Click here to switch to the map view.

The map label for this gene is yumC [C]

Identifier: 52787088

GI number: 52787088

Start: 3245248

End: 3246246

Strand: Direct

Name: yumC [C]

Synonym: BLi03393

Alternate gene names: 52787088

Gene position: 3245248-3246246 (Clockwise)

Preceding gene: 52787083

Following gene: 52787089

Centisome position: 76.85

GC content: 47.95

Gene sequence:

>999_bases
ATGCGTGAAGACACAAAAGTATATGATATCACAATTATCGGGGGCGGCCCTGTCGGCTTGTTTACCGCATTTTACGGCGG
AATGCGGCAAGCGAGCGTCAAAATTATTGAAAGCCTGCCGCAACTCGGCGGTCAGCTGTCCGCTTTGTATCCCGAAAAAT
ACATATACGATGTAGCCGGGTTCCCTAAAATCCGCGCTCAGGAGCTGGTCGACAATTTAAAAGAGCAAATGGCGAAATTC
GATCAGACCGTTTGTTTGGAACAAGCCGTCGAAAGCGTTGAAAAACAAGCAGACGGTATTTTCAAACTCGTCACCAACAA
AGAAATCCACTATTCTAAAACGGTGATTATTACAGCCGGAAACGGAGCATTCCAGCCGAGAAAGCTCGAGCTTGAATCTG
CGGCACAATTCGAGAATGCAAACCTTCATTACTTTATAGATGATCTGAATCAATTTGCGGGCAAGCGCGTTGCGGTATTG
GGCGGCGGCGACTCCGCCGTCGACTGGGCGCTCATGCTGGAACCGATCGCAAAAGAGGTGTCAATTATTCATCGCCGCGA
TAAATTCCGCGCACACGAGCACAGCGTCGAAAACTTGCGCAATTCTAAAGTCAATGTATTGACACCGTTTGTTCCGACCG
AGCTGATCGGCAGCGAGCGAATCGAACAGATCGTCATTGAGGAAGTGAAAGGCGAGAGAAAAGAAATCATCGATGTCGAC
GATGTGATCGTCAACTTCGGTTTTGTTTCATCTCTCGGACCAATCAAAAACTGGGGGCTTGAAATCGAGAAAAATTCGAT
CGTCGTCAAGTCCACAATGGAAACGAACATCGAGGGATTCTATGCAGCCGGCGATATCTGCACATATGAAGGGAAAGTCA
AGCTGATTGCGAGCGGATTTGGTGAAGCGCCGACCGCTGTCAACAATGCAAAAGCTTATATGGATCCTAAAGCGCGTGTG
CAGCCGCTGCACTCTACAAGCATGTTTGAAAACAAATAA

Upstream 100 bases:

>100_bases
CGGTATTATTTTCCGCGCCTAAAAAAACAGACGCGCTCGTATTTATTTTATGTGATATGATATAATTAAGAACAATTTTC
ATTTAGGGGGCATTATTTTC

Downstream 100 bases:

>100_bases
AAATGAAAAGGAGCCTGACACCGGCTCCTTTTCATTATATGATATTCAAATATGAGAAGATCGTTCCCAATATCAGCACA
ATTGTTAAGATGCCGACGAC

Product: YumC

Products: NA

Alternate protein names: FNR 2; Fd-NADP+ reductase 2

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MREDTKVYDITIIGGGPVGLFTAFYGGMRQASVKIIESLPQLGGQLSALYPEKYIYDVAGFPKIRAQELVDNLKEQMAKF
DQTVCLEQAVESVEKQADGIFKLVTNKEIHYSKTVIITAGNGAFQPRKLELESAAQFENANLHYFIDDLNQFAGKRVAVL
GGGDSAVDWALMLEPIAKEVSIIHRRDKFRAHEHSVENLRNSKVNVLTPFVPTELIGSERIEQIVIEEVKGERKEIIDVD
DVIVNFGFVSSLGPIKNWGLEIEKNSIVVKSTMETNIEGFYAAGDICTYEGKVKLIASGFGEAPTAVNNAKAYMDPKARV
QPLHSTSMFENK

Sequences:

>Translated_332_residues
MREDTKVYDITIIGGGPVGLFTAFYGGMRQASVKIIESLPQLGGQLSALYPEKYIYDVAGFPKIRAQELVDNLKEQMAKF
DQTVCLEQAVESVEKQADGIFKLVTNKEIHYSKTVIITAGNGAFQPRKLELESAAQFENANLHYFIDDLNQFAGKRVAVL
GGGDSAVDWALMLEPIAKEVSIIHRRDKFRAHEHSVENLRNSKVNVLTPFVPTELIGSERIEQIVIEEVKGERKEIIDVD
DVIVNFGFVSSLGPIKNWGLEIEKNSIVVKSTMETNIEGFYAAGDICTYEGKVKLIASGFGEAPTAVNNAKAYMDPKARV
QPLHSTSMFENK
>Mature_332_residues
MREDTKVYDITIIGGGPVGLFTAFYGGMRQASVKIIESLPQLGGQLSALYPEKYIYDVAGFPKIRAQELVDNLKEQMAKF
DQTVCLEQAVESVEKQADGIFKLVTNKEIHYSKTVIITAGNGAFQPRKLELESAAQFENANLHYFIDDLNQFAGKRVAVL
GGGDSAVDWALMLEPIAKEVSIIHRRDKFRAHEHSVENLRNSKVNVLTPFVPTELIGSERIEQIVIEEVKGERKEIIDVD
DVIVNFGFVSSLGPIKNWGLEIEKNSIVVKSTMETNIEGFYAAGDICTYEGKVKLIASGFGEAPTAVNNAKAYMDPKARV
QPLHSTSMFENK

