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The map label for this gene is cpnA [H]

Identifier: 54294085

GI number: 54294085

Start: 1278976

End: 1279860

Strand: Reverse

Name: cpnA [H]

Synonym: lpl1149

Alternate gene names: 54294085

Gene position: 1279860-1278976 (Counterclockwise)

Preceding gene: 54294086

Following gene: 54294084

Centisome position: 38.25

GC content: 37.63

Gene sequence:

>885_bases
ATGGCGAAGACGGATAAAAAAATAGTGGTGGTCACAGGTTGTTCAAAAACATCCGGCGTAGGATATAATCTTGTATGTGA
AATGCTAAAGCGCGGGCATCAAGTCATTGCAACAGTGAGAAATCTTGAAACAAGCCAAATTAACAAAGCAAACCTCCTAA
ACTCCAGCAATTTGGATGTAAAAATATTGGATCTTTGCGATGAAAATTCAATTGACCGCTTTATTAAAGAAGTCTTAAGT
CAATATCAATACATTGACGCCTTGGTTAACAATGCTGCTAATGTGGCTATTGGCCCTGTTGAAAGCGCAACCACTCAAGA
TGTATTAACAACTTTTCAAACCAAAGTATTTGGCCCATTGTCTTTAATCAGGGGATTCATCCCTGTAATGAGAGAAAGGA
AAAAAGGTTTATTAACAACAACATCCACGATTTTTACCTCTGTTCCCGTTAGTATTCCAGGTGTCGCAATCTATTTTTCA
GCACTCGCAGCATTTGAACGATTACAAGAATCCTTGGCGATTGAGTTAGCCCCGTGGAATATCAAAGTAGTTAATTTCCA
ACCTGGGCCAATTGCGACAGAATTGACCCGATTTGAAGGCTCTCGCGCTGATATTGTTGAGAAATACTATAAAAACTTTA
CTGAACAAGCATATCAATGGTTCCATCAGAATACTGTTTTTCAAAATGCAGCGGAAGTAGCCAAGGTATTTGCTGAAGTT
ATTGATATGGAGAATCCTGATTTATGCTATCAAAGCAATCTTTTTGGAAAAGAATTTGTTGCAAAAAATAAAAAAGATAC
AACAGGGCGTGAGGGAATGGACAAACTTCTGGAGCATTTCAAAAATTTACCCCATGACAATCCTGATGATTGGAAAATTC
AATAA

Upstream 100 bases:

>100_bases
AAACCTTTTTTAACAAAGAGATTGGGTTTTTTCGTAAGTTCTGAATAAATAAAAGGGCTATACTCAGTTTATTACTCTAA
AAGATCATTAGGATAGAGGC

Downstream 100 bases:

>100_bases
ATGATTTACTGGATAAAGTCATACTATCCGCCGCGAAATCTCTGTGCATAAGCAAAAAATCCTCAGTGGCTTGACCTGAG
CATTGGATTATGTTGATAGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 294; Mature: 293

Protein sequence:

>294_residues
MAKTDKKIVVVTGCSKTSGVGYNLVCEMLKRGHQVIATVRNLETSQINKANLLNSSNLDVKILDLCDENSIDRFIKEVLS
QYQYIDALVNNAANVAIGPVESATTQDVLTTFQTKVFGPLSLIRGFIPVMRERKKGLLTTTSTIFTSVPVSIPGVAIYFS
ALAAFERLQESLAIELAPWNIKVVNFQPGPIATELTRFEGSRADIVEKYYKNFTEQAYQWFHQNTVFQNAAEVAKVFAEV
IDMENPDLCYQSNLFGKEFVAKNKKDTTGREGMDKLLEHFKNLPHDNPDDWKIQ

Sequences:

>Translated_294_residues
MAKTDKKIVVVTGCSKTSGVGYNLVCEMLKRGHQVIATVRNLETSQINKANLLNSSNLDVKILDLCDENSIDRFIKEVLS
QYQYIDALVNNAANVAIGPVESATTQDVLTTFQTKVFGPLSLIRGFIPVMRERKKGLLTTTSTIFTSVPVSIPGVAIYFS
ALAAFERLQESLAIELAPWNIKVVNFQPGPIATELTRFEGSRADIVEKYYKNFTEQAYQWFHQNTVFQNAAEVAKVFAEV
IDMENPDLCYQSNLFGKEFVAKNKKDTTGREGMDKLLEHFKNLPHDNPDDWKIQ
>Mature_293_residues
AKTDKKIVVVTGCSKTSGVGYNLVCEMLKRGHQVIATVRNLETSQINKANLLNSSNLDVKILDLCDENSIDRFIKEVLSQ
YQYIDALVNNAANVAIGPVESATTQDVLTTFQTKVFGPLSLIRGFIPVMRERKKGLLTTTSTIFTSVPVSIPGVAIYFSA
LAAFERLQESLAIELAPWNIKVVNFQPGPIATELTRFEGSRADIVEKYYKNFTEQAYQWFHQNTVFQNAAEVAKVFAEVI
DMENPDLCYQSNLFGKEFVAKNKKDTTGREGMDKLLEHFKNLPHDNPDDWKIQ

Specific function: Reduces cyclopentanol to cyclopentanone. The enzyme also shows considerable activity toward cyclohexanol [H]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI7657478, Length=282, Percent_Identity=26.9503546099291, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI223718074, Length=263, Percent_Identity=28.1368821292776, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI7706318, Length=250, Percent_Identity=30.4, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI119392083, Length=232, Percent_Identity=25.4310344827586, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI20149619, Length=211, Percent_Identity=26.0663507109005, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI1786701, Length=196, Percent_Identity=28.5714285714286, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1787820, Length=210, Percent_Identity=30.4761904761905, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1786812, Length=210, Percent_Identity=24.2857142857143, Blast_Score=64, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17562910, Length=236, Percent_Identity=26.6949152542373, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI193210355, Length=259, Percent_Identity=26.6409266409266, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6322067, Length=194, Percent_Identity=30.4123711340206, Blast_Score=71, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21358495, Length=196, Percent_Identity=30.6122448979592, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21357041, Length=216, Percent_Identity=28.2407407407407, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI28571526, Length=219, Percent_Identity=25.1141552511416, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24643142, Length=189, Percent_Identity=28.5714285714286, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.163 [H]

Molecular weight: Translated: 32995; Mature: 32864

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKTDKKIVVVTGCSKTSGVGYNLVCEMLKRGHQVIATVRNLETSQINKANLLNSSNLDV
CCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHCCHHHCCCCCCCCE
KILDLCDENSIDRFIKEVLSQYQYIDALVNNAANVAIGPVESATTQDVLTTFQTKVFGPL
EEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHCCHH
SLIRGFIPVMRERKKGLLTTTSTIFTSVPVSIPGVAIYFSALAAFERLQESLAIELAPWN
HHHHHHHHHHHHHHCCCEEEHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHEEEECCCE
IKVVNFQPGPIATELTRFEGSRADIVEKYYKNFTEQAYQWFHQNTVFQNAAEVAKVFAEV
EEEEEECCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IDMENPDLCYQSNLFGKEFVAKNKKDTTGREGMDKLLEHFKNLPHDNPDDWKIQ
HCCCCCCCHHHCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
AKTDKKIVVVTGCSKTSGVGYNLVCEMLKRGHQVIATVRNLETSQINKANLLNSSNLDV
CCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHCCHHHCCCCCCCCE
KILDLCDENSIDRFIKEVLSQYQYIDALVNNAANVAIGPVESATTQDVLTTFQTKVFGPL
EEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHCCHH
SLIRGFIPVMRERKKGLLTTTSTIFTSVPVSIPGVAIYFSALAAFERLQESLAIELAPWN
HHHHHHHHHHHHHHCCCEEEHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHEEEECCCE
IKVVNFQPGPIATELTRFEGSRADIVEKYYKNFTEQAYQWFHQNTVFQNAAEVAKVFAEV
EEEEEECCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IDMENPDLCYQSNLFGKEFVAKNKKDTTGREGMDKLLEHFKNLPHDNPDDWKIQ
HCCCCCCCHHHCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12406764 [H]