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The map label for this gene is malP [H]

Identifier: 56965342

GI number: 56965342

Start: 3725708

End: 3727291

Strand: Direct

Name: malP [H]

Synonym: ABC3580

Alternate gene names: 56965342

Gene position: 3725708-3727291 (Clockwise)

Preceding gene: 56965336

Following gene: 56965343

Centisome position: 86.57

GC content: 42.05

Gene sequence:

>1584_bases
ATGAACGCAATCAAGCGGTTTGGCAGCGCGATGATTGTCCCTGTTCTCTTATTCGCATTTTTTGGCATTGTCGTCGGCCT
GGCAACTTTATTTAAAAACCCGGCGATTATGGGAGACATCGCTGCAGAAGGGACGATGTGGTACAAGGTTTGGTCACTGA
TTGAAAGTGGAGGCTGGACCATTTTTAATCATATGGAGCTGGCGTTTGTTATCGGCTTGCCCATTTCATTGGCAAAAAAA
GCGCAAGCACGGGCCACACTTGCAGCATTGATGGTTTACCTTGTTTTCAATAATTTTATTAATGCGATTTTGACACTTTG
GCCGTCCACTTTCGGCGTCGATCTATCACAAGGGGTCGAGAACATAACAGGTGTTAAAGAAATTGCCGGTATCCCTACAT
TGGATACAAATATCATTGGCGCCATTGTCATATCTGCGGTTGTGATTTGGATCCATAATCGTTTTTATGATCAAAAGCTT
CCTGAAATGCTTGGCATTTTCCAGGGTCTCGTCTTTGTGGTGATCATTGGCTTTTTTGTAATGATTCCTTTCGCTTTTCT
CGTTGCTTTTGTATGGCCGTATGTCCAGCAAGGCATTGGTTCCCTCCAAGGGTTCATCTCACAAGCTGGTTATGTTGGTG
TCTGGCTGTTTCATTTCTTGGAAAGGGTTTTAATACCGACGGGGCTGCATCATTTTATTTACACTCCTTTTGAATTTGGT
CCGGCTGCTGTAAATGAAGGGTTAAAACCATATTGGATTGCCAATTTAAATGATTTTGCTACTTCAACTTCAGCGTTAAA
AGATCTTTATCCATATGGGTTTTTACTGCATGGAAATATTAAGATGTTCGGCTGTTTAGGGATCGCACTCGCCATGTATT
ATTCAACACCAAAAGAAAACCGAAAAAAAGTGCTTGCGCTCGTATTGCCTGCAACATTAACAGCGATATTTGCGGGAATT
ACAGAACCGCTTGAATTTACATTTCTATTTATCGCGCCCTATTTATTTGTGATCCATGCCCTTCTTGGCGCGACTATGGT
AACGCTGATGAACATGTTTGGCGTCGTCGGCATGATGGGCGGCGGATTAATTGAAATAGCCGCGTTAAACTGGATTCCAC
TCGCTTCTAACCACGGAAGCATTTATATCGTCCAAGCCATGATTGGGCTTATATTTGCAGCACTGTACTTTGTCCTGTTC
AGATGGATGATTGTTAAATTTGATATTCCATTACCAGGGCGAAAAAAGGAAGAGAAGGCTAGGCTATACACAAAACAAGA
TTATCAGAAGGTTAAAAAAGGGAGTAACTCTGAAAAACAAGCTGCGGCAACTTACGAGTCTGAGTATGAAGAGAAAGCGG
TCTATTACTTAGAAGGCCTTGGCGGCAAAGAAAACATTAAAGATGTGACAAACTGTGCAACGCGTCTGCGTGTTACAGTG
ATTGATCCTAGTTTGGTCAAAGATAGCGACTACTTCACAAACAATAAAATGGCTCATGGGTTGGCTAAAAGCGGCCAAAG
CATACAAATTATTGTTGGTTTGAGTGTACCGCAAGTGAGAGATTCCTTTGAAGCAAAATTATAA

Upstream 100 bases:

>100_bases
TCTAATCGTACAACTTGATTTCTAAATGCGTCAAACCTATTGGGTTTTGAAAGCGCTGCCTTTACAGTTAAATTGTAGAC
CACGCAAAGGAGTTTTGCTT

Downstream 100 bases:

>100_bases
ATATATAGGAGAGGGAGAGATTTACTATGAAAACATTTAACATTACCATCGCTGGAGGCGGAAGCACATTTACACCAGGG
ATTATTTTGATGCTGCTCGA

Product: PTS system, glucose/maltose/N-acetylglucosamine-specific enzyme II, BC component

Products: NA

Alternate protein names: Maltose permease IIC component; PTS system maltose-specific EIIC component; Maltose-specific phosphotransferase enzyme IIB component; PTS system maltose-specific EIIB component [H]

Number of amino acids: Translated: 527; Mature: 527

Protein sequence:

>527_residues
MNAIKRFGSAMIVPVLLFAFFGIVVGLATLFKNPAIMGDIAAEGTMWYKVWSLIESGGWTIFNHMELAFVIGLPISLAKK
AQARATLAALMVYLVFNNFINAILTLWPSTFGVDLSQGVENITGVKEIAGIPTLDTNIIGAIVISAVVIWIHNRFYDQKL
PEMLGIFQGLVFVVIIGFFVMIPFAFLVAFVWPYVQQGIGSLQGFISQAGYVGVWLFHFLERVLIPTGLHHFIYTPFEFG
PAAVNEGLKPYWIANLNDFATSTSALKDLYPYGFLLHGNIKMFGCLGIALAMYYSTPKENRKKVLALVLPATLTAIFAGI
TEPLEFTFLFIAPYLFVIHALLGATMVTLMNMFGVVGMMGGGLIEIAALNWIPLASNHGSIYIVQAMIGLIFAALYFVLF
RWMIVKFDIPLPGRKKEEKARLYTKQDYQKVKKGSNSEKQAAATYESEYEEKAVYYLEGLGGKENIKDVTNCATRLRVTV
IDPSLVKDSDYFTNNKMAHGLAKSGQSIQIIVGLSVPQVRDSFEAKL

Sequences:

>Translated_527_residues
MNAIKRFGSAMIVPVLLFAFFGIVVGLATLFKNPAIMGDIAAEGTMWYKVWSLIESGGWTIFNHMELAFVIGLPISLAKK
AQARATLAALMVYLVFNNFINAILTLWPSTFGVDLSQGVENITGVKEIAGIPTLDTNIIGAIVISAVVIWIHNRFYDQKL
PEMLGIFQGLVFVVIIGFFVMIPFAFLVAFVWPYVQQGIGSLQGFISQAGYVGVWLFHFLERVLIPTGLHHFIYTPFEFG
PAAVNEGLKPYWIANLNDFATSTSALKDLYPYGFLLHGNIKMFGCLGIALAMYYSTPKENRKKVLALVLPATLTAIFAGI
TEPLEFTFLFIAPYLFVIHALLGATMVTLMNMFGVVGMMGGGLIEIAALNWIPLASNHGSIYIVQAMIGLIFAALYFVLF
RWMIVKFDIPLPGRKKEEKARLYTKQDYQKVKKGSNSEKQAAATYESEYEEKAVYYLEGLGGKENIKDVTNCATRLRVTV
IDPSLVKDSDYFTNNKMAHGLAKSGQSIQIIVGLSVPQVRDSFEAKL
>Mature_527_residues
MNAIKRFGSAMIVPVLLFAFFGIVVGLATLFKNPAIMGDIAAEGTMWYKVWSLIESGGWTIFNHMELAFVIGLPISLAKK
AQARATLAALMVYLVFNNFINAILTLWPSTFGVDLSQGVENITGVKEIAGIPTLDTNIIGAIVISAVVIWIHNRFYDQKL
PEMLGIFQGLVFVVIIGFFVMIPFAFLVAFVWPYVQQGIGSLQGFISQAGYVGVWLFHFLERVLIPTGLHHFIYTPFEFG
PAAVNEGLKPYWIANLNDFATSTSALKDLYPYGFLLHGNIKMFGCLGIALAMYYSTPKENRKKVLALVLPATLTAIFAGI
TEPLEFTFLFIAPYLFVIHALLGATMVTLMNMFGVVGMMGGGLIEIAALNWIPLASNHGSIYIVQAMIGLIFAALYFVLF
RWMIVKFDIPLPGRKKEEKARLYTKQDYQKVKKGSNSEKQAAATYESEYEEKAVYYLEGLGGKENIKDVTNCATRLRVTV
IDPSLVKDSDYFTNNKMAHGLAKSGQSIQIIVGLSVPQVRDSFEAKL

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787908, Length=538, Percent_Identity=30.8550185873606, Blast_Score=220, Evalue=2e-58,
Organism=Escherichia coli, GI1787343, Length=527, Percent_Identity=27.7039848197343, Blast_Score=184, Evalue=2e-47,
Organism=Escherichia coli, GI1786894, Length=477, Percent_Identity=32.0754716981132, Blast_Score=172, Evalue=5e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018113
- InterPro:   IPR004719
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR010975 [H]

Pfam domain/function: PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 58330; Mature: 58330

Theoretical pI: Translated: 8.96; Mature: 8.96

Prosite motif: PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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ECCHHHCCCCCCCCCHHHHHHHCCCCEEEEEEECCCHHHHHHHCCCC
>Mature Secondary Structure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ECCHHHCCCCCCCCCHHHHHHHCCCCEEEEEEECCCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8704981; 9384377; 11489864 [H]