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The map label for this gene is speD

Identifier: 52786780

GI number: 52786780

Start: 2934591

End: 2934977

Strand: Reverse

Name: speD

Synonym: BLi03051

Alternate gene names: 52786780

Gene position: 2934977-2934591 (Counterclockwise)

Preceding gene: 52786781

Following gene: 52786779

Centisome position: 69.51

GC content: 44.7

Gene sequence:

>387_bases
ATGGAAACAATGGGGCGTCACGTTATCTCCGAACTGTGGGGATGCGATTTTGATAAGCTGAATGACATGGATTTTATTGA
AAAAACGTTTGTAAATGCGGCACTGAAGTCAGGTGCTGAGGTACGTGAGGTAGCCTTTCATAAGTTTGCGCCTCAAGGTG
TAAGCGGGGTCGTGATTATTTCAGAATCTCACTTGACCATTCACAGTTTTCCTGAACACGGATATGCCAGCATTGATGTT
TATACTTGCGGAGATTTAGATCCGAACGTAGCTGCCGATTATATCGCAGAAGAGTTAAGAGCGGAAACAAGAGAGAACAT
TGAAATACCGAGAGGCATGGGACCTGTTCAGGTGAAACAGGCCAAAGCCAAAGCACAGGCACTTTAA

Upstream 100 bases:

>100_bases
GGGTTAGGACCTCTCCGGACTAACTTTCCCCCGTGGTAATTGACCGGTTCAGTTGCTTGGAAATTCACTTTTTTAATTCT
TGTTAAGGGGGGGCCATGCT

Downstream 100 bases:

>100_bases
TGCCGATAGAGGAGCTGGATGAAAAAGCGGACACCGCTTTTAAAATCCGCTCCTTTTTCTTTCCTCTCCCGAAAATCCCC
AAAACATATTCCCCGGCATT

Product: S-adenosylmethionine decarboxylase proenzyme

Products: NA

Alternate protein names: AdoMetDC; SAMDC

Number of amino acids: Translated: 128; Mature: 128

Protein sequence:

>128_residues
METMGRHVISELWGCDFDKLNDMDFIEKTFVNAALKSGAEVREVAFHKFAPQGVSGVVIISESHLTIHSFPEHGYASIDV
YTCGDLDPNVAADYIAEELRAETRENIEIPRGMGPVQVKQAKAKAQAL

Sequences:

>Translated_128_residues
METMGRHVISELWGCDFDKLNDMDFIEKTFVNAALKSGAEVREVAFHKFAPQGVSGVVIISESHLTIHSFPEHGYASIDV
YTCGDLDPNVAADYIAEELRAETRENIEIPRGMGPVQVKQAKAKAQAL
>Mature_128_residues
METMGRHVISELWGCDFDKLNDMDFIEKTFVNAALKSGAEVREVAFHKFAPQGVSGVVIISESHLTIHSFPEHGYASIDV
YTCGDLDPNVAADYIAEELRAETRENIEIPRGMGPVQVKQAKAKAQAL

Specific function: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine

COG id: COG1586

COG function: function code E; S-adenosylmethionine decarboxylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SPEH_BACLD (Q65G98)

Other databases:

- EMBL:   CP000002
- EMBL:   AE017333
- RefSeq:   YP_080195.2
- RefSeq:   YP_092609.1
- HSSP:   Q9WZC3
- ProteinModelPortal:   Q65G98
- SMR:   Q65G98
- STRING:   Q65G98
- EnsemblBacteria:   EBBACT00000057067
- EnsemblBacteria:   EBBACT00000060321
- GeneID:   3028918
- GeneID:   3098649
- GenomeReviews:   AE017333_GR
- GenomeReviews:   CP000002_GR
- KEGG:   bld:BLi03051
- KEGG:   bli:BL00389
- NMPDR:   fig|279010.5.peg.3414
- eggNOG:   COG1586
- GeneTree:   EBGT00050000001345
- HOGENOM:   HBG485559
- ProtClustDB:   PRK03124
- BioCyc:   BLIC279010-1:BLI03051-MONOMER
- HAMAP:   MF_00464
- InterPro:   IPR003826
- InterPro:   IPR016067
- InterPro:   IPR017716
- Gene3D:   G3DSA:3.60.90.10
- TIGRFAMs:   TIGR03330

Pfam domain/function: PF02675 AdoMet_dc; SSF56276 S-AdenosylMet_decarbase_core

EC number: =4.1.1.50

Molecular weight: Translated: 14121; Mature: 14121

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: ACT_SITE 63-63 ACT_SITE 68-68 ACT_SITE 83-83

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METMGRHVISELWGCDFDKLNDMDFIEKTFVNAALKSGAEVREVAFHKFAPQGVSGVVII
CCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCEEEEE
SESHLTIHSFPEHGYASIDVYTCGDLDPNVAADYIAEELRAETRENIEIPRGMGPVQVKQ
ECCCEEEECCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHH
AKAKAQAL
HHHHHCCC
>Mature Secondary Structure
METMGRHVISELWGCDFDKLNDMDFIEKTFVNAALKSGAEVREVAFHKFAPQGVSGVVII
CCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCEEEEE
SESHLTIHSFPEHGYASIDVYTCGDLDPNVAADYIAEELRAETRENIEIPRGMGPVQVKQ
ECCCEEEECCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHH
AKAKAQAL
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA