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The map label for this gene is ykpA [H]

Identifier: 54020065

GI number: 54020065

Start: 207735

End: 209351

Strand: Direct

Name: ykpA [H]

Synonym: mhp171

Alternate gene names: 54020065

Gene position: 207735-209351 (Clockwise)

Preceding gene: 54020064

Following gene: 54020066

Centisome position: 23.27

GC content: 33.09

Gene sequence:

>1617_bases
ATGCTAGAAGTTAGAGAATTATCGAAAATCTTTGCTGATAAAACTTTATTCCAAAATGTAAATTTAAAATTTACAGAAGG
AAATACTTATGGCATTATCGGCGCAAATGGTGCTGGGAAATCCACTTTTTTGAAAATTTTAGCAGGACTTATTGAACCAA
GTTCAGGCTCTATTCATATCTCACAAAACCAAAGAATTTCTGTTCTATCACAGAATCATTTTGAGTTTGATGAATTCAAT
GTCACCGATGTTGTAATAATGGGGAACGAAAAATTATACCAAATCCAACAAGAAAAAGATCAAATTTATGCAAATCCTGA
TGCAACTGAAGCAGATTATAACCGCGCTGGCGAACTTGAGGAAAAATTCGGGCTCCTAGGAGGATGAAGCGCGGAAAATG
ATGCCCAAATTTTGCTCTCTGCTCTTGAAATTCCCAAAAAATACTGAAATAGTAAGATGTCAGATTTAAAATCCGGCTAT
AAAGTCAAAGTTCTCCTTGCAAAAGCACTTTTTGGCAACCCCGATATTTTAATAATGGATGAGCCGACCAACCACCTTGA
TTTTAAAGCGATTAAATGACTGAAAGAATTTCTAATTAATTATAAAAACGTTGTTCTAATTGTTAGCCACGACAGCGATT
TTTTAGACCAAGTTTGCACACATACAGTTGATATTGACTATGGCGAGATAAAAATTTTTACCGGAAATTACAGTTTTTGG
AAACAATCATCAGAACTACTAAAGGAACTCCAGAAAAATGCTAATGCTAAAAAAGAGGAGCAAATCGCCAAATTAGAAGC
ATTTATTGCCAAATTTTCAGCAAATGCTTCAAAATCAGCCCAGGCAACTTCACGGAAAAAATCACTTGAAAAAATCCAGT
TAGAAGAAATTAAACCCTCCTCACGAAAATATCCTTATATTCGTTTTGGAGTTTTCCCGCGGCCGGGAAAACAAGTTTTA
AATGTTGAAAACTTAAGTTATAAAAATCCACTTACAGGTAATTTTTTATTTCAAAATATTTCTTTTAATCTTTTACCAGG
TCAAAAAATGGTAATTTTTGCCGAAGATGATTTAGTTAAAACTAAATTACTTGAAATTTTAACAGGAAAAGAAATGCCAA
CTTCAGGAACAATCAGTTGAGGTTCGACAATCAAATTTGACTATCTTCCAGCAAATAATGATAGTTTTTTTAACGGCGAT
CTTGATTTATTATCCTGAATTTCACAATGGCCAAGTCTTAATTTACAACCAGAAAACAAGGATAATTCTACCCAGAGAAT
GCGAGGTTTTCTTGGAAGGATGTTCTTTAATGGCGATCAAGTTTTTAAAAAAGTTTCAGTTACATCTGGAGGTGAAAAAG
TTCGTCTGATGTTCGCAAAAATGATGTTAAGCGAGTCAAATTTCCTACTTTTTGACCAACCACTTAATCATTTAGACTCT
GAATCGATTGATTCATTCATTGAAGCTCTAAAACTTTATGACTCAGGGGTAATTTTTACCACTTTTAATCTTGCTTTGAT
CAACGAAGTTGCTAATGTTATTTTAGATATCAAAGAAGATAGTGCAATTTTTTTTCAAGGGAATTTGGCTGAATATGAGA
AAAAAATAGGAATTTAG

Upstream 100 bases:

>100_bases
ACAATAAATAAATGGAAAAAGATGAAAATTTAAACTAGTTATTTTTCAATTTTATTGTATAATATTATACCATAAAAAAT
TAGAATTAAAGGAAAATAAA

Downstream 100 bases:

>100_bases
CTTTAATTTTTTCTATTTTTTATTTTTTTTAGGAGAATTTAAGTTGCTTTCTGATACAATTTGTGCAATCGCTTCTGGGC
AAATAAACCAAGCAATTTCA

Product: ABC transporter ATP binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 538; Mature: 538

Protein sequence:

>538_residues
MLEVRELSKIFADKTLFQNVNLKFTEGNTYGIIGANGAGKSTFLKILAGLIEPSSGSIHISQNQRISVLSQNHFEFDEFN
VTDVVIMGNEKLYQIQQEKDQIYANPDATEADYNRAGELEEKFGLLGGWSAENDAQILLSALEIPKKYWNSKMSDLKSGY
KVKVLLAKALFGNPDILIMDEPTNHLDFKAIKWLKEFLINYKNVVLIVSHDSDFLDQVCTHTVDIDYGEIKIFTGNYSFW
KQSSELLKELQKNANAKKEEQIAKLEAFIAKFSANASKSAQATSRKKSLEKIQLEEIKPSSRKYPYIRFGVFPRPGKQVL
NVENLSYKNPLTGNFLFQNISFNLLPGQKMVIFAEDDLVKTKLLEILTGKEMPTSGTISWGSTIKFDYLPANNDSFFNGD
LDLLSWISQWPSLNLQPENKDNSTQRMRGFLGRMFFNGDQVFKKVSVTSGGEKVRLMFAKMMLSESNFLLFDQPLNHLDS
ESIDSFIEALKLYDSGVIFTTFNLALINEVANVILDIKEDSAIFFQGNLAEYEKKIGI

Sequences:

>Translated_538_residues
MLEVRELSKIFADKTLFQNVNLKFTEGNTYGIIGANGAGKSTFLKILAGLIEPSSGSIHISQNQRISVLSQNHFEFDEFN
VTDVVIMGNEKLYQIQQEKDQIYANPDATEADYNRAGELEEKFGLLGG*SAENDAQILLSALEIPKKY*NSKMSDLKSGY
KVKVLLAKALFGNPDILIMDEPTNHLDFKAIK*LKEFLINYKNVVLIVSHDSDFLDQVCTHTVDIDYGEIKIFTGNYSFW
KQSSELLKELQKNANAKKEEQIAKLEAFIAKFSANASKSAQATSRKKSLEKIQLEEIKPSSRKYPYIRFGVFPRPGKQVL
NVENLSYKNPLTGNFLFQNISFNLLPGQKMVIFAEDDLVKTKLLEILTGKEMPTSGTIS*GSTIKFDYLPANNDSFFNGD
LDLLS*ISQWPSLNLQPENKDNSTQRMRGFLGRMFFNGDQVFKKVSVTSGGEKVRLMFAKMMLSESNFLLFDQPLNHLDS
ESIDSFIEALKLYDSGVIFTTFNLALINEVANVILDIKEDSAIFFQGNLAEYEKKIGI
>Mature_538_residues
MLEVRELSKIFADKTLFQNVNLKFTEGNTYGIIGANGAGKSTFLKILAGLIEPSSGSIHISQNQRISVLSQNHFEFDEFN
VTDVVIMGNEKLYQIQQEKDQIYANPDATEADYNRAGELEEKFGLLGG*SAENDAQILLSALEIPKKY*NSKMSDLKSGY
KVKVLLAKALFGNPDILIMDEPTNHLDFKAIK*LKEFLINYKNVVLIVSHDSDFLDQVCTHTVDIDYGEIKIFTGNYSFW
KQSSELLKELQKNANAKKEEQIAKLEAFIAKFSANASKSAQATSRKKSLEKIQLEEIKPSSRKYPYIRFGVFPRPGKQVL
NVENLSYKNPLTGNFLFQNISFNLLPGQKMVIFAEDDLVKTKLLEILTGKEMPTSGTIS*GSTIKFDYLPANNDSFFNGD
LDLLS*ISQWPSLNLQPENKDNSTQRMRGFLGRMFFNGDQVFKKVSVTSGGEKVRLMFAKMMLSESNFLLFDQPLNHLDS
ESIDSFIEALKLYDSGVIFTTFNLALINEVANVILDIKEDSAIFFQGNLAEYEKKIGI

