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The map label for this gene is pdxH [H]

Identifier: 54294989

GI number: 54294989

Start: 2330730

End: 2331317

Strand: Reverse

Name: pdxH [H]

Synonym: lpl2068

Alternate gene names: 54294989

Gene position: 2331317-2330730 (Counterclockwise)

Preceding gene: 54294990

Following gene: 54294987

Centisome position: 69.68

GC content: 39.46

Gene sequence:

>588_bases
ATGGCCAGAAACGACCCCATTGCCCTTCTAACAACATGGATTTCAGAGGAATTGGAAAGAGGAGCACCTAATCCACAACA
TGCCACATTATCTACGACAGGCAAAGATTCTATTCCCCATGGGCGTGTTATCGCCATTCGCGAAATCAATGAGCAAGGTT
TATTATTTTTTACCCAACGAGGAACCAGAAAGGTTGTCGAAATGACCTGTAATCCTATGGTATCTCTGACTTTTTGGTTT
GAGTTATTTGAAAGAGAAGTCATGATAGACGGTTCAGCCAGGCCATTATCGGAAAGCGAAAATCAAGCATACTGGGATAC
CTATCCGCCTTTCGCGCAAATCAGATTTCATAGTTATGCGCCTACTTCATCACACGTTATACCCAGCAAACAACTCATTG
AAAATAAAAGAAAAATATTGACTTCCCGGTTTCAAGATAAGTCATTGCCTATGAGTGAATATTATTGTGGTTTCAGAGTC
ATTCCCACACGCATGGTTTTTTATACTTATAGAACGGATGAATTGTCTGATGTCGTAGAATATTGTTTTATAAAAAACAA
TTGGGAGAAGAATCTGCTTTCTCCTTAA

Upstream 100 bases:

>100_bases
GCAAGTGAATTATGGCTCACAATATTTACCAACGTAATGAGACATCGCTAGTCCGTATCATTATTAACGCCAGAAAATAT
TTACAATAGGTATTCAAGTT

Downstream 100 bases:

>100_bases
TATCAATTTGTTTAAGCCTCATGATTGACGCAACAATATTTTTTTATTACATTCAATACCCATTGCAGCGGTTTATGATT
TGATAATCGTTTATGATAGT

Product: hypothetical protein

Products: NA

Alternate protein names: PNP/PMP oxidase; PNPOx; Pyridoxal 5'-phosphate synthase [H]

Number of amino acids: Translated: 195; Mature: 194

Protein sequence:

>195_residues
MARNDPIALLTTWISEELERGAPNPQHATLSTTGKDSIPHGRVIAIREINEQGLLFFTQRGTRKVVEMTCNPMVSLTFWF
ELFEREVMIDGSARPLSESENQAYWDTYPPFAQIRFHSYAPTSSHVIPSKQLIENKRKILTSRFQDKSLPMSEYYCGFRV
IPTRMVFYTYRTDELSDVVEYCFIKNNWEKNLLSP

Sequences:

>Translated_195_residues
MARNDPIALLTTWISEELERGAPNPQHATLSTTGKDSIPHGRVIAIREINEQGLLFFTQRGTRKVVEMTCNPMVSLTFWF
ELFEREVMIDGSARPLSESENQAYWDTYPPFAQIRFHSYAPTSSHVIPSKQLIENKRKILTSRFQDKSLPMSEYYCGFRV
IPTRMVFYTYRTDELSDVVEYCFIKNNWEKNLLSP
>Mature_194_residues
ARNDPIALLTTWISEELERGAPNPQHATLSTTGKDSIPHGRVIAIREINEQGLLFFTQRGTRKVVEMTCNPMVSLTFWFE
LFEREVMIDGSARPLSESENQAYWDTYPPFAQIRFHSYAPTSSHVIPSKQLIENKRKILTSRFQDKSLPMSEYYCGFRVI
PTRMVFYTYRTDELSDVVEYCFIKNNWEKNLLSP

Specific function: Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) [H]

COG id: COG0259

COG function: function code H; Pyridoxamine-phosphate oxidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pyridoxamine 5'-phosphate oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922498, Length=178, Percent_Identity=28.0898876404494, Blast_Score=90, Evalue=1e-18,
Organism=Escherichia coli, GI1787926, Length=191, Percent_Identity=28.7958115183246, Blast_Score=100, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI17553712, Length=171, Percent_Identity=26.3157894736842, Blast_Score=75, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6319509, Length=185, Percent_Identity=26.4864864864865, Blast_Score=76, Evalue=3e-15,
Organism=Drosophila melanogaster, GI45551845, Length=182, Percent_Identity=26.3736263736264, Blast_Score=73, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24644901, Length=182, Percent_Identity=26.3736263736264, Blast_Score=73, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000659
- InterPro:   IPR019740
- InterPro:   IPR019576
- InterPro:   IPR011576
- InterPro:   IPR012349
- InterPro:   IPR009002 [H]

Pfam domain/function: PF10590 PNPOx_C; PF01243 Pyridox_oxidase [H]

EC number: =1.4.3.5 [H]

Molecular weight: Translated: 22711; Mature: 22580

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARNDPIALLTTWISEELERGAPNPQHATLSTTGKDSIPHGRVIAIREINEQGLLFFTQR
CCCCCCHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCEEEEEEECCCCEEEEECC
GTRKVVEMTCNPMVSLTFWFELFEREVMIDGSARPLSESENQAYWDTYPPFAQIRFHSYA
CCCEEHHHHCCCHHHHHHHHHHHHHEEEECCCCCCCCCCCCCEECCCCCCCEEEEEECCC
PTSSHVIPSKQLIENKRKILTSRFQDKSLPMSEYYCGFRVIPTRMVFYTYRTDELSDVVE
CCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHCCCEEEECEEEEEEEECCHHHHHHHH
YCFIKNNWEKNLLSP
HHHHCCCCCCCCCCC
>Mature Secondary Structure 
ARNDPIALLTTWISEELERGAPNPQHATLSTTGKDSIPHGRVIAIREINEQGLLFFTQR
CCCCCHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCEEEEEEECCCCEEEEECC
GTRKVVEMTCNPMVSLTFWFELFEREVMIDGSARPLSESENQAYWDTYPPFAQIRFHSYA
CCCEEHHHHCCCHHHHHHHHHHHHHEEEECCCCCCCCCCCCCEECCCCCCCEEEEEECCC
PTSSHVIPSKQLIENKRKILTSRFQDKSLPMSEYYCGFRVIPTRMVFYTYRTDELSDVVE
CCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHCCCEEEECEEEEEEEECCHHHHHHHH
YCFIKNNWEKNLLSP
HHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA