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The map label for this gene is ftsY [H]

Identifier: 54295510

GI number: 54295510

Start: 2963763

End: 2964830

Strand: Reverse

Name: ftsY [H]

Synonym: lpl2597

Alternate gene names: 54295510

Gene position: 2964830-2963763 (Counterclockwise)

Preceding gene: 54295518

Following gene: 54295509

Centisome position: 88.62

GC content: 44.19

Gene sequence:

>1068_bases
ATGATTAAATGGTTTAAACGAAATCAAAATTCCGAACCAAATTTGGATACCGAAGAGCAGCAAGATCATGCCGAAAGCAG
CAGGGAATCCAGGCTTGAAGAGCCCCGGGAACTGACTGCCAAAGAGCCTTCGCCCAAAGAAAGTATTTTTGCCCGGTTTA
GGAAAGGCCTTAGCAAAACCCGTCATCAATTGGGGGAAGGCATAAGTCGGCTGCTGTTAGGTAAAAAAGAAATCAGCCAG
GAGTTACTCGAAGAGCTGGAGACCTTATTAATTAGTGCTGATTTAGGTTTGGACACCACTCAAGACGTATTGAAACAGCT
AAATGAAGGCTTGGCAAGAAAGCAACTGTCTAATGGTGACGCAGTTTATCAGACTTTAAAGACAAATTTGCAAACGATTT
TGAGCCAGGAAGAGAAACCGCTTTCCATAGAAACTGAAGACGGCTCTCCCTTTGTCATATTAATGGTTGGTGTCAATGGA
GCCGGTAAAACAACCACGATTGGTAAACTAGCCAAACAATTCCAAAAGCAGGGAAAAAAAGTTATGTTAGCTGCGGGGGA
TACGTTTCGGGCGGCTGCGGTGGAACAATTGCATGTATGGGGCGAAAGAAATGGCATACCTGTTATTGCCCAGCATACCG
GCGCTGACAGTGCCTCAGTAATTTTTGATGCTCTTCAGGCTGCCAAAGCGAGAAAAATAGATGTTTTAATCGCTGATACA
GCCGGGCGTTTGCATACTCAAAGCAATTTAATGGAAGAGTTGAAAAAAGTGAAAAGAGTCATGCAGAAACTCGATCCCAA
GGCACCTCATGAAACCATGTTGGTATTGGATGCGAGTATTGGGCAGAACGCCTTGGCTCAGGCAAAGCAGTTTCATGAAG
CAGTACAATTAACTGGAATTACTATGACCAAGCTTGATGGGACAGCCAAAGGCGGGATATTATTTGCTATAGCGAATGAT
TTGGGGATACCTTTTCGTTATTTAGGGGTAGGGGAGGGCATTGAAGATTTGAGGCCCTTTGACGCAGCGCAATTTGTTAG
TGCGATATTCGATGATGATCACATTTGA

Upstream 100 bases:

>100_bases
GAGAGTAGCATCATAAGAGAAATGAGTAATTTGTGCACAATGTCACCTCAAAGCTAAAAAGATGATAGAATTTCATATTT
TTAAGGAATTGTACACTAAA

Downstream 100 bases:

>100_bases
CCAGGTTAGTAAACGTTATCCGGGGGGCTTTGAGGCATTAAGCCAAGTTAATTTTTCTTTGCAAAAAGGAGAAATGGTCT
TTCTTACTGGCCATTCAGGT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 355; Mature: 355

Protein sequence:

>355_residues
MIKWFKRNQNSEPNLDTEEQQDHAESSRESRLEEPRELTAKEPSPKESIFARFRKGLSKTRHQLGEGISRLLLGKKEISQ
ELLEELETLLISADLGLDTTQDVLKQLNEGLARKQLSNGDAVYQTLKTNLQTILSQEEKPLSIETEDGSPFVILMVGVNG
AGKTTTIGKLAKQFQKQGKKVMLAAGDTFRAAAVEQLHVWGERNGIPVIAQHTGADSASVIFDALQAAKARKIDVLIADT
AGRLHTQSNLMEELKKVKRVMQKLDPKAPHETMLVLDASIGQNALAQAKQFHEAVQLTGITMTKLDGTAKGGILFAIAND
LGIPFRYLGVGEGIEDLRPFDAAQFVSAIFDDDHI

Sequences:

>Translated_355_residues
MIKWFKRNQNSEPNLDTEEQQDHAESSRESRLEEPRELTAKEPSPKESIFARFRKGLSKTRHQLGEGISRLLLGKKEISQ
ELLEELETLLISADLGLDTTQDVLKQLNEGLARKQLSNGDAVYQTLKTNLQTILSQEEKPLSIETEDGSPFVILMVGVNG
AGKTTTIGKLAKQFQKQGKKVMLAAGDTFRAAAVEQLHVWGERNGIPVIAQHTGADSASVIFDALQAAKARKIDVLIADT
AGRLHTQSNLMEELKKVKRVMQKLDPKAPHETMLVLDASIGQNALAQAKQFHEAVQLTGITMTKLDGTAKGGILFAIAND
LGIPFRYLGVGEGIEDLRPFDAAQFVSAIFDDDHI
>Mature_355_residues
MIKWFKRNQNSEPNLDTEEQQDHAESSRESRLEEPRELTAKEPSPKESIFARFRKGLSKTRHQLGEGISRLLLGKKEISQ
ELLEELETLLISADLGLDTTQDVLKQLNEGLARKQLSNGDAVYQTLKTNLQTILSQEEKPLSIETEDGSPFVILMVGVNG
AGKTTTIGKLAKQFQKQGKKVMLAAGDTFRAAAVEQLHVWGERNGIPVIAQHTGADSASVIFDALQAAKARKIDVLIADT
AGRLHTQSNLMEELKKVKRVMQKLDPKAPHETMLVLDASIGQNALAQAKQFHEAVQLTGITMTKLDGTAKGGILFAIAND
LGIPFRYLGVGEGIEDLRPFDAAQFVSAIFDDDHI

