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The map label for this gene is ackA

Identifier: 54020553

GI number: 54020553

Start: 637346

End: 638554

Strand: Reverse

Name: ackA

Synonym: mhp505

Alternate gene names: 54020553

Gene position: 638554-637346 (Counterclockwise)

Preceding gene: 54020554

Following gene: 54020552

Centisome position: 71.53

GC content: 35.24

Gene sequence:

>1209_bases
GTGAAAGCAAAAATTTTAGTAGTAAATGCTGGTTCTTCATCAATTAAATGGCAGATTTTCCAAAAGGAAAATCTTGAATT
ATTAGGTGTAGGCCTAATTGAAAGAATTGGTCTTGAAGATGGTCTAATCAAAATGTCTTTTGGCAAAAAAGACTATAAAT
ACAAAGATAATTTTGCAAATCACAGTCAGGCACTAGCAGTCCAAATTGCCTTTTGGAAGGAAAATCAGCTTGTTGAAAAT
CTTGAAGAATTCCAACTTGTTGGATTTAGAATTGTCCATGGTGGGGCAAGTTTTAAAGCTCCGGCAAAATTAGATCAGAT
GGCAATTTCCAAAATTGAAGCAGCTGCAAAATTTGCGCCATTGCACAATCCCGGCGCCCTGGCAACAATTAAAGCAGTTA
AAGAATTAATTCCAAATGCAAAACTGGCTGCCAGTTTTGATACCGCCTTTCATGGTACTATCCCAAAAATTAATTATACC
TACCCAATTAAGGCCGAAATTGCTGATAAATATGGAATTAGAAAGTACGGTTTTCACGGGATTTCTCATAAATTTATTAC
CACACAAGTTGAAAAAATTTATGACTCTGACAAGGTAAATTTTGTCAATATGCATATTGGTAATGGAATTTCACTCTGCG
CAATTAAAAATTCACAGTCGTTAGATACTTCAATGGGAATGACACCGCTAGCCGGGGTTGCCATGGGGACTCGAAGCGGT
GATATTGATCCATCAATTATACCATATTTGGCAAACGAGGCAAGTTTTTCTTTTAGCGAAATTGATCATTTACTAAATAA
AAATTCCGGACTTTTAGGGCTTTCAGGGGTATCTTCTGATCTTCGTGATGTAATTTCAGCAAAAAATAGTGGTAATTTAG
AGGCAAGTTTTGCCCTTGAAGTTTATGTCCAAAAAATTGTTGATTATCTTGTAAATTATATAAATAAGGTCGGTAAAAAC
ATTAAGGCGCTTGTTTTTACAGGTGGAGTTGGTGAAAATTCAGCTTTTATTCGGTCCCTGGTAATCGAAAAAGTGCAAAT
ACCCGGCCTAAATTTAGTTCTTGACCAAGAAAAAAACTTAAAACCAATCCCAGAATTTGGACCAATTGAGAAAATTTCAG
CTCCTGAATCCGATCTTGATATTTTTGTAATTAAAACTAACGAAGAGCTTTTAATTGCCAAAAATACGATCAGCGTTTGG
GAAAATTAA

Upstream 100 bases:

>100_bases
GAATTAATGCCCCAATTAATGATTTATCCCGGGGATCAACAACTCAAGATGTCTTTAATACCGTGCTAATTAGCGCTCTA
CAAGTTGAAGAAGGTAAATA

Downstream 100 bases:

>100_bases
ATTTATAATTTGATTTATATTATACAACAAAAAATTAGGTTTTTATTAAAAAAAACAAAAACCTAATTTTTTTTAAGTTA
GTATATTAATTTATAGTGTT

Product: acetate kinase

Products: NA

Alternate protein names: Acetokinase [H]

Number of amino acids: Translated: 402; Mature: 402

Protein sequence:

>402_residues
MKAKILVVNAGSSSIKWQIFQKENLELLGVGLIERIGLEDGLIKMSFGKKDYKYKDNFANHSQALAVQIAFWKENQLVEN
LEEFQLVGFRIVHGGASFKAPAKLDQMAISKIEAAAKFAPLHNPGALATIKAVKELIPNAKLAASFDTAFHGTIPKINYT
YPIKAEIADKYGIRKYGFHGISHKFITTQVEKIYDSDKVNFVNMHIGNGISLCAIKNSQSLDTSMGMTPLAGVAMGTRSG
DIDPSIIPYLANEASFSFSEIDHLLNKNSGLLGLSGVSSDLRDVISAKNSGNLEASFALEVYVQKIVDYLVNYINKVGKN
IKALVFTGGVGENSAFIRSLVIEKVQIPGLNLVLDQEKNLKPIPEFGPIEKISAPESDLDIFVIKTNEELLIAKNTISVW
EN

Sequences:

>Translated_402_residues
MKAKILVVNAGSSSIKWQIFQKENLELLGVGLIERIGLEDGLIKMSFGKKDYKYKDNFANHSQALAVQIAFWKENQLVEN
LEEFQLVGFRIVHGGASFKAPAKLDQMAISKIEAAAKFAPLHNPGALATIKAVKELIPNAKLAASFDTAFHGTIPKINYT
YPIKAEIADKYGIRKYGFHGISHKFITTQVEKIYDSDKVNFVNMHIGNGISLCAIKNSQSLDTSMGMTPLAGVAMGTRSG
DIDPSIIPYLANEASFSFSEIDHLLNKNSGLLGLSGVSSDLRDVISAKNSGNLEASFALEVYVQKIVDYLVNYINKVGKN
IKALVFTGGVGENSAFIRSLVIEKVQIPGLNLVLDQEKNLKPIPEFGPIEKISAPESDLDIFVIKTNEELLIAKNTISVW
EN
>Mature_402_residues
MKAKILVVNAGSSSIKWQIFQKENLELLGVGLIERIGLEDGLIKMSFGKKDYKYKDNFANHSQALAVQIAFWKENQLVEN
LEEFQLVGFRIVHGGASFKAPAKLDQMAISKIEAAAKFAPLHNPGALATIKAVKELIPNAKLAASFDTAFHGTIPKINYT
YPIKAEIADKYGIRKYGFHGISHKFITTQVEKIYDSDKVNFVNMHIGNGISLCAIKNSQSLDTSMGMTPLAGVAMGTRSG
DIDPSIIPYLANEASFSFSEIDHLLNKNSGLLGLSGVSSDLRDVISAKNSGNLEASFALEVYVQKIVDYLVNYINKVGKN
IKALVFTGGVGENSAFIRSLVIEKVQIPGLNLVLDQEKNLKPIPEFGPIEKISAPESDLDIFVIKTNEELLIAKNTISVW
EN

Specific function: Anaerobic degradation of L-threonine to propionate. [C]

COG id: COG0282

COG function: function code C; Acetate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetokinase family [H]

Homologues:

Organism=Escherichia coli, GI145693184, Length=397, Percent_Identity=36.272040302267, Blast_Score=253, Evalue=2e-68,
Organism=Escherichia coli, GI1788633, Length=398, Percent_Identity=38.9447236180905, Blast_Score=248, Evalue=4e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000890
- InterPro:   IPR004372 [H]

Pfam domain/function: PF00871 Acetate_kinase [H]

EC number: =2.7.2.1 [H]

Molecular weight: Translated: 44020; Mature: 44020

Theoretical pI: Translated: 7.80; Mature: 7.80

Prosite motif: PS01075 ACETATE_KINASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAKILVVNAGSSSIKWQIFQKENLELLGVGLIERIGLEDGLIKMSFGKKDYKYKDNFAN
CCEEEEEEECCCCCEEEEEEECCCCEEEEEHHHHHCCCCCCEEEEECCCCCCCCCCCCCC
HSQALAVQIAFWKENQLVENLEEFQLVGFRIVHGGASFKAPAKLDQMAISKIEAAAKFAP
CCCEEEEEEEEECCCHHHHHHHHHEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCC
LHNPGALATIKAVKELIPNAKLAASFDTAFHGTIPKINYTYPIKAEIADKYGIRKYGFHG
CCCCCCHHHHHHHHHHCCCCEEEEECCCHHCCCCCCEEEEEEEEHHHHHHCCCHHHCCCC
ISHKFITTQVEKIYDSDKVNFVNMHIGNGISLCAIKNSQSLDTSMGMTPLAGVAMGTRSG
CCCHHHHHHHHHHHCCCCEEEEEEEECCCEEEEEECCCCCCCHHCCCCCHHHEEECCCCC
DIDPSIIPYLANEASFSFSEIDHLLNKNSGLLGLSGVSSDLRDVISAKNSGNLEASFALE
CCCCCHHHEECCCCCCCHHHHHHHHCCCCCEEEECCCCHHHHHHHHCCCCCCCEEEHHHH
VYVQKIVDYLVNYINKVGKNIKALVFTGGVGENSAFIRSLVIEKVQIPGLNLVLDQEKNL
HHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCC
KPIPEFGPIEKISAPESDLDIFVIKTNEELLIAKNTISVWEN
CCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEECEEECCCC
>Mature Secondary Structure
MKAKILVVNAGSSSIKWQIFQKENLELLGVGLIERIGLEDGLIKMSFGKKDYKYKDNFAN
CCEEEEEEECCCCCEEEEEEECCCCEEEEEHHHHHCCCCCCEEEEECCCCCCCCCCCCCC
HSQALAVQIAFWKENQLVENLEEFQLVGFRIVHGGASFKAPAKLDQMAISKIEAAAKFAP
CCCEEEEEEEEECCCHHHHHHHHHEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCC
LHNPGALATIKAVKELIPNAKLAASFDTAFHGTIPKINYTYPIKAEIADKYGIRKYGFHG
CCCCCCHHHHHHHHHHCCCCEEEEECCCHHCCCCCCEEEEEEEEHHHHHHCCCHHHCCCC
ISHKFITTQVEKIYDSDKVNFVNMHIGNGISLCAIKNSQSLDTSMGMTPLAGVAMGTRSG
CCCHHHHHHHHHHHCCCCEEEEEEEECCCEEEEEECCCCCCCHHCCCCCHHHEEECCCCC
DIDPSIIPYLANEASFSFSEIDHLLNKNSGLLGLSGVSSDLRDVISAKNSGNLEASFALE
CCCCCHHHEECCCCCCCHHHHHHHHCCCCCEEEECCCCHHHHHHHHCCCCCCCEEEHHHH
VYVQKIVDYLVNYINKVGKNIKALVFTGGVGENSAFIRSLVIEKVQIPGLNLVLDQEKNL
HHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCC
KPIPEFGPIEKISAPESDLDIFVIKTNEELLIAKNTISVWEN
CCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEECEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11353084 [H]