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ferredoxin--NADP reductase type 2 family

Homologues:

Organism=Escherichia coli, GI1787114, Length=327, Percent_Identity=27.217125382263, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87081763, Length=274, Percent_Identity=28.1021897810219, Blast_Score=70, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6321898, Length=308, Percent_Identity=26.9480519480519, Blast_Score=66, Evalue=7e-12,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): FENR2_BACLD (Q65FE0)

Other databases:

- EMBL:   CP000002
- EMBL:   AE017333
- RefSeq:   YP_080493.1
- RefSeq:   YP_092917.1
- ProteinModelPortal:   Q65FE0
- STRING:   Q65FE0
- EnsemblBacteria:   EBBACT00000054261
- EnsemblBacteria:   EBBACT00000059257
- GeneID:   3027567
- GeneID:   3099711
- GenomeReviews:   AE017333_GR
- GenomeReviews:   CP000002_GR
- KEGG:   bld:BLi03393
- KEGG:   bli:BL03143
- NMPDR:   fig|279010.5.peg.3642
- eggNOG:   COG0492
- GeneTree:   EBGT00050000000432
- HOGENOM:   HBG669726
- OMA:   FQVFELG
- ProtClustDB:   CLSK2460953
- BioCyc:   BLIC279010-1:BLI03393-MONOMER
- BioCyc:   BLIC279010:BL03143-MONOMER
- HAMAP:   MF_01685
- InterPro:   IPR013027
- InterPro:   IPR022890
- InterPro:   IPR001327
- InterPro:   IPR000103
- PRINTS:   PR00368
- PRINTS:   PR00469

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2

EC number: =1.18.1.2

Molecular weight: Translated: 36806; Mature: 36806

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: NA

Important sites: BINDING 37-37 BINDING 45-45 BINDING 50-50 BINDING 90-90 BINDING 124-124 BINDING 285-285 BINDING 326-326

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREDTKVYDITIIGGGPVGLFTAFYGGMRQASVKIIESLPQLGGQLSALYPEKYIYDVAG
CCCCCEEEEEEEECCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCEECCCCHHHEEECCC
FPKIRAQELVDNLKEQMAKFDQTVCLEQAVESVEKQADGIFKLVTNKEIHYSKTVIITAG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCEEEEEEEEEECC
NGAFQPRKLELESAAQFENANLHYFIDDLNQFAGKRVAVLGGGDSAVDWALMLEPIAKEV
CCCCCCCEECHHHHHHCCCCCEEEEEHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHH
SIIHRRDKFRAHEHSVENLRNSKVNVLTPFVPTELIGSERIEQIVIEEVKGERKEIIDVD
HHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHHHCCCHHHHCCHH
DVIVNFGFVSSLGPIKNWGLEIEKNSIVVKSTMETNIEGFYAAGDICTYEGKVKLIASGF
HHHHHHHHHHCCCCHHHCCEEEECCCEEEEEEHHCCCCEEEEECCEEEECCCEEEEECCC
GEAPTAVNNAKAYMDPKARVQPLHSTSMFENK
CCCCCCCCCCHHHCCCHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MREDTKVYDITIIGGGPVGLFTAFYGGMRQASVKIIESLPQLGGQLSALYPEKYIYDVAG
CCCCCEEEEEEEECCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCEECCCCHHHEEECCC
FPKIRAQELVDNLKEQMAKFDQTVCLEQAVESVEKQADGIFKLVTNKEIHYSKTVIITAG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCEEEEEEEEEECC
NGAFQPRKLELESAAQFENANLHYFIDDLNQFAGKRVAVLGGGDSAVDWALMLEPIAKEV
CCCCCCCEECHHHHHHCCCCCEEEEEHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHH
SIIHRRDKFRAHEHSVENLRNSKVNVLTPFVPTELIGSERIEQIVIEEVKGERKEIIDVD
HHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHHHCCCHHHHCCHH
DVIVNFGFVSSLGPIKNWGLEIEKNSIVVKSTMETNIEGFYAAGDICTYEGKVKLIASGF
HHHHHHHHHHCCCCHHHCCEEEECCCEEEEEEHHCCCCEEEEECCEEEECCCEEEEECCC
GEAPTAVNNAKAYMDPKARVQPLHSTSMFENK
CCCCCCCCCCHHHCCCHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA