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The map label for this gene is comFA [H]

Identifier: 52787471

GI number: 52787471

Start: 3608187

End: 3609581

Strand: Reverse

Name: comFA [H]

Synonym: BLi03791

Alternate gene names: 52787471

Gene position: 3609581-3608187 (Counterclockwise)

Preceding gene: 52787472

Following gene: 52787470

Centisome position: 85.48

GC content: 47.96

Gene sequence:

>1395_bases
GTGATTCACATCGAACAACCGGCATTCTATACCCGTGAATTGCGGTCATGTTTGGAGCAGCGCCACCTTCTGAAAAGCGA
ACTTCCTTTTCGTGAATCCGTCGTTGATTGGCATATCCAAGAAGGCTTGATAAAAACGGAGGAAGGTATTAAAAAAACGA
AGAAAGGCTTTATTTGTTTGAGGTGCGGCCAGCACGAACGCTCATTTTTCGCCCGGTATCCTTGCTATCGGTGCAGTAAA
TGCTGCGTGTACTGCCGATCCTGCGTCATGATGGGCAGGGTGAGCGATTGTACGCCTCTGTTGACTTGGCACATGCATGT
CAGCCATAAATGGGCGCCTGTTCATACGGAGTGGAAAGGCGCGCTTTCAGCAGGTCAGGAGAAAGCGGCCAAATCCATTA
TCAATGCTATACGAAGAAAAGAAGAACTGTTGGTCTGGGCGGTTTGCGGGTCGGGGAAAACAGAACTTCTCTTTCAAGGG
ATCGAATTCGCGCTGAACAACGGCTTGACAGTATGTATCGCTACTCCGAGAACCGATGTCGTACTCGAGCTTGCTCCGCG
GTTTCGCCAAGCCTTTCCAGGGGTGGAAATTGCCGCTTTGTACGGAGGAAGCTCAGACGTTGGGAATCTCTCGCCGCTTA
TCATTTCAACTACCCACCAGCTGCTCCGCTATAAAGAAGCATTTGACGTGATCATCATAGATGAGGTGGATGCTTTTCCG
TATTCTATTGATAACACGCTGCAATACGCTGTTAAAAAATCGGCAAAACGGCAAAGCGCTCACATCTATTTAACTGCCAC
GCCTTCAGCAGATATGAAAAAAAGGGCTGAGAGCGGAAAGCTGGACACCGTCCGTATTCCCGCGAGATTCCACCGCAGCC
CCTTGCCTGAACCTACATTGATTTGGTGCGGAAATTGGAAAAAGAGTTTGAAACGAAGAAAAGTTCCTTTTCGCCTCAAA
AAATGGCTTTTTAAGCACCAAGAACTGCAGCAACCGGTTTTTTTATTCGTTCCCTCTGTCCCTGTTCTTAAATCTGTGGT
CAGTGTGCTGAAAAAGGAAACATTTCGCGCTGAAGGAGTTTATGCCGATGACCCTGACAGAAATGAAAAAGTGAACCGGT
TTAGGGAAAGTAAGCTTGAGGTGCTCGTGACAACAACGATTTTGGAAAGAGGAGTGACCGTCAAAAAAGCGCAGGTTGGA
GTATTGGGGGCAGAGTCGGCGGTTTTTACCGAAAGCGCCCTCGTCCAAATGGCGGGAAGAGCCGGCAGGCATCCCGAGCA
CACAGATGGAGACGTCTGTTTCTTTCATTACGGCAGGACAAAGTCGATGAATGCGGCACGACGTCATATTCAAAACATGA
ATAAAATGTCTAAAAAGGAAATGTTGATTGACTAG

Upstream 100 bases:

>100_bases
AAACGGAGATTTTTTTTTCAACTGTTTTGAAGGGAGATTTTTAGATTTTGACTGTTTTACAAGAAACCATGGATGATAGA
TACTAAATGGCAGATTGGAG

Downstream 100 bases:

>100_bases
TCTGATATTCATGGTAAAGTATACCTATGAATATAAAATGAGGAGCGGTGCCGGATGCTAGTCAACGCCAAAGAAGCTGT
TTTGGAAGAGTTGTTTGATC

Product: ComFA

Products: NA

Alternate protein names: ATP-dependent helicase ComFA [H]

Number of amino acids: Translated: 464; Mature: 464

Protein sequence:

>464_residues
MIHIEQPAFYTRELRSCLEQRHLLKSELPFRESVVDWHIQEGLIKTEEGIKKTKKGFICLRCGQHERSFFARYPCYRCSK
CCVYCRSCVMMGRVSDCTPLLTWHMHVSHKWAPVHTEWKGALSAGQEKAAKSIINAIRRKEELLVWAVCGSGKTELLFQG
IEFALNNGLTVCIATPRTDVVLELAPRFRQAFPGVEIAALYGGSSDVGNLSPLIISTTHQLLRYKEAFDVIIIDEVDAFP
YSIDNTLQYAVKKSAKRQSAHIYLTATPSADMKKRAESGKLDTVRIPARFHRSPLPEPTLIWCGNWKKSLKRRKVPFRLK
KWLFKHQELQQPVFLFVPSVPVLKSVVSVLKKETFRAEGVYADDPDRNEKVNRFRESKLEVLVTTTILERGVTVKKAQVG
VLGAESAVFTESALVQMAGRAGRHPEHTDGDVCFFHYGRTKSMNAARRHIQNMNKMSKKEMLID

Sequences:

