Click here to switch to the map view.

The map label for this gene is lptD [H]

Identifier: 54293302

GI number: 54293302

Start: 402531

End: 405050

Strand: Direct

Name: lptD [H]

Synonym: lpl0350

Alternate gene names: 54293302

Gene position: 402531-405050 (Clockwise)

Preceding gene: 54293299

Following gene: 54293303

Centisome position: 12.03

GC content: 39.76

Gene sequence:

>2520_bases
ATGGCCATAGGGATAACTGCTTGTGTTTTATCTTTGATAAATTATCAAGGCTTAGCCTATTCTGCTGCCTTGATAAATGA
ACCTATTCAAGCTTGCGTGATTGCGCGAGAAGTCGATTTAACAGACGATATAAGAACTAAATTTGCCCAATGTTTGGGTT
GGCAAGCTGATCAAAGTTCCCCTGTGTGCCTCGGTTTTTATAAACCCATTACGGTGACACCGTTAGCTAGTCCAGATGAA
GTACGTATTCTGGCAGATACGGCTTCCTTCTATCGAACTCAAAGATCCACTTTATCCGGGCATGTAGAAATGCAGCAGGG
CCAAAGAGTAGTTAACGCTCAAACAGCCTATGTGTACAGGGATCCTAAAACGAATGAAGTAACAAAAATTGAATTTTTGA
ATCATGTACGTTATTTAGAACCTGATAGAATGATGATCGCTAGAAAAGCAGTTGTGTATCCTCAAGATAAATCGGGTGAA
GTGGAAGATGTTCTTTATCGATTTAATACCAATAGAAGCAATGCATTGCTGCCTGCCTGGGGTAGGGCAAGTTTAATCAA
GCGTTTTGCAAATCAGGACTACTTTTTGAAAGAGGCAACTTACACGACTTGCGCGCCTCAAGATAAGGCTTGGGCTATCG
AGGCCGAATCCATCAGTATAAACAACGAAAAAGGAAAGGGCATTGCTCGCAATGCCAAATTACGTATCCACGAATGGCCT
GTGCTTTATACCCCTTATTTGAGTTTTCCTACCAATAGAGATAGAAAATCGGGGTTTCTGATGCCCATAGTGGGTTATTC
CAATGTAGGGGGAGCTGATTTGGGCATCCCTTATTATTGGAATATGGCGCCAAATTATGACATGACTCTCGTTCCTCACA
TTTATACAAAACGCGGCTTGATGTTGGGAGGACAATTTAGATATTTGACTTCAAAGAGCACTGGAACATTTAATGGAAAT
TTTTTACCAAAAGATAAAGCCTTTGGCAGGTTTTTACAGGACAATGAGGTAGAGTTCCCTCAGATTCGAGGACTTTCCAC
GAATCGTTGGGAAGTAAATTTTGTCGATTCAACCCAATTTCTCTCTGATCTTCAATTAAATGTTAATTTTCAACAGGTTT
CTGATGATTATTACTTGCAAGATTTCAGTACAAATTTGGCATCGGTAACTCAAAGACAATTATTGCGCCAGGCTGATTTA
ACCTACACTACCGAAAACTGGACTTTTAGAGGTATGGGACAAAGTTATCAAACGTTACATCCAATTAACGAAATCCCGGT
TTCCCCTGTTTATGAACGGTTACCGCAACTTATGGCACGAGGTTATTATGATGATTTACCTTTTAATGCCCAATTGAATA
TCCTTGGTCAATACGACCAGTTTCACTGGCCTAATGACTCCTGGAATATAGCTCTTAATAATATGCCTCAGGGGCCCCGG
TTTCATCTGAATCCCATTTTATCAGTGCCAATGATGAAGCCTTGGGGATATGTTACTCCCTCAGTACAATTTGTGGAAAA
TTATTACGATATTTCAAGGAATTATACTTGGGGCACATCTCGAGCTAACTATAACCTGACAATACCTCGCTATAGCCTTG
ATGGCGGATTGTATTTCGAACGAGATTTGCATCTTAAGGGTACGTATTACATACAAACTTTAGAGCCCAGGTTATTCTAT
TTAAGAGTACCTTATTATAACCAAACACTTATTCCAGTTTATGATTCAGGGTTTATGATTTTTAACGTCGATCAATTGTT
TAGAACCAATCGCTTTTCAGGGTTTGATAGAATCGGAGATGCCAATCAGCTAAGTTATGCCCTTACCACAAGGTGGTTAG
AAGATGAATCAGGTGCTGAGAAAGCGAATTTTTCTATTGGCCAAATCAAATATTTCAGTGAGAGAAGAGTACAACTTTGT
CAAAGCCCTACCGGGTTTTGTACCGATAATCCAGATACCTTTGGCAACTTATCGTCTACTTTTGGAACATCGCCTGTTGC
GTCAAGGGCGGTATATAAATTTAATCCAGCTTGGGGAATAACAGGGGATTACATTTGGGATCCGGCAACAAGGGCTACAA
ATAATGCGGATTTGAATTTGCACTATCAGCCAGCTCGTAATGCTATCATCAATGGCGGGTATAGTTATTTGGTTAATGGT
GACGTTACTCAAGTAAGAAATAATGACACTGAAAATAATGCCTTACATCAAGCCATTTTATCCGCTGCCTGGCCGCTTAG
TGAAAAATGGAGTGGTATCGGAGCCTATAGTTATAATATCAGTAAAAATTACAGTATGATGTCATTTCTTGGCGTTCAAT
ATGATAGTTGTTGCTGGGCTATGCGTATTTTGGGAGGGCGAACTTTTAGAAGTTTAAATGAAGAATTTGAGCCTCGGTAC
AATAACAACATTTATTTGCAAATATTACTAAAAGGCTTAGGATCAGTAGCTAGCAGTGATCCAAGTGGTATATTGAATAC
CTATATCCCAGGATACTATGACCCTTTCCGACGACGTTAA