Specific function: Functional homolog of SRP receptor. Probably involved in the reception and insertion of a subset of proteins at the cytoplasmic membrane. Binds to the ribosome in the presence of the SRP particle and a non-hydrolyzable GTP analog. This abolishes trigger f

COG id: COG0552

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI4507215, Length=276, Percent_Identity=30.4347826086957, Blast_Score=136, Evalue=3e-32,
Organism=Homo sapiens, GI226371618, Length=203, Percent_Identity=36.4532019704434, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI23308697, Length=332, Percent_Identity=27.710843373494, Blast_Score=108, Evalue=9e-24,
Organism=Homo sapiens, GI295424842, Length=332, Percent_Identity=27.710843373494, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI89061728, Length=143, Percent_Identity=32.1678321678322, Blast_Score=84, Evalue=2e-16,
Organism=Escherichia coli, GI1789874, Length=321, Percent_Identity=64.1744548286604, Blast_Score=394, Evalue=1e-111,
Organism=Escherichia coli, GI1788963, Length=276, Percent_Identity=35.1449275362319, Blast_Score=169, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI17539958, Length=269, Percent_Identity=28.2527881040892, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI193206261, Length=311, Percent_Identity=29.903536977492, Blast_Score=118, Evalue=4e-27,
Organism=Saccharomyces cerevisiae, GI6325345, Length=252, Percent_Identity=34.9206349206349, Blast_Score=142, Evalue=6e-35,
Organism=Saccharomyces cerevisiae, GI6320498, Length=330, Percent_Identity=27.5757575757576, Blast_Score=105, Evalue=1e-23,
Organism=Drosophila melanogaster, GI17647949, Length=203, Percent_Identity=35.9605911330049, Blast_Score=129, Evalue=3e-30,
Organism=Drosophila melanogaster, GI24641198, Length=316, Percent_Identity=26.5822784810127, Blast_Score=104, Evalue=8e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004390
- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N [H]

EC number: NA

Molecular weight: Translated: 39057; Mature: 39057

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKWFKRNQNSEPNLDTEEQQDHAESSRESRLEEPRELTAKEPSPKESIFARFRKGLSKT
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHCCCCCCCHHHHHHHHHHHHHHH
RHQLGEGISRLLLGKKEISQELLEELETLLISADLGLDTTQDVLKQLNEGLARKQLSNGD
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCH
AVYQTLKTNLQTILSQEEKPLSIETEDGSPFVILMVGVNGAGKTTTIGKLAKQFQKQGKK
HHHHHHHHHHHHHHCCCCCCCEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCE
VMLAAGDTFRAAAVEQLHVWGERNGIPVIAQHTGADSASVIFDALQAAKARKIDVLIADT
EEEECCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCEEEEEEECC
AGRLHTQSNLMEELKKVKRVMQKLDPKAPHETMLVLDASIGQNALAQAKQFHEAVQLTGI
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCE
TMTKLDGTAKGGILFAIANDLGIPFRYLGVGEGIEDLRPFDAAQFVSAIFDDDHI
EEEECCCCCCCCEEEEEECCCCCCEEEEECCCCHHHCCCCCHHHHHHHHHCCCCC
>Mature Secondary Structure
MIKWFKRNQNSEPNLDTEEQQDHAESSRESRLEEPRELTAKEPSPKESIFARFRKGLSKT
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHCCCCCCCHHHHHHHHHHHHHHH
RHQLGEGISRLLLGKKEISQELLEELETLLISADLGLDTTQDVLKQLNEGLARKQLSNGD
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCH
AVYQTLKTNLQTILSQEEKPLSIETEDGSPFVILMVGVNGAGKTTTIGKLAKQFQKQGKK
HHHHHHHHHHHHHHCCCCCCCEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCE
VMLAAGDTFRAAAVEQLHVWGERNGIPVIAQHTGADSASVIFDALQAAKARKIDVLIADT
EEEECCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCEEEEEEECC
AGRLHTQSNLMEELKKVKRVMQKLDPKAPHETMLVLDASIGQNALAQAKQFHEAVQLTGI
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCE
TMTKLDGTAKGGILFAIANDLGIPFRYLGVGEGIEDLRPFDAAQFVSAIFDDDHI
EEEECCCCCCCCEEEEEECCCCCCEEEEECCCCHHHCCCCCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 3025556; 8041620; 9278503; 2161989; 8194520; 9002525 [H]