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The map label for this gene is licC [H]

Identifier: 52787846

GI number: 52787846

Start: 3996795

End: 3998114

Strand: Reverse

Name: licC [H]

Synonym: BLi04169

Alternate gene names: 52787846

Gene position: 3998114-3996795 (Counterclockwise)

Preceding gene: 52787847

Following gene: 52787845

Centisome position: 94.68

GC content: 49.32

Gene sequence:

>1320_bases
ATGAGCAGGATGGCGAAGGTGACTGAGATGTTTGAGCGGGTCGCTTTTAAAATTACAAGTTTCAAATATATCATGGTCAT
TAAGTCGGCGTTTGTCACACTGATGCCGGTCATCATTGCCGGGGCGTTTGCGGTTTTGATGCAGAATATGGTGATGAGCC
CCGAGACGGGACTTGCGGTTTTCAGGCCTTTTCGGTTCTTGTCTGCGCTTGAGCCGATTATGGCGTCAATCAATTATGCG
ACGCTGAACTTTATTACGATCGGCGCGGTGTTTTTGATCGGGATTGAGCTCGGGAAGCTGAATGGGCATGAATCGTTTTT
TCCCGGCTTGATGGCGCTCATGTCCTATATCTCTGTCATTCCATCGGCGGTGCTGTTGGAAGTGAACGGTTCGATGCAGG
AAGTGGTTAACGTGCTGGCCAAGGAATTTACGGATCCGAAGTCGCTGTTTTTGGGGATGTTTATTTCGATTGTGTCTGTT
GAAATCTTCAGCAAGCTGTCAAGCATGGACCGGCTCAAGATTAAAATGCCGGACAGCGTGCCGGCAAATGTCTCTGTATC
ATTCGGCACTTTATTTCCTTCGATTATTACCGTCACGATCATCGCCAGCTTCGGATTTGCGTTTCATCGGCTGACGGGGG
TATATCTTCATGAAGCCGTGTACAATGTCGTGCAAAAGCCGCTTGAGGGCGCGATTCAAGGTCTTCCCGGCATTCTCTTG
CTGGTGTTTGTCGCACAGTTTTTCTGGGTGATCGGCATACATGGAAACCAGATGGTGAAGCCGATCAGGGAGCCTTTGCT
GCTCGCTTCGATTACCGTCAATATGAATGCATACGCAGCCGGCGAATCGATTCCGAATATCATTACGATGCCGTTTTGGG
ATGTGTACATGAGCATCGGCGGATCCGGCGTCACAATCGGTCTGTTGATCGCGATGTTTATCGCGGGGAAACGGGAGGAT
TTGCGCAGCATTACAAAGATTTCGTTTGGTCCCGGCATCTTCAATATCAATGAACCGGTCATCTTTGGGGTTCCCGTCAT
GCTGAATCCGTTAATGGCGATTCCATTTATTGTGACGCCGCTTGTGACGGGTGCGATCGGTTACATCGCGACAGCGGCGG
GCTTTGCCGGAAAAGCCGTTGTCATGGTGCCGTGGACGACACCGCCGATTATCAATGCCTGGCTGTCAACAGGAGGAAGC
CTCGGTGCCGTCGTCACACAAATCGTATGCATCATCGTCTCCGTCCTTATTTATCTTCCGTTTGTTATTTTATTGAATCG
GACCTTTACGATTAGTTCTGAAAAAAATGTGTCTATGTAA

Upstream 100 bases:

>100_bases
ACCTGAAAAATTTCCTCTCCCAAAGGAAAAAATATGCACCGAAAAGAAAGCGTTTTCATTATAAAGTAAAAGCAAACCAC
CAAAAAAAGGGGGAGAGTAA

Downstream 100 bases:

>100_bases
AGCAAAGAAAGGTGTGAATGAGATGGCCAGACAAACGTGGAAGATTCCCGACGATTTTATTCTCGGCGCAGCAGCGTCGG
CGTGGCAGACAGAGGGGTGG

Product: hypothetical protein

Products: pyruvate; diacetylchitobiose-6-phosphate [Cytoplasm]; cellobiose-6-phosphate [Cytoplasm] [C]

Alternate protein names: EIIC-Lic; PTS system lichenan-specific EIIC component [H]

Number of amino acids: Translated: 439; Mature: 438

Protein sequence:

>439_residues
MSRMAKVTEMFERVAFKITSFKYIMVIKSAFVTLMPVIIAGAFAVLMQNMVMSPETGLAVFRPFRFLSALEPIMASINYA
TLNFITIGAVFLIGIELGKLNGHESFFPGLMALMSYISVIPSAVLLEVNGSMQEVVNVLAKEFTDPKSLFLGMFISIVSV
EIFSKLSSMDRLKIKMPDSVPANVSVSFGTLFPSIITVTIIASFGFAFHRLTGVYLHEAVYNVVQKPLEGAIQGLPGILL
LVFVAQFFWVIGIHGNQMVKPIREPLLLASITVNMNAYAAGESIPNIITMPFWDVYMSIGGSGVTIGLLIAMFIAGKRED
LRSITKISFGPGIFNINEPVIFGVPVMLNPLMAIPFIVTPLVTGAIGYIATAAGFAGKAVVMVPWTTPPIINAWLSTGGS
LGAVVTQIVCIIVSVLIYLPFVILLNRTFTISSEKNVSM

Sequences:

>Translated_439_residues
MSRMAKVTEMFERVAFKITSFKYIMVIKSAFVTLMPVIIAGAFAVLMQNMVMSPETGLAVFRPFRFLSALEPIMASINYA
TLNFITIGAVFLIGIELGKLNGHESFFPGLMALMSYISVIPSAVLLEVNGSMQEVVNVLAKEFTDPKSLFLGMFISIVSV
EIFSKLSSMDRLKIKMPDSVPANVSVSFGTLFPSIITVTIIASFGFAFHRLTGVYLHEAVYNVVQKPLEGAIQGLPGILL
LVFVAQFFWVIGIHGNQMVKPIREPLLLASITVNMNAYAAGESIPNIITMPFWDVYMSIGGSGVTIGLLIAMFIAGKRED
LRSITKISFGPGIFNINEPVIFGVPVMLNPLMAIPFIVTPLVTGAIGYIATAAGFAGKAVVMVPWTTPPIINAWLSTGGS
LGAVVTQIVCIIVSVLIYLPFVILLNRTFTISSEKNVSM
>Mature_438_residues
SRMAKVTEMFERVAFKITSFKYIMVIKSAFVTLMPVIIAGAFAVLMQNMVMSPETGLAVFRPFRFLSALEPIMASINYAT
LNFITIGAVFLIGIELGKLNGHESFFPGLMALMSYISVIPSAVLLEVNGSMQEVVNVLAKEFTDPKSLFLGMFISIVSVE
IFSKLSSMDRLKIKMPDSVPANVSVSFGTLFPSIITVTIIASFGFAFHRLTGVYLHEAVYNVVQKPLEGAIQGLPGILLL
VFVAQFFWVIGIHGNQMVKPIREPLLLASITVNMNAYAAGESIPNIITMPFWDVYMSIGGSGVTIGLLIAMFIAGKREDL
RSITKISFGPGIFNINEPVIFGVPVMLNPLMAIPFIVTPLVTGAIGYIATAAGFAGKAVVMVPWTTPPIINAWLSTGGSL
GAVVTQIVCIIVSVLIYLPFVILLNRTFTISSEKNVSM

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system i

COG id: COG1455

COG function: function code G; Phosphotransferase system cellobiose-specific component IIC

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-3 domain [H]

Homologues:

Organism=Escherichia coli, GI1788032, Length=447, Percent_Identity=29.9776286353468, Blast_Score=184, Evalue=1e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003352
- InterPro:   IPR004796
- InterPro:   IPR004501 [H]

Pfam domain/function: PF02378 PTS_EIIC [H]

EC number: NA

Molecular weight: Translated: 47576; Mature: 47445

Theoretical pI: Translated: 9.43; Mature: 9.43

Prosite motif: PS51105 PTS_EIIC_TYPE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHCCCEEECCCCCCCC
>Mature Secondary Structure 
SRMAKVTEMFERVAFKITSFKYIMVIKSAFVTLMPVIIAGAFAVLMQNMVMSPETGLAV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
FRPFRFLSALEPIMASINYATLNFITIGAVFLIGIELGKLNGHESFFPGLMALMSYISVI
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHC
PSAVLLEVNGSMQEVVNVLAKEFTDPKSLFLGMFISIVSVEIFSKLSSMDRLKIKMPDSV
CCCEEEEECCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCC
PANVSVSFGTLFPSIITVTIIASFGFAFHRLTGVYLHEAVYNVVQKPLEGAIQGLPGILL
CCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
LVFVAQFFWVIGIHGNQMVKPIREPLLLASITVNMNAYAAGESIPNIITMPFWDVYMSIG
HHHHHHHHHHHCCCCCHHHHHHHCCCEEEEEEECCCCEECCCCCCCEEECHHHHHHHHCC
GSGVTIGLLIAMFIAGKREDLRSITKISFGPGIFNINEPVIFGVPVMLNPLMAIPFIVTP
CCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEECCCCEEECCHHHHHHHHHHHHHHHH
LVTGAIGYIATAAGFAGKAVVMVPWTTPPIINAWLSTGGSLGAVVTQIVCIIVSVLIYLP
HHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
FVILLNRTFTISSEKNVSM
HHHHHCCCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: diacetylchitobiose [Periplasm]; phosphoenolpyruvate; cellobiose [Periplasm] [C]

Specific reaction: phosphoenolpyruvate + diacetylchitobiose [Periplasm] = pyruvate + diacetylchitobiose-6-phosphate [Cytoplasm] phosphoenolpyruvate + cellobiose [Periplasm] = cellobiose-6-phosphate [Cytoplasm] + pyruvate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8990303; 8969509; 9384377 [H]