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The map label for this gene is galE [C]

Identifier: 52787483

GI number: 52787483

Start: 3620540

End: 3621469

Strand: Reverse

Name: galE [C]

Synonym: BLi03803

Alternate gene names: 52787483

Gene position: 3621469-3620540 (Counterclockwise)

Preceding gene: 52787484

Following gene: 52787482

Centisome position: 85.76

GC content: 43.55

Gene sequence:

>930_bases
ATGGAAAAAGTACTAGTGACAGGCGGATGCGGATTTATCGGCTCGCATATTGCTGAACAGCTTCTAAAAGAAAATTACCG
GGTTTCAATTCTTGATAATTTAACTACGGGACACCGCTCCAACATTGACGGTCTCCCAATTGACTTTTATGAGCAGGATA
TCACGAAGCCGGAAGTCATCGACGTCATCAAAAGCATTGATCCCGATTATATTGTTCATTTAGCTGCACAAGTAAGCGTA
GCGGAGTCTGTCAGCGATTTTTTAAATGATGAAAACATCAATATCAGAGGATCGCTCCATATCATTAAAGCAGCTGGTGA
ATGCAATGTGAAAAAGATCGTCTTTGCATCATCAGCGGCTGTTTATGGAAATCCGGATTACCTGCCTGTCGACACCCGTC
ACCAAACAAACCCAGGCTCACCCTACGGGCTGACGAAGCTTACAGTGGAGAACTATTTAAAACTGGCTTATGATCTATAT
GGAACCGAGTATTGCATTTTGCGGTACAGCAACGTGTACGGGCCGCGCCAGGATGCAAAAGGAGAGGGCGGCGTTGTATC
GATTTTCTCCGATTTGCTGACCAGCGGCAAGGCTCCGGTAATTTTTGGAGACGGAGAACAATCACGCGATTTTATTTATG
TCGGTGATGTAGCTTGTGCCAACGTAAAGGCGCTAAAAGCTCAATCAAACGTTTGTTTAAATGTTTCAAACGGCTTTTCC
ATCACGGTCAATGAGCTGTTTACAGAGATGAAAAAAGCGACGAACTCTGAGCTTTCTCCGATTTATCAAGATGAACGGCC
GGGGGATATCCGCCACAGCACACTGTGTAATGAAGAAACAAAGAAAATCTTAAACTGGGAACCAAAAATGCCGCTTGCTG
AAGGACTGGAAAAGACCATTTCATATTATAAAAAAGAAATGAATACGTAA

Upstream 100 bases:

>100_bases
AACAAATGAGAAACGAAGGCATGATCTACCATTCAATCGGACGGCCGGAAGTACAGGGAGAAGGAATCCTGACCAACGTA
TAAACAACGGGGGGATAACA

Downstream 100 bases:

>100_bases
ATCACTGGCTGCTGGCTGATGTCGGCAGCCCTTTTCCAGAAAGAAGCGGAAGGAGGGGGAAAAATGAGTCTCAAACGTTC
CGCGGTCAATGTTCTGGTTT

Product: hypothetical protein

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MEKVLVTGGCGFIGSHIAEQLLKENYRVSILDNLTTGHRSNIDGLPIDFYEQDITKPEVIDVIKSIDPDYIVHLAAQVSV
AESVSDFLNDENINIRGSLHIIKAAGECNVKKIVFASSAAVYGNPDYLPVDTRHQTNPGSPYGLTKLTVENYLKLAYDLY
GTEYCILRYSNVYGPRQDAKGEGGVVSIFSDLLTSGKAPVIFGDGEQSRDFIYVGDVACANVKALKAQSNVCLNVSNGFS
ITVNELFTEMKKATNSELSPIYQDERPGDIRHSTLCNEETKKILNWEPKMPLAEGLEKTISYYKKEMNT

Sequences:

>Translated_309_residues
MEKVLVTGGCGFIGSHIAEQLLKENYRVSILDNLTTGHRSNIDGLPIDFYEQDITKPEVIDVIKSIDPDYIVHLAAQVSV
AESVSDFLNDENINIRGSLHIIKAAGECNVKKIVFASSAAVYGNPDYLPVDTRHQTNPGSPYGLTKLTVENYLKLAYDLY
GTEYCILRYSNVYGPRQDAKGEGGVVSIFSDLLTSGKAPVIFGDGEQSRDFIYVGDVACANVKALKAQSNVCLNVSNGFS
ITVNELFTEMKKATNSELSPIYQDERPGDIRHSTLCNEETKKILNWEPKMPLAEGLEKTISYYKKEMNT
>Mature_309_residues
MEKVLVTGGCGFIGSHIAEQLLKENYRVSILDNLTTGHRSNIDGLPIDFYEQDITKPEVIDVIKSIDPDYIVHLAAQVSV
AESVSDFLNDENINIRGSLHIIKAAGECNVKKIVFASSAAVYGNPDYLPVDTRHQTNPGSPYGLTKLTVENYLKLAYDLY
GTEYCILRYSNVYGPRQDAKGEGGVVSIFSDLLTSGKAPVIFGDGEQSRDFIYVGDVACANVKALKAQSNVCLNVSNGFS
ITVNELFTEMKKATNSELSPIYQDERPGDIRHSTLCNEETKKILNWEPKMPLAEGLEKTISYYKKEMNT

Specific function: Galactose metabolism; third step. [C]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI7657641, Length=326, Percent_Identity=30.3680981595092, Blast_Score=128, Evalue=7e-30,
Organism=Homo sapiens, GI42516563, Length=315, Percent_Identity=28.2539682539683, Blast_Score=128, Evalue=7e-30,
Organism=Homo sapiens, GI56237023, Length=337, Percent_Identity=27.893175074184, Blast_Score=118, Evalue=6e-27,
Organism=Homo sapiens, GI56118217, Length=337, Percent_Identity=27.893175074184, Blast_Score=118, Evalue=6e-27,
Organism=Homo sapiens, GI189083684, Length=337, Percent_Identity=27.893175074184, Blast_Score=118, Evalue=6e-27,
Organism=Escherichia coli, GI1786974, Length=334, Percent_Identity=29.940119760479, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1788353, Length=337, Percent_Identity=27.5964391691395, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1790049, Length=243, Percent_Identity=30.0411522633745, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI48994969, Length=346, Percent_Identity=26.5895953757225, Blast_Score=80, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71982035, Length=341, Percent_Identity=30.2052785923754, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI71982038, Length=343, Percent_Identity=30.0291545189504, Blast_Score=115, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17539532, Length=326, Percent_Identity=26.6871165644172, Blast_Score=111, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI17568069, Length=325, Percent_Identity=29.8461538461538, Blast_Score=107, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI115532424, Length=340, Percent_Identity=25.5882352941176, Blast_Score=82, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6319493, Length=325, Percent_Identity=29.8461538461538, Blast_Score=114, Evalue=2e-26,
Organism=Drosophila melanogaster, GI19923002, Length=343, Percent_Identity=30.3206997084548, Blast_Score=123, Evalue=1e-28,
Organism=Drosophila melanogaster, GI21356223, Length=317, Percent_Identity=28.391167192429, Blast_Score=122, Evalue=4e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 34151; Mature: 34151

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKVLVTGGCGFIGSHIAEQLLKENYRVSILDNLTTGHRSNIDGLPIDFYEQDITKPEVI
CCEEEEECCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCHHHHCCCCHHHH
DVIKSIDPDYIVHLAAQVSVAESVSDFLNDENINIRGSLHIIKAAGECNVKKIVFASSAA
HHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEECCCCCEEEEEEECCEE
VYGNPDYLPVDTRHQTNPGSPYGLTKLTVENYLKLAYDLYGTEYCILRYSNVYGPRQDAK
ECCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCC
GEGGVVSIFSDLLTSGKAPVIFGDGEQSRDFIYVGDVACANVKALKAQSNVCLNVSNGFS
CCCCHHHHHHHHHHCCCCCEEECCCCCCCCEEEECCEECCCHHEEECCCCEEEEECCCCE
ITVNELFTEMKKATNSELSPIYQDERPGDIRHSTLCNEETKKILNWEPKMPLAEGLEKTI
EEHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHCCCCCCCHHHHHHHHH
SYYKKEMNT
HHHHHHCCC
>Mature Secondary Structure
MEKVLVTGGCGFIGSHIAEQLLKENYRVSILDNLTTGHRSNIDGLPIDFYEQDITKPEVI
CCEEEEECCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCHHHHCCCCHHHH
DVIKSIDPDYIVHLAAQVSVAESVSDFLNDENINIRGSLHIIKAAGECNVKKIVFASSAA
HHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEECCCCCEEEEEEECCEE
VYGNPDYLPVDTRHQTNPGSPYGLTKLTVENYLKLAYDLYGTEYCILRYSNVYGPRQDAK
ECCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCC
GEGGVVSIFSDLLTSGKAPVIFGDGEQSRDFIYVGDVACANVKALKAQSNVCLNVSNGFS
CCCCHHHHHHHHHHCCCCCEEECCCCCCCCEEEECCEECCCHHEEECCCCEEEEECCCCE
ITVNELFTEMKKATNSELSPIYQDERPGDIRHSTLCNEETKKILNWEPKMPLAEGLEKTI
EEHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHCCCCCCCHHHHHHHHH
SYYKKEMNT
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]