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The map label for this gene is mglA

Identifier: 54020270

GI number: 54020270

Start: 780019

End: 781533

Strand: Direct

Name: mglA

Synonym: mhp624

Alternate gene names: 54020270

Gene position: 780019-781533 (Clockwise)

Preceding gene: 54020269

Following gene: 54020271

Centisome position: 87.37

GC content: 32.54

Gene sequence:

>1515_bases
ATGATAAATCAGGATTATGCAATTGAATTTATTCAAGTCTCGAAAAAATTTGGCAGTTTTTATGCCAATTACAAAATAGA
TTTTAAGATTAAAAAAAACACAATTCATGCTCTAATTGGCGAGAATGGTGCTGGAAAATCGACACTTATGTCGACGCTTT
TTGGAATTTATACCCCTGATGAGGGCCAAATTAGAGTCAATGGTAGGCAATCTTTTATTGACAATCCAAATCGCGCAGCA
GATTTTGGAATCGGTATGGTTCACCAACATTTTAAACTTGTTGATGCATATACTAATTTTGAAAACATTATTTTAGGTCA
AGAATTTAGTCATTATGGCATTATCAACCGTGAAACTGCAAGGCAAAAAATCAAAATTTTACAAGAAAAATACAATATTT
CCTTCGATTTAGATCAAAAAACCGGTGATGCCTCTGTTGTTATTAAGCAAAAAATTGAAATTATAAAAATTTTATACCGT
GATTCAGATATTTTAATTTTTGATGAACCAACTGCAATTTTATCACCACAGGAAATTGACTCATTTTTAGAAATTCTGAA
ATTTTTTGTCAAAAATGGGAAAACTATCATTTTTATTTCGCATAAATTATTAGAAATTAAAGAAGTTGCAAATTCGGCCA
CTGTTTTACGGGCAGGAAAAGTCGTTGCTAATTTTGAAAATCTTGAAAATGTTACAATCACGGAAATGGCAGCGGCAATG
GTGGGAAAAACTGTTGTTGAATCAAAAAATACTAGTGAATGCCACTTTGGCCAATTAGGCTTAAAAATTGAAGGTCTTTC
TGCTAAAACTGATAAGGAAATCATTGATTTAGACCTTGAAATTCACAAAGGCGAAATTCTTGCAATTGCCGGAATTGAGG
GAAATGGTCAGTTAGAACTAGAACTTGCTCTTTCCGGTCTTATAGCCTCAAAAGGAAAAATTCTTGTCTATGATAATGAA
AATAAGCCTATAAATCTTGAAAATTTAGGACCTTTAGCCCGTTTTGGTCTAATTTCTTATGTCCCTAGCGATCGCCATAA
ATATGCGATCGTCCTTGATCTACCAAACCTGGATAATTCAATTATTAGAAATTTACGAAACGAAAATTTTGTTAGAAAAA
CTTATGTCAAATCGCAAAAAGTACAAGAATTATATGCAGAAATTGTCAAGAACTTTGATGTTCGCGGTGATTTAATTGGC
TCAAGAAATTCTAGACTTTTATCAGGAGGAAATCAACAAAAATTTGTCTTAGGACGCGAAATTCTAACTCCACATGAAAT
ACTTTTAATTGTTCAGCCAACCCGAGGACTAGATATTGGTGCAATCAATCTCGTCCACCAAATTATTTTAGACCAAAAAC
AGAAAAATAAAGCAATTTTACTAATTTCTTATGAACTTGATGAAGTTTTAGCGCTTGCTGATACAATTTGTGTGCTCAAT
AAAGGCCGAATTTCCAAAAAATTTATGCGCAGCAAAATTGATCGCTATAAAATTGGGCAACTAATGGGGGAATAA

Upstream 100 bases:

>100_bases
TTTAGTTTAATTTAATATAAAATTATATTAAATTAAAAAAATAAAAAATCCGGACTATTTTTGTTCCGGATTTTTTATTT
TTGTGTTACTATTTAATATA

Downstream 100 bases:

