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The map label for this gene is gapB [H]

Identifier: 52786781

GI number: 52786781

Start: 2935214

End: 2936236

Strand: Reverse

Name: gapB [H]

Synonym: BLi03052

Alternate gene names: 52786781

Gene position: 2936236-2935214 (Counterclockwise)

Preceding gene: 52786783

Following gene: 52786780

Centisome position: 69.54

GC content: 48.88

Gene sequence:

>1023_bases
ATGAAAGTGAAAGTTGCGATAAACGGATTCGGCCGGATCGGCAGAATGGTGTTTAGAAAAGCGATGCTTGATGAACAGAT
TGACATTGCGGCGATCAATGCGAGCTACCCTCCGGAAACGCTCGCTCATTTAATAAAGTATGACACAAATCACGGCCGTT
ATGAACTTGATGTAAAGGCTGGAGAAGACTGCCTGTTCGTTAACGGTAAAAAGGTCATGCTGACCAATCAGAGGGACCCT
AAGCTTCTTCCGTGGGCACAATACGGAATCGACATCGCCGTGGAAGCGACGGGGAAATTCAACTCAAAGGAAAAAGCGGA
AGCACATATTGAAGCCGGCGCGAAAAAAGTTATTTTGACGGCGCCGGGCAAAAATGAAGACATCACAATCGTGATGGGCG
TCAACGAACGCGATTTTGATGCGGAGCGTCATACGATTATTTCAAACGCTTCCTGTACGACGAATTGTCTCGCTCCAGTC
GCAAAAGTGCTTGATGATGCATTCGGCATTGAAAACGGCCTGGTGACAACCGTACACGCTTTTACAAATGATCAAAAAAA
TATTGATAATCCGCACAAAGACTTGAGGAGCGCGCGCGCCTGCGGATCTTCGATCATTCCGACAACGACAGGCGCCGCGA
AAGCGCTGTCACTTGTCATGCCCCATTTAAAGGGTAGAATGCACGGCCTGGCCCTGCGCGTTCCCGTCTCAAATGTGTCG
CTCGTTGACCTTGTGGCTGATTTGAAAAGCGATGTGACGGCGGAGGATATTAATGAGGCGTTCCGCATGGCGGCGGCAGG
CTCCATGTCCGGGATCATCGATGTATGCGATGAACCGCTCGTTTCATCCGATTTTAATACGAATCCATACTCGGCGGTGA
TCGACAGTCTTTCGACAATGGTGCTTGAAAACAGAAAGGTGAAAGTGCTTGCATGGTATGACAATGAATGGGGATATTCG
TGCAGGGTTGTCGATTTGATCAGATACGCGGCTTCAAGAATGAAACACCCCTCAGCTGTATAA

Upstream 100 bases:

>100_bases
GTGAAAGCAACAAATGGTATGGCTAATTAAAAATAATGTGTTATACTTATTTTGAATAAATCATGATGTGGAATGACATA
AAATAAGGGGTGCATATTTG

Downstream 100 bases:

>100_bases
AATAAGAGCATGGACGGATAAAAAAATAAATACCCCTTAACCATCAAATGATAAAACCGCCTTGCAAAAAATATTCAAAC
AAAGTATACTATTTTTCGTG

Product: glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase; GAPDH [H]

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MKVKVAINGFGRIGRMVFRKAMLDEQIDIAAINASYPPETLAHLIKYDTNHGRYELDVKAGEDCLFVNGKKVMLTNQRDP
KLLPWAQYGIDIAVEATGKFNSKEKAEAHIEAGAKKVILTAPGKNEDITIVMGVNERDFDAERHTIISNASCTTNCLAPV
AKVLDDAFGIENGLVTTVHAFTNDQKNIDNPHKDLRSARACGSSIIPTTTGAAKALSLVMPHLKGRMHGLALRVPVSNVS
LVDLVADLKSDVTAEDINEAFRMAAAGSMSGIIDVCDEPLVSSDFNTNPYSAVIDSLSTMVLENRKVKVLAWYDNEWGYS
CRVVDLIRYAASRMKHPSAV

Sequences:

>Translated_340_residues
MKVKVAINGFGRIGRMVFRKAMLDEQIDIAAINASYPPETLAHLIKYDTNHGRYELDVKAGEDCLFVNGKKVMLTNQRDP
KLLPWAQYGIDIAVEATGKFNSKEKAEAHIEAGAKKVILTAPGKNEDITIVMGVNERDFDAERHTIISNASCTTNCLAPV
AKVLDDAFGIENGLVTTVHAFTNDQKNIDNPHKDLRSARACGSSIIPTTTGAAKALSLVMPHLKGRMHGLALRVPVSNVS
LVDLVADLKSDVTAEDINEAFRMAAAGSMSGIIDVCDEPLVSSDFNTNPYSAVIDSLSTMVLENRKVKVLAWYDNEWGYS
CRVVDLIRYAASRMKHPSAV
>Mature_340_residues
MKVKVAINGFGRIGRMVFRKAMLDEQIDIAAINASYPPETLAHLIKYDTNHGRYELDVKAGEDCLFVNGKKVMLTNQRDP
KLLPWAQYGIDIAVEATGKFNSKEKAEAHIEAGAKKVILTAPGKNEDITIVMGVNERDFDAERHTIISNASCTTNCLAPV
AKVLDDAFGIENGLVTTVHAFTNDQKNIDNPHKDLRSARACGSSIIPTTTGAAKALSLVMPHLKGRMHGLALRVPVSNVS
LVDLVADLKSDVTAEDINEAFRMAAAGSMSGIIDVCDEPLVSSDFNTNPYSAVIDSLSTMVLENRKVKVLAWYDNEWGYS
CRVVDLIRYAASRMKHPSAV

Specific function: More active in anabolism [H]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=334, Percent_Identity=45.2095808383234, Blast_Score=298, Evalue=7e-81,
Organism=Homo sapiens, GI7657116, Length=336, Percent_Identity=43.75, Blast_Score=291, Evalue=5e-79,
Organism=Escherichia coli, GI1788079, Length=330, Percent_Identity=47.5757575757576, Blast_Score=313, Evalue=9e-87,
Organism=Escherichia coli, GI1789295, Length=329, Percent_Identity=45.5927051671732, Blast_Score=301, Evalue=5e-83,
Organism=Caenorhabditis elegans, GI17534679, Length=339, Percent_Identity=45.4277286135693, Blast_Score=300, Evalue=6e-82,
Organism=Caenorhabditis elegans, GI17534677, Length=339, Percent_Identity=45.1327433628319, Blast_Score=300, Evalue=8e-82,
Organism=Caenorhabditis elegans, GI32566163, Length=339, Percent_Identity=45.4277286135693, Blast_Score=294, Evalue=3e-80,
Organism=Caenorhabditis elegans, GI17568413, Length=339, Percent_Identity=45.4277286135693, Blast_Score=294, Evalue=4e-80,
Organism=Saccharomyces cerevisiae, GI6321631, Length=331, Percent_Identity=45.9214501510574, Blast_Score=315, Evalue=6e-87,
Organism=Saccharomyces cerevisiae, GI6322409, Length=331, Percent_Identity=45.619335347432, Blast_Score=315, Evalue=7e-87,
Organism=Saccharomyces cerevisiae, GI6322468, Length=331, Percent_Identity=46.2235649546828, Blast_Score=315, Evalue=8e-87,
Organism=Drosophila melanogaster, GI19922412, Length=328, Percent_Identity=43.9024390243902, Blast_Score=284, Evalue=7e-77,
Organism=Drosophila melanogaster, GI17933600, Length=332, Percent_Identity=43.9759036144578, Blast_Score=282, Evalue=2e-76,
Organism=Drosophila melanogaster, GI18110149, Length=332, Percent_Identity=43.9759036144578, Blast_Score=282, Evalue=2e-76,
Organism=Drosophila melanogaster, GI85725000, Length=332, Percent_Identity=43.9759036144578, Blast_Score=282, Evalue=2e-76,
Organism=Drosophila melanogaster, GI22023983, Length=332, Percent_Identity=43.9759036144578, Blast_Score=282, Evalue=2e-76,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.59 [H]

Molecular weight: Translated: 37089; Mature: 37089

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVKVAINGFGRIGRMVFRKAMLDEQIDIAAINASYPPETLAHLIKYDTNHGRYELDVKA
CEEEEEECCCHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHCCCCCCEEEEEEEC
GEDCLFVNGKKVMLTNQRDPKLLPWAQYGIDIAVEATGKFNSKEKAEAHIEAGAKKVILT
CCCEEEECCCEEEEECCCCCCCCCHHHCCEEEEEEECCCCCCHHHHHHHHHCCCEEEEEE
APGKNEDITIVMGVNERDFDAERHTIISNASCTTNCLAPVAKVLDDAFGIENGLVTTVHA
CCCCCCCEEEEEECCCCCCCCCHHEEECCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEE
FTNDQKNIDNPHKDLRSARACGSSIIPTTTGAAKALSLVMPHLKGRMHGLALRVPVSNVS
ECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCH
LVDLVADLKSDVTAEDINEAFRMAAAGSMSGIIDVCDEPLVSSDFNTNPYSAVIDSLSTM
HHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHH
VLENRKVKVLAWYDNEWGYSCRVVDLIRYAASRMKHPSAV
HHCCCCEEEEEEECCCCCCEEHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKVKVAINGFGRIGRMVFRKAMLDEQIDIAAINASYPPETLAHLIKYDTNHGRYELDVKA
CEEEEEECCCHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHCCCCCCEEEEEEEC
GEDCLFVNGKKVMLTNQRDPKLLPWAQYGIDIAVEATGKFNSKEKAEAHIEAGAKKVILT
CCCEEEECCCEEEEECCCCCCCCCHHHCCEEEEEEECCCCCCHHHHHHHHHCCCEEEEEE
APGKNEDITIVMGVNERDFDAERHTIISNASCTTNCLAPVAKVLDDAFGIENGLVTTVHA
CCCCCCCEEEEEECCCCCCCCCHHEEECCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEE
FTNDQKNIDNPHKDLRSARACGSSIIPTTTGAAKALSLVMPHLKGRMHGLALRVPVSNVS
ECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCH
LVDLVADLKSDVTAEDINEAFRMAAAGSMSGIIDVCDEPLVSSDFNTNPYSAVIDSLSTM
HHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHH
VLENRKVKVLAWYDNEWGYSCRVVDLIRYAASRMKHPSAV
HHCCCCEEEEEEECCCCCCEEHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377; 10799476 [H]