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The map label for this gene is infC [H]

Identifier: 52786765

GI number: 52786765

Start: 2919399

End: 2920034

Strand: Reverse

Name: infC [H]

Synonym: BLi03035

Alternate gene names: 52786765

Gene position: 2920034-2919399 (Counterclockwise)

Preceding gene: 52786766

Following gene: 52786764

Centisome position: 69.15

GC content: 47.48

Gene sequence:

>636_bases
ATGCAATGTTCGCAGTGTGGGTGTTTCGATGCCCGCACTTTTTGTTTGCCTGTGGAATGCAAAGAAACGGTCAAAATGAG
TTGTGAAATCAATTCAAAGATTCTATGGAGGTGGCTCATTATTAGCAAAGATCAATTGGTTAATGAGGGTATCCGTGCGC
GTGAAGTTCGTTTGATCGGACAAAATGGCGATCAGCTTGGGATCAAATCCCGCCAGGAAGCACTGGAAATTGCGGGTCGC
GCAAATCTTGACCTTGTGTTGGTTGCAGCGAATGCAAAACCGCCTGTCTGCCGGATCATGGACTATGGAAAGTACAGATT
CGAGCAGCAGAAGAAGGAAAAGGAAGCACGCAAAAATCAAAAAATCATTAACTTAAAAGAAGTTCGGCTGAGCCCTGGTA
TTGAAGAACACGACTTCAATACAAAGCTTCGCAACGCCATCAAGTTCCTGCAAAAAGGGGACAAAGTGAAAGCGTCCATC
CGCTTTAAAGGCCGTGCGATCACGCATAAAGAAATCGGGCAGCGCGTGCTGGACCGTTTTTCAGAAGCCTGCGCGGAAGT
GGCGACTGTTGAAACGAAGCCGAAAATGGACGGCCGCAGCATGTTCCTGGTGCTCGCGCCTAAAACTGAAAAGTAA

Upstream 100 bases:

>100_bases
TAATGAATTGAATATATATCAACAAGCAGAAGCACCCGCTTCTCACCTGATTGACACATTCTTGTAGTTGGCAGGTTAAA
CGTACATTTCTTATTTTTCT

Downstream 100 bases:

>100_bases
TTAAGGAGGAAACATCCATGCCAAAAATGAAAACTCACCGCGGATCTGCGAAACGTTTTAAAAAGACAGGTTCCGGGAAA
CTGAAACGTTCTCATGCATA

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 211; Mature: 211

Protein sequence:

>211_residues
MQCSQCGCFDARTFCLPVECKETVKMSCEINSKILWRWLIISKDQLVNEGIRAREVRLIGQNGDQLGIKSRQEALEIAGR
ANLDLVLVAANAKPPVCRIMDYGKYRFEQQKKEKEARKNQKIINLKEVRLSPGIEEHDFNTKLRNAIKFLQKGDKVKASI
RFKGRAITHKEIGQRVLDRFSEACAEVATVETKPKMDGRSMFLVLAPKTEK

Sequences:

>Translated_211_residues
MQCSQCGCFDARTFCLPVECKETVKMSCEINSKILWRWLIISKDQLVNEGIRAREVRLIGQNGDQLGIKSRQEALEIAGR
ANLDLVLVAANAKPPVCRIMDYGKYRFEQQKKEKEARKNQKIINLKEVRLSPGIEEHDFNTKLRNAIKFLQKGDKVKASI
RFKGRAITHKEIGQRVLDRFSEACAEVATVETKPKMDGRSMFLVLAPKTEK
>Mature_211_residues
MQCSQCGCFDARTFCLPVECKETVKMSCEINSKILWRWLIISKDQLVNEGIRAREVRLIGQNGDQLGIKSRQEALEIAGR
ANLDLVLVAANAKPPVCRIMDYGKYRFEQQKKEKEARKNQKIINLKEVRLSPGIEEHDFNTKLRNAIKFLQKGDKVKASI
RFKGRAITHKEIGQRVLDRFSEACAEVATVETKPKMDGRSMFLVLAPKTEK

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=163, Percent_Identity=52.1472392638037, Blast_Score=160, Evalue=5e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 24097; Mature: 24097

Theoretical pI: Translated: 10.12; Mature: 10.12

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
3.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQCSQCGCFDARTFCLPVECKETVKMSCEINSKILWRWLIISKDQLVNEGIRAREVRLIG
CCCCCCCCCCCCEEEEECCCHHHEEEEEECCCEEEEEEEEECCHHHHHCCCCEEEEEEEC
QNGDQLGIKSRQEALEIAGRANLDLVLVAANAKPPVCRIMDYGKYRFEQQKKEKEARKNQ
CCCCCCCCCHHHHHHHHCCCCCCEEEEEECCCCCCEEEEECCCHHHHHHHHHHHHHHHCC
KIINLKEVRLSPGIEEHDFNTKLRNAIKFLQKGDKVKASIRFKGRAITHKEIGQRVLDRF
CEEEHEEEECCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCEECHHHHHHHHHHHH
SEACAEVATVETKPKMDGRSMFLVLAPKTEK
HHHHHHHHHCCCCCCCCCCEEEEEECCCCCC
>Mature Secondary Structure
MQCSQCGCFDARTFCLPVECKETVKMSCEINSKILWRWLIISKDQLVNEGIRAREVRLIG
CCCCCCCCCCCCEEEEECCCHHHEEEEEECCCEEEEEEEEECCHHHHHCCCCEEEEEEEC
QNGDQLGIKSRQEALEIAGRANLDLVLVAANAKPPVCRIMDYGKYRFEQQKKEKEARKNQ
CCCCCCCCCHHHHHHHHCCCCCCEEEEEECCCCCCEEEEECCCHHHHHHHHHHHHHHHCC
KIINLKEVRLSPGIEEHDFNTKLRNAIKFLQKGDKVKASIRFKGRAITHKEIGQRVLDRF
CEEEHEEEECCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCEECHHHHHHHHHHHH
SEACAEVATVETKPKMDGRSMFLVLAPKTEK
HHHHHHHHHCCCCCCCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]