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The map label for this gene is murB [H]

Identifier: 54295450

GI number: 54295450

Start: 2893143

End: 2894069

Strand: Reverse

Name: murB [H]

Synonym: lpl2536

Alternate gene names: 54295450

Gene position: 2894069-2893143 (Counterclockwise)

Preceding gene: 54295451

Following gene: 54295449

Centisome position: 86.5

GC content: 44.12

Gene sequence:

>927_bases
ATGAGCATAACGGGAATAGACAGCAGTCATGTAACAGAGTCTCAGGGCACTTTGCTTTTCAATGAGCCTTTGGCCGAGTA
TACTACCTGGCGAGTTGGTGGCCCTGCAGCGAGGCTCTATAAACCAGCAAATATTGATGATTTGGCTTTGTTTTTAAGTC
GATTGCCTTTTGATGAGCCATTATTATGGTTAGGTTTAGGCTCTAATTCTCTAATTCGTGATGGCGGTTTTTCCGGTACC
GTGATTCTCACTCAGGGCTGTTTAAAAGAAATGACCCTATTGAGCGATAACTGCATTCGGGTTGAGGCAGGGGTATCCTG
TGCCAGTATGGCTCGTTTTTCTGCGCGTAATAATCTGTCAGGAGGAGAGTTTTGGGCTGGTATCCCCGGTACCATGGGTG
GTGCTCTGCGAATGAATGCCGGTTGTCATGGAGGTGAAACCTGGCAGTCGGTTATTGAAGTACAAACGATAAATCGTCGA
GGTGAAATCAGAACCCGTAAACCGGAAGAATTTGAAGTAGCTTATCGACATGTTGCTGGCTTGGGAGATGAATGGTTTAT
TTCCGCAAAGCTTCAGCTATCACCAGGTAATAAAGAGACATCCTTGCAATTAATTAAGGATTTATTGGCTCATAGAGCCA
AGACCCAACCAACTAATGAATATAATTGTGGGTCGGTATTTAGAAACCCTCCTGGAGATTTTGCAGCGCGGCTTATTGAA
TCTTGTGGCCTCAAGGGGGTAAGTATCGGTGGGGCAGTGGTTTCTGAAAAACATGCCAATTTTATTATCAATCATCAAGG
TACTGCCACCGCAGCTAATATTGAAGCCTTGATTCATTTGGTGCAAACTAAAGTTCGAGAACAAACATCTATAGAGTTGA
TACGCGAAGTACATATCATTGGAGACGCTAATGTCCAAACCCGTTAA

Upstream 100 bases:

>100_bases
TAGATGAATTTATTAAAGATGGTGATGTTATTTTGATGCAGGGAGCTGGAAGTATCGGCCAAATGGCAGTGAACCTGATG
AAAAACATGTGAGAACGAAC

Downstream 100 bases:

>100_bases
TTTGGTTTTACTTTATGGTGGAAAATCAGGCGAGCATGAAGTGTCATTGGTTTCTGCTGCATCGGTTTTAAAACACCTGG
ATTCCGAGAAATATCATATT

Product: UDP-N-acetylenolpyruvoylglucosamine reductase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase [H]

Number of amino acids: Translated: 308; Mature: 307

Protein sequence:

>308_residues
MSITGIDSSHVTESQGTLLFNEPLAEYTTWRVGGPAARLYKPANIDDLALFLSRLPFDEPLLWLGLGSNSLIRDGGFSGT
VILTQGCLKEMTLLSDNCIRVEAGVSCASMARFSARNNLSGGEFWAGIPGTMGGALRMNAGCHGGETWQSVIEVQTINRR
GEIRTRKPEEFEVAYRHVAGLGDEWFISAKLQLSPGNKETSLQLIKDLLAHRAKTQPTNEYNCGSVFRNPPGDFAARLIE
SCGLKGVSIGGAVVSEKHANFIINHQGTATAANIEALIHLVQTKVREQTSIELIREVHIIGDANVQTR

Sequences:

>Translated_308_residues
MSITGIDSSHVTESQGTLLFNEPLAEYTTWRVGGPAARLYKPANIDDLALFLSRLPFDEPLLWLGLGSNSLIRDGGFSGT
VILTQGCLKEMTLLSDNCIRVEAGVSCASMARFSARNNLSGGEFWAGIPGTMGGALRMNAGCHGGETWQSVIEVQTINRR
GEIRTRKPEEFEVAYRHVAGLGDEWFISAKLQLSPGNKETSLQLIKDLLAHRAKTQPTNEYNCGSVFRNPPGDFAARLIE
SCGLKGVSIGGAVVSEKHANFIINHQGTATAANIEALIHLVQTKVREQTSIELIREVHIIGDANVQTR
>Mature_307_residues
SITGIDSSHVTESQGTLLFNEPLAEYTTWRVGGPAARLYKPANIDDLALFLSRLPFDEPLLWLGLGSNSLIRDGGFSGTV
ILTQGCLKEMTLLSDNCIRVEAGVSCASMARFSARNNLSGGEFWAGIPGTMGGALRMNAGCHGGETWQSVIEVQTINRRG
EIRTRKPEEFEVAYRHVAGLGDEWFISAKLQLSPGNKETSLQLIKDLLAHRAKTQPTNEYNCGSVFRNPPGDFAARLIES
CGLKGVSIGGAVVSEKHANFIINHQGTATAANIEALIHLVQTKVREQTSIELIREVHIIGDANVQTR

Specific function: Cell wall formation [H]

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094 [H]

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C [H]

EC number: =1.1.1.158 [H]

Molecular weight: Translated: 33431; Mature: 33300

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSITGIDSSHVTESQGTLLFNEPLAEYTTWRVGGPAARLYKPANIDDLALFLSRLPFDEP
CEECCCCCCCCCCCCCCEEECCCHHHHHEEECCCCHHHHCCCCCHHHHHHHHHHCCCCCC
LLWLGLGSNSLIRDGGFSGTVILTQGCLKEMTLLSDNCIRVEAGVSCASMARFSARNNLS
EEEEECCCCCEEECCCCCCEEEEEHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHCCCCC
GGEFWAGIPGTMGGALRMNAGCHGGETWQSVIEVQTINRRGEIRTRKPEEFEVAYRHVAG
CCCEEECCCCCCCCCEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHC
LGDEWFISAKLQLSPGNKETSLQLIKDLLAHRAKTQPTNEYNCGSVFRNPPGDFAARLIE
CCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHH
SCGLKGVSIGGAVVSEKHANFIINHQGTATAANIEALIHLVQTKVREQTSIELIREVHII
HCCCCCEECCCHHEECCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
GDANVQTR
ECCCCCCC
>Mature Secondary Structure 
SITGIDSSHVTESQGTLLFNEPLAEYTTWRVGGPAARLYKPANIDDLALFLSRLPFDEP
EECCCCCCCCCCCCCCEEECCCHHHHHEEECCCCHHHHCCCCCHHHHHHHHHHCCCCCC
LLWLGLGSNSLIRDGGFSGTVILTQGCLKEMTLLSDNCIRVEAGVSCASMARFSARNNLS
EEEEECCCCCEEECCCCCCEEEEEHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHCCCCC
GGEFWAGIPGTMGGALRMNAGCHGGETWQSVIEVQTINRRGEIRTRKPEEFEVAYRHVAG
CCCEEECCCCCCCCCEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHC
LGDEWFISAKLQLSPGNKETSLQLIKDLLAHRAKTQPTNEYNCGSVFRNPPGDFAARLIE
CCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHH
SCGLKGVSIGGAVVSEKHANFIINHQGTATAANIEALIHLVQTKVREQTSIELIREVHII
HCCCCCEECCCHHEECCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
GDANVQTR
ECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA