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The map label for this gene is tpx

Identifier: 54020433

GI number: 54020433

Start: 321607

End: 322098

Strand: Reverse

Name: tpx

Synonym: mhp283

Alternate gene names: 54020433

Gene position: 322098-321607 (Counterclockwise)

Preceding gene: 54020434

Following gene: 54020432

Centisome position: 36.08

GC content: 30.28

Gene sequence:

>492_bases
ATGCAGACAAAATTTAAAAATAAATCATATAATTTAGTATCTTCATTAATTCAGCCAGGGCAAAAACTAGAATTTTCTGT
AAGTGATACAAATTTTGATGTAGTTGAATTTAATTCCTTTGGCAAAACAACATTAATTTCGGTTTTCCCATCAATTAATA
CCAAAATTTGTGATTTTCAAACCGTTTCAATTCGTGACTTATCAGTAAAATATCCACAATTTCGGTTTATTTCAGTTTCC
TTGGACCTTCCTTCTGCGATTGCCCAATGAAAAGATGCTAATTTAGCGGATAATTTAGAAATTTATTCAGATTATCGTCT
CCGCAGTTTTGGTCTTGCAACTGGGTTTTTAATCGAGGATGTATTTTTATTAAATCGCGGGTATATTATTGTTGATTCTG
GTGGTAGAGTTTTAGCCGTTGAGTCTAATTCAGATGTCCATGATCAAATTGATTTTGTTAAATTAGAAGAAAATCTAAAA
AAATTTTCCTAA

Upstream 100 bases:

>100_bases
GATTTAAAAAGTAAAATTATTTCCTAATTTTAATTTTTTTACTTTTTAAATCAAATAAATATTTAATTAAAAAGCAAAAA
AATTTTAGGTAAGGTAAATA

Downstream 100 bases:

>100_bases
TTTTTTTAAGTAAAAAAATAGGAAATTCTAAATTAAAAATTATTTACTTTTAAAAAAGCACTATAAATTACGTGCTTTTT
TATTTTTTAGTAATTTATAT

Product: thiol peroxidase

Products: NA

Alternate protein names: Superoxide-inducible protein 8; SOI8 [H]

Number of amino acids: Translated: 163; Mature: 163

Protein sequence:

>163_residues
MQTKFKNKSYNLVSSLIQPGQKLEFSVSDTNFDVVEFNSFGKTTLISVFPSINTKICDFQTVSIRDLSVKYPQFRFISVS
LDLPSAIAQWKDANLADNLEIYSDYRLRSFGLATGFLIEDVFLLNRGYIIVDSGGRVLAVESNSDVHDQIDFVKLEENLK
KFS

Sequences:

>Translated_163_residues
MQTKFKNKSYNLVSSLIQPGQKLEFSVSDTNFDVVEFNSFGKTTLISVFPSINTKICDFQTVSIRDLSVKYPQFRFISVS
LDLPSAIAQ*KDANLADNLEIYSDYRLRSFGLATGFLIEDVFLLNRGYIIVDSGGRVLAVESNSDVHDQIDFVKLEENLK
KFS
>Mature_163_residues
MQTKFKNKSYNLVSSLIQPGQKLEFSVSDTNFDVVEFNSFGKTTLISVFPSINTKICDFQTVSIRDLSVKYPQFRFISVS
LDLPSAIAQ*KDANLADNLEIYSDYRLRSFGLATGFLIEDVFLLNRGYIIVDSGGRVLAVESNSDVHDQIDFVKLEENLK
KFS

Specific function: Has antioxidant activity. Could remove peroxides or H(2)O(2) [H]

COG id: COG2077

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018219
- InterPro:   IPR002065
- InterPro:   IPR013740
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF08534 Redoxin [H]

EC number: NA

Molecular weight: Translated: 18279; Mature: 18279

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTKFKNKSYNLVSSLIQPGQKLEFSVSDTNFDVVEFNSFGKTTLISVFPSINTKICDFQ
CCCCCCCCCHHHHHHHHCCCCEEEEEECCCCEEEEEECCCCCEEEEEECCCCCCEEECEE
TVSIRDLSVKYPQFRFISVSLDLPSAIAQKDANLADNLEIYSDYRLRSFGLATGFLIEDV
EEEEEEEEECCCCEEEEEEEECCCHHHHHCCCCCCCCEEEEECCEEEECCCCHHHHHHHH
FLLNRGYIIVDSGGRVLAVESNSDVHDQIDFVKLEENLKKFS
HHHCCCEEEEECCCEEEEEECCCCCCHHHHEEEEHHHHHHCC
>Mature Secondary Structure
MQTKFKNKSYNLVSSLIQPGQKLEFSVSDTNFDVVEFNSFGKTTLISVFPSINTKICDFQ
CCCCCCCCCHHHHHHHHCCCCEEEEEECCCCEEEEEECCCCCEEEEEECCCCCCEEECEE
TVSIRDLSVKYPQFRFISVSLDLPSAIAQKDANLADNLEIYSDYRLRSFGLATGFLIEDV
EEEEEEEEECCCCEEEEEEEECCCHHHHHCCCCCCCCEEEEECCEEEECCCCHHHHHHHH
FLLNRGYIIVDSGGRVLAVESNSDVHDQIDFVKLEENLKKFS
HHHCCCEEEEECCCEEEEEECCCCCCHHHHEEEEHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377; 9298659 [H]