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The map label for this gene is clpX

Identifier: 52786684

GI number: 52786684

Start: 2838580

End: 2839845

Strand: Reverse

Name: clpX

Synonym: BLi02952

Alternate gene names: 52786684

Gene position: 2839845-2838580 (Counterclockwise)

Preceding gene: 52786685

Following gene: 52786683

Centisome position: 67.25

GC content: 47.08

Gene sequence:

>1266_bases
ATGTTTAAATTCAACGAGGAAAAAGGACAATTGAAATGCTCGTTTTGCGGTAAAACACAAGATCAGGTACGCAAGCTTGT
CGCCGGACCAGGCGTATATATATGTGACGAGTGCATCGAACTTTGCACTGAAATTGTAGAAGAGGAACTCGGCTCTGAAG
AAGAAGTGGAGTTCAAAGATGTTCCGAAGCCAAAGGAAATCCGCGAGATTCTTGATGAATACGTCATCGGCCAGGACCAG
GCAAAAAAATCCCTTGCCGTGGCCGTCTACAATCATTACAAGCGGATCAATTCGAACAGCAAAGTCGACGACGTCGAGCT
GTCAAAAAGTAACATTTCCATGATCGGACCGACTGGAAGCGGAAAAACGCTTCTTGCTCAAACGCTTGCCCGCATCCTGA
ATGTGCCGTTCGCCATTGCGGATGCCACGTCGCTTACTGAAGCAGGCTATGTCGGTGAAGATGTGGAGAACATTTTGCTT
AAGCTGATCCAGGCAGCTGACTACGATGTTGAAAAAGCGGAAAAAGGCATTATCTACATCGATGAAATCGATAAAGTGGC
CAGAAAGTCCGAGAACCCTTCGATTACACGCGATGTATCAGGCGAAGGCGTTCAGCAGGCATTGCTTAAAATTCTTGAAG
GTACGGTTGCCAGCGTTCCTCCACAAGGCGGAAGAAAGCATCCTCATCAAGAGTTCATCCAAATTGACACAACCAACATC
CTGTTCATTTGCGGCGGAGCTTTTGACGGAATCGAGCAGATCATCAAGCGCCGTCTCGGCCAGAAGGTCATCGGCTTCGG
CTCTGACAACAAGCATGAAGACCTTGAAAAAGAAGCGCTTCTTTCCAAAGTGCTTCCGGAAGACTTGCTTCGCTTCGGGC
TGATCCCTGAATTCATCGGCCGTCTCCCGATCATCGCAAGCCTTGAGCCGCTGGATGAAAAAGCGCTGGTTGAAATTTTA
ACAAAACCGAAAAACGCGCTTGTTAAACAATATAGAAAAATGCTTGAATTGGATGATGTGGAGCTTGTGTTTGAAGACGA
AGCGCTCACAGAAATCGCTAAAAAAGCAATTGAACGTAAAACAGGAGCACGCGGACTTCGTTCCATTATCGAAGGAATCA
TGCTCGACGTGATGTTTGATCTGCCGTCTCGCGAGGATATTGAAAAATGCGTGATCACAGGCAAAACCGTCACTGACGGC
GAACCGCCGCGTCTCATTATGAAAGACGGCACGGTCGTCAATAAAGACAAAAAAACTTCAGCATAA

Upstream 100 bases:

>100_bases
GAAAGTGTGGTAAAATGCAATACATAATGGAACGAATGTTTTCAAGCGATGTTTCTTTTAACGAAGAAACAGGAATGACA
AGGATATAAGGGGTGAAAGA

Downstream 100 bases:

>100_bases
TGCAGAGAACCTCCTGGCCTAAAGGAGGTTCTTTTTTTGCATCCGGAAACCGTCGGCATCCCGGAGCAGAGTGACGGCTT
CAAAAGCAAAATAATCCCTT

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 421; Mature: 421

Protein sequence:

>421_residues
MFKFNEEKGQLKCSFCGKTQDQVRKLVAGPGVYICDECIELCTEIVEEELGSEEEVEFKDVPKPKEIREILDEYVIGQDQ
AKKSLAVAVYNHYKRINSNSKVDDVELSKSNISMIGPTGSGKTLLAQTLARILNVPFAIADATSLTEAGYVGEDVENILL
KLIQAADYDVEKAEKGIIYIDEIDKVARKSENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPHQEFIQIDTTNI
LFICGGAFDGIEQIIKRRLGQKVIGFGSDNKHEDLEKEALLSKVLPEDLLRFGLIPEFIGRLPIIASLEPLDEKALVEIL
TKPKNALVKQYRKMLELDDVELVFEDEALTEIAKKAIERKTGARGLRSIIEGIMLDVMFDLPSREDIEKCVITGKTVTDG
EPPRLIMKDGTVVNKDKKTSA

Sequences:

>Translated_421_residues
MFKFNEEKGQLKCSFCGKTQDQVRKLVAGPGVYICDECIELCTEIVEEELGSEEEVEFKDVPKPKEIREILDEYVIGQDQ
AKKSLAVAVYNHYKRINSNSKVDDVELSKSNISMIGPTGSGKTLLAQTLARILNVPFAIADATSLTEAGYVGEDVENILL
KLIQAADYDVEKAEKGIIYIDEIDKVARKSENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPHQEFIQIDTTNI
LFICGGAFDGIEQIIKRRLGQKVIGFGSDNKHEDLEKEALLSKVLPEDLLRFGLIPEFIGRLPIIASLEPLDEKALVEIL
TKPKNALVKQYRKMLELDDVELVFEDEALTEIAKKAIERKTGARGLRSIIEGIMLDVMFDLPSREDIEKCVITGKTVTDG
EPPRLIMKDGTVVNKDKKTSA
>Mature_421_residues
MFKFNEEKGQLKCSFCGKTQDQVRKLVAGPGVYICDECIELCTEIVEEELGSEEEVEFKDVPKPKEIREILDEYVIGQDQ
AKKSLAVAVYNHYKRINSNSKVDDVELSKSNISMIGPTGSGKTLLAQTLARILNVPFAIADATSLTEAGYVGEDVENILL
KLIQAADYDVEKAEKGIIYIDEIDKVARKSENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPHQEFIQIDTTNI
LFICGGAFDGIEQIIKRRLGQKVIGFGSDNKHEDLEKEALLSKVLPEDLLRFGLIPEFIGRLPIIASLEPLDEKALVEIL
TKPKNALVKQYRKMLELDDVELVFEDEALTEIAKKAIERKTGARGLRSIIEGIMLDVMFDLPSREDIEKCVITGKTVTDG
EPPRLIMKDGTVVNKDKKTSA

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family

Homologues:

Organism=Homo sapiens, GI7242140, Length=328, Percent_Identity=50, Blast_Score=318, Evalue=7e-87,
Organism=Escherichia coli, GI1786642, Length=401, Percent_Identity=63.5910224438903, Blast_Score=521, Evalue=1e-149,
Organism=Escherichia coli, GI1790366, Length=103, Percent_Identity=46.6019417475728, Blast_Score=99, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI71982908, Length=307, Percent_Identity=46.9055374592834, Blast_Score=280, Evalue=1e-75,
Organism=Caenorhabditis elegans, GI71982905, Length=311, Percent_Identity=46.3022508038585, Blast_Score=279, Evalue=2e-75,
Organism=Caenorhabditis elegans, GI71988663, Length=415, Percent_Identity=38.0722891566265, Blast_Score=253, Evalue=1e-67,
Organism=Caenorhabditis elegans, GI71988660, Length=260, Percent_Identity=39.2307692307692, Blast_Score=177, Evalue=7e-45,
Organism=Saccharomyces cerevisiae, GI6319704, Length=419, Percent_Identity=39.3794749403341, Blast_Score=266, Evalue=3e-72,
Organism=Drosophila melanogaster, GI24648289, Length=320, Percent_Identity=49.375, Blast_Score=304, Evalue=7e-83,
Organism=Drosophila melanogaster, GI24648291, Length=320, Percent_Identity=49.375, Blast_Score=304, Evalue=9e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CLPX_BACLD (Q65GJ4)

Other databases:

- EMBL:   CP000002
- EMBL:   AE017333
- RefSeq:   YP_080096.1
- RefSeq:   YP_092513.1
- HSSP:   O25926
- ProteinModelPortal:   Q65GJ4
- STRING:   Q65GJ4
- EnsemblBacteria:   EBBACT00000055704
- EnsemblBacteria:   EBBACT00000061275
- GeneID:   3029034
- GeneID:   3098420
- GenomeReviews:   AE017333_GR
- GenomeReviews:   CP000002_GR
- KEGG:   bld:BLi02952
- KEGG:   bli:BL00619
- NMPDR:   fig|279010.5.peg.3279
- eggNOG:   COG1219
- GeneTree:   EBGT00050000000359
- HOGENOM:   HBG745965
- OMA:   CGKSQEQ
- ProtClustDB:   PRK05342
- BioCyc:   BLIC279010-1:BLI02952-MONOMER
- BioCyc:   BLIC279010:BL00619-MONOMER
- HAMAP:   MF_00175
- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603
- PANTHER:   PTHR11262:SF4
- SMART:   SM00382
- TIGRFAMs:   TIGR00382

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX

EC number: NA

Molecular weight: Translated: 46685; Mature: 46685

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKFNEEKGQLKCSFCGKTQDQVRKLVAGPGVYICDECIELCTEIVEEELGSEEEVEFKD
CCCCCCCCCCEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
VPKPKEIREILDEYVIGQDQAKKSLAVAVYNHYKRINSNSKVDDVELSKSNISMIGPTGS
CCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCEEECCCCC
GKTLLAQTLARILNVPFAIADATSLTEAGYVGEDVENILLKLIQAADYDVEKAEKGIIYI
CHHHHHHHHHHHHCCCHHHHCCHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHCCCEEEE
DEIDKVARKSENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPHQEFIQIDTTNI
HHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCHHHCCCCCCCCCCCHHHHEEECCCEE
LFICGGAFDGIEQIIKRRLGQKVIGFGSDNKHEDLEKEALLSKVLPEDLLRFGLIPEFIG
EEEECCCHHHHHHHHHHHHCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHC
RLPIIASLEPLDEKALVEILTKPKNALVKQYRKMLELDDVELVFEDEALTEIAKKAIERK
CCCCEECCCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCHHEEECHHHHHHHHHHHHHHH
TGARGLRSIIEGIMLDVMFDLPSREDIEKCVITGKTVTDGEPPRLIMKDGTVVNKDKKTS
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCEEEEECCEEECCCCCCC
A
C
>Mature Secondary Structure
MFKFNEEKGQLKCSFCGKTQDQVRKLVAGPGVYICDECIELCTEIVEEELGSEEEVEFKD
CCCCCCCCCCEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
VPKPKEIREILDEYVIGQDQAKKSLAVAVYNHYKRINSNSKVDDVELSKSNISMIGPTGS
CCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCEEECCCCC
GKTLLAQTLARILNVPFAIADATSLTEAGYVGEDVENILLKLIQAADYDVEKAEKGIIYI
CHHHHHHHHHHHHCCCHHHHCCHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHCCCEEEE
DEIDKVARKSENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPHQEFIQIDTTNI
HHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCHHHCCCCCCCCCCCHHHHEEECCCEE
LFICGGAFDGIEQIIKRRLGQKVIGFGSDNKHEDLEKEALLSKVLPEDLLRFGLIPEFIG
EEEECCCHHHHHHHHHHHHCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHC
RLPIIASLEPLDEKALVEILTKPKNALVKQYRKMLELDDVELVFEDEALTEIAKKAIERK
CCCCEECCCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCHHEEECHHHHHHHHHHHHHHH
TGARGLRSIIEGIMLDVMFDLPSREDIEKCVITGKTVTDGEPPRLIMKDGTVVNKDKKTS
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCEEEEECCEEECCCCCCC
A
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA