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The map label for this gene is ycnB [H]

Identifier: 52787218

GI number: 52787218

Start: 3369117

End: 3370568

Strand: Direct

Name: ycnB [H]

Synonym: BLi03527

Alternate gene names: 52787218

Gene position: 3369117-3370568 (Clockwise)

Preceding gene: 52787217

Following gene: 52787221

Centisome position: 79.79

GC content: 51.58

Gene sequence:

>1452_bases
ATGAGTGAAACACAGCACAAGACAAATCAATTGCCGATTGTTGCCGTCTTGATTATGGGGACATTTATCGCCATTTTGAA
TCAGACGCTTTTGACGACGGCTCTGCCTCCGATTATGAGGGACTTAAACATTACGCCGGGGCTTGCCCAATGGCTGACGA
CCGTTTTTATGCTCGTGAATGGGATCATGATTCCAGTTACGGCTTTTTTAATTGAAAAATTCACAACGAGAAAGCTGTTC
ATGGCGGCAATGTCTTTATTTACGGCCGGCACGCTGATCTGCGCCTTGTCATTCAGCTTTCCGGCGCTGATTGCGGGGCG
CGTCGTGCAGGCGGCTGGCGCCGGCATTATGATGCCATTGATGCAGACGGTGCTTTTATTGATTTTCCCAAAGGAAAAAC
GCGGATCAGCAATGGGAATGGTCGGGCTTGTGATTGCCTTTGCTCCCGCTGTCGGACCGACCCTGTCAGGCTGGATCGTC
GATCGCTATCCTTGGGAAGTATTGTTTTACCTGCTGCTTCCGTTCGCCGTGATCGACATGATTGCCGCGCACTTTATTTT
AAAAAATGTCACCGAACAGACATCGCCTAAGATGGATGTTACTTCAATCATACTGTCTTCGCTTGGCTTCGGCGGCATTT
TGTACGGCTTCAGCAGCGCCGGTGTTGCCGGCTGGACGGGTGCGGACGTGCTGGCCGGCTTCGCGGTCGGCAGCGTTGCG
CTGTTTTGGTTCATTTGGAGGCAGCTCCATTTGGAAGAGCCGATTTTGGAGTTCAGGGTATTTAAATATCCGATGTTTAC
CTTGGCGACGATTATCGGGATGGTTGTCTTTATGTCGATGATCGGAGCTGCGACGATCGTGCCGATGTATATGCAGGATA
TGCGCCATTTCACGGCGATGGAGTCGGGAATGATGCTGTTTCCGGGAGCTGTTGTGATGGGGCTGATGTCTCCGATTACC
GGAAGAATTTTTGACAAAATCGGCGCGCGGATTTTGAGCATCACCGGTTTGACGGCGATCTTCGTGACCACATTGCTCTT
GACCCATCTGACAAAGACGACGCCTTTTGCATATTTGTCTATCGTCTATGCGATTCGGATGGTCGGCATGGGGATGGTGC
TCATGCCTGTTACGACAGCCGGCTTGAACCAGCTCCCGCGCCATTTGATTCCTCACGGAACGGCCATGAACAATACAATG
AGACAGATGTCAGGATCGATCGGGACGGCTGTTCTCATCACCATCATGACACAGCGTGCGCTTCTTGACCCTGCCGGTCC
GTCTTCGGATACAGCGATGATTCACGGCGTCAATCTGGCATTTATGACCGCTGCTGCATTGTCGGGAATCGGATTGGTTC
TCTCATTCTTTATTAAGCAGCACCGCCGCGGACGGCTCGACGGCAGCAAAAGAAAACAAGCGAAAGGCCGCTTGGCCATT
CATGAGAAATGA

Upstream 100 bases:

>100_bases
TTTGCAGTTCCTTCGTTACCCTAAATGAAAAGAGAAGTTATTTCGAGTGCCGATTATTTCATAAAGTGTTATAAAAAATG
ATAAATAAGAAGGTTTTAAT

Downstream 100 bases:

>100_bases
AAAATCCCGGGTTTATAAAAACCCGGGATTTTTTTATGATTATTCGAATCCGTTAACCATTGTGTCCGGATCCGGACCGA
CGCGCTCATCTTTATTAAGA

Product: hypothetical protein

Products: Proton [Cytoplasm]; multidrug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 483; Mature: 482

Protein sequence:

