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The map label for this gene is epiP [H]

Identifier: 52787801

GI number: 52787801

Start: 3942642

End: 3943973

Strand: Reverse

Name: epiP [H]

Synonym: BLi04124

Alternate gene names: 52787801

Gene position: 3943973-3942642 (Counterclockwise)

Preceding gene: 52787802

Following gene: 52787800

Centisome position: 93.4

GC content: 47.45

Gene sequence:

>1332_bases
GTGAAAAGAATATATATTTTTCTCTTATGTTTTGCAGTCCTGCTGCCGGTCGGCGGAAAGACGGCTCAAGCAAAAGAACA
AGCAGGAGAACAGTATCTTTTGCTTGAACATGTAAAAGATAAATCGAAACTGCTGGACACGGCGGAACAATTTCACATCC
ATGCCGATGTCATTGAAGAAATCGGATTTGCAAAAGTGACCGGTGAAAAACAAAAGCTTGCTCCTTTTACAAAGAAGCTT
GCTGAAAAAGTCGGGGCTGACGTCATTGAAAAGCCGATTGCAAATACAGCAGTAAACGAAACGGAATCAGTCATCAGCGG
TTCGCCTGCATGGGGGCTTGACGGTATTTTGGAACTAAAAGAATATCTATGGTTCGCTGCAAAGCAGACGGATTCCTATC
GCACGTATCAAATCGAAAGAGGGCATCCGGACGTCAAAGTTGCCTTGATTGACAGCGGACTGGATCTTGACCATCCGGAC
TTAAAAGCGTCCGTCAATACAAATGGCGGCTGGAATTACATTGACGGCAAGCCTGTATCCGGAGATCCGACAGGACACGG
AACACAAACAGCCGGGATGATCAATATCATTGCGCCAGATGTGACGATAACGCCTTATCAAGTGCTGGACGAAAAAGGCG
GAGACAGCTACAACATCATGAAGGCGATGGTTGATGCAGTCAATGACGGGCATGAAGTCATCAACATCAGTACGGGAAGC
TATACTTCTCTTGACAGGGAAGGAAAAGTGCTGATGAAAGCTTATCAAAGGGCTGCAAACTACGCTGCAAAGCATCAGGT
GCTGGTCTTCTCTTCCGCCGGCAATAAAGGAGTCAACCTTGATGAGATGAGGAAAACGGAAAACAAGGTGCATTTGCCGA
GCGCTTTGAAGCACGTCGTATCAGTCGGCAGCAATATGAAAAGCAACAATATTTCCCCATACTCCAATCAAGGGCGGGAA
ATTGAATTCACAGCCCCGGGAGGATATTTGGGAGAAACGTATGATCAGGATGGGATGGTTCGTGTGACAGACCTCGTACT
GACAACGTATCCGAAAGGGAAGGACAACACCGCATTAGACCAGATGCTAAACATCCCAAAGGGATATTCCCTCTCATACG
GAACAAGCTTGGCCGCCCCGCAGGTAGCTGGAACAGCTGCACTGGTTATATCTGAATACCGGGAGCGCCATCACAGGAAG
CCATCGGCTAAACAAGTGCATCACATCCTGAGGAAATCGGCATTAGACCTGGGCAAACCGGGGAAAGATGTTATATACGG
CTACGGGGAAGTACGCGCTTATCAAGCGCTGAAAATGATGAACAAGGAGTGA

Upstream 100 bases:

>100_bases
TAAATGTGGGTACGCATGAAACATTGCTGAATGAGAGCAAGTTTTACGGAGATTTTTATCGAAAGTTCCTTGAAAAAGAG
CAATCTGCAGAGGTGATGAT

Downstream 100 bases:

>100_bases
AGGGTATGTATGAATATCAAACAGTTTCAATCGCTGTAGGAGCATTCAACGGAAAACTTGAGAAAAATTATTCTGATGTG
ATTCATGAATATGCTGAAAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 443; Mature: 443

Protein sequence:

>443_residues
MKRIYIFLLCFAVLLPVGGKTAQAKEQAGEQYLLLEHVKDKSKLLDTAEQFHIHADVIEEIGFAKVTGEKQKLAPFTKKL
AEKVGADVIEKPIANTAVNETESVISGSPAWGLDGILELKEYLWFAAKQTDSYRTYQIERGHPDVKVALIDSGLDLDHPD
LKASVNTNGGWNYIDGKPVSGDPTGHGTQTAGMINIIAPDVTITPYQVLDEKGGDSYNIMKAMVDAVNDGHEVINISTGS
YTSLDREGKVLMKAYQRAANYAAKHQVLVFSSAGNKGVNLDEMRKTENKVHLPSALKHVVSVGSNMKSNNISPYSNQGRE
IEFTAPGGYLGETYDQDGMVRVTDLVLTTYPKGKDNTALDQMLNIPKGYSLSYGTSLAAPQVAGTAALVISEYRERHHRK
PSAKQVHHILRKSALDLGKPGKDVIYGYGEVRAYQALKMMNKE

Sequences:

>Translated_443_residues
MKRIYIFLLCFAVLLPVGGKTAQAKEQAGEQYLLLEHVKDKSKLLDTAEQFHIHADVIEEIGFAKVTGEKQKLAPFTKKL
AEKVGADVIEKPIANTAVNETESVISGSPAWGLDGILELKEYLWFAAKQTDSYRTYQIERGHPDVKVALIDSGLDLDHPD
LKASVNTNGGWNYIDGKPVSGDPTGHGTQTAGMINIIAPDVTITPYQVLDEKGGDSYNIMKAMVDAVNDGHEVINISTGS
YTSLDREGKVLMKAYQRAANYAAKHQVLVFSSAGNKGVNLDEMRKTENKVHLPSALKHVVSVGSNMKSNNISPYSNQGRE
IEFTAPGGYLGETYDQDGMVRVTDLVLTTYPKGKDNTALDQMLNIPKGYSLSYGTSLAAPQVAGTAALVISEYRERHHRK
PSAKQVHHILRKSALDLGKPGKDVIYGYGEVRAYQALKMMNKE
>Mature_443_residues
MKRIYIFLLCFAVLLPVGGKTAQAKEQAGEQYLLLEHVKDKSKLLDTAEQFHIHADVIEEIGFAKVTGEKQKLAPFTKKL
AEKVGADVIEKPIANTAVNETESVISGSPAWGLDGILELKEYLWFAAKQTDSYRTYQIERGHPDVKVALIDSGLDLDHPD
LKASVNTNGGWNYIDGKPVSGDPTGHGTQTAGMINIIAPDVTITPYQVLDEKGGDSYNIMKAMVDAVNDGHEVINISTGS
YTSLDREGKVLMKAYQRAANYAAKHQVLVFSSAGNKGVNLDEMRKTENKVHLPSALKHVVSVGSNMKSNNISPYSNQGRE
IEFTAPGGYLGETYDQDGMVRVTDLVLTTYPKGKDNTALDQMLNIPKGYSLSYGTSLAAPQVAGTAALVISEYRERHHRK
PSAKQVHHILRKSALDLGKPGKDVIYGYGEVRAYQALKMMNKE

Specific function: Protease which cleaves the matured lantibiotic from the modified prepeptide (Probable) [H]

COG id: COG1404

COG function: function code O; Subtilisin-like serine proteases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S8 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000209
- InterPro:   IPR022398
- InterPro:   IPR008357
- InterPro:   IPR015500 [H]

Pfam domain/function: PF00082 Peptidase_S8 [H]

EC number: NA

Molecular weight: Translated: 48510; Mature: 48510

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: PS00136 SUBTILASE_ASP ; PS00138 SUBTILASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRIYIFLLCFAVLLPVGGKTAQAKEQAGEQYLLLEHVKDKSKLLDTAEQFHIHADVIEE
CCHHHHHHHHHHHHHCCCCCCCHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGFAKVTGEKQKLAPFTKKLAEKVGADVIEKPIANTAVNETESVISGSPAWGLDGILELK
CCCEEECCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
EYLWFAAKQTDSYRTYQIERGHPDVKVALIDSGLDLDHPDLKASVNTNGGWNYIDGKPVS
HHHHHHHCCCCCEEEEEEECCCCCEEEEEEECCCCCCCCCCEEEECCCCCCCCCCCCCCC
GDPTGHGTQTAGMINIIAPDVTITPYQVLDEKGGDSYNIMKAMVDAVNDGHEVINISTGS
CCCCCCCCCCCCEEEEECCCCEECHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEEEECCC
YTSLDREGKVLMKAYQRAANYAAKHQVLVFSSAGNKGVNLDEMRKTENKVHLPSALKHVV
CCCCCCCCHHHHHHHHHHHHHHHHCEEEEEECCCCCCCCHHHHHHHCCCEECHHHHHHHH
SVGSNMKSNNISPYSNQGREIEFTAPGGYLGETYDQDGMVRVTDLVLTTYPKGKDNTALD
HHCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCHHHH
QMLNIPKGYSLSYGTSLAAPQVAGTAALVISEYRERHHRKPSAKQVHHILRKSALDLGKP
HHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCC
GKDVIYGYGEVRAYQALKMMNKE
CHHEEEECHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKRIYIFLLCFAVLLPVGGKTAQAKEQAGEQYLLLEHVKDKSKLLDTAEQFHIHADVIEE
CCHHHHHHHHHHHHHCCCCCCCHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGFAKVTGEKQKLAPFTKKLAEKVGADVIEKPIANTAVNETESVISGSPAWGLDGILELK
CCCEEECCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
EYLWFAAKQTDSYRTYQIERGHPDVKVALIDSGLDLDHPDLKASVNTNGGWNYIDGKPVS
HHHHHHHCCCCCEEEEEEECCCCCEEEEEEECCCCCCCCCCEEEECCCCCCCCCCCCCCC
GDPTGHGTQTAGMINIIAPDVTITPYQVLDEKGGDSYNIMKAMVDAVNDGHEVINISTGS
CCCCCCCCCCCCEEEEECCCCEECHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEEEECCC
YTSLDREGKVLMKAYQRAANYAAKHQVLVFSSAGNKGVNLDEMRKTENKVHLPSALKHVV
CCCCCCCCHHHHHHHHHHHHHHHHCEEEEEECCCCCCCCHHHHHHHCCCEECHHHHHHHH
SVGSNMKSNNISPYSNQGREIEFTAPGGYLGETYDQDGMVRVTDLVLTTYPKGKDNTALD
HHCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCHHHH
QMLNIPKGYSLSYGTSLAAPQVAGTAALVISEYRERHHRKPSAKQVHHILRKSALDLGKP
HHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCC
GKDVIYGYGEVRAYQALKMMNKE
CHHEEEECHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1740156 [H]