>Translated_464_residues
MIHIEQPAFYTRELRSCLEQRHLLKSELPFRESVVDWHIQEGLIKTEEGIKKTKKGFICLRCGQHERSFFARYPCYRCSK
CCVYCRSCVMMGRVSDCTPLLTWHMHVSHKWAPVHTEWKGALSAGQEKAAKSIINAIRRKEELLVWAVCGSGKTELLFQG
IEFALNNGLTVCIATPRTDVVLELAPRFRQAFPGVEIAALYGGSSDVGNLSPLIISTTHQLLRYKEAFDVIIIDEVDAFP
YSIDNTLQYAVKKSAKRQSAHIYLTATPSADMKKRAESGKLDTVRIPARFHRSPLPEPTLIWCGNWKKSLKRRKVPFRLK
KWLFKHQELQQPVFLFVPSVPVLKSVVSVLKKETFRAEGVYADDPDRNEKVNRFRESKLEVLVTTTILERGVTVKKAQVG
VLGAESAVFTESALVQMAGRAGRHPEHTDGDVCFFHYGRTKSMNAARRHIQNMNKMSKKEMLID
>Mature_464_residues
MIHIEQPAFYTRELRSCLEQRHLLKSELPFRESVVDWHIQEGLIKTEEGIKKTKKGFICLRCGQHERSFFARYPCYRCSK
CCVYCRSCVMMGRVSDCTPLLTWHMHVSHKWAPVHTEWKGALSAGQEKAAKSIINAIRRKEELLVWAVCGSGKTELLFQG
IEFALNNGLTVCIATPRTDVVLELAPRFRQAFPGVEIAALYGGSSDVGNLSPLIISTTHQLLRYKEAFDVIIIDEVDAFP
YSIDNTLQYAVKKSAKRQSAHIYLTATPSADMKKRAESGKLDTVRIPARFHRSPLPEPTLIWCGNWKKSLKRRKVPFRLK
KWLFKHQELQQPVFLFVPSVPVLKSVVSVLKKETFRAEGVYADDPDRNEKVNRFRESKLEVLVTTTILERGVTVKKAQVG
VLGAESAVFTESALVQMAGRAGRHPEHTDGDVCFFHYGRTKSMNAARRHIQNMNKMSKKEMLID

Specific function: Involved in transformation (competence for DNA uptake). Required for DNA uptake but not for binding. May provide the driving force for transport of DNA through an aqueous channel [H]

COG id: COG4098

COG function: function code L; Superfamily II DNA/RNA helicase required for DNA uptake (late competence protein)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR006935 [H]

Pfam domain/function: PF00271 Helicase_C; PF04851 ResIII [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 52849; Mature: 52849

Theoretical pI: Translated: 9.96; Mature: 9.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIHIEQPAFYTRELRSCLEQRHLLKSELPFRESVVDWHIQEGLIKTEEGIKKTKKGFICL
CEEECCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCEEEE
RCGQHERSFFARYPCYRCSKCCVYCRSCVMMGRVSDCTPLLTWHMHVSHKWAPVHTEWKG
ECCCCHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCCCCHHH
ALSAGQEKAAKSIINAIRRKEELLVWAVCGSGKTELLFQGIEFALNNGLTVCIATPRTDV
HHHCCHHHHHHHHHHHHHHHHHEEEEEEECCCCHHHHHHHHHHHHCCCCEEEEECCCCCH
VLELAPRFRQAFPGVEIAALYGGSSDVGNLSPLIISTTHQLLRYKEAFDVIIIDEVDAFP
HHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCEEHHHHHHHHHHHHCCEEEEECCCCCC
YSIDNTLQYAVKKSAKRQSAHIYLTATPSADMKKRAESGKLDTVRIPARFHRSPLPEPTL
CCHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHCCCCCEEECCHHHCCCCCCCCCE
IWCGNWKKSLKRRKVPFRLKKWLFKHQELQQPVFLFVPSVPVLKSVVSVLKKETFRAEGV
EEECCHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHCCCC
YADDPDRNEKVNRFRESKLEVLVTTTILERGVTVKKAQVGVLGAESAVFTESALVQMAGR
CCCCCCCHHHHHHHHHHHHHEEEEHHHHHCCCEEEEEEEEEEECCHHHHHHHHHHHHHHH
AGRHPEHTDGDVCFFHYGRTKSMNAARRHIQNMNKMSKKEMLID
CCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIHIEQPAFYTRELRSCLEQRHLLKSELPFRESVVDWHIQEGLIKTEEGIKKTKKGFICL
CEEECCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCEEEE
RCGQHERSFFARYPCYRCSKCCVYCRSCVMMGRVSDCTPLLTWHMHVSHKWAPVHTEWKG
ECCCCHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCCCCHHH
ALSAGQEKAAKSIINAIRRKEELLVWAVCGSGKTELLFQGIEFALNNGLTVCIATPRTDV
HHHCCHHHHHHHHHHHHHHHHHEEEEEEECCCCHHHHHHHHHHHHCCCCEEEEECCCCCH
VLELAPRFRQAFPGVEIAALYGGSSDVGNLSPLIISTTHQLLRYKEAFDVIIIDEVDAFP
HHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCEEHHHHHHHHHHHHCCEEEEECCCCCC
YSIDNTLQYAVKKSAKRQSAHIYLTATPSADMKKRAESGKLDTVRIPARFHRSPLPEPTL
CCHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHCCCCCEEECCHHHCCCCCCCCCE
IWCGNWKKSLKRRKVPFRLKKWLFKHQELQQPVFLFVPSVPVLKSVVSVLKKETFRAEGV
EEECCHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHCCCC
YADDPDRNEKVNRFRESKLEVLVTTTILERGVTVKKAQVGVLGAESAVFTESALVQMAGR
CCCCCCCHHHHHHHHHHHHHEEEEHHHHHCCCEEEEEEEEEEECCHHHHHHHHHHHHHHH
AGRHPEHTDGDVCFFHYGRTKSMNAARRHIQNMNKMSKKEMLID
CCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8412657; 9384377 [H]