAATGA
CAGCGGCTGACTTAATTGCTCGTGAAGCTGGCGTTATCTGTACTGACTTCGTTGGCGGTACTGATTACCTAAAATCTGGT
AACCTAGTTGCTGGTAGCCCACGTGTTGTTAAAGCGATGCTTAAAAAAGTTCGTGAAAACGGCAACGAAGCTATGATGAA
GTAA

Upstream 100 bases:

>100_bases
AAGAGAATGAATGAACAAAAAATAAACACTTCCTTTTTATAATAAGTCTGTGTATACTCGCCGCCGATTTCTGTTCTTTA
ACATCTTTTGGGATATTACT

Downstream 100 bases:

>100_bases
TTTCATTTATTGATTTAAAAAAAGGGAAGACAGATAAACTGTCTTCCCTTTTTTATAATAAAAAATCAAAAATCCCAACC
AAACTCAGTAAATAGTTTTT

Product: inositol monophosphatase

Products: NA

Alternate protein names: I-1-Pase; IMPase; Inositol-1-phosphatase [H]

Number of amino acids: Translated: 267; Mature: 267

Protein sequence:

>267_residues
MHPMLNIAVRAARKAGDFVAKSFEQTDKIETTKKGNNEFITNIEADAQYILVDMIKKSYPDHSIISEESGLIEGKDTDIQ
WIIDPLDGTTNFVKGIPHFSVSIAVRIKGRTEVACVYDPIRNELFTAQRGAGAQRNNQRMRVKELKDLSEAIISTGFPYR
HKQHTESFMKVVGALFIEGSDVRRSGCASLDLCYLASARMDGFVELGLKPWEMTAADLIAREAGVICTDFVGGTDYLKSG
NLVAGSPRVVKAMLKKVRENGNEAMMK

Sequences:

>Translated_267_residues
MHPMLNIAVRAARKAGDFVAKSFEQTDKIETTKKGNNEFITNIEADAQYILVDMIKKSYPDHSIISEESGLIEGKDTDIQ
WIIDPLDGTTNFVKGIPHFSVSIAVRIKGRTEVACVYDPIRNELFTAQRGAGAQRNNQRMRVKELKDLSEAIISTGFPYR
HKQHTESFMKVVGALFIEGSDVRRSGCASLDLCYLASARMDGFVELGLKPWEMTAADLIAREAGVICTDFVGGTDYLKSG
NLVAGSPRVVKAMLKKVRENGNEAMMK
>Mature_267_residues
MHPMLNIAVRAARKAGDFVAKSFEQTDKIETTKKGNNEFITNIEADAQYILVDMIKKSYPDHSIISEESGLIEGKDTDIQ
WIIDPLDGTTNFVKGIPHFSVSIAVRIKGRTEVACVYDPIRNELFTAQRGAGAQRNNQRMRVKELKDLSEAIISTGFPYR
HKQHTESFMKVVGALFIEGSDVRRSGCASLDLCYLASARMDGFVELGLKPWEMTAADLIAREAGVICTDFVGGTDYLKSG
NLVAGSPRVVKAMLKKVRENGNEAMMK

Specific function: Unknown

COG id: COG0483

COG function: function code G; Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Homo sapiens, GI7657236, Length=260, Percent_Identity=31.5384615384615, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI5031789, Length=258, Percent_Identity=29.4573643410853, Blast_Score=131, Evalue=7e-31,
Organism=Homo sapiens, GI221625487, Length=258, Percent_Identity=29.4573643410853, Blast_Score=131, Evalue=8e-31,
Organism=Homo sapiens, GI221625507, Length=144, Percent_Identity=33.3333333333333, Blast_Score=90, Evalue=2e-18,
Organism=Escherichia coli, GI1788882, Length=267, Percent_Identity=57.6779026217228, Blast_Score=353, Evalue=7e-99,
Organism=Escherichia coli, GI1790659, Length=206, Percent_Identity=23.3009708737864, Blast_Score=74, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI193202572, Length=253, Percent_Identity=30.4347826086957, Blast_Score=125, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI193202570, Length=254, Percent_Identity=29.5275590551181, Blast_Score=121, Evalue=4e-28,
Organism=Saccharomyces cerevisiae, GI6320493, Length=230, Percent_Identity=29.5652173913043, Blast_Score=95, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6321836, Length=231, Percent_Identity=26.4069264069264, Blast_Score=82, Evalue=1e-16,
Organism=Drosophila melanogaster, GI21357329, Length=260, Percent_Identity=34.2307692307692, Blast_Score=140, Evalue=7e-34,
Organism=Drosophila melanogaster, GI24664922, Length=263, Percent_Identity=26.615969581749, Blast_Score=124, Evalue=5e-29,
Organism=Drosophila melanogaster, GI21357957, Length=272, Percent_Identity=28.6764705882353, Blast_Score=120, Evalue=8e-28,
Organism=Drosophila melanogaster, GI24664926, Length=224, Percent_Identity=29.4642857142857, Blast_Score=120, Evalue=1e-27,
Organism=Drosophila melanogaster, GI21357303, Length=237, Percent_Identity=31.6455696202532, Blast_Score=119, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24664918, Length=247, Percent_Identity=33.1983805668016, Blast_Score=117, Evalue=9e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550
- InterPro:   IPR022337 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.25 [H]

Molecular weight: Translated: 29567; Mature: 29567

Theoretical pI: Translated: 7.97; Mature: 7.97

Prosite motif: PS00629 IMP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHPMLNIAVRAARKAGDFVAKSFEQTDKIETTKKGNNEFITNIEADAQYILVDMIKKSYP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHCCC
DHSIISEESGLIEGKDTDIQWIIDPLDGTTNFVKGIPHFSVSIAVRIKGRTEVACVYDPI
CCHHCCCCCCCCCCCCCCEEEEEECCCCCHHHHHCCCCEEEEEEEEECCCCEEEEEECHH
RNELFTAQRGAGAQRNNQRMRVKELKDLSEAIISTGFPYRHKQHTESFMKVVGALFIEGS
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCC
DVRRSGCASLDLCYLASARMDGFVELGLKPWEMTAADLIAREAGVICTDFVGGTDYLKSG
CCCCCCCCCHHHHHHHHHCCCCCEECCCCCHHHHHHHHHHHHCCCEEEECCCCHHHHCCC
NLVAGSPRVVKAMLKKVRENGNEAMMK
CEEECCHHHHHHHHHHHHHCCCHHCCC
>Mature Secondary Structure
MHPMLNIAVRAARKAGDFVAKSFEQTDKIETTKKGNNEFITNIEADAQYILVDMIKKSYP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHCCC
DHSIISEESGLIEGKDTDIQWIIDPLDGTTNFVKGIPHFSVSIAVRIKGRTEVACVYDPI
CCHHCCCCCCCCCCCCCCEEEEEECCCCCHHHHHCCCCEEEEEEEEECCCCEEEEEECHH
RNELFTAQRGAGAQRNNQRMRVKELKDLSEAIISTGFPYRHKQHTESFMKVVGALFIEGS
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCC
DVRRSGCASLDLCYLASARMDGFVELGLKPWEMTAADLIAREAGVICTDFVGGTDYLKSG
CCCCCCCCCHHHHHHHHHCCCCCEECCCCCHHHHHHHHHHHHCCCEEEECCCCHHHHCCC
NLVAGSPRVVKAMLKKVRENGNEAMMK
CEEECCHHHHHHHHHHHHHCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]