Upstream 100 bases:

>100_bases
TATTTCATTTATCGCCTTATTGCGAGGTTTACTCTATTGCCATTTAAAAAGACCATTTAAAAAATGGCCTGAATCTTTAT
TTTCAGTGAAATGGGTTTTA

Downstream 100 bases:

>100_bases
AATCCAAAGATAAATGACGCAATAAAAGCGAGTCAGGTTTAGGTGTTTAGGTTAGTACAGGTTGAAAATATTTTAATCTG
TTTTTTATAAATTATGGTGC

Product: hypothetical protein

Products: NA

Alternate protein names: Organic solvent tolerance protein [H]

Number of amino acids: Translated: 839; Mature: 838

Protein sequence:

>839_residues
MAIGITACVLSLINYQGLAYSAALINEPIQACVIAREVDLTDDIRTKFAQCLGWQADQSSPVCLGFYKPITVTPLASPDE
VRILADTASFYRTQRSTLSGHVEMQQGQRVVNAQTAYVYRDPKTNEVTKIEFLNHVRYLEPDRMMIARKAVVYPQDKSGE
VEDVLYRFNTNRSNALLPAWGRASLIKRFANQDYFLKEATYTTCAPQDKAWAIEAESISINNEKGKGIARNAKLRIHEWP
VLYTPYLSFPTNRDRKSGFLMPIVGYSNVGGADLGIPYYWNMAPNYDMTLVPHIYTKRGLMLGGQFRYLTSKSTGTFNGN
FLPKDKAFGRFLQDNEVEFPQIRGLSTNRWEVNFVDSTQFLSDLQLNVNFQQVSDDYYLQDFSTNLASVTQRQLLRQADL
TYTTENWTFRGMGQSYQTLHPINEIPVSPVYERLPQLMARGYYDDLPFNAQLNILGQYDQFHWPNDSWNIALNNMPQGPR
FHLNPILSVPMMKPWGYVTPSVQFVENYYDISRNYTWGTSRANYNLTIPRYSLDGGLYFERDLHLKGTYYIQTLEPRLFY
LRVPYYNQTLIPVYDSGFMIFNVDQLFRTNRFSGFDRIGDANQLSYALTTRWLEDESGAEKANFSIGQIKYFSERRVQLC
QSPTGFCTDNPDTFGNLSSTFGTSPVASRAVYKFNPAWGITGDYIWDPATRATNNADLNLHYQPARNAIINGGYSYLVNG
DVTQVRNNDTENNALHQAILSAAWPLSEKWSGIGAYSYNISKNYSMMSFLGVQYDSCCWAMRILGGRTFRSLNEEFEPRY
NNNIYLQILLKGLGSVASSDPSGILNTYIPGYYDPFRRR

Sequences:

>Translated_839_residues
MAIGITACVLSLINYQGLAYSAALINEPIQACVIAREVDLTDDIRTKFAQCLGWQADQSSPVCLGFYKPITVTPLASPDE
VRILADTASFYRTQRSTLSGHVEMQQGQRVVNAQTAYVYRDPKTNEVTKIEFLNHVRYLEPDRMMIARKAVVYPQDKSGE
VEDVLYRFNTNRSNALLPAWGRASLIKRFANQDYFLKEATYTTCAPQDKAWAIEAESISINNEKGKGIARNAKLRIHEWP
VLYTPYLSFPTNRDRKSGFLMPIVGYSNVGGADLGIPYYWNMAPNYDMTLVPHIYTKRGLMLGGQFRYLTSKSTGTFNGN
FLPKDKAFGRFLQDNEVEFPQIRGLSTNRWEVNFVDSTQFLSDLQLNVNFQQVSDDYYLQDFSTNLASVTQRQLLRQADL
TYTTENWTFRGMGQSYQTLHPINEIPVSPVYERLPQLMARGYYDDLPFNAQLNILGQYDQFHWPNDSWNIALNNMPQGPR
FHLNPILSVPMMKPWGYVTPSVQFVENYYDISRNYTWGTSRANYNLTIPRYSLDGGLYFERDLHLKGTYYIQTLEPRLFY
LRVPYYNQTLIPVYDSGFMIFNVDQLFRTNRFSGFDRIGDANQLSYALTTRWLEDESGAEKANFSIGQIKYFSERRVQLC
QSPTGFCTDNPDTFGNLSSTFGTSPVASRAVYKFNPAWGITGDYIWDPATRATNNADLNLHYQPARNAIINGGYSYLVNG
DVTQVRNNDTENNALHQAILSAAWPLSEKWSGIGAYSYNISKNYSMMSFLGVQYDSCCWAMRILGGRTFRSLNEEFEPRY
NNNIYLQILLKGLGSVASSDPSGILNTYIPGYYDPFRRR
>Mature_838_residues
AIGITACVLSLINYQGLAYSAALINEPIQACVIAREVDLTDDIRTKFAQCLGWQADQSSPVCLGFYKPITVTPLASPDEV
RILADTASFYRTQRSTLSGHVEMQQGQRVVNAQTAYVYRDPKTNEVTKIEFLNHVRYLEPDRMMIARKAVVYPQDKSGEV
EDVLYRFNTNRSNALLPAWGRASLIKRFANQDYFLKEATYTTCAPQDKAWAIEAESISINNEKGKGIARNAKLRIHEWPV
LYTPYLSFPTNRDRKSGFLMPIVGYSNVGGADLGIPYYWNMAPNYDMTLVPHIYTKRGLMLGGQFRYLTSKSTGTFNGNF
LPKDKAFGRFLQDNEVEFPQIRGLSTNRWEVNFVDSTQFLSDLQLNVNFQQVSDDYYLQDFSTNLASVTQRQLLRQADLT
YTTENWTFRGMGQSYQTLHPINEIPVSPVYERLPQLMARGYYDDLPFNAQLNILGQYDQFHWPNDSWNIALNNMPQGPRF
HLNPILSVPMMKPWGYVTPSVQFVENYYDISRNYTWGTSRANYNLTIPRYSLDGGLYFERDLHLKGTYYIQTLEPRLFYL
RVPYYNQTLIPVYDSGFMIFNVDQLFRTNRFSGFDRIGDANQLSYALTTRWLEDESGAEKANFSIGQIKYFSERRVQLCQ
SPTGFCTDNPDTFGNLSSTFGTSPVASRAVYKFNPAWGITGDYIWDPATRATNNADLNLHYQPARNAIINGGYSYLVNGD
VTQVRNNDTENNALHQAILSAAWPLSEKWSGIGAYSYNISKNYSMMSFLGVQYDSCCWAMRILGGRTFRSLNEEFEPRYN
NNIYLQILLKGLGSVASSDPSGILNTYIPGYYDPFRRR

