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The map label for this gene is coaE

Identifier: 52786783

GI number: 52786783

Start: 2937999

End: 2938604

Strand: Reverse

Name: coaE

Synonym: BLi03054

Alternate gene names: 52786783

Gene position: 2938604-2937999 (Counterclockwise)

Preceding gene: 52786784

Following gene: 52786781

Centisome position: 69.59

GC content: 48.68

Gene sequence:

>606_bases
TTGACATTGGTCATCGGGTTAACCGGGGGGATTGCCAGCGGCAAAAGCACTGTCGCGCAAATGTTCCAGCAGTGCGGCAT
CACGGTCGTCGATGCGGACGTGATCGCGAAAGAGGCCGTTGAACAGGGGATGCCCGCTTATCAGAAAATCGCTGAGACAT
TTGGTGAAGGCGTGCTGCTTGAAACAGGCGATATCGACCGGAGAAAACTTGGAGAAATTGTTTTTGCTAATGAAGAAAAA
AGGCTGCAGTTAAATGCAATCGTCCATCCCGAAGTGAGAAAAATGATGATCAAGCAGCGCGACGAAGCCATCCGGGCCGG
TGAACGGTTTGTTGTTCTCGATATTCCGCTTTTATATGAAAGCGGGCTCGAACATTTGACAGATAAAGTGATCGTTGTCT
GGGTTCCGATGGAGCTTCAGCTTGAGCGGCTGATGAAAAGAAACCGGCTTAATAAAGACGAGGCGCTGAACAGAATTCAC
GCCCAGCAATCTCTTGACGAAAAAAAGAAAAGGGCAGACGCGGTGATCGATAACAGCGGCAGTCTGAAAGATACAGAAGC
GCAGCTTCATCAGCTGCTTGATACATGGTCAAATATTGAAAAGTGA

Upstream 100 bases:

>100_bases
TTTTATCGAAATGGAACTGGATGGATAAACTGACCTTTCTTCCCGGTATATTGCTGATTATGATCGGCATCTGGAAACTG
TAAGAAGGAGGTGCAGGCCT

Downstream 100 bases:

>100_bases
GCGCAATGTCGCGCTCACTTTTTTGATTAGTCTTTTTTAAACTGGCTGTAATTCGCATAGTACAGAGCGGTGCGCTGCGC
ACCTGCGTACCGTTTGGCAA

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase

Number of amino acids: Translated: 201; Mature: 200

Protein sequence:

>201_residues
MTLVIGLTGGIASGKSTVAQMFQQCGITVVDADVIAKEAVEQGMPAYQKIAETFGEGVLLETGDIDRRKLGEIVFANEEK
RLQLNAIVHPEVRKMMIKQRDEAIRAGERFVVLDIPLLYESGLEHLTDKVIVVWVPMELQLERLMKRNRLNKDEALNRIH
AQQSLDEKKKRADAVIDNSGSLKDTEAQLHQLLDTWSNIEK

Sequences:

>Translated_201_residues
MTLVIGLTGGIASGKSTVAQMFQQCGITVVDADVIAKEAVEQGMPAYQKIAETFGEGVLLETGDIDRRKLGEIVFANEEK
RLQLNAIVHPEVRKMMIKQRDEAIRAGERFVVLDIPLLYESGLEHLTDKVIVVWVPMELQLERLMKRNRLNKDEALNRIH
AQQSLDEKKKRADAVIDNSGSLKDTEAQLHQLLDTWSNIEK
>Mature_200_residues
TLVIGLTGGIASGKSTVAQMFQQCGITVVDADVIAKEAVEQGMPAYQKIAETFGEGVLLETGDIDRRKLGEIVFANEEKR
LQLNAIVHPEVRKMMIKQRDEAIRAGERFVVLDIPLLYESGLEHLTDKVIVVWVPMELQLERLMKRNRLNKDEALNRIHA
QQSLDEKKKRADAVIDNSGSLKDTEAQLHQLLDTWSNIEK

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain

Homologues:

