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The map label for this gene is pilE1 [H]

Identifier: 54294802

GI number: 54294802

Start: 2104753

End: 2105166

Strand: Reverse

Name: pilE1 [H]

Synonym: lpl1879

Alternate gene names: 54294802

Gene position: 2105166-2104753 (Counterclockwise)

Preceding gene: 54294805

Following gene: 54294801

Centisome position: 62.92

GC content: 49.28

Gene sequence:

>414_bases
ATGAGACAAAAGGGTTTTACATTAATTGAATTGATGATAGTCGTAGCGATTATTGGCATTTTGGCAGCAATCGCTATACC
AGCCTATCAAGATTACACAATACGGGCTCGTGTCAGCGAGGGGTTACAGATGGCAAGCTCAGCCAAGCTTGCTGTGTCTG
AAACGGCTATCACGAACAATGCGTTACCTCCTACTCAGGCAGCAACGGGCTACGTGTCTCCCGCTGCCACGGCTAATGTG
TCAAACATTGCGATAGGCGCTAACGGTGTGATAACCATCACGTATACCCAAGCAGCAGGTGGCGGAACGATTGTTATGAC
CCCTGCGCTGGATGCCAACAACGGTGATGTCACCTGGAATTGTACTGGCGGTACCTTATTGGCTAAATACCGACCTGCCA
GTTGCAGACCATAA

Upstream 100 bases:

>100_bases
TAATTATTTAACATGTAAAATAATATGGGTTTAGGATATTGGCTGGTAGTTGGCATTATGCTTGCATTATACTAATGGAT
AGTTAACTATGGAGATGGTC

Downstream 100 bases:

>100_bases
TTAGGATAAATCAACTATTAAAACCGCCTTTCAATGGCGGTTTTTTATTTGTTTAAGCTATACCAATGAGTTATTGTCTG
ACAAGAATATCTAGAGAAAA

Product: hypothetical protein

Products: NA

Alternate protein names: MS11 antigen; Pilin [H]

Number of amino acids: Translated: 137; Mature: 137

Protein sequence:

>137_residues
MRQKGFTLIELMIVVAIIGILAAIAIPAYQDYTIRARVSEGLQMASSAKLAVSETAITNNALPPTQAATGYVSPAATANV
SNIAIGANGVITITYTQAAGGGTIVMTPALDANNGDVTWNCTGGTLLAKYRPASCRP

Sequences:

>Translated_137_residues
MRQKGFTLIELMIVVAIIGILAAIAIPAYQDYTIRARVSEGLQMASSAKLAVSETAITNNALPPTQAATGYVSPAATANV
SNIAIGANGVITITYTQAAGGGTIVMTPALDANNGDVTWNCTGGTLLAKYRPASCRP
>Mature_137_residues
MRQKGFTLIELMIVVAIIGILAAIAIPAYQDYTIRARVSEGLQMASSAKLAVSETAITNNALPPTQAATGYVSPAATANV
SNIAIGANGVITITYTQAAGGGTIVMTPALDANNGDVTWNCTGGTLLAKYRPASCRP

Specific function: This protein is the predominant Neisseria surface antigen, which allows adhesion of the bacterium to various host cells [H]

COG id: COG4969

COG function: function code NU; Tfp pilus assembly protein, major pilin PilA

Gene ontology:

Cell location: Fimbrium [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N-Me-Phe pilin family [H]

Homologues:

Organism=Escherichia coli, GI1786297, Length=123, Percent_Identity=40.650406504065, Blast_Score=85, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001082
- InterPro:   IPR012902
- InterPro:   IPR001120 [H]

Pfam domain/function: PF07963 N_methyl; PF00114 Pilin [H]

EC number: NA

Molecular weight: Translated: 14041; Mature: 14041

Theoretical pI: Translated: 8.70; Mature: 8.70

Prosite motif: PS00409 PROKAR_NTER_METHYL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQKGFTLIELMIVVAIIGILAAIAIPAYQDYTIRARVSEGLQMASSAKLAVSETAITNN
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHCHHHHCCCCEEEEEEEECCC
ALPPTQAATGYVSPAATANVSNIAIGANGVITITYTQAAGGGTIVMTPALDANNGDVTWN
CCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEEEEECCCCCEEEEECCEECCCCCEEEE
CTGGTLLAKYRPASCRP
ECCCEEEEEECCCCCCC
>Mature Secondary Structure
MRQKGFTLIELMIVVAIIGILAAIAIPAYQDYTIRARVSEGLQMASSAKLAVSETAITNN
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHCHHHHCCCCEEEEEEEECCC
ALPPTQAATGYVSPAATANVSNIAIGANGVITITYTQAAGGGTIVMTPALDANNGDVTWN
CCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEEEEECCCCCEEEEECCEECCCCCEEEE
CTGGTLLAKYRPASCRP
ECCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 6148752; 2872674; 1671354; 1348857; 6143785; 7477282; 10048019 [H]