>483_residues
MSETQHKTNQLPIVAVLIMGTFIAILNQTLLTTALPPIMRDLNITPGLAQWLTTVFMLVNGIMIPVTAFLIEKFTTRKLF
MAAMSLFTAGTLICALSFSFPALIAGRVVQAAGAGIMMPLMQTVLLLIFPKEKRGSAMGMVGLVIAFAPAVGPTLSGWIV
DRYPWEVLFYLLLPFAVIDMIAAHFILKNVTEQTSPKMDVTSIILSSLGFGGILYGFSSAGVAGWTGADVLAGFAVGSVA
LFWFIWRQLHLEEPILEFRVFKYPMFTLATIIGMVVFMSMIGAATIVPMYMQDMRHFTAMESGMMLFPGAVVMGLMSPIT
GRIFDKIGARILSITGLTAIFVTTLLLTHLTKTTPFAYLSIVYAIRMVGMGMVLMPVTTAGLNQLPRHLIPHGTAMNNTM
RQMSGSIGTAVLITIMTQRALLDPAGPSSDTAMIHGVNLAFMTAAALSGIGLVLSFFIKQHRRGRLDGSKRKQAKGRLAI
HEK

Sequences:

>Translated_483_residues
MSETQHKTNQLPIVAVLIMGTFIAILNQTLLTTALPPIMRDLNITPGLAQWLTTVFMLVNGIMIPVTAFLIEKFTTRKLF
MAAMSLFTAGTLICALSFSFPALIAGRVVQAAGAGIMMPLMQTVLLLIFPKEKRGSAMGMVGLVIAFAPAVGPTLSGWIV
DRYPWEVLFYLLLPFAVIDMIAAHFILKNVTEQTSPKMDVTSIILSSLGFGGILYGFSSAGVAGWTGADVLAGFAVGSVA
LFWFIWRQLHLEEPILEFRVFKYPMFTLATIIGMVVFMSMIGAATIVPMYMQDMRHFTAMESGMMLFPGAVVMGLMSPIT
GRIFDKIGARILSITGLTAIFVTTLLLTHLTKTTPFAYLSIVYAIRMVGMGMVLMPVTTAGLNQLPRHLIPHGTAMNNTM
RQMSGSIGTAVLITIMTQRALLDPAGPSSDTAMIHGVNLAFMTAAALSGIGLVLSFFIKQHRRGRLDGSKRKQAKGRLAI
HEK
>Mature_482_residues
SETQHKTNQLPIVAVLIMGTFIAILNQTLLTTALPPIMRDLNITPGLAQWLTTVFMLVNGIMIPVTAFLIEKFTTRKLFM
AAMSLFTAGTLICALSFSFPALIAGRVVQAAGAGIMMPLMQTVLLLIFPKEKRGSAMGMVGLVIAFAPAVGPTLSGWIVD
RYPWEVLFYLLLPFAVIDMIAAHFILKNVTEQTSPKMDVTSIILSSLGFGGILYGFSSAGVAGWTGADVLAGFAVGSVAL
FWFIWRQLHLEEPILEFRVFKYPMFTLATIIGMVVFMSMIGAATIVPMYMQDMRHFTAMESGMMLFPGAVVMGLMSPITG
RIFDKIGARILSITGLTAIFVTTLLLTHLTKTTPFAYLSIVYAIRMVGMGMVLMPVTTAGLNQLPRHLIPHGTAMNNTMR
QMSGSIGTAVLITIMTQRALLDPAGPSSDTAMIHGVNLAFMTAAALSGIGLVLSFFIKQHRRGRLDGSKRKQAKGRLAIH
EK

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. EmrB family [H]

Homologues:

Organism=Escherichia coli, GI1788710, Length=436, Percent_Identity=28.4403669724771, Blast_Score=155, Evalue=7e-39,
Organism=Escherichia coli, GI1789042, Length=410, Percent_Identity=26.8292682926829, Blast_Score=149, Evalue=4e-37,
Organism=Escherichia coli, GI87081983, Length=408, Percent_Identity=26.4705882352941, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI1790195, Length=419, Percent_Identity=26.491646778043, Blast_Score=122, Evalue=6e-29,
Organism=Escherichia coli, GI1788392, Length=413, Percent_Identity=26.8765133171913, Blast_Score=99, Evalue=5e-22,
Organism=Saccharomyces cerevisiae, GI6325455, Length=235, Percent_Identity=28.0851063829787, Blast_Score=68, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6323735, Length=334, Percent_Identity=21.5568862275449, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004638
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR001411 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 52406; Mature: 52275

Theoretical pI: Translated: 10.66; Mature: 10.66

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
7.5 %Met     (Translated Protein)
7.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
7.3 %Met     (Mature Protein)
7.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCC
>Mature Secondary Structure 
SETQHKTNQLPIVAVLIMGTFIAILNQTLLTTALPPIMRDLNITPGLAQWLTTVFMLVN
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHC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CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; multidrug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + multidrug [Cytoplasm] = Proton [Cytoplasm] + multidrug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]