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI10947137, Length=533, Percent_Identity=28.5178236397749, Blast_Score=194, Evalue=2e-49,
Organism=Homo sapiens, GI27881506, Length=533, Percent_Identity=28.5178236397749, Blast_Score=194, Evalue=2e-49,
Organism=Homo sapiens, GI148612853, Length=533, Percent_Identity=26.078799249531, Blast_Score=182, Evalue=9e-46,
Organism=Homo sapiens, GI10947135, Length=539, Percent_Identity=28.3858998144712, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI69354671, Length=539, Percent_Identity=28.3858998144712, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI255708477, Length=176, Percent_Identity=28.4090909090909, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1787041, Length=538, Percent_Identity=41.0780669144981, Blast_Score=416, Evalue=1e-117,
Organism=Escherichia coli, GI2367384, Length=536, Percent_Identity=29.2910447761194, Blast_Score=209, Evalue=3e-55,
Organism=Escherichia coli, GI1789751, Length=530, Percent_Identity=28.6792452830189, Blast_Score=206, Evalue=4e-54,
Organism=Escherichia coli, GI1787182, Length=518, Percent_Identity=26.8339768339768, Blast_Score=152, Evalue=7e-38,
Organism=Escherichia coli, GI1786398, Length=246, Percent_Identity=26.4227642276423, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1787029, Length=235, Percent_Identity=28.0851063829787, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1788225, Length=249, Percent_Identity=26.5060240963855, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI48994997, Length=222, Percent_Identity=24.3243243243243, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI1786319, Length=241, Percent_Identity=22.8215767634855, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI48994943, Length=194, Percent_Identity=26.8041237113402, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1788210, Length=211, Percent_Identity=28.9099526066351, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI87081791, Length=224, Percent_Identity=26.3392857142857, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1788897, Length=217, Percent_Identity=25.3456221198157, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI48994883, Length=234, Percent_Identity=25.2136752136752, Blast_Score=64, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17555318, Length=545, Percent_Identity=25.6880733944954, Blast_Score=192, Evalue=4e-49,
Organism=Caenorhabditis elegans, GI17553372, Length=543, Percent_Identity=29.2817679558011, Blast_Score=187, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI17559834, Length=542, Percent_Identity=25.830258302583, Blast_Score=165, Evalue=5e-41,
Organism=Caenorhabditis elegans, GI193208177, Length=218, Percent_Identity=26.605504587156, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6320874, Length=547, Percent_Identity=29.981718464351, Blast_Score=208, Evalue=1e-54,
Organism=Saccharomyces cerevisiae, GI6321121, Length=549, Percent_Identity=27.8688524590164, Blast_Score=170, Evalue=7e-43,
Organism=Saccharomyces cerevisiae, GI6324314, Length=378, Percent_Identity=24.3386243386243, Blast_Score=98, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6323278, Length=383, Percent_Identity=23.2375979112272, Blast_Score=93, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6325030, Length=244, Percent_Identity=28.2786885245902, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24642252, Length=545, Percent_Identity=28.6238532110092, Blast_Score=210, Evalue=2e-54,
Organism=Drosophila melanogaster, GI18859989, Length=545, Percent_Identity=28.6238532110092, Blast_Score=210, Evalue=2e-54,
Organism=Drosophila melanogaster, GI24666836, Length=533, Percent_Identity=28.7054409005629, Blast_Score=204, Evalue=9e-53,
Organism=Drosophila melanogaster, GI24641342, Length=548, Percent_Identity=27.7372262773723, Blast_Score=172, Evalue=6e-43,
Organism=Drosophila melanogaster, GI116007184, Length=245, Percent_Identity=24.8979591836735, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI221500365, Length=245, Percent_Identity=24.8979591836735, Blast_Score=72, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 59891; Mature: 59891

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEVRELSKIFADKTLFQNVNLKFTEGNTYGIIGANGAGKSTFLKILAGLIEPSSGSIHI
CCCHHHHHHHHHHHHHHHCCCEEEECCCEEEEEECCCCCHHHHHHHHHHHCCCCCCEEEE
SQNQRISVLSQNHFEFDEFNVTDVVIMGNEKLYQIQQEKDQIYANPDATEADYNRAGELE
CCCCEEEEEECCCCCCCCCCCEEEEEECCCHHEEEHHCCCCEECCCCCCCCCCCCCCCHH
EKFGLLGGSAENDAQILLSALEIPKKYNSKMSDLKSGYKVKVLLAKALFGNPDILIMDEP
HHHCCCCCCCCCHHHHHHHHHHCCHHHCCHHHHHHCCCEEEEEEEEHHCCCCCEEEEECC
TNHLDFKAIKLKEFLINYKNVVLIVSHDSDFLDQVCTHTVDIDYGEIKIFTGNYSFWKQS
CCCCCEEHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHEEECCCCEEEEEECCCHHHHHH
SELLKELQKNANAKKEEQIAKLEAFIAKFSANASKSAQATSRKKSLEKIQLEEIKPSSRK
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
YPYIRFGVFPRPGKQVLNVENLSYKNPLTGNFLFQNISFNLLPGQKMVIFAEDDLVKTKL
CCEEEEECCCCCCHHEEEECCCCCCCCCCCCEEEECCEEEECCCCEEEEEECCCHHHHHH
LEILTGKEMPTSGTISGSTIKFDYLPANNDSFFNGDLDLLSISQWPSLNLQPENKDNSTQ
HHHHCCCCCCCCCCCCCCEEEEEEEECCCCCEECCCEEEEEECCCCCCCCCCCCCCCHHH
RMRGFLGRMFFNGDQVFKKVSVTSGGEKVRLMFAKMMLSESNFLLFDQPLNHLDSESIDS
HHHHHHHHHHCCHHHHHHEEEECCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHH
FIEALKLYDSGVIFTTFNLALINEVANVILDIKEDSAIFFQGNLAEYEKKIGI
HHHHHHHHCCCEEEEEHHHHHHHHHHHHEEEECCCCEEEEECCHHHHHHHCCC
>Mature Secondary Structure
MLEVRELSKIFADKTLFQNVNLKFTEGNTYGIIGANGAGKSTFLKILAGLIEPSSGSIHI
CCCHHHHHHHHHHHHHHHCCCEEEECCCEEEEEECCCCCHHHHHHHHHHHCCCCCCEEEE
SQNQRISVLSQNHFEFDEFNVTDVVIMGNEKLYQIQQEKDQIYANPDATEADYNRAGELE
CCCCEEEEEECCCCCCCCCCCEEEEEECCCHHEEEHHCCCCEECCCCCCCCCCCCCCCHH
EKFGLLGGSAENDAQILLSALEIPKKYNSKMSDLKSGYKVKVLLAKALFGNPDILIMDEP
HHHCCCCCCCCCHHHHHHHHHHCCHHHCCHHHHHHCCCEEEEEEEEHHCCCCCEEEEECC
TNHLDFKAIKLKEFLINYKNVVLIVSHDSDFLDQVCTHTVDIDYGEIKIFTGNYSFWKQS
CCCCCEEHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHEEECCCCEEEEEECCCHHHHHH
SELLKELQKNANAKKEEQIAKLEAFIAKFSANASKSAQATSRKKSLEKIQLEEIKPSSRK
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
YPYIRFGVFPRPGKQVLNVENLSYKNPLTGNFLFQNISFNLLPGQKMVIFAEDDLVKTKL
CCEEEEECCCCCCHHEEEECCCCCCCCCCCCEEEECCEEEECCCCEEEEEECCCHHHHHH
LEILTGKEMPTSGTISGSTIKFDYLPANNDSFFNGDLDLLSISQWPSLNLQPENKDNSTQ
HHHHCCCCCCCCCCCCCCEEEEEEEECCCCCEECCCEEEEEECCCCCCCCCCCCCCCHHH
RMRGFLGRMFFNGDQVFKKVSVTSGGEKVRLMFAKMMLSESNFLLFDQPLNHLDSESIDS
HHHHHHHHHHCCHHHHHHEEEECCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHH
FIEALKLYDSGVIFTTFNLALINEVANVILDIKEDSAIFFQGNLAEYEKKIGI
HHHHHHHHCCCEEEEEHHHHHHHHHHHHEEEECCCCEEEEECCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]