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The map label for this gene is yvyH [H]

Identifier: 52787492

GI number: 52787492

Start: 3631995

End: 3633137

Strand: Reverse

Name: yvyH [H]

Synonym: BLi03812

Alternate gene names: 52787492

Gene position: 3633137-3631995 (Counterclockwise)

Preceding gene: 52787494

Following gene: 52787490

Centisome position: 86.04

GC content: 49.78

Gene sequence:

>1143_bases
ATGAAGAAACTAAAAGTCATGACAGTATTCGGCACGCGCCCTGAAGCCATAAAAATGGCTCCGCTCGTGCTAGAATTAAG
AAAATATCCCGAAATTGAGTCTTATGTGACGGTTACAGCCCAGCACAGGCAAATGCTTGACCAGGTGCTTGAAGCTTTTA
ACATAAAGCCTGATTTTGATTTGAATATCATGAAAGAAAGGCAAACGCTGGCTGAAATTACGTCTAATGCGCTTGTGAAG
CTGGACGAGCTGTTTCAGTCTATCAAACCGGATATTGTGCTTGTCCACGGTGATACGACAACGACATTTGCGGGGAGTCT
TGCCGCTTATTATCACCAGATTTCCGTCGGCCATGTAGAGGCGGGGCTCAGGACCGGAAACAAATACTCGCCGTTTCCAG
AAGAGCTGAACAGGCAGCTGACGGGATCGATTGCCGATCTTCATTTTGCGCCGACAGAGCAGGCCGAACAGAATCTGCTC
CGCGAAAATAAAGATCCTGAGACGATTTTCATCACTGGAAATACTGCAATCGATGCACTTCGCACAACAGTAAGGGACGG
CTATTCACACCCCGTTCTTGAAAAAATCGGAAATGATAAGATGATCTTGCTTACCGCCCACCGCCGGGAAAATTTAGGGA
AGCCGATGGAAAACATGTTTAAAGCGATCAGGCGGATCGTCGAAGAGTTCGACGGCGTCCAGGTCGTTTATCCCGTTCAT
CTCAATCCCGCTGTTCGTGAAGCGGCTGCAAAGCATTTCGGCGATTTGAATAAAGTCCACCTGATAGAGCCGCTCGAAGT
CATCGATTTTCACAACTTTGCAGCTGAAGCTCACTTCATCCTCACCGACTCTGGAGGGGTGCAGGAAGAAGCGCCGTCGC
TAGGAAAGCCGGTCCTCGTGCTTCGCGATACGACGGAACGGCCCGAAGGCGTCCAGGCCGGGACGCTTAAACTGGCAGGC
ACGGATGAAGATAAGATTTACCAGCTGACTAAACAGCTGTTGACCGATCAAGATGAATATCGAAAAATGTCCAGGGCTTC
AAACCCGTACGGGGACGGACAGGCTTCGCGGCGAATTGCGGAGGCGCTGCTTTATCGGTACGGATACCGAAGCGCGCGGC
CTGATGTGTTTAAAGATAAATAA

Upstream 100 bases:

>100_bases
GGATTAATTCCAACGAGAAAACACGGGCAAAGCGGTAATCAATCGATTCAGCAGACGATTCTTAAAAAAGCTGTTCATAC
AGAAAACAGGTGATAGAAAA

Downstream 100 bases:

>100_bases
AAAAGCTTCCTTTTCAGGAAGCTTTCAGCGGTGTCGACAAACCCTCGCATTCGTTGTCAGGCCTGCGCGTCGGTGCTCAC
GAATTCCAACATTCGCTGCG

Product: YvyH

Products: NA

Alternate protein names: UDP-GlcNAc-2-epimerase [H]

Number of amino acids: Translated: 380; Mature: 380

Protein sequence:

>380_residues
MKKLKVMTVFGTRPEAIKMAPLVLELRKYPEIESYVTVTAQHRQMLDQVLEAFNIKPDFDLNIMKERQTLAEITSNALVK
LDELFQSIKPDIVLVHGDTTTTFAGSLAAYYHQISVGHVEAGLRTGNKYSPFPEELNRQLTGSIADLHFAPTEQAEQNLL
RENKDPETIFITGNTAIDALRTTVRDGYSHPVLEKIGNDKMILLTAHRRENLGKPMENMFKAIRRIVEEFDGVQVVYPVH
LNPAVREAAAKHFGDLNKVHLIEPLEVIDFHNFAAEAHFILTDSGGVQEEAPSLGKPVLVLRDTTERPEGVQAGTLKLAG
TDEDKIYQLTKQLLTDQDEYRKMSRASNPYGDGQASRRIAEALLYRYGYRSARPDVFKDK

Sequences:

>Translated_380_residues
MKKLKVMTVFGTRPEAIKMAPLVLELRKYPEIESYVTVTAQHRQMLDQVLEAFNIKPDFDLNIMKERQTLAEITSNALVK
LDELFQSIKPDIVLVHGDTTTTFAGSLAAYYHQISVGHVEAGLRTGNKYSPFPEELNRQLTGSIADLHFAPTEQAEQNLL
RENKDPETIFITGNTAIDALRTTVRDGYSHPVLEKIGNDKMILLTAHRRENLGKPMENMFKAIRRIVEEFDGVQVVYPVH
LNPAVREAAAKHFGDLNKVHLIEPLEVIDFHNFAAEAHFILTDSGGVQEEAPSLGKPVLVLRDTTERPEGVQAGTLKLAG
TDEDKIYQLTKQLLTDQDEYRKMSRASNPYGDGQASRRIAEALLYRYGYRSARPDVFKDK
>Mature_380_residues
MKKLKVMTVFGTRPEAIKMAPLVLELRKYPEIESYVTVTAQHRQMLDQVLEAFNIKPDFDLNIMKERQTLAEITSNALVK
LDELFQSIKPDIVLVHGDTTTTFAGSLAAYYHQISVGHVEAGLRTGNKYSPFPEELNRQLTGSIADLHFAPTEQAEQNLL
RENKDPETIFITGNTAIDALRTTVRDGYSHPVLEKIGNDKMILLTAHRRENLGKPMENMFKAIRRIVEEFDGVQVVYPVH
LNPAVREAAAKHFGDLNKVHLIEPLEVIDFHNFAAEAHFILTDSGGVQEEAPSLGKPVLVLRDTTERPEGVQAGTLKLAG
TDEDKIYQLTKQLLTDQDEYRKMSRASNPYGDGQASRRIAEALLYRYGYRSARPDVFKDK

Specific function: Catalyzes the conversion of UDP-N-acetylglucosamine into UDP-N-acetylmannosamine, a precursor of the teichoic acid linkage unit [H]

COG id: COG0381

COG function: function code M; UDP-N-acetylglucosamine 2-epimerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-N-acetylglucosamine 2-epimerase family [H]

Homologues:

Organism=Homo sapiens, GI190014632, Length=383, Percent_Identity=24.0208877284595, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI4885285, Length=383, Percent_Identity=24.0208877284595, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI298566312, Length=383, Percent_Identity=24.0208877284595, Blast_Score=72, Evalue=9e-13,
Organism=Escherichia coli, GI48994967, Length=372, Percent_Identity=57.258064516129, Blast_Score=389, Evalue=1e-109,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003331 [H]

Pfam domain/function: PF02350 Epimerase_2 [H]

EC number: =5.1.3.14 [H]

Molecular weight: Translated: 42843; Mature: 42843

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLKVMTVFGTRPEAIKMAPLVLELRKYPEIESYVTVTAQHRQMLDQVLEAFNIKPDFD
CCCEEEEEEECCCCCHHHHHHHHHHHHCCCCCHHHEEEHHHHHHHHHHHHHHHCCCCCCC
LNIMKERQTLAEITSNALVKLDELFQSIKPDIVLVHGDTTTTFAGSLAAYYHQISVGHVE
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHH
AGLRTGNKYSPFPEELNRQLTGSIADLHFAPTEQAEQNLLRENKDPETIFITGNTAIDAL
HHHCCCCCCCCCHHHHHHHHCCCHHHEECCCCHHHHHHHHHCCCCCCEEEEECCHHHHHH
RTTVRDGYSHPVLEKIGNDKMILLTAHRRENLGKPMENMFKAIRRIVEEFDGVQVVYPVH
HHHHHCCCCCHHHHHCCCCCEEEEEECHHHCCCCHHHHHHHHHHHHHHHCCCCEEEEEEE
LNPAVREAAAKHFGDLNKVHLIEPLEVIDFHNFAAEAHFILTDSGGVQEEAPSLGKPVLV
CCHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCEEE
LRDTTERPEGVQAGTLKLAGTDEDKIYQLTKQLLTDQDEYRKMSRASNPYGDGQASRRIA
EECCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHH
EALLYRYGYRSARPDVFKDK
HHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MKKLKVMTVFGTRPEAIKMAPLVLELRKYPEIESYVTVTAQHRQMLDQVLEAFNIKPDFD
CCCEEEEEEECCCCCHHHHHHHHHHHHCCCCCHHHEEEHHHHHHHHHHHHHHHCCCCCCC
LNIMKERQTLAEITSNALVKLDELFQSIKPDIVLVHGDTTTTFAGSLAAYYHQISVGHVE
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHH
AGLRTGNKYSPFPEELNRQLTGSIADLHFAPTEQAEQNLLRENKDPETIFITGNTAIDAL
HHHCCCCCCCCCHHHHHHHHCCCHHHEECCCCHHHHHHHHHCCCCCCEEEEECCHHHHHH
RTTVRDGYSHPVLEKIGNDKMILLTAHRRENLGKPMENMFKAIRRIVEEFDGVQVVYPVH
HHHHHCCCCCHHHHHCCCCCEEEEEECHHHCCCCHHHHHHHHHHHHHHHCCCCEEEEEEE
LNPAVREAAAKHFGDLNKVHLIEPLEVIDFHNFAAEAHFILTDSGGVQEEAPSLGKPVLV
CCHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCEEE
LRDTTERPEGVQAGTLKLAGTDEDKIYQLTKQLLTDQDEYRKMSRASNPYGDGQASRRIA
EECCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHH
EALLYRYGYRSARPDVFKDK
HHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8126437; 12107153; 9384377 [H]