>100_bases
AAATGATGAAAAATTTAGTTAATCCGCTGCAATTTTTTTTCAAAAAAATTGACAAAATTAGTCTAAAAAGTTCTTCGGAA
AAGATTTTTTCGACTCTTTG

Product: putative sugar ABC transporter ATP-binding protein

Products: ADP; phosphate; beta-D-galactose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 504; Mature: 504

Protein sequence:

>504_residues
MINQDYAIEFIQVSKKFGSFYANYKIDFKIKKNTIHALIGENGAGKSTLMSTLFGIYTPDEGQIRVNGRQSFIDNPNRAA
DFGIGMVHQHFKLVDAYTNFENIILGQEFSHYGIINRETARQKIKILQEKYNISFDLDQKTGDASVVIKQKIEIIKILYR
DSDILIFDEPTAILSPQEIDSFLEILKFFVKNGKTIIFISHKLLEIKEVANSATVLRAGKVVANFENLENVTITEMAAAM
VGKTVVESKNTSECHFGQLGLKIEGLSAKTDKEIIDLDLEIHKGEILAIAGIEGNGQLELELALSGLIASKGKILVYDNE
NKPINLENLGPLARFGLISYVPSDRHKYAIVLDLPNLDNSIIRNLRNENFVRKTYVKSQKVQELYAEIVKNFDVRGDLIG
SRNSRLLSGGNQQKFVLGREILTPHEILLIVQPTRGLDIGAINLVHQIILDQKQKNKAILLISYELDEVLALADTICVLN
KGRISKKFMRSKIDRYKIGQLMGE

Sequences:

>Translated_504_residues
MINQDYAIEFIQVSKKFGSFYANYKIDFKIKKNTIHALIGENGAGKSTLMSTLFGIYTPDEGQIRVNGRQSFIDNPNRAA
DFGIGMVHQHFKLVDAYTNFENIILGQEFSHYGIINRETARQKIKILQEKYNISFDLDQKTGDASVVIKQKIEIIKILYR
DSDILIFDEPTAILSPQEIDSFLEILKFFVKNGKTIIFISHKLLEIKEVANSATVLRAGKVVANFENLENVTITEMAAAM
VGKTVVESKNTSECHFGQLGLKIEGLSAKTDKEIIDLDLEIHKGEILAIAGIEGNGQLELELALSGLIASKGKILVYDNE
NKPINLENLGPLARFGLISYVPSDRHKYAIVLDLPNLDNSIIRNLRNENFVRKTYVKSQKVQELYAEIVKNFDVRGDLIG
SRNSRLLSGGNQQKFVLGREILTPHEILLIVQPTRGLDIGAINLVHQIILDQKQKNKAILLISYELDEVLALADTICVLN
KGRISKKFMRSKIDRYKIGQLMGE
>Mature_504_residues
MINQDYAIEFIQVSKKFGSFYANYKIDFKIKKNTIHALIGENGAGKSTLMSTLFGIYTPDEGQIRVNGRQSFIDNPNRAA
DFGIGMVHQHFKLVDAYTNFENIILGQEFSHYGIINRETARQKIKILQEKYNISFDLDQKTGDASVVIKQKIEIIKILYR
DSDILIFDEPTAILSPQEIDSFLEILKFFVKNGKTIIFISHKLLEIKEVANSATVLRAGKVVANFENLENVTITEMAAAM
VGKTVVESKNTSECHFGQLGLKIEGLSAKTDKEIIDLDLEIHKGEILAIAGIEGNGQLELELALSGLIASKGKILVYDNE
NKPINLENLGPLARFGLISYVPSDRHKYAIVLDLPNLDNSIIRNLRNENFVRKTYVKSQKVQELYAEIVKNFDVRGDLIG
SRNSRLLSGGNQQKFVLGREILTPHEILLIVQPTRGLDIGAINLVHQIILDQKQKNKAILLISYELDEVLALADTICVLN
KGRISKKFMRSKIDRYKIGQLMGE

Specific function: Part Of The Binding-Protein-Dependent Transport System For Galactosides. Probably Responsible For Energy Coupling To The Transport System. [C]

COG id: COG3845

COG function: function code R; ABC-type uncharacterized transport systems, ATPase components

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI105990541, Length=197, Percent_Identity=24.8730964467005, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI31657092, Length=194, Percent_Identity=29.3814432989691, Blast_Score=72, Evalue=2e-12,
Organism=Escherichia coli, GI1788472, Length=486, Percent_Identity=33.5390946502058, Blast_Score=240, Evalue=2e-64,
Organism=Escherichia coli, GI1790190, Length=482, Percent_Identity=31.7427385892116, Blast_Score=233, Evalue=2e-62,
Organism=Escherichia coli, GI1788210, Length=492, Percent_Identity=28.8617886178862, Blast_Score=214, Evalue=9e-57,
Organism=Escherichia coli, GI1787792, Length=492, Percent_Identity=30.6910569105691, Blast_Score=211, Evalue=1e-55,
Organism=Escherichia coli, GI1789991, Length=508, Percent_Identity=31.496062992126, Blast_Score=209, Evalue=3e-55,
Organism=Escherichia coli, GI1788897, Length=484, Percent_Identity=29.5454545454545, Blast_Score=207, Evalue=1e-54,
Organism=Escherichia coli, GI48995001, Length=485, Percent_Identity=30.1030927835052, Blast_Score=206, Evalue=2e-54,
Organism=Escherichia coli, GI1790525, Length=501, Percent_Identity=28.1437125748503, Blast_Score=206, Evalue=2e-54,
Organism=Escherichia coli, GI48994943, Length=222, Percent_Identity=26.5765765765766, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1786872, Length=219, Percent_Identity=28.7671232876712, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI87081782, Length=218, Percent_Identity=29.3577981651376, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1790467, Length=224, Percent_Identity=25.4464285714286, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1786398, Length=200, Percent_Identity=27, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1787029, Length=220, Percent_Identity=26.3636363636364, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1788225, Length=230, Percent_Identity=25.6521739130435, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1786319, Length=223, Percent_Identity=28.2511210762332, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1788761, Length=223, Percent_Identity=28.2511210762332, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1789672, Length=216, Percent_Identity=25.462962962963, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1789864, Length=224, Percent_Identity=23.6607142857143, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1786253, Length=222, Percent_Identity=23.4234234234234, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1786654, Length=201, Percent_Identity=30.3482587064677, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1789032, Length=225, Percent_Identity=27.1111111111111, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1786803, Length=225, Percent_Identity=26.6666666666667, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1787089, Length=211, Percent_Identity=23.2227488151659, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788644, Length=197, Percent_Identity=25.8883248730964, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87082268, Length=216, Percent_Identity=25, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1786703, Length=185, Percent_Identity=27.027027027027, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1790544, Length=223, Percent_Identity=25.1121076233184, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71983523, Length=195, Percent_Identity=29.2307692307692, Blast_Score=72, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI71983516, Length=195, Percent_Identity=29.2307692307692, Blast_Score=72, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI71983510, Length=195, Percent_Identity=29.2307692307692, Blast_Score=72, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6321081, Length=271, Percent_Identity=26.9372693726937, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI281363262, Length=206, Percent_Identity=32.0388349514563, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24653245, Length=206, Percent_Identity=32.0388349514563, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 56669; Mature: 56669

Theoretical pI: Translated: 8.52; Mature: 8.52

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINQDYAIEFIQVSKKFGSFYANYKIDFKIKKNTIHALIGENGAGKSTLMSTLFGIYTPD
CCCCCCEEHHHHHHHHHCCEEEEEEEEEEEECCEEEEEECCCCCCHHHHHHHHHHCCCCC
EGQIRVNGRQSFIDNPNRAADFGIGMVHQHFKLVDAYTNFENIILGQEFSHYGIINRETA
CCEEEECCCHHCCCCCCCHHHHCHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCHHHH
RQKIKILQEKYNISFDLDQKTGDASVVIKQKIEIIKILYRDSDILIFDEPTAILSPQEID
HHHHHHHHHHCCCEEEECCCCCCCEEEEHHHHEEEEEEEECCCEEEECCCCCCCCHHHHH
SFLEILKFFVKNGKTIIFISHKLLEIKEVANSATVLRAGKVVANFENLENVTITEMAAAM
HHHHHHHHHHHCCCEEEEEECHHHHHHHHHCCHHEEECCHHEECHHCCCCCHHHHHHHHH
VGKTVVESKNTSECHFGQLGLKIEGLSAKTDKEIIDLDLEIHKGEILAIAGIEGNGQLEL
HHHHHHCCCCCCCCEECCCCEEEECCCCCCCCEEEEEEEEEECCCEEEEEEECCCCEEEE
ELALSGLIASKGKILVYDNENKPINLENLGPLARFGLISYVPSDRHKYAIVLDLPNLDNS
EEEEEHHHCCCCEEEEEECCCCCCCHHCCCCHHHHHHHCCCCCCCCCEEEEEECCCCCHH
IIRNLRNENFVRKTYVKSQKVQELYAEIVKNFDVRGDLIGSRNSRLLSGGNQQKFVLGRE
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCEEECCCCCCEEEECHH
ILTPHEILLIVQPTRGLDIGAINLVHQIILDQKQKNKAILLISYELDEVLALADTICVLN
HCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCEEEEEEECHHHHHHHHHHHHEEC
KGRISKKFMRSKIDRYKIGQLMGE
CCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MINQDYAIEFIQVSKKFGSFYANYKIDFKIKKNTIHALIGENGAGKSTLMSTLFGIYTPD
CCCCCCEEHHHHHHHHHCCEEEEEEEEEEEECCEEEEEECCCCCCHHHHHHHHHHCCCCC
EGQIRVNGRQSFIDNPNRAADFGIGMVHQHFKLVDAYTNFENIILGQEFSHYGIINRETA
CCEEEECCCHHCCCCCCCHHHHCHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCHHHH
RQKIKILQEKYNISFDLDQKTGDASVVIKQKIEIIKILYRDSDILIFDEPTAILSPQEID
HHHHHHHHHHCCCEEEECCCCCCCEEEEHHHHEEEEEEEECCCEEEECCCCCCCCHHHHH
SFLEILKFFVKNGKTIIFISHKLLEIKEVANSATVLRAGKVVANFENLENVTITEMAAAM
HHHHHHHHHHHCCCEEEEEECHHHHHHHHHCCHHEEECCHHEECHHCCCCCHHHHHHHHH
VGKTVVESKNTSECHFGQLGLKIEGLSAKTDKEIIDLDLEIHKGEILAIAGIEGNGQLEL
HHHHHHCCCCCCCCEECCCCEEEECCCCCCCCEEEEEEEEEECCCEEEEEEECCCCEEEE
ELALSGLIASKGKILVYDNENKPINLENLGPLARFGLISYVPSDRHKYAIVLDLPNLDNS
EEEEEHHHCCCCEEEEEECCCCCCCHHCCCCHHHHHHHCCCCCCCCCEEEEEECCCCCHH
IIRNLRNENFVRKTYVKSQKVQELYAEIVKNFDVRGDLIGSRNSRLLSGGNQQKFVLGRE
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCEEECCCCCCEEEECHH
ILTPHEILLIVQPTRGLDIGAINLVHQIILDQKQKNKAILLISYELDEVLALADTICVLN
HCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCEEEEEEECHHHHHHHHHHHHEEC
KGRISKKFMRSKIDRYKIGQLMGE
CCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; beta-D-galactose [Periplasm]; H2O [C]

Specific reaction: ATP + beta-D-galactose [Periplasm] + H2O = ADP + phosphate + beta-D-galactose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9274030; 9384377 [H]