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The map label for this gene is surA [H]

Identifier: 54293303

GI number: 54293303

Start: 405226

End: 406515

Strand: Direct

Name: surA [H]

Synonym: lpl0351

Alternate gene names: 54293303

Gene position: 405226-406515 (Clockwise)

Preceding gene: 54293302

Following gene: 54293304

Centisome position: 12.11

GC content: 38.6

Gene sequence:

>1290_bases
ATGTTTAAAAGAATAGCATTGGTATGCGCTTTGTTTTCAGGAGTATGTTTCGCTGAAGGAAAGCAGCTGTTAGATAAAGT
GGTTGCTATAGTAAATGATAATGTCATTACTTCCAGCGAATTGAATGCTCAAGTCGAGTTATCTAAAAAGCAGATTATAG
CTCAAAATATGCAAATGCCAGATGAGTCTGTATTACGTAAGCAAGTATTGCAACATTTAATAGACGTAGATCTGGAAATG
CAAATGGCAAAACAAAATGGTATTACTATTGAAAATGCTGAAATTGATGAAGCGATAGAAAAAATAGCTGCTTCAAATCA
TCTAAATTTATCGCAAATGCGCGATGAAATTACAAAGCAAGGAATTAGCTGGCAAGAATACAGGCAAAATATCCGTAAAG
AAATGCTGATTTCCAGGGTTCAGCAAAAAGCAGTAGGTAAAGATATCATTGTTACTAATGAGCAGGTGGATCAATACTTA
AAAACTGCAGGCCGCATAGAAAATTCTAACTTGACGTATCATTTAAAAAATATTGTTATCCCTTTAAGCGAAGAACCAAC
GACCAGACAGCTTCAAAGAGCTAAAATCGAAGCAGAAAACTTGTTAAATAAAATTAAAAAAGGTGAAGACTTTAGCCGTT
TGGCAATAGAAGAATCAAGTGGAGAGTTTGCACTGGAAGGTGGTGATTTGGGTGAGCGTCATTTGGCTGAGTTGCCTGAG
GTATTTGCCAAGGAAGTAGTACATATGAAAGTAGGTCAGGTGGCCGGCCCGATAAGAGCAGGAAATGGATTTCATTTGAT
CAAATTAGTAGCTGTTGGCGGCGAGAATCAGCGTCATGTGATCACTCAAACCCATGTCAGACATATACTGCTTAAACCCG
ATGCCAGCATGGTGCCTTCTGAAGCAATTAAGCAAGTCAATAACATTTACCGGCAAATACAGTCAGGCAAAGATTTTGCT
CTTATGGCTAAACAATATTCACTCGATGCTGCCAGTGCAGTGAAAGGCGGTGATTTAGGATGGGTTAATCCTGGTGAATT
AGTTCCAGAGTTTGAAAAAACCATGAACAGTTTGCCATTACATAAAGTCAGTAAACCGGTAAAAACCCAGTACGGATGGC
ATCTCATTGAAGTGATTGCACGCAGACAGAAGGATGATTCAGAAGCTTTTAAGAAGCAACAGGTCAGGCAATTTCTACAA
CAGCGCAAGTTTGTAGAGGCAGTGCAAAACTGGCAACAACATTTGCGCTCTCAAGCTTATATTAATATAGTTGATAAGGA
TTTAGCATGA

Upstream 100 bases:

>100_bases
ATCTGTTTTTTATAAATTATGGTGCAAATTAAGCAAACTTGCTTGTATTTTGACAAAGAATAACATAAATTGCCCGAAAA
ATGTGAATGAGGATTATGGC

Downstream 100 bases:

>100_bases
ACCCACTGCTTATTAGTAGTGGAGAGCCTGCTGGAATTGGCCCGGACTTATGCCTGGCTTTGGCAGAAACCGATTTGCCC
GTAGTGATATTGGGTGATCT

Product: hypothetical protein

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase surA; PPIase surA; Rotamase surA [H]

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MFKRIALVCALFSGVCFAEGKQLLDKVVAIVNDNVITSSELNAQVELSKKQIIAQNMQMPDESVLRKQVLQHLIDVDLEM
QMAKQNGITIENAEIDEAIEKIAASNHLNLSQMRDEITKQGISWQEYRQNIRKEMLISRVQQKAVGKDIIVTNEQVDQYL
KTAGRIENSNLTYHLKNIVIPLSEEPTTRQLQRAKIEAENLLNKIKKGEDFSRLAIEESSGEFALEGGDLGERHLAELPE
VFAKEVVHMKVGQVAGPIRAGNGFHLIKLVAVGGENQRHVITQTHVRHILLKPDASMVPSEAIKQVNNIYRQIQSGKDFA
LMAKQYSLDAASAVKGGDLGWVNPGELVPEFEKTMNSLPLHKVSKPVKTQYGWHLIEVIARRQKDDSEAFKKQQVRQFLQ
QRKFVEAVQNWQQHLRSQAYINIVDKDLA

Sequences:

