Click here to switch to the map view.

The map label for this gene is adc [H]

Identifier: 54293655

GI number: 54293655

Start: 795735

End: 796499

Strand: Direct

Name: adc [H]

Synonym: lpl0708

Alternate gene names: 54293655

Gene position: 795735-796499 (Clockwise)

Preceding gene: 54293654

Following gene: 54293656

Centisome position: 23.78

GC content: 39.22

Gene sequence:

>765_bases
ATGGACAAGTATCTTTCAGCAAATTCTCTAGAAGGGGTTATCGATAATGAATTTAACATGCCAGCTCCGCGTTGGTTAAA
TACTTACCCGGCTGGCCCATATCGATTTATTAATCGTGAATTTTTTATTATTGCTTATGAAACCGATCCGGATCTTTTGC
AAGCTATTTTACCTCCTGATATGGAATTATTGGAGCCGGTAGTCAAATTTGAATTTATACGTATGCCTGATTCAACAGGA
TTTGGTGATTACACTGAGTCAGGGCAAGTGGTACCTGTGAGATATAAAGGAGAAGAGGGCGGATTTACTATTTCAATGTT
TCTTGATTGTCATGCCCCTATTGCTGGTGGCCGAGAAATATGGGGTTTTCCAAAGAAGCTGGCCAAACCCAAATTGTTTG
TTGAAGAAGACACGCTCATTGGCATTCTTAAGTATGGGAGTATTGATATTGCCATCGCAACTATGGGATATAAACATCGT
CCGCTGGATGCGGAAAAGGTATTGGAATCCGTTAAAAAGCCTGTATTTTTACTTAAAAACATTCCTAATGTAGATGGAAC
TCCTCTAGTGAATCAGTTGACCAAAACTTATTTGACTGATATTACAGTGAAAGGAGCATGGACCGGACCAGGTAGCTTGG
AGCTTCATCCTCATGCACTGGCTCCTATCTCTAATCTTTATATTAAAAAAATTGTATCTGTTTCACATTTTATTACTGAT
TTGACCTTACCGTATGGAGAGGTTGTTGCCGATTATTTGGCCTAA

Upstream 100 bases:

>100_bases
TGCTGATTACCGATGATTCATTGAATAAAAAAAATAAATCAGGGACGAGCGAGGTTTAGGGCTCATTGAAGATAATAAGG
AAATACAAAAGGAGTGATTA

Downstream 100 bases:

>100_bases
AATAAAAAGCGACTCCTAAAAATGGCAGGAAAATCATATGGATAAACGTCCGATACAAAACACGGCCGTCATTGCAGCTG
CTTTGGGGGCTGCTCTTGCT

Product: acetoacetate decarboxylase

Products: NA

Alternate protein names: AAD; ADC [H]

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MDKYLSANSLEGVIDNEFNMPAPRWLNTYPAGPYRFINREFFIIAYETDPDLLQAILPPDMELLEPVVKFEFIRMPDSTG
FGDYTESGQVVPVRYKGEEGGFTISMFLDCHAPIAGGREIWGFPKKLAKPKLFVEEDTLIGILKYGSIDIAIATMGYKHR
PLDAEKVLESVKKPVFLLKNIPNVDGTPLVNQLTKTYLTDITVKGAWTGPGSLELHPHALAPISNLYIKKIVSVSHFITD
LTLPYGEVVADYLA

Sequences:

>Translated_254_residues
MDKYLSANSLEGVIDNEFNMPAPRWLNTYPAGPYRFINREFFIIAYETDPDLLQAILPPDMELLEPVVKFEFIRMPDSTG
FGDYTESGQVVPVRYKGEEGGFTISMFLDCHAPIAGGREIWGFPKKLAKPKLFVEEDTLIGILKYGSIDIAIATMGYKHR
PLDAEKVLESVKKPVFLLKNIPNVDGTPLVNQLTKTYLTDITVKGAWTGPGSLELHPHALAPISNLYIKKIVSVSHFITD
LTLPYGEVVADYLA
>Mature_254_residues
MDKYLSANSLEGVIDNEFNMPAPRWLNTYPAGPYRFINREFFIIAYETDPDLLQAILPPDMELLEPVVKFEFIRMPDSTG
FGDYTESGQVVPVRYKGEEGGFTISMFLDCHAPIAGGREIWGFPKKLAKPKLFVEEDTLIGILKYGSIDIAIATMGYKHR
PLDAEKVLESVKKPVFLLKNIPNVDGTPLVNQLTKTYLTDITVKGAWTGPGSLELHPHALAPISNLYIKKIVSVSHFITD
LTLPYGEVVADYLA

Specific function: Catalyzes the conversion of acetoacetate to acetone and carbon dioxide [H]

COG id: COG4689

COG function: function code Q; Acetoacetate decarboxylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ADC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010451 [H]

Pfam domain/function: PF06314 ADC [H]

EC number: =4.1.1.4 [H]

Molecular weight: Translated: 28368; Mature: 28368

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKYLSANSLEGVIDNEFNMPAPRWLNTYPAGPYRFINREFFIIAYETDPDLLQAILPPD
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCEEEEEEECCCHHHHHHHCCCC
MELLEPVVKFEFIRMPDSTGFGDYTESGQVVPVRYKGEEGGFTISMFLDCHAPIAGGREI
HHHHHHHHHEEEEECCCCCCCCCCCCCCCEEEEEEECCCCCEEEEEEEEECCCCCCCCHH
WGFPKKLAKPKLFVEEDTLIGILKYGSIDIAIATMGYKHRPLDAEKVLESVKKPVFLLKN
CCCHHHHCCCEEEEECCCEEEEEEECCEEEEEEECCCCCCCCCHHHHHHHHHCCEEEECC
IPNVDGTPLVNQLTKTYLTDITVKGAWTGPGSLELHPHALAPISNLYIKKIVSVSHFITD
CCCCCCCHHHHHHHHHHHHEEEEEEEECCCCCEEECCHHHCHHHHHHHHHHHHHHHHHHH
LTLPYGEVVADYLA
CCCCHHHHHHHHHC
>Mature Secondary Structure
MDKYLSANSLEGVIDNEFNMPAPRWLNTYPAGPYRFINREFFIIAYETDPDLLQAILPPD
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCEEEEEEECCCHHHHHHHCCCC
MELLEPVVKFEFIRMPDSTGFGDYTESGQVVPVRYKGEEGGFTISMFLDCHAPIAGGREI
HHHHHHHHHEEEEECCCCCCCCCCCCCCCEEEEEEECCCCCEEEEEEEEECCCCCCCCHH
WGFPKKLAKPKLFVEEDTLIGILKYGSIDIAIATMGYKHRPLDAEKVLESVKKPVFLLKN
CCCHHHHCCCEEEEECCCEEEEEEECCEEEEEEECCCCCCCCCHHHHHHHHHCCEEEECC
IPNVDGTPLVNQLTKTYLTDITVKGAWTGPGSLELHPHALAPISNLYIKKIVSVSHFITD
CCCCCCCHHHHHHHHHHHHEEEEEEEECCCCCEEECCHHHCHHHHHHHHHHHHHHHHHHH
LTLPYGEVVADYLA
CCCCHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA