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The map label for this gene is katX [H]

Identifier: 52787788

GI number: 52787788

Start: 3933139

End: 3934737

Strand: Reverse

Name: katX [H]

Synonym: BLi04111

Alternate gene names: 52787788

Gene position: 3934737-3933139 (Counterclockwise)

Preceding gene: 52787789

Following gene: 52787786

Centisome position: 93.18

GC content: 49.66

Gene sequence:

>1599_bases
ATGGATCAGCATTCAAACGAGCAGAAATCTGACATGGAGACTGATGATACGTTAACAAACCGGCAGGGCCACCCGATCAC
AAACAATCAGAATATCAGAACCGTGGGCAACCGGGGGCCATCAACATTGGAGAACTATGATTTCCTGGAGAAGATCAGCC
ACTTTGACAGGGAGAGGGTTCCAGAGCGGGTCGTCCATGCCAGGGGAGCCGGAGCGCACGGCTATTTTGAAGCTTATGGG
ACAGCAGGCGATGAGCCGGTCTCAAAGTATACGAGAGCAAAGCTTTTTCAGGAAAAAGGCAAGAGAACCCCGGTGTTTGT
CCGTTTTTCGACGGTGACTCACGGGATATCCTCACCGGAAACGCTGCGGGATCCCCGCGGATTTGCGGTCAAGTTCTACA
CTGAAGACGGTAACTGGGATCTGGTCGGAAACAACTTGAAGATCTTCTTTATCCGCGATGCGGTAAAGTTTCCGGATTTA
ATCCATGCATTTAAGCCGGACCCGGTTACGAATTTGCAGGATGGCGAAAGAATCTTTGACTTCATTTCCAACACGCCTGA
AGCGATGCATATGATCACATTTTTGTTTTCGCCTTGGGGTATTCCGGCGAACTACCGGCAGATGCAGGGGTCCGGGGTGA
ACACGTACAAATGGGTGAATCAAGAAGGGGAAGCCGTGCTTGTGAAATATCACTGGGAACCGAAGCAGGGCATAAAAAAC
TTGACGCAAAAAGAGGCGGAAGAAATTCAGGCGAAGAATTTCAATCACGCCACACAGGATTTATATGAAGCGATTGAGCG
CGGAGATTATCCCGAGTGGGAGCTGTTCGTTCAAATCATGAGCGATGATGAGCATCCTGAGCTCGATTTTGACCCGCTTG
ACGACACGAAGCTGTGGCCTGAAGATCAATTTCCTTGGCTGCCTGTCGGCAAAATGGTTTTAAACAAAAATCCGGAAGAC
TACTTTACAGAAGTCGAACAAGCGGCATTTGGAACAGGGGTTCTTGTCGACGGACTTGACTTTTCCGATGACAAAATGCT
TCAGGGACGTACTTTTTCCTACTCGGATACACAGCGCTACAGAGTGGGAGCCAACTATCTGCAGCTGCCGATCAATGCGC
CGAAAAAAAGGGTGGCAACCAATCAGCGGGGCGGCCAGATGCAGTACAAGGTCGATTTAGGCAAAAATCAAAGCCCGCAC
ATCAACTATGAACCTTCAACCATCAACGGGCTGAAAGAAGCAAAGCAGGATGGCAAAGAATACACCCCGCATGTGGAAGG
AAACCTTGTGCGCGAAAGTATCGACAGGCAGAATAATTTCAAGCAGGCCGGGGACACTTACAGGCATTTCGAAGACTGGG
AAAAGGACGAGCTGATTACGAATCTGGTCAATACACTTGCCCCGTGCGACCAAAGAATTCAAACGAAGATGATCGATATG
CTGAAGCAATGCGACAAGGAATATGGAAGCAGAGTCGAGGAAGGATTAAAAAACGCCTCCAGCCAAAATACATCCAGCCG
GGAGCCGATCGGAGCAGAAGGCGCCGAAGATGCCCCGAGACAGGCGGAAGAAAAAGGGCACTCTCAAGACCCGTATTAA

Upstream 100 bases:

>100_bases
AAGAAAAATTTATTATCGTTGATTTGATCATGATAAATGCTGAATAACTTTTCTGGATTGGGATAAATTATTGTTAATTC
CAAATAAAGGGGGAAGAAGA

Downstream 100 bases:

>100_bases
AGAAGAAAACAGCGATGAACCTCTTGTGGGATTCATCGCTGTTTCACTTACGGAAGACCTTCGTCGGCTGAACGATATTT
GAGGATTTATCCCGTCTTCC

Product: KatX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 532; Mature: 532

Protein sequence:

>532_residues
MDQHSNEQKSDMETDDTLTNRQGHPITNNQNIRTVGNRGPSTLENYDFLEKISHFDRERVPERVVHARGAGAHGYFEAYG
TAGDEPVSKYTRAKLFQEKGKRTPVFVRFSTVTHGISSPETLRDPRGFAVKFYTEDGNWDLVGNNLKIFFIRDAVKFPDL
IHAFKPDPVTNLQDGERIFDFISNTPEAMHMITFLFSPWGIPANYRQMQGSGVNTYKWVNQEGEAVLVKYHWEPKQGIKN
LTQKEAEEIQAKNFNHATQDLYEAIERGDYPEWELFVQIMSDDEHPELDFDPLDDTKLWPEDQFPWLPVGKMVLNKNPED
YFTEVEQAAFGTGVLVDGLDFSDDKMLQGRTFSYSDTQRYRVGANYLQLPINAPKKRVATNQRGGQMQYKVDLGKNQSPH
INYEPSTINGLKEAKQDGKEYTPHVEGNLVRESIDRQNNFKQAGDTYRHFEDWEKDELITNLVNTLAPCDQRIQTKMIDM
LKQCDKEYGSRVEEGLKNASSQNTSSREPIGAEGAEDAPRQAEEKGHSQDPY

Sequences:

>Translated_532_residues
MDQHSNEQKSDMETDDTLTNRQGHPITNNQNIRTVGNRGPSTLENYDFLEKISHFDRERVPERVVHARGAGAHGYFEAYG
TAGDEPVSKYTRAKLFQEKGKRTPVFVRFSTVTHGISSPETLRDPRGFAVKFYTEDGNWDLVGNNLKIFFIRDAVKFPDL
IHAFKPDPVTNLQDGERIFDFISNTPEAMHMITFLFSPWGIPANYRQMQGSGVNTYKWVNQEGEAVLVKYHWEPKQGIKN
LTQKEAEEIQAKNFNHATQDLYEAIERGDYPEWELFVQIMSDDEHPELDFDPLDDTKLWPEDQFPWLPVGKMVLNKNPED
YFTEVEQAAFGTGVLVDGLDFSDDKMLQGRTFSYSDTQRYRVGANYLQLPINAPKKRVATNQRGGQMQYKVDLGKNQSPH
INYEPSTINGLKEAKQDGKEYTPHVEGNLVRESIDRQNNFKQAGDTYRHFEDWEKDELITNLVNTLAPCDQRIQTKMIDM
LKQCDKEYGSRVEEGLKNASSQNTSSREPIGAEGAEDAPRQAEEKGHSQDPY
>Mature_532_residues
MDQHSNEQKSDMETDDTLTNRQGHPITNNQNIRTVGNRGPSTLENYDFLEKISHFDRERVPERVVHARGAGAHGYFEAYG
TAGDEPVSKYTRAKLFQEKGKRTPVFVRFSTVTHGISSPETLRDPRGFAVKFYTEDGNWDLVGNNLKIFFIRDAVKFPDL
IHAFKPDPVTNLQDGERIFDFISNTPEAMHMITFLFSPWGIPANYRQMQGSGVNTYKWVNQEGEAVLVKYHWEPKQGIKN
LTQKEAEEIQAKNFNHATQDLYEAIERGDYPEWELFVQIMSDDEHPELDFDPLDDTKLWPEDQFPWLPVGKMVLNKNPED
YFTEVEQAAFGTGVLVDGLDFSDDKMLQGRTFSYSDTQRYRVGANYLQLPINAPKKRVATNQRGGQMQYKVDLGKNQSPH
INYEPSTINGLKEAKQDGKEYTPHVEGNLVRESIDRQNNFKQAGDTYRHFEDWEKDELITNLVNTLAPCDQRIQTKMIDM
LKQCDKEYGSRVEEGLKNASSQNTSSREPIGAEGAEDAPRQAEEKGHSQDPY

Specific function: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide [H]

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family [H]

Homologues:

Organism=Homo sapiens, GI4557014, Length=496, Percent_Identity=43.1451612903226, Blast_Score=417, Evalue=1e-116,
Organism=Escherichia coli, GI48994891, Length=445, Percent_Identity=45.3932584269663, Blast_Score=369, Evalue=1e-103,
Organism=Caenorhabditis elegans, GI71998444, Length=503, Percent_Identity=43.7375745526839, Blast_Score=431, Evalue=1e-121,
Organism=Caenorhabditis elegans, GI25147792, Length=500, Percent_Identity=42.8, Blast_Score=429, Evalue=1e-120,
Organism=Caenorhabditis elegans, GI25151141, Length=481, Percent_Identity=43.4511434511435, Blast_Score=428, Evalue=1e-120,
Organism=Saccharomyces cerevisiae, GI6320462, Length=521, Percent_Identity=38.9635316698656, Blast_Score=338, Evalue=2e-93,
Organism=Saccharomyces cerevisiae, GI6321525, Length=435, Percent_Identity=36.551724137931, Blast_Score=267, Evalue=3e-72,
Organism=Drosophila melanogaster, GI17981717, Length=489, Percent_Identity=42.7402862985685, Blast_Score=405, Evalue=1e-113,
Organism=Drosophila melanogaster, GI19920968, Length=502, Percent_Identity=39.4422310756972, Blast_Score=397, Evalue=1e-111,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002226
- InterPro:   IPR020835
- InterPro:   IPR010582
- InterPro:   IPR018028
- InterPro:   IPR011614 [H]

Pfam domain/function: PF00199 Catalase; PF06628 Catalase-rel [H]

EC number: =1.11.1.6 [H]

Molecular weight: Translated: 60997; Mature: 60997

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS00437 CATALASE_1 ; PS00438 CATALASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDQHSNEQKSDMETDDTLTNRQGHPITNNQNIRTVGNRGPSTLENYDFLEKISHFDRERV
CCCCCCCHHHCCCCCHHHCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHH
PERVVHARGAGAHGYFEAYGTAGDEPVSKYTRAKLFQEKGKRTPVFVRFSTVTHGISSPE
HHHHHHHCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEHHHCCCCCCH
TLRDPRGFAVKFYTEDGNWDLVGNNLKIFFIRDAVKFPDLIHAFKPDPVTNLQDGERIFD
HHCCCCCCEEEEEEECCCEEEECCCEEEEEEECCHHCHHHHHHCCCCCCCCCCCHHHHHH
FISNTPEAMHMITFLFSPWGIPANYRQMQGSGVNTYKWVNQEGEAVLVKYHWEPKQGIKN
HHHCCHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCEEEECCCCCEEEEEEECCHHHHHHH
LTQKEAEEIQAKNFNHATQDLYEAIERGDYPEWELFVQIMSDDEHPELDFDPLDDTKLWP
HHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCC
EDQFPWLPVGKMVLNKNPEDYFTEVEQAAFGTGVLVDGLDFSDDKMLQGRTFSYSDTQRY
CCCCCCCCCCHHHHCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCCE
RVGANYLQLPINAPKKRVATNQRGGQMQYKVDLGKNQSPHINYEPSTINGLKEAKQDGKE
EECCCEEEECCCCCHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCC
YTPHVEGNLVRESIDRQNNFKQAGDTYRHFEDWEKDELITNLVNTLAPCDQRIQTKMIDM
CCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LKQCDKEYGSRVEEGLKNASSQNTSSREPIGAEGAEDAPRQAEEKGHSQDPY
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCC
>Mature Secondary Structure
MDQHSNEQKSDMETDDTLTNRQGHPITNNQNIRTVGNRGPSTLENYDFLEKISHFDRERV
CCCCCCCHHHCCCCCHHHCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHH
PERVVHARGAGAHGYFEAYGTAGDEPVSKYTRAKLFQEKGKRTPVFVRFSTVTHGISSPE
HHHHHHHCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEHHHCCCCCCH
TLRDPRGFAVKFYTEDGNWDLVGNNLKIFFIRDAVKFPDLIHAFKPDPVTNLQDGERIFD
HHCCCCCCEEEEEEECCCEEEECCCEEEEEEECCHHCHHHHHHCCCCCCCCCCCHHHHHH
FISNTPEAMHMITFLFSPWGIPANYRQMQGSGVNTYKWVNQEGEAVLVKYHWEPKQGIKN
HHHCCHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCEEEECCCCCEEEEEEECCHHHHHHH
LTQKEAEEIQAKNFNHATQDLYEAIERGDYPEWELFVQIMSDDEHPELDFDPLDDTKLWP
HHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCC
EDQFPWLPVGKMVLNKNPEDYFTEVEQAAFGTGVLVDGLDFSDDKMLQGRTFSYSDTQRY
CCCCCCCCCCHHHHCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCCE
RVGANYLQLPINAPKKRVATNQRGGQMQYKVDLGKNQSPHINYEPSTINGLKEAKQDGKE
EECCCEEEECCCCCHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCC
YTPHVEGNLVRESIDRQNNFKQAGDTYRHFEDWEKDELITNLVNTLAPCDQRIQTKMIDM
CCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LKQCDKEYGSRVEEGLKNASSQNTSSREPIGAEGAEDAPRQAEEKGHSQDPY
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969509; 9384377 [H]