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The map label for this gene is avtA [H]

Identifier: 52787914

GI number: 52787914

Start: 4074155

End: 4075432

Strand: Reverse

Name: avtA [H]

Synonym: BLi04237

Alternate gene names: 52787914

Gene position: 4075432-4074155 (Counterclockwise)

Preceding gene: 52787915

Following gene: 52787908

Centisome position: 96.51

GC content: 49.61

Gene sequence:

>1278_bases
GTGAAGCCGCCATTAAGCAAAATCGGAGAGAAAATGATTGAGAAAACAGGGGTCAGGGCTGTGATGAGCGATATTCAGGA
AGTCCTGGCCGGCGGTGAACGGTCATACATTAATTTAAGTGCGGGCAATCCGATGATTTTGCCCGGCGTGTCAGCCATGT
GGAAGTCGGCTCTTGCCGATCTCCTTGACGATGACAGGTTTTCTTCGGTGATCGGCCAATACGGATCGAGCTATGGAACC
GATGAACTGATTGCAAGTGTTGTCCGCTTCTTTTCAGAGCGGTATAGCGCCGGCATTCGAAAAGAGAACGTGTTGATTAC
AGCCGGAAGCCAGCAGCTGTTTTTTCTGGCGATCAATTCGTTTTGCGGAATGGGAAGCGGATCTGTGATGAAAAAAGCCT
TGATCCCGATGCTGCCTGACTATTCGGGATACAGCGGGGCGGCACTGGAGCGGGAGATGATTGAGGGGATCCCTCCGCTC
ATATCGAAATTGGATGATCATACGTTTCGATATGAGCTCGACCGTAAGGGGTTTTTAGAGAGGATGCGCATCGGTGCTGT
CTTGCTATCGCGCCCGAACAATCCTTGCGGAAACATCTTGCCTAAAGAAGATGTAGCATTCATTTCAGACGCATGCCGAG
AAGCGAATGTTCCGCTGTTCATTGATTCCGCATATGCTCCGCCTTTTCCGGCGATTCACTTTATCGACATGGAACCGATT
TTCAACGAGCAGATCATTCACTGTATGAGCCTTTCAAAAGCCGGCCTGCCTGGCGAAAGGATCGGAATCGCCATCGGGCC
GTCCCGGTATATTCAGGCAATGGAAGCTTTTCAGTCGAATGCGGCGATCCATTCTTCAAGGCTGGGGCAGTATATGGCTG
CATCAGTATTGAATGACGGGCGCCTCGCCGACGTGTCGCTGAATGAAGTCAGGCCATATTACCGCAATAAATTCATGCTG
CTCAAGGAAACGCTTTTATGCAAGATGCCTGAAGACATCAAATGGTATCTGCATCAAGGGGAAGGATCGCTTTTCGGATG
GCTGTGGTTTGAAGACCTGCCGGTGACCGATGCAGCGCTGTATGAGTATATGAAAGCGGATGGAGTCATTATCGTTCCCG
GATCATCTTTCTTTCACCGTCAATCCCGGCGCCTGGCGCATTCACACCAGTGTATACGAATCAGCCTAACCGCGGCGGAT
GAAGATATTATAAGGGGAATCGATGTTTTAGCTAAAATTGCGAAGGGTGTATATGAGAAACAGGTTGAATACTTATAA

Upstream 100 bases:

>100_bases
AAGGCGAGCGATTCAGCGTCCCGGAACAGTATTTCATTGACGAGATCAATAAGAAAATCGAAACCGCCCGTCTTCGATTT
GAACGGGAGAGACTGGAAGC

Downstream 100 bases:

>100_bases
AAAAACAGGGGCTAAAAGCAAGCCCCTGTTTTATTCGTCAATCCCTCCGCCGGCATTGGCCTTTCTTTTTCTGCGCCTTG
CCGTTGTCAAGATCAAAATA

Product: valine--pyruvate transaminase

Products: NA

Alternate protein names: Alanine--valine transaminase; Transaminase C [H]

Number of amino acids: Translated: 425; Mature: 425

Protein sequence:

>425_residues
MKPPLSKIGEKMIEKTGVRAVMSDIQEVLAGGERSYINLSAGNPMILPGVSAMWKSALADLLDDDRFSSVIGQYGSSYGT
DELIASVVRFFSERYSAGIRKENVLITAGSQQLFFLAINSFCGMGSGSVMKKALIPMLPDYSGYSGAALEREMIEGIPPL
ISKLDDHTFRYELDRKGFLERMRIGAVLLSRPNNPCGNILPKEDVAFISDACREANVPLFIDSAYAPPFPAIHFIDMEPI
FNEQIIHCMSLSKAGLPGERIGIAIGPSRYIQAMEAFQSNAAIHSSRLGQYMAASVLNDGRLADVSLNEVRPYYRNKFML
LKETLLCKMPEDIKWYLHQGEGSLFGWLWFEDLPVTDAALYEYMKADGVIIVPGSSFFHRQSRRLAHSHQCIRISLTAAD
EDIIRGIDVLAKIAKGVYEKQVEYL

Sequences:

>Translated_425_residues
MKPPLSKIGEKMIEKTGVRAVMSDIQEVLAGGERSYINLSAGNPMILPGVSAMWKSALADLLDDDRFSSVIGQYGSSYGT
DELIASVVRFFSERYSAGIRKENVLITAGSQQLFFLAINSFCGMGSGSVMKKALIPMLPDYSGYSGAALEREMIEGIPPL
ISKLDDHTFRYELDRKGFLERMRIGAVLLSRPNNPCGNILPKEDVAFISDACREANVPLFIDSAYAPPFPAIHFIDMEPI
FNEQIIHCMSLSKAGLPGERIGIAIGPSRYIQAMEAFQSNAAIHSSRLGQYMAASVLNDGRLADVSLNEVRPYYRNKFML
LKETLLCKMPEDIKWYLHQGEGSLFGWLWFEDLPVTDAALYEYMKADGVIIVPGSSFFHRQSRRLAHSHQCIRISLTAAD
EDIIRGIDVLAKIAKGVYEKQVEYL
>Mature_425_residues
MKPPLSKIGEKMIEKTGVRAVMSDIQEVLAGGERSYINLSAGNPMILPGVSAMWKSALADLLDDDRFSSVIGQYGSSYGT
DELIASVVRFFSERYSAGIRKENVLITAGSQQLFFLAINSFCGMGSGSVMKKALIPMLPDYSGYSGAALEREMIEGIPPL
ISKLDDHTFRYELDRKGFLERMRIGAVLLSRPNNPCGNILPKEDVAFISDACREANVPLFIDSAYAPPFPAIHFIDMEPI
FNEQIIHCMSLSKAGLPGERIGIAIGPSRYIQAMEAFQSNAAIHSSRLGQYMAASVLNDGRLADVSLNEVRPYYRNKFML
LKETLLCKMPEDIKWYLHQGEGSLFGWLWFEDLPVTDAALYEYMKADGVIIVPGSSFFHRQSRRLAHSHQCIRISLTAAD
EDIIRGIDVLAKIAKGVYEKQVEYL

Specific function: Unknown

COG id: COG3977

COG function: function code E; Alanine-alpha-ketoisovalerate (or valine-pyruvate) aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI48994949, Length=408, Percent_Identity=31.6176470588235, Blast_Score=245, Evalue=4e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.66 [H]

Molecular weight: Translated: 47233; Mature: 47233

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPPLSKIGEKMIEKTGVRAVMSDIQEVLAGGERSYINLSAGNPMILPGVSAMWKSALAD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCEEECCHHHHHHHHHHH
LLDDDRFSSVIGQYGSSYGTDELIASVVRFFSERYSAGIRKENVLITAGSQQLFFLAINS
HHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCEEEEEEEHH
FCGMGSGSVMKKALIPMLPDYSGYSGAALEREMIEGIPPLISKLDDHTFRYELDRKGFLE
HCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCHHHHHHCCCCEEEECCHHHHHH
RMRIGAVLLSRPNNPCGNILPKEDVAFISDACREANVPLFIDSAYAPPFPAIHFIDMEPI
HHHHHHHEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCCEEEEECCCH
FNEQIIHCMSLSKAGLPGERIGIAIGPSRYIQAMEAFQSNAAIHSSRLGQYMAASVLNDG
HHHHHHHHHHHHCCCCCCCCEEEEECHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCC
RLADVSLNEVRPYYRNKFMLLKETLLCKMPEDIKWYLHQGEGSLFGWLWFEDLPVTDAAL
CEEECCHHHCCHHHHCHHHHHHHHHHHCCCHHHEEHEECCCCCEEEEEEECCCCCHHHHH
YEYMKADGVIIVPGSSFFHRQSRRLAHSHQCIRISLTAADEDIIRGIDVLAKIAKGVYEK
HHHHHCCCEEEECCCHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHH
QVEYL
HHCCC
>Mature Secondary Structure
MKPPLSKIGEKMIEKTGVRAVMSDIQEVLAGGERSYINLSAGNPMILPGVSAMWKSALAD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCEEECCHHHHHHHHHHH
LLDDDRFSSVIGQYGSSYGTDELIASVVRFFSERYSAGIRKENVLITAGSQQLFFLAINS
HHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCEEEEEEEHH
FCGMGSGSVMKKALIPMLPDYSGYSGAALEREMIEGIPPLISKLDDHTFRYELDRKGFLE
HCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCHHHHHHCCCCEEEECCHHHHHH
RMRIGAVLLSRPNNPCGNILPKEDVAFISDACREANVPLFIDSAYAPPFPAIHFIDMEPI
HHHHHHHEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCCEEEEECCCH
FNEQIIHCMSLSKAGLPGERIGIAIGPSRYIQAMEAFQSNAAIHSSRLGQYMAASVLNDG
HHHHHHHHHHHHCCCCCCCCEEEEECHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCC
RLADVSLNEVRPYYRNKFMLLKETLLCKMPEDIKWYLHQGEGSLFGWLWFEDLPVTDAAL
CEEECCHHHCCHHHHCHHHHHHHHHHHCCCHHHEEHEECCCCCEEEEEEECCCCCHHHHH
YEYMKADGVIIVPGSSFFHRQSRRLAHSHQCIRISLTAADEDIIRGIDVLAKIAKGVYEK
HHHHHCCCEEEECCCHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHH
QVEYL
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2825136; 8041620; 9278503 [H]