Specific function: Involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis [H]

COG id: COG1452

COG function: function code M; Organic solvent tolerance protein OstA

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lptD family [H]

Homologues:

Organism=Escherichia coli, GI1786239, Length=794, Percent_Identity=28.463476070529, Blast_Score=298, Evalue=1e-81,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020889
- InterPro:   IPR005653
- InterPro:   IPR007543 [H]

Pfam domain/function: PF03968 OstA; PF04453 OstA_C [H]

EC number: NA

Molecular weight: Translated: 95970; Mature: 95839

Theoretical pI: Translated: 7.47; Mature: 7.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIGITACVLSLINYQGLAYSAALINEPIQACVIAREVDLTDDIRTKFAQCLGWQADQSS
CCCCHHHHHHHHHCCCCCEEEHHHHHCCHHHHEEEEECCCCHHHHHHHHHHHCCCCCCCC
PVCLGFYKPITVTPLASPDEVRILADTASFYRTQRSTLSGHVEMQQGQRVVNAQTAYVYR
CEEEEEECCEEEECCCCCCCEEEEEECHHHHHHHHHHHCCEEEHHCCCEEEECEEEEEEE
DPKTNEVTKIEFLNHVRYLEPDRMMIARKAVVYPQDKSGEVEDVLYRFNTNRSNALLPAW
CCCCCCEEHHHHHHHHHCCCCCHHEEEEHEEECCCCCCCCHHHHHEEECCCCCCEEECCC
GRASLIKRFANQDYFLKEATYTTCAPQDKAWAIEAESISINNEKGKGIARNAKLRIHEWP
CHHHHHHHHCCCCEEEECCCEEECCCCCCEEEEEEEEEEECCCCCCCEECCCEEEEEECC
VLYTPYLSFPTNRDRKSGFLMPIVGYSNVGGADLGIPYYWNMAPNYDMTLVPHIYTKRGL
EEEECCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCEEECCCCCCCEEEECHHHCCCCE
MLGGQFRYLTSKSTGTFNGNFLPKDKAFGRFLQDNEVEFPQIRGLSTNRWEVNFVDSTQF
EECCEEEEEECCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCHHH
LSDLQLNVNFQQVSDDYYLQDFSTNLASVTQRQLLRQADLTYTTENWTFRGMGQSYQTLH
HHHEEEEEEHEECCCCEEEHHHHHHHHHHHHHHHHHHCCCEEEECCCEEEECCCCCHHHC
PINEIPVSPVYERLPQLMARGYYDDLPFNAQLNILGQYDQFHWPNDSWNIALNNMPQGPR
CHHCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCCCEEEECCCCCCCC
FHLNPILSVPMMKPWGYVTPSVQFVENYYDISRNYTWGTSRANYNLTIPRYSLDGGLYFE
EECCCEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEECEEECCCCEEEE
RDLHLKGTYYIQTLEPRLFYLRVPYYNQTLIPVYDSGFMIFNVDQLFRTNRFSGFDRIGD
EEEEECEEEEEEEECCEEEEEECCCCCCEEEEEECCCEEEEEHHHHHHCCCCCCCHHCCC
ANQLSYALTTRWLEDESGAEKANFSIGQIKYFSERRVQLCQSPTGFCTDNPDTFGNLSST
CCCEEEEEHEEEECCCCCCCCCCCCEEEEEEHHHHHHHHHCCCCCCCCCCCCCCCCCHHH
FGTSPVASRAVYKFNPAWGITGDYIWDPATRATNNADLNLHYQPARNAIINGGYSYLVNG
CCCCCHHCCEEEEECCCCCCCCCEEECCCCCCCCCCEEEEEECCCCCEEEECCEEEEECC
DVTQVRNNDTENNALHQAILSAAWPLSEKWSGIGAYSYNISKNYSMMSFLGVQYDSCCWA
CEEEECCCCCCHHHHHHHHHHHCCCCCHHCCCCEEEEEECCCCCCCHHHHCCCHHHHHHH
MRILGGRTFRSLNEEFEPRYNNNIYLQILLKGLGSVASSDPSGILNTYIPGYYDPFRRR
HHHHCCHHHHHHHHHCCCCCCCCEEEEEEEHHHHHHCCCCCCCHHHHCCCCCCCHHHCC
>Mature Secondary Structure 
AIGITACVLSLINYQGLAYSAALINEPIQACVIAREVDLTDDIRTKFAQCLGWQADQSS
CCCHHHHHHHHHCCCCCEEEHHHHHCCHHHHEEEEECCCCHHHHHHHHHHHCCCCCCCC
PVCLGFYKPITVTPLASPDEVRILADTASFYRTQRSTLSGHVEMQQGQRVVNAQTAYVYR
CEEEEEECCEEEECCCCCCCEEEEEECHHHHHHHHHHHCCEEEHHCCCEEEECEEEEEEE
DPKTNEVTKIEFLNHVRYLEPDRMMIARKAVVYPQDKSGEVEDVLYRFNTNRSNALLPAW
CCCCCCEEHHHHHHHHHCCCCCHHEEEEHEEECCCCCCCCHHHHHEEECCCCCCEEECCC
GRASLIKRFANQDYFLKEATYTTCAPQDKAWAIEAESISINNEKGKGIARNAKLRIHEWP
CHHHHHHHHCCCCEEEECCCEEECCCCCCEEEEEEEEEEECCCCCCCEECCCEEEEEECC
VLYTPYLSFPTNRDRKSGFLMPIVGYSNVGGADLGIPYYWNMAPNYDMTLVPHIYTKRGL
EEEECCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCEEECCCCCCCEEEECHHHCCCCE
MLGGQFRYLTSKSTGTFNGNFLPKDKAFGRFLQDNEVEFPQIRGLSTNRWEVNFVDSTQF
EECCEEEEEECCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCHHH
LSDLQLNVNFQQVSDDYYLQDFSTNLASVTQRQLLRQADLTYTTENWTFRGMGQSYQTLH
HHHEEEEEEHEECCCCEEEHHHHHHHHHHHHHHHHHHCCCEEEECCCEEEECCCCCHHHC
PINEIPVSPVYERLPQLMARGYYDDLPFNAQLNILGQYDQFHWPNDSWNIALNNMPQGPR
CHHCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCCCEEEECCCCCCCC
FHLNPILSVPMMKPWGYVTPSVQFVENYYDISRNYTWGTSRANYNLTIPRYSLDGGLYFE
EECCCEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEECEEECCCCEEEE
RDLHLKGTYYIQTLEPRLFYLRVPYYNQTLIPVYDSGFMIFNVDQLFRTNRFSGFDRIGD
EEEEECEEEEEEEECCEEEEEECCCCCCEEEEEECCCEEEEEHHHHHHCCCCCCCHHCCC
ANQLSYALTTRWLEDESGAEKANFSIGQIKYFSERRVQLCQSPTGFCTDNPDTFGNLSST
CCCEEEEEHEEEECCCCCCCCCCCCEEEEEEHHHHHHHHHCCCCCCCCCCCCCCCCCHHH
FGTSPVASRAVYKFNPAWGITGDYIWDPATRATNNADLNLHYQPARNAIINGGYSYLVNG
CCCCCHHCCEEEEECCCCCCCCCEEECCCCCCCCCCEEEEEECCCCCEEEECCEEEEECC
DVTQVRNNDTENNALHQAILSAAWPLSEKWSGIGAYSYNISKNYSMMSFLGVQYDSCCWA
CEEEECCCCCCHHHHHHHHHHHCCCCCHHCCCCEEEEEECCCCCCCHHHHCCCHHHHHHH
MRILGGRTFRSLNEEFEPRYNNNIYLQILLKGLGSVASSDPSGILNTYIPGYYDPFRRR
HHHHCCHHHHHHHHHCCCCCCCCEEEEEEEHHHHHHCCCCCCCHHHHCCCCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA