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The map label for this gene is pgsA [H]

Identifier: 54295132

GI number: 54295132

Start: 2526541

End: 2527104

Strand: Reverse

Name: pgsA [H]

Synonym: lpl2212

Alternate gene names: 54295132

Gene position: 2527104-2526541 (Counterclockwise)

Preceding gene: 54295133

Following gene: 54295131

Centisome position: 75.53

GC content: 40.07

Gene sequence:

>564_bases
GTGAGTACGTTAACCAGTTTGCCTAATATATTAACCTTAATGCGGATTTCGATCATTCCAGTATTTATTATGGTATTTTA
TTTTCCTTTCAAATGGGCTCATCCTACCGCTGCTGTTCTTTTTGCTATTGCAAGCATTACTGATTGGCTAGACGGTTATT
TGGCGCGCAAACTTGAAATGATGTCTCATTTTGGAGCTTTTCTTGATCCCGTCGCCGATAAATTATTGGTATCGACAAGC
TTGTTATTGTTAGTTGGAGCGAAGGATATAGATTATATCACTATACCTGCAATCGTAATCGTTGGACGAGAAATTGTGAT
TTCAGCCTTGCGCGAGTGGATGGCTGAAGTTGGAAGTCGTGCTAGTGTTGCCGTTGGGTATATAGGGAAAGTTAAAACTT
CTTTGCAAATGATCGCTTTGGTATTATTGCTGGCATTTAATCCCCTTGTCTCCTGGTGGGGGAGCTTAGGGTTTGCTCTT
CTTTATGTGTCTGCTATTTTGACGATTTGGTCCATGGTGATTTATTTGGCTATTGCCTGGCCAGAGTTAATGAAAAAAAG
TTAA

Upstream 100 bases:

>100_bases
CGCTTAAGGCAGCAGGTGCTTTGGCTGTGTTTGATGATTATAAGCTATTGTCAGCTTATCTGATGTTGCCGGAAGCATAA
AAAAAGGGGGATGTTCAGCA

Downstream 100 bases:

>100_bases
TTTTGCTGTTGACAGGGTATTTATTTTCGGTAGAATCTCATCCCGTAGAGACGCGGGAATAGCTCAGTTGGTAGAGCATA
ACCTTGCCAAGGTTAGGGTC

Product: hypothetical protein

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 187; Mature: 186

Protein sequence:

>187_residues
MSTLTSLPNILTLMRISIIPVFIMVFYFPFKWAHPTAAVLFAIASITDWLDGYLARKLEMMSHFGAFLDPVADKLLVSTS
LLLLVGAKDIDYITIPAIVIVGREIVISALREWMAEVGSRASVAVGYIGKVKTSLQMIALVLLLAFNPLVSWWGSLGFAL
LYVSAILTIWSMVIYLAIAWPELMKKS

Sequences:

>Translated_187_residues
MSTLTSLPNILTLMRISIIPVFIMVFYFPFKWAHPTAAVLFAIASITDWLDGYLARKLEMMSHFGAFLDPVADKLLVSTS
LLLLVGAKDIDYITIPAIVIVGREIVISALREWMAEVGSRASVAVGYIGKVKTSLQMIALVLLLAFNPLVSWWGSLGFAL
LYVSAILTIWSMVIYLAIAWPELMKKS
>Mature_186_residues
STLTSLPNILTLMRISIIPVFIMVFYFPFKWAHPTAAVLFAIASITDWLDGYLARKLEMMSHFGAFLDPVADKLLVSTSL
LLLVGAKDIDYITIPAIVIVGREIVISALREWMAEVGSRASVAVGYIGKVKTSLQMIALVLLLAFNPLVSWWGSLGFALL
YVSAILTIWSMVIYLAIAWPELMKKS

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=181, Percent_Identity=49.171270718232, Blast_Score=179, Evalue=1e-46,
Organism=Saccharomyces cerevisiae, GI6320059, Length=112, Percent_Identity=43.75, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 20711; Mature: 20580

Theoretical pI: Translated: 9.34; Mature: 9.34

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTLTSLPNILTLMRISIIPVFIMVFYFPFKWAHPTAAVLFAIASITDWLDGYLARKLEM
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
MSHFGAFLDPVADKLLVSTSLLLLVGAKDIDYITIPAIVIVGREIVISALREWMAEVGSR
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ASVAVGYIGKVKTSLQMIALVLLLAFNPLVSWWGSLGFALLYVSAILTIWSMVIYLAIAW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PELMKKS
HHHHCCC
>Mature Secondary Structure 
STLTSLPNILTLMRISIIPVFIMVFYFPFKWAHPTAAVLFAIASITDWLDGYLARKLEM
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
MSHFGAFLDPVADKLLVSTSLLLLVGAKDIDYITIPAIVIVGREIVISALREWMAEVGSR
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ASVAVGYIGKVKTSLQMIALVLLLAFNPLVSWWGSLGFALLYVSAILTIWSMVIYLAIAW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PELMKKS
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA