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The map label for this gene is rtcB [C]

Identifier: 54295045

GI number: 54295045

Start: 2427035

End: 2428465

Strand: Reverse

Name: rtcB [C]

Synonym: lpl2125

Alternate gene names: 54295045

Gene position: 2428465-2427035 (Counterclockwise)

Preceding gene: 54295046

Following gene: 54295044

Centisome position: 72.58

GC content: 43.54

Gene sequence:

>1431_bases
ATGGATTTAAGCCTCTTGAAAAAAATAAACGATTTTGAATGGCAAATACCTCAACATGGAAAGATGTTGGTGCCAGGAGT
TATTTTTGCGTCAGAACAGCTGATTCTTGATATGGATATGAAAGTTTACGAACAATTATCTAATGTTGCTACTTTGCCGG
GAATTGTTTCTGCTGCTTATGCTATGCCTGATGCGCATTGGGGATATGGTTTTCCGATTGGCGGTGTCGCTGCTTTTGAT
CCGGATGAGGGAGGGGTCATTTCAGCAGGAGGTGTTGGTTTTGACATTTCATGCGGGGTAAGGCTCTTATCGACCGGATT
GAAGCGAGATGAATTGGAGTCTGTCAAAGCCAGCCTTGCAGATGCTTTATTTGCACATATTCCAGCGGGAGTAGGCAGTA
GAAGCGGCATTCATTTAACGATAAAACAGCTCGATGATATGATGCGGGGGGGCGCACAATGGGCAGTAAAACAAGGATAT
GGTGAAGCTGCTGATTTAGAGCGTATCGAAGATCGTGGTTGTGTCGAAGGAGCTATCCCTGATTGTGTCTCTGAACAAGC
TAAAAAGCGCCAGAAAAATGAAATGGGCACCTTGGGTTCAGGTAACCATTATCTGGAAGTGCAGGAAGTCAGGCAAATCT
ACTGTTCCGATACAGCAACAGCTTTAAATTTGCATGAAGGAGATATTGTAGTGAGTATCCATTGTGGTTCCAGAGGATTG
GGGCATCAAATTGGTACAGATTACCTCCGTTCCATGGTTATTGAATCACAACATTATGGTATCAAGCTGGCGGATAGGGA
ATTGGCTTGTGCTCCTATTCATTCAAAGCTAGGGGAAAATTACCTGGGCGCTATGAGAGCAGGAATTAATTGTGCTTTAG
CCAACAGAGAAATCATCACTCATTTTATGCGCAATGTATTTCAGGATATTTTACCCCGCACTCAGATTGATCTCATCTAT
GACGTTTCTCACAATACTTGTAAAGAAGAATTTCATGAGGTAGATGGCAAGAAAAAGCGCTTATTTGTTCATCGAAAAGG
AGCAACTCGTGCCTTGGGCCCAGGCCATCCACAACTACCTAAAGCTGTTTCTCATATAGGCCAGCCTGTGATTATTGGAG
GGAGCATGGGAACAGGTTCCTATGTATTAGCAGGCGTCAAAGGTTCTGAGCATAAATCTTTTAGCTCGGCATGTCATGGA
GCAGGTCGCGCTATGAGTCGTCATCAGGCAATGAAGAAATGGAACGGGAAAGACATAGTAGATAAATTGGCTCAACAAGG
AATTTTAATTCGTAGCGGATCATACCGTGGGGTTGCTGAGGAAGCTCCGGGGGCTTATAAAGATGTTCATTCTATTGTCG
ATGCCGCTGAAATGTCGGGTTTGGCAAAAAAAGTTGCTAAATTAATTCCCATCATTTGTGTCAAAGGTTAA

Upstream 100 bases:

>100_bases
CTATACTGAATTAAAAGTATACAAAAATAATAATATTTGGATAGCTCAGTGTGTTGTTGATGTATAAACTCCTTAACAGG
AATTAATGTGGTGAACAGTG

Downstream 100 bases:

>100_bases
CAATCCATTGTTTATTGAGGTGAAAGGAGCAGCTTATAATTGTAAGGAATTTGTAAAAAAAATGAACTCAAAATAATTTT
CGATAAATTTTTAGACTAAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 476; Mature: 476

Protein sequence:

>476_residues
MDLSLLKKINDFEWQIPQHGKMLVPGVIFASEQLILDMDMKVYEQLSNVATLPGIVSAAYAMPDAHWGYGFPIGGVAAFD
PDEGGVISAGGVGFDISCGVRLLSTGLKRDELESVKASLADALFAHIPAGVGSRSGIHLTIKQLDDMMRGGAQWAVKQGY
GEAADLERIEDRGCVEGAIPDCVSEQAKKRQKNEMGTLGSGNHYLEVQEVRQIYCSDTATALNLHEGDIVVSIHCGSRGL
GHQIGTDYLRSMVIESQHYGIKLADRELACAPIHSKLGENYLGAMRAGINCALANREIITHFMRNVFQDILPRTQIDLIY
DVSHNTCKEEFHEVDGKKKRLFVHRKGATRALGPGHPQLPKAVSHIGQPVIIGGSMGTGSYVLAGVKGSEHKSFSSACHG
AGRAMSRHQAMKKWNGKDIVDKLAQQGILIRSGSYRGVAEEAPGAYKDVHSIVDAAEMSGLAKKVAKLIPIICVKG

Sequences:

>Translated_476_residues
MDLSLLKKINDFEWQIPQHGKMLVPGVIFASEQLILDMDMKVYEQLSNVATLPGIVSAAYAMPDAHWGYGFPIGGVAAFD
PDEGGVISAGGVGFDISCGVRLLSTGLKRDELESVKASLADALFAHIPAGVGSRSGIHLTIKQLDDMMRGGAQWAVKQGY
GEAADLERIEDRGCVEGAIPDCVSEQAKKRQKNEMGTLGSGNHYLEVQEVRQIYCSDTATALNLHEGDIVVSIHCGSRGL
GHQIGTDYLRSMVIESQHYGIKLADRELACAPIHSKLGENYLGAMRAGINCALANREIITHFMRNVFQDILPRTQIDLIY
DVSHNTCKEEFHEVDGKKKRLFVHRKGATRALGPGHPQLPKAVSHIGQPVIIGGSMGTGSYVLAGVKGSEHKSFSSACHG
AGRAMSRHQAMKKWNGKDIVDKLAQQGILIRSGSYRGVAEEAPGAYKDVHSIVDAAEMSGLAKKVAKLIPIICVKG
>Mature_476_residues
MDLSLLKKINDFEWQIPQHGKMLVPGVIFASEQLILDMDMKVYEQLSNVATLPGIVSAAYAMPDAHWGYGFPIGGVAAFD
PDEGGVISAGGVGFDISCGVRLLSTGLKRDELESVKASLADALFAHIPAGVGSRSGIHLTIKQLDDMMRGGAQWAVKQGY
GEAADLERIEDRGCVEGAIPDCVSEQAKKRQKNEMGTLGSGNHYLEVQEVRQIYCSDTATALNLHEGDIVVSIHCGSRGL
GHQIGTDYLRSMVIESQHYGIKLADRELACAPIHSKLGENYLGAMRAGINCALANREIITHFMRNVFQDILPRTQIDLIY
DVSHNTCKEEFHEVDGKKKRLFVHRKGATRALGPGHPQLPKAVSHIGQPVIIGGSMGTGSYVLAGVKGSEHKSFSSACHG
AGRAMSRHQAMKKWNGKDIVDKLAQQGILIRSGSYRGVAEEAPGAYKDVHSIVDAAEMSGLAKKVAKLIPIICVKG

Specific function: Unknown

COG id: COG1690

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0027 (rtcB) family [H]

Homologues:

Organism=Homo sapiens, GI7657015, Length=498, Percent_Identity=44.1767068273092, Blast_Score=389, Evalue=1e-108,
Organism=Escherichia coli, GI2367224, Length=449, Percent_Identity=29.1759465478842, Blast_Score=131, Evalue=8e-32,
Organism=Caenorhabditis elegans, GI17506665, Length=438, Percent_Identity=46.8036529680365, Blast_Score=379, Evalue=1e-105,
Organism=Drosophila melanogaster, GI24585217, Length=499, Percent_Identity=44.689378757515, Blast_Score=386, Evalue=1e-107,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001233 [H]

Pfam domain/function: PF01139 UPF0027 [H]

EC number: NA

Molecular weight: Translated: 51345; Mature: 51345

Theoretical pI: Translated: 7.47; Mature: 7.47

Prosite motif: PS01288 UPF0027

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLSLLKKINDFEWQIPQHGKMLVPGVIFASEQLILDMDMKVYEQLSNVATLPGIVSAAY
CCHHHHHHCCCCCEECCCCCCEEECEEEEECCCEEEECCHHHHHHHHHHHHHHHHHHHHH
AMPDAHWGYGFPIGGVAAFDPDEGGVISAGGVGFDISCGVRLLSTGLKRDELESVKASLA
HCCCCCCCCCCCCCCEEEECCCCCCEEECCCCCEEHHHHHHHHHCCCCHHHHHHHHHHHH
DALFAHIPAGVGSRSGIHLTIKQLDDMMRGGAQWAVKQGYGEAADLERIEDRGCVEGAIP
HHHHHHCCCCCCCCCCEEEEHHHHHHHHHCCHHHHHHCCCCCHHHHHHHHHCCCCCCCCC
DCVSEQAKKRQKNEMGTLGSGNHYLEVQEVRQIYCSDTATALNLHEGDIVVSIHCGSRGL
HHHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHCCCCEEEEEECCCEEEEEECCCCCC
GHQIGTDYLRSMVIESQHYGIKLADRELACAPIHSKLGENYLGAMRAGINCALANREIIT
CHHHHHHHHHHHHHCCCCCCEEEECCCCEEEHHHHHHCHHHHHHHHHCCEEEECCHHHHH
HFMRNVFQDILPRTQIDLIYDVSHNTCKEEFHEVDGKKKRLFVHRKGATRALGPGHPQLP
HHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCHH
KAVSHIGQPVIIGGSMGTGSYVLAGVKGSEHKSFSSACHGAGRAMSRHQAMKKWNGKDIV
HHHHHCCCCEEEECCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHH
DKLAQQGILIRSGSYRGVAEEAPGAYKDVHSIVDAAEMSGLAKKVAKLIPIICVKG
HHHHHCCEEEECCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECC
>Mature Secondary Structure
MDLSLLKKINDFEWQIPQHGKMLVPGVIFASEQLILDMDMKVYEQLSNVATLPGIVSAAY
CCHHHHHHCCCCCEECCCCCCEEECEEEEECCCEEEECCHHHHHHHHHHHHHHHHHHHHH
AMPDAHWGYGFPIGGVAAFDPDEGGVISAGGVGFDISCGVRLLSTGLKRDELESVKASLA
HCCCCCCCCCCCCCCEEEECCCCCCEEECCCCCEEHHHHHHHHHCCCCHHHHHHHHHHHH
DALFAHIPAGVGSRSGIHLTIKQLDDMMRGGAQWAVKQGYGEAADLERIEDRGCVEGAIP
HHHHHHCCCCCCCCCCEEEEHHHHHHHHHCCHHHHHHCCCCCHHHHHHHHHCCCCCCCCC
DCVSEQAKKRQKNEMGTLGSGNHYLEVQEVRQIYCSDTATALNLHEGDIVVSIHCGSRGL
HHHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHCCCCEEEEEECCCEEEEEECCCCCC
GHQIGTDYLRSMVIESQHYGIKLADRELACAPIHSKLGENYLGAMRAGINCALANREIIT
CHHHHHHHHHHHHHCCCCCCEEEECCCCEEEHHHHHHCHHHHHHHHHCCEEEECCHHHHH
HFMRNVFQDILPRTQIDLIYDVSHNTCKEEFHEVDGKKKRLFVHRKGATRALGPGHPQLP
HHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCHH
KAVSHIGQPVIIGGSMGTGSYVLAGVKGSEHKSFSSACHGAGRAMSRHQAMKKWNGKDIV
HHHHHCCCCEEEECCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHH
DKLAQQGILIRSGSYRGVAEEAPGAYKDVHSIVDAAEMSGLAKKVAKLIPIICVKG
HHHHHCCEEEECCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA