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The map label for this gene is ysbB [H]

Identifier: 52786766

GI number: 52786766

Start: 2920253

End: 2920936

Strand: Reverse

Name: ysbB [H]

Synonym: BLi03036

Alternate gene names: 52786766

Gene position: 2920936-2920253 (Counterclockwise)

Preceding gene: 52786767

Following gene: 52786765

Centisome position: 69.17

GC content: 49.71

Gene sequence:

>684_bases
ATGACACCTTATTTCGGTATCGTCGTTTCACTGGCCGCATTTGGCACCGGCACTTTTTTATTTAAAAAATCAAATGGTTT
TTTCTTATTCACGCCTCTGTTTGTCGCGATGATTCTTGGGATCGCGTTTTTAAAAATCGGCGGTTTTTCATATGAGGACT
ACAAGAGCGGCGGAGACATCATTAAGTTCTTTTTGGAGCCCGCCACAATTGCGTTCGCCATTCCTTTATATAAACAGGCG
GACAAGTTGAAAAAGTATTGGCTGCAAATCCTTGGTGCCATTATTGCAGGCTCCGTCTGCTCGGTTGCCGTCGTCTATCT
GATCGCAAACGCGCTCCATCTTGACGGAGCCGTCATGAAAAGCATGCTGCCCCAGGCCGCCACAACGGCGATTGCTCTTC
CTTTATCAAAAGGGATCGGCGGGATTCAAGATATTACGGCCTTCGCCGTCATCTTTAACGCAGTGATCGTCTATGCGCTC
GGCGCGCTTTTTTTGAAAATCTTCAAAGTGCAGCATCCGATCGCCAAAGGGTTGGCGCTCGGAACATCAGGACATGCCCT
CGGCGTCGCCGTCGGAATTGAGATGGGGGAAGTCGAAGCGGCAATGGCGAGTATTGCAGTTGTCGTCGTCGGCGTCGTGA
CCGTGTTTGTCGTTCCGTTATGTGTTCAAATGATCGGCGGATAG

Upstream 100 bases:

>100_bases
CACAGTTCATTCTGTCTGTCGGCAAAAAGGACCGTCAAGACACACGAGTTGAACCAGCCAAAAAAACAGCATCTTGAATC
AATAGGAGGTTCTTTACGCT

Downstream 100 bases:

>100_bases
AGCGGCTGAAAGAAAAATAAAAAAATAGCATTGCTATTTGAAATGTGTCCTGATATAATAGCAAATGTTGTGATAAATTT
TATATCTTGACTTGCAGGAT

Product: antiholin-like protein LrgB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 227; Mature: 226

Protein sequence:

>227_residues
MTPYFGIVVSLAAFGTGTFLFKKSNGFFLFTPLFVAMILGIAFLKIGGFSYEDYKSGGDIIKFFLEPATIAFAIPLYKQA
DKLKKYWLQILGAIIAGSVCSVAVVYLIANALHLDGAVMKSMLPQAATTAIALPLSKGIGGIQDITAFAVIFNAVIVYAL
GALFLKIFKVQHPIAKGLALGTSGHALGVAVGIEMGEVEAAMASIAVVVVGVVTVFVVPLCVQMIGG

Sequences:

>Translated_227_residues
MTPYFGIVVSLAAFGTGTFLFKKSNGFFLFTPLFVAMILGIAFLKIGGFSYEDYKSGGDIIKFFLEPATIAFAIPLYKQA
DKLKKYWLQILGAIIAGSVCSVAVVYLIANALHLDGAVMKSMLPQAATTAIALPLSKGIGGIQDITAFAVIFNAVIVYAL
GALFLKIFKVQHPIAKGLALGTSGHALGVAVGIEMGEVEAAMASIAVVVVGVVTVFVVPLCVQMIGG
>Mature_226_residues
TPYFGIVVSLAAFGTGTFLFKKSNGFFLFTPLFVAMILGIAFLKIGGFSYEDYKSGGDIIKFFLEPATIAFAIPLYKQAD
KLKKYWLQILGAIIAGSVCSVAVVYLIANALHLDGAVMKSMLPQAATTAIALPLSKGIGGIQDITAFAVIFNAVIVYALG
ALFLKIFKVQHPIAKGLALGTSGHALGVAVGIEMGEVEAAMASIAVVVVGVVTVFVVPLCVQMIGG

Specific function: Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell

COG id: COG1346

COG function: function code M; Putative effector of murein hydrolase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CidB/LrgB family. LrgB subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788464, Length=193, Percent_Identity=35.2331606217617, Blast_Score=123, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007300 [H]

Pfam domain/function: PF04172 LrgB [H]

EC number: NA

Molecular weight: Translated: 23744; Mature: 23613

Theoretical pI: Translated: 9.31; Mature: 9.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPYFGIVVSLAAFGTGTFLFKKSNGFFLFTPLFVAMILGIAFLKIGGFSYEDYKSGGDI
CCCHHHHHHHHHHHCCCEEEEEECCCEEEHHHHHHHHHHHHHHHHHCCCCCHHHHCCHHH
IKFFLEPATIAFAIPLYKQADKLKKYWLQILGAIIAGSVCSVAVVYLIANALHLDGAVMK
HHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SMLPQAATTAIALPLSKGIGGIQDITAFAVIFNAVIVYALGALFLKIFKVQHPIAKGLAL
HHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GTSGHALGVAVGIEMGEVEAAMASIAVVVVGVVTVFVVPLCVQMIGG
CCCCCHHHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TPYFGIVVSLAAFGTGTFLFKKSNGFFLFTPLFVAMILGIAFLKIGGFSYEDYKSGGDI
CCHHHHHHHHHHHCCCEEEEEECCCEEEHHHHHHHHHHHHHHHHHCCCCCHHHHCCHHH
IKFFLEPATIAFAIPLYKQADKLKKYWLQILGAIIAGSVCSVAVVYLIANALHLDGAVMK
HHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SMLPQAATTAIALPLSKGIGGIQDITAFAVIFNAVIVYALGALFLKIFKVQHPIAKGLAL
HHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GTSGHALGVAVGIEMGEVEAAMASIAVVVVGVVTVFVVPLCVQMIGG
CCCCCHHHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]