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The map label for this gene is yfdE [H]

Identifier: 54293200

GI number: 54293200

Start: 274921

End: 275982

Strand: Direct

Name: yfdE [H]

Synonym: lpl0248

Alternate gene names: 54293200

Gene position: 274921-275982 (Clockwise)

Preceding gene: 54293199

Following gene: 54293205

Centisome position: 8.22

GC content: 43.79

Gene sequence:

>1062_bases
ATGTTAAAGGGCTTAAAGGTCATTGATCTGAGTACGGTTCTTGCAGGCCCCTCTGTAGGCACTTTTTTTGCCGAGTTAGG
TGCTTCAGTTGTTAAAATTGAGCATCCTGTGCATAAGGATGTGACAAGAACATGGAAACTCCCTGGAGAGGATCCTCATT
CTGAGATTTCAGCTTATTTTGCCAGTGTTAATTTTGGAAAGGACTATTTGTTTTTAGATCTCATGAAGGAAGAGGATTAT
CTCTGTTTCCTTAACCTTATTGCAGAAGCAGATATTTTAATTATGAATTTTAAAAAGGGAGATGACATAAAGCTGCGTGT
ACAAGATGATCATCTACACAGTATTAATCCGCGCCTTATCATTGGAAAAATCAATGGCTACGGTGAAGAAAGCGATCGCG
TTGCCTATGATCTTGTTCTTCAGGGTGAAAGCGGTTTTATGTCAATCAATGGGACACAGGACAGCGGCCCGGTAAAAATG
CCAGTCGCCCTAATTGATGTCCTTGCAGCCCATCACCTGAAAGAAGCCATCCTTCTGGCTCTCTATCATCGGGAAAAAAA
CGGGAAAGGCAGGGTTGTCTCTGTTTCACTTTATGATGCGGCTGTTAGCAGTCTTGTCAATCAGGCATCGAATTACCTGA
TGACTGGGCAGGTGCCGCAGCGCATCGGATCACTGCATCCCAATATTGCCCCCTATGGCGAATTGTTCCAGACATCTGAT
GGGGCGCTTATCGTTCTTGCAATAGGGTCGGATCGGCATTTTGTAAAACTATGCAATATCCTTGGGCTAAAGGATTTACC
AGGAAAAGACGAATTCCGACACAATCAAAACAGGGTGAGGAATCGGGAGCAACTCGCTGCACTAATTGCTGAACAAACAG
AGAAACTCCAGAGCAGTGAGCTTCTCGAAATGTTGCACAGGGAAAATATTCCTGCTGGCAAAATTATGGATCTCAAGGAC
GTTTTCGATAATGAGCGTGCGAAATCCCTCATTCGCAAGGAAGTCATTGATGATGTTCACACAGCGCGCGTTACATCCGT
TGTTTTTAAACAGACTTTATAA

Upstream 100 bases:

>100_bases
GGATATTGATTTGAGGTCCCTTTGGTCAGTTCTGCATAATTTCCCAATGTGCAAACTCGTAAAAACAACGAATGTCTATT
GAGATTTGGAAAACAGGTAT

Downstream 100 bases:

>100_bases
CCAAAGGGGAGCCATTGAATTATGCAGATGAAGAATATTAGTCCTCATGCATAAGCTGTCTCTTCATTGTTGCGCTGCAA
ACGTTTCTGCTGATTTCATT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MLKGLKVIDLSTVLAGPSVGTFFAELGASVVKIEHPVHKDVTRTWKLPGEDPHSEISAYFASVNFGKDYLFLDLMKEEDY
LCFLNLIAEADILIMNFKKGDDIKLRVQDDHLHSINPRLIIGKINGYGEESDRVAYDLVLQGESGFMSINGTQDSGPVKM
PVALIDVLAAHHLKEAILLALYHREKNGKGRVVSVSLYDAAVSSLVNQASNYLMTGQVPQRIGSLHPNIAPYGELFQTSD
GALIVLAIGSDRHFVKLCNILGLKDLPGKDEFRHNQNRVRNREQLAALIAEQTEKLQSSELLEMLHRENIPAGKIMDLKD
VFDNERAKSLIRKEVIDDVHTARVTSVVFKQTL

Sequences:

>Translated_353_residues
MLKGLKVIDLSTVLAGPSVGTFFAELGASVVKIEHPVHKDVTRTWKLPGEDPHSEISAYFASVNFGKDYLFLDLMKEEDY
LCFLNLIAEADILIMNFKKGDDIKLRVQDDHLHSINPRLIIGKINGYGEESDRVAYDLVLQGESGFMSINGTQDSGPVKM
PVALIDVLAAHHLKEAILLALYHREKNGKGRVVSVSLYDAAVSSLVNQASNYLMTGQVPQRIGSLHPNIAPYGELFQTSD
GALIVLAIGSDRHFVKLCNILGLKDLPGKDEFRHNQNRVRNREQLAALIAEQTEKLQSSELLEMLHRENIPAGKIMDLKD
VFDNERAKSLIRKEVIDDVHTARVTSVVFKQTL
>Mature_353_residues
MLKGLKVIDLSTVLAGPSVGTFFAELGASVVKIEHPVHKDVTRTWKLPGEDPHSEISAYFASVNFGKDYLFLDLMKEEDY
LCFLNLIAEADILIMNFKKGDDIKLRVQDDHLHSINPRLIIGKINGYGEESDRVAYDLVLQGESGFMSINGTQDSGPVKM
PVALIDVLAAHHLKEAILLALYHREKNGKGRVVSVSLYDAAVSSLVNQASNYLMTGQVPQRIGSLHPNIAPYGELFQTSD
GALIVLAIGSDRHFVKLCNILGLKDLPGKDEFRHNQNRVRNREQLAALIAEQTEKLQSSELLEMLHRENIPAGKIMDLKD
VFDNERAKSLIRKEVIDDVHTARVTSVVFKQTL

Specific function: Unknown

COG id: COG1804

COG function: function code C; Predicted acyl-CoA transferases/carnitine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CaiB/BaiF CoA-transferase family [H]

Homologues:

Organism=Homo sapiens, GI300863128, Length=326, Percent_Identity=32.5153374233129, Blast_Score=177, Evalue=9e-45,
Organism=Homo sapiens, GI300863124, Length=326, Percent_Identity=32.5153374233129, Blast_Score=177, Evalue=1e-44,
Organism=Homo sapiens, GI13376042, Length=326, Percent_Identity=31.2883435582822, Blast_Score=153, Evalue=3e-37,
Organism=Homo sapiens, GI300863126, Length=326, Percent_Identity=28.5276073619632, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI266456254, Length=303, Percent_Identity=26.4026402640264, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI42794625, Length=303, Percent_Identity=26.4026402640264, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI266458393, Length=274, Percent_Identity=28.1021897810219, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI266458397, Length=257, Percent_Identity=27.6264591439689, Blast_Score=80, Evalue=3e-15,
Organism=Escherichia coli, GI87082093, Length=324, Percent_Identity=35.8024691358025, Blast_Score=189, Evalue=3e-49,
Organism=Escherichia coli, GI1788717, Length=351, Percent_Identity=29.0598290598291, Blast_Score=111, Evalue=7e-26,
Organism=Escherichia coli, GI1786222, Length=365, Percent_Identity=24.3835616438356, Blast_Score=79, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24648431, Length=333, Percent_Identity=32.4324324324324, Blast_Score=173, Evalue=2e-43,
Organism=Drosophila melanogaster, GI24585488, Length=354, Percent_Identity=24.8587570621469, Blast_Score=84, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003673 [H]

Pfam domain/function: PF02515 CoA_transf_3 [H]

EC number: NA

Molecular weight: Translated: 39278; Mature: 39278

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKGLKVIDLSTVLAGPSVGTFFAELGASVVKIEHPVHKDVTRTWKLPGEDPHSEISAYF
CCCCCEEEEHHHHHCCCCHHHHHHHHCCEEEEECCCHHHHHHHEECCCCCCCHHHHHHHH
ASVNFGKDYLFLDLMKEEDYLCFLNLIAEADILIMNFKKGDDIKLRVQDDHLHSINPRLI
HEECCCCCEEEEEEECCCCCEEEHHHHHCCCEEEEEECCCCCEEEEEECCCCCCCCCEEE
IGKINGYGEESDRVAYDLVLQGESGFMSINGTQDSGPVKMPVALIDVLAAHHLKEAILLA
EECCCCCCCCCCCEEEEEEEECCCCEEEECCCCCCCCEEHHHHHHHHHHHHHHHHHHHHH
LYHREKNGKGRVVSVSLYDAAVSSLVNQASNYLMTGQVPQRIGSLHPNIAPYGELFQTSD
HHHHCCCCCCCEEEEEHHHHHHHHHHHHHHCEEEECCHHHHHHCCCCCCCCCHHHHCCCC
GALIVLAIGSDRHFVKLCNILGLKDLPGKDEFRHNQNRVRNREQLAALIAEQTEKLQSSE
CCEEEEEECCCCHHHHHHHHHCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
LLEMLHRENIPAGKIMDLKDVFDNERAKSLIRKEVIDDVHTARVTSVVFKQTL
HHHHHHHCCCCCCCEEEHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLKGLKVIDLSTVLAGPSVGTFFAELGASVVKIEHPVHKDVTRTWKLPGEDPHSEISAYF
CCCCCEEEEHHHHHCCCCHHHHHHHHCCEEEEECCCHHHHHHHEECCCCCCCHHHHHHHH
ASVNFGKDYLFLDLMKEEDYLCFLNLIAEADILIMNFKKGDDIKLRVQDDHLHSINPRLI
HEECCCCCEEEEEEECCCCCEEEHHHHHCCCEEEEEECCCCCEEEEEECCCCCCCCCEEE
IGKINGYGEESDRVAYDLVLQGESGFMSINGTQDSGPVKMPVALIDVLAAHHLKEAILLA
EECCCCCCCCCCCEEEEEEEECCCCEEEECCCCCCCCEEHHHHHHHHHHHHHHHHHHHHH
LYHREKNGKGRVVSVSLYDAAVSSLVNQASNYLMTGQVPQRIGSLHPNIAPYGELFQTSD
HHHHCCCCCCCEEEEEHHHHHHHHHHHHHHCEEEECCHHHHHHCCCCCCCCCHHHHCCCC
GALIVLAIGSDRHFVKLCNILGLKDLPGKDEFRHNQNRVRNREQLAALIAEQTEKLQSSE
CCEEEEEECCCCHHHHHHHHHCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
LLEMLHRENIPAGKIMDLKDVFDNERAKSLIRKEVIDDVHTARVTSVVFKQTL
HHHHHHHCCCCCCCEEEHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503; 8125343 [H]