| Definition | Legionella pneumophila str. Lens, complete genome. |
|---|---|
| Accession | NC_006369 |
| Length | 3,345,687 |
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The map label for this gene is lon [H]
Identifier: 54294746
GI number: 54294746
Start: 2038395
End: 2040845
Strand: Reverse
Name: lon [H]
Synonym: lpl1823
Alternate gene names: 54294746
Gene position: 2040845-2038395 (Counterclockwise)
Preceding gene: 54294747
Following gene: 54294745
Centisome position: 61.0
GC content: 39.53
Gene sequence:
>2451_bases ATGTCTAATGAAAATGAAATAATATCAAATGAGACTGTGAAATCTTCTGCTTTGCCTGTATTACCATTGAGGGACGTAGT CGTCTATCCGCATATGGTAATACCTCTCTTTGTTGGGCGTGGCAAGTCAATTAAAGCTCTTGAAGCTGCGATGATTGATA ATAAACAAATTTTTTTAGTTGCACAGCGTAAATCGGCGCATGATGATCCTGGCCCAGAAGATATCTATCAAGTGGGAACT GTATCCAGTGTTTTGCAATTGTTAAAGTTACCTGACGGAACTGTAAAAGTTCTTGTTGAAGGTGAGCAGCGTGCACGTGT CAAGGAGTATGCTCAGGATAAAGGTTACCTCGAAGCGACACTTGAATACATTGAGGAAGTTGGCTCAACAATTCAAGAGC AAGAAATTGGAATTCTAATGCGGTCCTTGATGTCGCAATTTGAACAATATATAAAGCTTAATAAGAAAATTCCACCAGAA GTCTTGTCACCATTGGCAGGAATAGAAGAGCCAGGTCGACTGGCAGATACCATTGCCGCACATTTAACGCTTAAAGTAGA TGATAAGCAAGAGTTGCTTGAAACTATGGATGTAGGAACTCGACTTGAGAAATTAATGGCGGCGATAGAAAATGAAATTG ATCTGTTACATGTTGAAAAACGTGTAAGAGGTCGAGTCAAACGTCAAATGGAAAAAAGCCAGAGAGAATACTATCTAAAC GAACAAATCAAAGCTATTCAGAAAGAATTAGGGGAAATGGGTGAGGAAGGCAATGAGATTGAACAATTGGAAAATTCAAT CAAAAAGGCCGGAATGCCGAAAGAAGCTAAAGAAAAATCATTAGCAGAGTTACATAAATTAAAAATGATGTCTCCCATGT CTGCTGAAGCAACTGTTATTCGTAATTATCTTGATTGGATGCTGATGGTCCCATGGAAGAAGCGGACCAAAATTCAGTTT GATTTACTAAAAGCAGAAAAGCTGCTCGATAAGGAGCATCATGGTCTGGAGCAGGTTAAAGAGCGTATCATCGAATATCT TGCTGTACAACAACGAGTAAAAAGATTGAAAGGACCGATATTGTGTTTAGTAGGCCCTCCGGGAGTAGGTAAAACTTCTC TTGGACAATCTATCGCCAATGCTACTGGAAGAACTTTCATACGCATCGCTCTGGGTGGGGTAAGAGATGAAGCAGAAATT CGTGGTCATCGAAGAACATATATAGGTTCCATGCCAGGTAAAATTATCCAAAAATTATGCAAGGCAGGAGTTAAAAATCC TCTTATCATGCTGGATGAAGTAGATAAGATGGCAATGGATTTTCGTGGTGATCCGGCATCGGCATTACTGGAAGTATTGG ATCCTGAACAGAACCATACATTTAGTGATCATTACTTGGAAGTTGATTATGACTTGAGTGATGTTATGTTTATTGCAACT GCCAATTCGCTAGAAATTCCAGCCCCGTTATTGGATAGAATGGAAGTTATTCGCTTGCCTGGATATACTGAGGACGAAAA AGTCAGTATTGCTGAAAAATATTTGGTTCCCAAACAAATGCTGCTAAATGGTTTAACCAATGAAGAAATCCATATTAGCG AAGGGGCTATTAGAGATATCATACGTTATTATACTCGAGAGGCTGGAGTACGTAATCTTGAAAGGGATATAGCGAGTATA TGCAGAAAAGTTGTTAAAGAAATACTCTCAAGCAAAAAAGGAAAAAAAGGAAAAACAATCAGTATAACTGTTAGCAACAT TACTAAGTATTTGGGCGTTAAAAAGTATCGTTATGGATTAGCTGAGCAATATGATCAGATAGGTCAAGTCACTGGTTTAG CCTGGACAAGTGTTGGAGGTGAACTTCTGACTATAGAAGCATCCATTATGCCAGGTAAGGGTAAAGTTACTCATACTGGT CAGCTTGGTGAGGTAATGCAAGAATCTATCCATGCAGCTATGACGGTAGTAAGAAGCCGCGCTAAAGCTTTTGGGTTGCC AGATGATTTTTATGAGAAACATGATTTTCATGTTCATGTACCAGAAGGTGCAACACCCAAAGATGGCCCAAGCGCTGGTA TAGGAATGTGCACGGTACTAGTCTCCATAGTAACACAAATCCCAGTTAAGGCAGATGTCGCCATGACCGGTGAAATTACT CTGCGTGGGCAAGTTTTACCAATTGGAGGATTAAAAGAAAAATTGCTGGCTGCACATCGTGGTGGAATCAAGCATGTCAT TATCCCCGAGGAGAATGTAAAAGACCTTGAGGAAATCCCTGATAATGTGCTCCGTAAGCTGACAATTCATCCTGTTAACA CCATTGAACAGGTTTTGGAACTGGCTTTGCAACGCAATCCATGGGTGGAAGAGCCAACAAATATACAACCTGGCACTATA TTGAATAAAAAATCAAAAAAAATTAAAAATAATGATTTACACGCACATTAA
Upstream 100 bases:
>100_bases CTCATATTACGAATTGTTCACCAGCACCAATATCTGTATACTCGTAAGAAATAGTATAAGAAACTATAACCAAGAAATTT TCCTTTGAATAAGGGTCATT
Downstream 100 bases:
>100_bases TACAGAGTATATTTCTCTTCGTGGCCCGCTACTGGCGGGCTCTGCAAGGATGTACGAACTTGACTGGAGCAGTTGAATCT GTTTAAATCAGCTCCGGAAT
Product: hypothetical protein
Products: NA
Alternate protein names: ATP-dependent protease La [H]
Number of amino acids: Translated: 816; Mature: 815
Protein sequence:
>816_residues MSNENEIISNETVKSSALPVLPLRDVVVYPHMVIPLFVGRGKSIKALEAAMIDNKQIFLVAQRKSAHDDPGPEDIYQVGT VSSVLQLLKLPDGTVKVLVEGEQRARVKEYAQDKGYLEATLEYIEEVGSTIQEQEIGILMRSLMSQFEQYIKLNKKIPPE VLSPLAGIEEPGRLADTIAAHLTLKVDDKQELLETMDVGTRLEKLMAAIENEIDLLHVEKRVRGRVKRQMEKSQREYYLN EQIKAIQKELGEMGEEGNEIEQLENSIKKAGMPKEAKEKSLAELHKLKMMSPMSAEATVIRNYLDWMLMVPWKKRTKIQF DLLKAEKLLDKEHHGLEQVKERIIEYLAVQQRVKRLKGPILCLVGPPGVGKTSLGQSIANATGRTFIRIALGGVRDEAEI RGHRRTYIGSMPGKIIQKLCKAGVKNPLIMLDEVDKMAMDFRGDPASALLEVLDPEQNHTFSDHYLEVDYDLSDVMFIAT ANSLEIPAPLLDRMEVIRLPGYTEDEKVSIAEKYLVPKQMLLNGLTNEEIHISEGAIRDIIRYYTREAGVRNLERDIASI CRKVVKEILSSKKGKKGKTISITVSNITKYLGVKKYRYGLAEQYDQIGQVTGLAWTSVGGELLTIEASIMPGKGKVTHTG QLGEVMQESIHAAMTVVRSRAKAFGLPDDFYEKHDFHVHVPEGATPKDGPSAGIGMCTVLVSIVTQIPVKADVAMTGEIT LRGQVLPIGGLKEKLLAAHRGGIKHVIIPEENVKDLEEIPDNVLRKLTIHPVNTIEQVLELALQRNPWVEEPTNIQPGTI LNKKSKKIKNNDLHAH
Sequences:
>Translated_816_residues MSNENEIISNETVKSSALPVLPLRDVVVYPHMVIPLFVGRGKSIKALEAAMIDNKQIFLVAQRKSAHDDPGPEDIYQVGT VSSVLQLLKLPDGTVKVLVEGEQRARVKEYAQDKGYLEATLEYIEEVGSTIQEQEIGILMRSLMSQFEQYIKLNKKIPPE VLSPLAGIEEPGRLADTIAAHLTLKVDDKQELLETMDVGTRLEKLMAAIENEIDLLHVEKRVRGRVKRQMEKSQREYYLN EQIKAIQKELGEMGEEGNEIEQLENSIKKAGMPKEAKEKSLAELHKLKMMSPMSAEATVIRNYLDWMLMVPWKKRTKIQF DLLKAEKLLDKEHHGLEQVKERIIEYLAVQQRVKRLKGPILCLVGPPGVGKTSLGQSIANATGRTFIRIALGGVRDEAEI RGHRRTYIGSMPGKIIQKLCKAGVKNPLIMLDEVDKMAMDFRGDPASALLEVLDPEQNHTFSDHYLEVDYDLSDVMFIAT ANSLEIPAPLLDRMEVIRLPGYTEDEKVSIAEKYLVPKQMLLNGLTNEEIHISEGAIRDIIRYYTREAGVRNLERDIASI CRKVVKEILSSKKGKKGKTISITVSNITKYLGVKKYRYGLAEQYDQIGQVTGLAWTSVGGELLTIEASIMPGKGKVTHTG QLGEVMQESIHAAMTVVRSRAKAFGLPDDFYEKHDFHVHVPEGATPKDGPSAGIGMCTVLVSIVTQIPVKADVAMTGEIT LRGQVLPIGGLKEKLLAAHRGGIKHVIIPEENVKDLEEIPDNVLRKLTIHPVNTIEQVLELALQRNPWVEEPTNIQPGTI LNKKSKKIKNNDLHAH >Mature_815_residues SNENEIISNETVKSSALPVLPLRDVVVYPHMVIPLFVGRGKSIKALEAAMIDNKQIFLVAQRKSAHDDPGPEDIYQVGTV SSVLQLLKLPDGTVKVLVEGEQRARVKEYAQDKGYLEATLEYIEEVGSTIQEQEIGILMRSLMSQFEQYIKLNKKIPPEV LSPLAGIEEPGRLADTIAAHLTLKVDDKQELLETMDVGTRLEKLMAAIENEIDLLHVEKRVRGRVKRQMEKSQREYYLNE QIKAIQKELGEMGEEGNEIEQLENSIKKAGMPKEAKEKSLAELHKLKMMSPMSAEATVIRNYLDWMLMVPWKKRTKIQFD LLKAEKLLDKEHHGLEQVKERIIEYLAVQQRVKRLKGPILCLVGPPGVGKTSLGQSIANATGRTFIRIALGGVRDEAEIR GHRRTYIGSMPGKIIQKLCKAGVKNPLIMLDEVDKMAMDFRGDPASALLEVLDPEQNHTFSDHYLEVDYDLSDVMFIATA NSLEIPAPLLDRMEVIRLPGYTEDEKVSIAEKYLVPKQMLLNGLTNEEIHISEGAIRDIIRYYTREAGVRNLERDIASIC RKVVKEILSSKKGKKGKTISITVSNITKYLGVKKYRYGLAEQYDQIGQVTGLAWTSVGGELLTIEASIMPGKGKVTHTGQ LGEVMQESIHAAMTVVRSRAKAFGLPDDFYEKHDFHVHVPEGATPKDGPSAGIGMCTVLVSIVTQIPVKADVAMTGEITL RGQVLPIGGLKEKLLAAHRGGIKHVIIPEENVKDLEEIPDNVLRKLTIHPVNTIEQVLELALQRNPWVEEPTNIQPGTIL NKKSKKIKNNDLHAH
Specific function: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced
COG id: COG0466
COG function: function code O; ATP-dependent Lon protease, bacterial type
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 Lon domain [H]
Homologues:
Organism=Homo sapiens, GI31377667, Length=764, Percent_Identity=40.0523560209424, Blast_Score=530, Evalue=1e-150, Organism=Homo sapiens, GI21396489, Length=667, Percent_Identity=40.1799100449775, Blast_Score=496, Evalue=1e-140, Organism=Escherichia coli, GI1786643, Length=770, Percent_Identity=68.8311688311688, Blast_Score=1068, Evalue=0.0, Organism=Caenorhabditis elegans, GI17505831, Length=660, Percent_Identity=40.3030303030303, Blast_Score=473, Evalue=1e-133, Organism=Caenorhabditis elegans, GI17556486, Length=542, Percent_Identity=41.8819188191882, Blast_Score=438, Evalue=1e-123, Organism=Saccharomyces cerevisiae, GI6319449, Length=694, Percent_Identity=40.2017291066282, Blast_Score=504, Evalue=1e-143, Organism=Drosophila melanogaster, GI24666867, Length=629, Percent_Identity=42.6073131955485, Blast_Score=499, Evalue=1e-141, Organism=Drosophila melanogaster, GI221513036, Length=629, Percent_Identity=42.6073131955485, Blast_Score=499, Evalue=1e-141,
Paralogues:
None
Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003593 - InterPro: IPR003959 - InterPro: IPR008269 - InterPro: IPR004815 - InterPro: IPR003111 - InterPro: IPR001984 - InterPro: IPR015947 - InterPro: IPR020568 [H]
Pfam domain/function: PF00004 AAA; PF02190 LON; PF05362 Lon_C [H]
EC number: =3.4.21.53 [H]
Molecular weight: Translated: 91214; Mature: 91083
Theoretical pI: Translated: 7.11; Mature: 7.11
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.5 %Cys (Translated Protein) 3.3 %Met (Translated Protein) 3.8 %Cys+Met (Translated Protein) 0.5 %Cys (Mature Protein) 3.2 %Met (Mature Protein) 3.7 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSNENEIISNETVKSSALPVLPLRDVVVYPHMVIPLFVGRGKSIKALEAAMIDNKQIFLV CCCCCCCCCCCCHHHCCCCCCCHHHHHHCCHHHHHHHHCCCCCHHHHHHHHCCCCEEEEE AQRKSAHDDPGPEDIYQVGTVSSVLQLLKLPDGTVKVLVEGEQRARVKEYAQDKGYLEAT EECCCCCCCCCHHHHHHHCCHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHCCCHHHHH LEYIEEVGSTIQEQEIGILMRSLMSQFEQYIKLNKKIPPEVLSPLAGIEEPGRLADTIAA HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHH HLTLKVDDKQELLETMDVGTRLEKLMAAIENEIDLLHVEKRVRGRVKRQMEKSQREYYLN HEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH EQIKAIQKELGEMGEEGNEIEQLENSIKKAGMPKEAKEKSLAELHKLKMMSPMSAEATVI HHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHH RNYLDWMLMVPWKKRTKIQFDLLKAEKLLDKEHHGLEQVKERIIEYLAVQQRVKRLKGPI HHHHHHHEECCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCE LCLVGPPGVGKTSLGQSIANATGRTFIRIALGGVRDEAEIRGHRRTYIGSMPGKIIQKLC EEEECCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCHHHHCCCHHHHCCCCCHHHHHHHH KAGVKNPLIMLDEVDKMAMDFRGDPASALLEVLDPEQNHTFSDHYLEVDYDLSDVMFIAT HCCCCCCEEEHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCEEEEECCCCCEEEEEE ANSLEIPAPLLDRMEVIRLPGYTEDEKVSIAEKYLVPKQMLLNGLTNEEIHISEGAIRDI CCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCHHHHHCCCCCCCEEECCHHHHHH IRYYTREAGVRNLERDIASICRKVVKEILSSKKGKKGKTISITVSNITKYLGVKKYRYGL HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHHH AEQYDQIGQVTGLAWTSVGGELLTIEASIMPGKGKVTHTGQLGEVMQESIHAAMTVVRSR HHHHHHHHHHHCCCHHCCCCEEEEEEEEEECCCCCEEECCHHHHHHHHHHHHHHHHHHHH AKAFGLPDDFYEKHDFHVHVPEGATPKDGPSAGIGMCTVLVSIVTQIPVKADVAMTGEIT HHHCCCCHHHHCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECEEE LRGQVLPIGGLKEKLLAAHRGGIKHVIIPEENVKDLEEIPDNVLRKLTIHPVNTIEQVLE EEEEEEECCCHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHEECCCHHHHHHHHH LALQRNPWVEEPTNIQPGTILNKKSKKIKNNDLHAH HHHHCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCC >Mature Secondary Structure SNENEIISNETVKSSALPVLPLRDVVVYPHMVIPLFVGRGKSIKALEAAMIDNKQIFLV CCCCCCCCCCCHHHCCCCCCCHHHHHHCCHHHHHHHHCCCCCHHHHHHHHCCCCEEEEE AQRKSAHDDPGPEDIYQVGTVSSVLQLLKLPDGTVKVLVEGEQRARVKEYAQDKGYLEAT EECCCCCCCCCHHHHHHHCCHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHCCCHHHHH LEYIEEVGSTIQEQEIGILMRSLMSQFEQYIKLNKKIPPEVLSPLAGIEEPGRLADTIAA HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHH HLTLKVDDKQELLETMDVGTRLEKLMAAIENEIDLLHVEKRVRGRVKRQMEKSQREYYLN HEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH EQIKAIQKELGEMGEEGNEIEQLENSIKKAGMPKEAKEKSLAELHKLKMMSPMSAEATVI HHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHH RNYLDWMLMVPWKKRTKIQFDLLKAEKLLDKEHHGLEQVKERIIEYLAVQQRVKRLKGPI HHHHHHHEECCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCE LCLVGPPGVGKTSLGQSIANATGRTFIRIALGGVRDEAEIRGHRRTYIGSMPGKIIQKLC EEEECCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCHHHHCCCHHHHCCCCCHHHHHHHH KAGVKNPLIMLDEVDKMAMDFRGDPASALLEVLDPEQNHTFSDHYLEVDYDLSDVMFIAT HCCCCCCEEEHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCEEEEECCCCCEEEEEE ANSLEIPAPLLDRMEVIRLPGYTEDEKVSIAEKYLVPKQMLLNGLTNEEIHISEGAIRDI CCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCHHHHHCCCCCCCEEECCHHHHHH IRYYTREAGVRNLERDIASICRKVVKEILSSKKGKKGKTISITVSNITKYLGVKKYRYGL HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHHH AEQYDQIGQVTGLAWTSVGGELLTIEASIMPGKGKVTHTGQLGEVMQESIHAAMTVVRSR HHHHHHHHHHHCCCHHCCCCEEEEEEEEEECCCCCEEECCHHHHHHHHHHHHHHHHHHHH AKAFGLPDDFYEKHDFHVHVPEGATPKDGPSAGIGMCTVLVSIVTQIPVKADVAMTGEIT HHHCCCCHHHHCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECEEE LRGQVLPIGGLKEKLLAAHRGGIKHVIIPEENVKDLEEIPDNVLRKLTIHPVNTIEQVLE EEEEEEECCCHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHEECCCHHHHHHHHH LALQRNPWVEEPTNIQPGTILNKKSKKIKNNDLHAH HHHHCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 8981986; 12620739 [H]