Organism=Homo sapiens, GI191252797, Length=188, Percent_Identity=47.8723404255319, Blast_Score=180, Evalue=9e-46,
Organism=Homo sapiens, GI191252795, Length=188, Percent_Identity=47.8723404255319, Blast_Score=180, Evalue=9e-46,
Organism=Homo sapiens, GI110227607, Length=198, Percent_Identity=31.3131313131313, Blast_Score=103, Evalue=9e-23,
Organism=Homo sapiens, GI110227605, Length=198, Percent_Identity=31.3131313131313, Blast_Score=102, Evalue=2e-22,
Organism=Homo sapiens, GI110227603, Length=198, Percent_Identity=31.3131313131313, Blast_Score=102, Evalue=2e-22,
Organism=Homo sapiens, GI110227601, Length=198, Percent_Identity=31.3131313131313, Blast_Score=102, Evalue=2e-22,
Organism=Homo sapiens, GI205277394, Length=198, Percent_Identity=31.3131313131313, Blast_Score=102, Evalue=2e-22,
Organism=Escherichia coli, GI1786292, Length=181, Percent_Identity=39.7790055248619, Blast_Score=129, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI17554944, Length=193, Percent_Identity=40.4145077720207, Blast_Score=162, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI25143409, Length=189, Percent_Identity=32.2751322751323, Blast_Score=82, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6320402, Length=196, Percent_Identity=40.3061224489796, Blast_Score=142, Evalue=4e-35,
Organism=Drosophila melanogaster, GI24644728, Length=187, Percent_Identity=41.1764705882353, Blast_Score=159, Evalue=1e-39,
Organism=Drosophila melanogaster, GI24658602, Length=162, Percent_Identity=37.6543209876543, Blast_Score=105, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAE_BACLD (Q65G95)

Other databases:

- EMBL:   AE017333
- EMBL:   CP000002
- RefSeq:   YP_080198.1
- RefSeq:   YP_092612.1
- ProteinModelPortal:   Q65G95
- SMR:   Q65G95
- STRING:   Q65G95
- EnsemblBacteria:   EBBACT00000054741
- EnsemblBacteria:   EBBACT00000058527
- GeneID:   3028979
- GeneID:   3098652
- GenomeReviews:   AE017333_GR
- GenomeReviews:   CP000002_GR
- KEGG:   bld:BLi03054
- KEGG:   bli:BL00391
- NMPDR:   fig|279010.5.peg.3417
- eggNOG:   COG0237
- GeneTree:   EBGT00050000001187
- HOGENOM:   HBG650290
- OMA:   VVVYCDP
- ProtClustDB:   PRK00081
- BioCyc:   BLIC279010-1:BLI03054-MONOMER
- BioCyc:   BLIC279010:BL00391-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00376
- InterPro:   IPR001977
- TIGRFAMs:   TIGR00152

Pfam domain/function: PF01121 CoaE

EC number: =2.7.1.24

Molecular weight: Translated: 22617; Mature: 22486

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: PS51219 DPCK; PS01294 COAE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLVIGLTGGIASGKSTVAQMFQQCGITVVDADVIAKEAVEQGMPAYQKIAETFGEGVLL
CEEEEEECCCCCCCHHHHHHHHHHCCCEEECHHHHHHHHHHCCCCHHHHHHHHHCCCEEE
ETGDIDRRKLGEIVFANEEKRLQLNAIVHPEVRKMMIKQRDEAIRAGERFVVLDIPLLYE
ECCCCCHHHHCCEEEECCCCCEEEEEEECHHHHHHHHHHHHHHHHCCCEEEEEECHHHHH
SGLEHLTDKVIVVWVPMELQLERLMKRNRLNKDEALNRIHAQQSLDEKKKRADAVIDNSG
HHHHHHCCCEEEEEECHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
SLKDTEAQLHQLLDTWSNIEK
CCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TLVIGLTGGIASGKSTVAQMFQQCGITVVDADVIAKEAVEQGMPAYQKIAETFGEGVLL
EEEEEECCCCCCCHHHHHHHHHHCCCEEECHHHHHHHHHHCCCCHHHHHHHHHCCCEEE
ETGDIDRRKLGEIVFANEEKRLQLNAIVHPEVRKMMIKQRDEAIRAGERFVVLDIPLLYE
ECCCCCHHHHCCEEEECCCCCEEEEEEECHHHHHHHHHHHHHHHHCCCEEEEEECHHHHH
SGLEHLTDKVIVVWVPMELQLERLMKRNRLNKDEALNRIHAQQSLDEKKKRADAVIDNSG
HHHHHHCCCEEEEEECHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
SLKDTEAQLHQLLDTWSNIEK
CCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA