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The map label for this gene is secY [H]

Identifier: 54293341

GI number: 54293341

Start: 440947

End: 442281

Strand: Direct

Name: secY [H]

Synonym: lpl0389

Alternate gene names: 54293341

Gene position: 440947-442281 (Clockwise)

Preceding gene: 54293340

Following gene: 54293342

Centisome position: 13.18

GC content: 36.7

Gene sequence:

>1335_bases
GTGACTATGAAAAACCAAAAGCATAACGGTAGTAAGCCTCGAGGTGGATTAGCCGAACTAAAGTCAAGACTGATGTTTGT
TGTTCTCGGCATATTAGTTTACCGATTAGGTGCACATATACCTGTTCCAGGATTAGATCCTGCAAAATTAGCTAATTTTT
TTAGTGAACAGCAAAACACTATATTTGGCTTGTTTAATATGTTTTCTGGTGGAGCCCTGTCTCGTGTAACAGTGTTTGCA
ATTGGTATTATGCCTTATATTTCTGCATCAATTATAATTCAACTGTTTTCTGTAGTTTCTCCCAAGCTGGAGCAGCTAAA
GAAAGAGGGAGAATCAGGTCGTAGAAAAATAAATCAATATACCAGATACTTAACATTGCTCTTGTCAATATTTCAGTCTA
TGGGTATGGCGAGATGGTTGGCTAGTCAGCAAATTGCTATGCAACCAGATTTCTCATTCTATTTTACTGCTGTTGTAACT
TTAGTTACGGGTACTATGTTTTTAATGTGGTTGGGTGAGCAAATTACAGAAAAAGGTGTTGGTAATGGAATTTCCTTAAT
TATCTTTTCTGGAATTGTCTCTAGCATGCCAAATGCTATAGGATCTGTCCTCCAGCAAGTTAAGGAAGGTCAGATGCAAG
CTCTTACACTAGTTATAATTGCAGCAGTAGTAATTGTAGTAACTGGTTTTGTTGTATTTATGGAGCGTGCTCAACGGCGA
ATTCGTGTTAATTATGCACAGAGAACGCAAGGCAGAAAGGTATATGCAGCCCAAACAAGTCATTTACCATTAAAAATAAA
TATGTCAGGTGTGATTCCACCAATATTTGCATCTAGCATTATTTTATTACCAGCAACTTTAGCTCAATTTTTTTCACAAA
CTAAAGGGCTGGGATGGTTATCTGATGTTGGAATGGCACTATCACCAGGTCAACCCTTATATTTGATAGTGTATGCAGCA
GCTATTTTGTTCTTTGCATTCTTTTATGCTGCCTTAGTGTTTAACCCTAAGGATACAGCAGATAACCTGAAAAAATCAGG
AGCATATATTCCTGGAATTCGTCCAGGAGAGCAAACAACTAAATATATCGATTCAGTGATGACTCGTTTGACTTTAGTTG
GAGCCATTTACTTGGTTTTAGTATGTTTGTTGCCACAAATTTTAATGTATACCTGGCATGTTCCATTTTATTTTGGTGGT
ACTTCGTTGCTGATTATAGTTGTTGTTATTATGGATTTTGTAGCACAGGTACAAGCTCATTTAATGACTCAGCAATATGA
TTCTTTATTAAAAAAGGCGAATTTTAGAGGTACTAAGTTACCTGGTCTGCTATGA

Upstream 100 bases:

>100_bases
TTTTATCTGGCGAGCTGACTGCAGCAATTAAACTTAAGGGTTTAAGAGTCACTAAAGGAGCTCGTTCTGCTATTGAGAGT
TTAGGCGGTAGTATAGAAGA

Downstream 100 bases:

>100_bases
TTTATCGGAGTTAGGAATGAAAGTAAGAGCATCAGTAAAGCGAATATGTCGCAATTGTAAAATAATAAAAAGAAGTGGCA
CTATACGAGTAATTTGTAAG

Product: preprotein translocase subunit SecY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 444; Mature: 443

Protein sequence:

>444_residues
MTMKNQKHNGSKPRGGLAELKSRLMFVVLGILVYRLGAHIPVPGLDPAKLANFFSEQQNTIFGLFNMFSGGALSRVTVFA
IGIMPYISASIIIQLFSVVSPKLEQLKKEGESGRRKINQYTRYLTLLLSIFQSMGMARWLASQQIAMQPDFSFYFTAVVT
LVTGTMFLMWLGEQITEKGVGNGISLIIFSGIVSSMPNAIGSVLQQVKEGQMQALTLVIIAAVVIVVTGFVVFMERAQRR
IRVNYAQRTQGRKVYAAQTSHLPLKINMSGVIPPIFASSIILLPATLAQFFSQTKGLGWLSDVGMALSPGQPLYLIVYAA
AILFFAFFYAALVFNPKDTADNLKKSGAYIPGIRPGEQTTKYIDSVMTRLTLVGAIYLVLVCLLPQILMYTWHVPFYFGG
TSLLIIVVVIMDFVAQVQAHLMTQQYDSLLKKANFRGTKLPGLL

Sequences:

>Translated_444_residues
MTMKNQKHNGSKPRGGLAELKSRLMFVVLGILVYRLGAHIPVPGLDPAKLANFFSEQQNTIFGLFNMFSGGALSRVTVFA
IGIMPYISASIIIQLFSVVSPKLEQLKKEGESGRRKINQYTRYLTLLLSIFQSMGMARWLASQQIAMQPDFSFYFTAVVT
LVTGTMFLMWLGEQITEKGVGNGISLIIFSGIVSSMPNAIGSVLQQVKEGQMQALTLVIIAAVVIVVTGFVVFMERAQRR
IRVNYAQRTQGRKVYAAQTSHLPLKINMSGVIPPIFASSIILLPATLAQFFSQTKGLGWLSDVGMALSPGQPLYLIVYAA
AILFFAFFYAALVFNPKDTADNLKKSGAYIPGIRPGEQTTKYIDSVMTRLTLVGAIYLVLVCLLPQILMYTWHVPFYFGG
TSLLIIVVVIMDFVAQVQAHLMTQQYDSLLKKANFRGTKLPGLL
>Mature_443_residues
TMKNQKHNGSKPRGGLAELKSRLMFVVLGILVYRLGAHIPVPGLDPAKLANFFSEQQNTIFGLFNMFSGGALSRVTVFAI
GIMPYISASIIIQLFSVVSPKLEQLKKEGESGRRKINQYTRYLTLLLSIFQSMGMARWLASQQIAMQPDFSFYFTAVVTL
VTGTMFLMWLGEQITEKGVGNGISLIIFSGIVSSMPNAIGSVLQQVKEGQMQALTLVIIAAVVIVVTGFVVFMERAQRRI
RVNYAQRTQGRKVYAAQTSHLPLKINMSGVIPPIFASSIILLPATLAQFFSQTKGLGWLSDVGMALSPGQPLYLIVYAAA
ILFFAFFYAALVFNPKDTADNLKKSGAYIPGIRPGEQTTKYIDSVMTRLTLVGAIYLVLVCLLPQILMYTWHVPFYFGGT
SLLIIVVVIMDFVAQVQAHLMTQQYDSLLKKANFRGTKLPGLL

Specific function: Involved in protein export. Interacts with secA and secE to allow the translocation of proteins across the plasma membrane, by forming part of a channel [H]

COG id: COG0201

COG function: function code U; Preprotein translocase subunit SecY

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secY/SEC61-alpha family [H]

Homologues:

Organism=Escherichia coli, GI1789696, Length=428, Percent_Identity=63.785046728972, Blast_Score=533, Evalue=1e-152,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002208
- InterPro:   IPR023201 [H]

Pfam domain/function: PF00344 SecY [H]

EC number: NA

Molecular weight: Translated: 48982; Mature: 48851

Theoretical pI: Translated: 10.47; Mature: 10.47

Prosite motif: PS00755 SECY_1 ; PS00756 SECY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
TMKNQKHNGSKPRGGLAELKSRLMFVVLGILVYRLGAHIPVPGLDPAKLANFFSEQQNT
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
IFGLFNMFSGGALSRVTVFAIGIMPYISASIIIQLFSVVSPKLEQLKKEGESGRRKINQY
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCHHHHHHHHHH
TRYLTLLLSIFQSMGMARWLASQQIAMQPDFSFYFTAVVTLVTGTMFLMWLGEQITEKGV
HHHHHHHHHHHHHHHHHHHHHHCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GNGISLIIFSGIVSSMPNAIGSVLQQVKEGQMQALTLVIIAAVVIVVTGFVVFMERAQRR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IRVNYAQRTQGRKVYAAQTSHLPLKINMSGVIPPIFASSIILLPATLAQFFSQTKGLGWL
HHHHHHHHCCCCEEEEECCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCH
SDVGMALSPGQPLYLIVYAAAILFFAFFYAALVFNPKDTADNLKKSGAYIPGIRPGEQTT
HHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCHHHH
KYIDSVMTRLTLVGAIYLVLVCLLPQILMYTWHVPFYFGGTSLLIIVVVIMDFVAQVQAH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCHHHHHHHHHHHHHHHHHHHHH
LMTQQYDSLLKKANFRGTKLPGLL
HHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]