>Translated_429_residues
MFKRIALVCALFSGVCFAEGKQLLDKVVAIVNDNVITSSELNAQVELSKKQIIAQNMQMPDESVLRKQVLQHLIDVDLEM
QMAKQNGITIENAEIDEAIEKIAASNHLNLSQMRDEITKQGISWQEYRQNIRKEMLISRVQQKAVGKDIIVTNEQVDQYL
KTAGRIENSNLTYHLKNIVIPLSEEPTTRQLQRAKIEAENLLNKIKKGEDFSRLAIEESSGEFALEGGDLGERHLAELPE
VFAKEVVHMKVGQVAGPIRAGNGFHLIKLVAVGGENQRHVITQTHVRHILLKPDASMVPSEAIKQVNNIYRQIQSGKDFA
LMAKQYSLDAASAVKGGDLGWVNPGELVPEFEKTMNSLPLHKVSKPVKTQYGWHLIEVIARRQKDDSEAFKKQQVRQFLQ
QRKFVEAVQNWQQHLRSQAYINIVDKDLA
>Mature_429_residues
MFKRIALVCALFSGVCFAEGKQLLDKVVAIVNDNVITSSELNAQVELSKKQIIAQNMQMPDESVLRKQVLQHLIDVDLEM
QMAKQNGITIENAEIDEAIEKIAASNHLNLSQMRDEITKQGISWQEYRQNIRKEMLISRVQQKAVGKDIIVTNEQVDQYL
KTAGRIENSNLTYHLKNIVIPLSEEPTTRQLQRAKIEAENLLNKIKKGEDFSRLAIEESSGEFALEGGDLGERHLAELPE
VFAKEVVHMKVGQVAGPIRAGNGFHLIKLVAVGGENQRHVITQTHVRHILLKPDASMVPSEAIKQVNNIYRQIQSGKDFA
LMAKQYSLDAASAVKGGDLGWVNPGELVPEFEKTMNSLPLHKVSKPVKTQYGWHLIEVIARRQKDDSEAFKKQQVRQFLQ
QRKFVEAVQNWQQHLRSQAYINIVDKDLA

Specific function: Chaperone involved in the correct folding and assembly of outer membrane proteins. It recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Periplasm. Note=Is capable of associating with the outer membrane (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PpiC domains [H]

Homologues:

Organism=Escherichia coli, GI1786238, Length=424, Percent_Identity=35.6132075471698, Blast_Score=279, Evalue=3e-76,
Organism=Escherichia coli, GI1790211, Length=94, Percent_Identity=36.1702127659575, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023034
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 48490; Mature: 48490

Theoretical pI: Translated: 8.24; Mature: 8.24

Prosite motif: PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKRIALVCALFSGVCFAEGKQLLDKVVAIVNDNVITSSELNAQVELSKKQIIAQNMQMP
CHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHHHHCCCC
DESVLRKQVLQHLIDVDLEMQMAKQNGITIENAEIDEAIEKIAASNHLNLSQMRDEITKQ
HHHHHHHHHHHHHHCCCHHHHHHHHCCCEEECCHHHHHHHHHHHCCCCCHHHHHHHHHHC
GISWQEYRQNIRKEMLISRVQQKAVGKDIIVTNEQVDQYLKTAGRIENSNLTYHLKNIVI
CCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHCCCCCCCCEEEEEEEEE
PLSEEPTTRQLQRAKIEAENLLNKIKKGEDFSRLAIEESSGEFALEGGDLGERHLAELPE
ECCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHEEECCCCCEEECCCCCCHHHHHHHHH
VFAKEVVHMKVGQVAGPIRAGNGFHLIKLVAVGGENQRHVITQTHVRHILLKPDASMVPS
HHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEECCCCCCEEHHHHHHHHEEECCCCCCCCH
EAIKQVNNIYRQIQSGKDFALMAKQYSLDAASAVKGGDLGWVNPGELVPEFEKTMNSLPL
HHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHCCCCCCCCCCCHHHCHHHHHHHHCCCH
HKVSKPVKTQYGWHLIEVIARRQKDDSEAFKKQQVRQFLQQRKFVEAVQNWQQHLRSQAY
HHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
INIVDKDLA
EEHHCCCCC
>Mature Secondary Structure
MFKRIALVCALFSGVCFAEGKQLLDKVVAIVNDNVITSSELNAQVELSKKQIIAQNMQMP
CHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHHHHCCCC
DESVLRKQVLQHLIDVDLEMQMAKQNGITIENAEIDEAIEKIAASNHLNLSQMRDEITKQ
HHHHHHHHHHHHHHCCCHHHHHHHHCCCEEECCHHHHHHHHHHHCCCCCHHHHHHHHHHC
GISWQEYRQNIRKEMLISRVQQKAVGKDIIVTNEQVDQYLKTAGRIENSNLTYHLKNIVI
CCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHCCCCCCCCEEEEEEEEE
PLSEEPTTRQLQRAKIEAENLLNKIKKGEDFSRLAIEESSGEFALEGGDLGERHLAELPE
ECCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHEEECCCCCEEECCCCCCHHHHHHHHH
VFAKEVVHMKVGQVAGPIRAGNGFHLIKLVAVGGENQRHVITQTHVRHILLKPDASMVPS
HHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEECCCCCCEEHHHHHHHHEEECCCCCCCCH
EAIKQVNNIYRQIQSGKDFALMAKQYSLDAASAVKGGDLGWVNPGELVPEFEKTMNSLPL
HHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHCCCCCCCCCCCHHHCHHHHHHHHCCCH
HKVSKPVKTQYGWHLIEVIARRQKDDSEAFKKQQVRQFLQQRKFVEAVQNWQQHLRSQAY
HHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
INIVDKDLA
EEHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA