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The map label for this gene is mtn

Identifier: 52786589

GI number: 52786589

Start: 2744956

End: 2745651

Strand: Reverse

Name: mtn

Synonym: BLi02855

Alternate gene names: 52786589

Gene position: 2745651-2744956 (Counterclockwise)

Preceding gene: 52786590

Following gene: 52786588

Centisome position: 65.02

GC content: 47.84

Gene sequence:

>696_bases
ATGAAAATCGCAGTTATCGGAGCAATGGAAGAAGAAGTCACGATTTTGCGAAGCAAACTCGAACAGACGAACCGGGAAGT
CATCGCAAACTGTGAATTTACCAGCGGGTTTTATGAAGGAAAAGAGGTCGTGCTTTTAAAGTCCGGCATCGGCAAAGTCA
ATGCAGCCATGAGCACGACGATTCTGCTTGACCGCTTTAAACCGGACGTTGTCATCAACACCGGATCAGCCGGCGGCTTT
CATCATTCGCTTAATGTCGGAGATATCGTCATCTCGACCGAAGTCCGCCATCACGATGTCGATGTCACGGCATTTGATTA
TGAATATGGACAGGTTCCGAATCTGCCGGCTGCATACAAAGCCGACAATGCATTGATCCAAGCGGCGGAAGACGAAGCGT
CTGAACTGGGGCACATTCAGGTTGTCAAAGGAACGATAGCAACAGGCGATTCCTTTATGAGCGATCCTGACCGCGTCGCA
TTCATCCGCGGCAAGTTTGAAGACCTTTACGCGGTTGAAATGGAAGCTGCGGCTGTCGCGCAGGTTTCTTATCAATTTAA
TACGCCGTTTGTTGTCATCAGGGCGCTCTCAGACATCGCCGGAAAAGAATCTGAAATTTCATTTGACCAATTTTTGGAAC
AGGCTGCCAAGCATTCGACAGATCTTGTGCTTCGCATGATTAAAAGAATCAATTAA

Upstream 100 bases:

>100_bases
CTTTACCTCAGAACATTTCAGTATCGCCTTTCAAAAGCATAATGATTTTGTCTGGGTAATGGAAGCGGCAAAATTGTAAT
TTGAAGGGAAGTTTTAAGAT

Downstream 100 bases:

>100_bases
AACAGGGGGGAGGCTCCCCCTCTGTTTTGCACCTCTTGAAGGAGGAAGGAACATGAATGTGATCAAGGATATCACCGAAT
TGATCGGCAAAACGCCGCTT

Product: 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase

Products: NA

Alternate protein names: MTA/SAH nucleosidase; MTAN; 5'-methylthioadenosine nucleosidase; MTA nucleosidase; S-adenosylhomocysteine nucleosidase; AdoHcy nucleosidase; SAH nucleosidase; SRH nucleosidase

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MKIAVIGAMEEEVTILRSKLEQTNREVIANCEFTSGFYEGKEVVLLKSGIGKVNAAMSTTILLDRFKPDVVINTGSAGGF
HHSLNVGDIVISTEVRHHDVDVTAFDYEYGQVPNLPAAYKADNALIQAAEDEASELGHIQVVKGTIATGDSFMSDPDRVA
FIRGKFEDLYAVEMEAAAVAQVSYQFNTPFVVIRALSDIAGKESEISFDQFLEQAAKHSTDLVLRMIKRIN

Sequences:

>Translated_231_residues
MKIAVIGAMEEEVTILRSKLEQTNREVIANCEFTSGFYEGKEVVLLKSGIGKVNAAMSTTILLDRFKPDVVINTGSAGGF
HHSLNVGDIVISTEVRHHDVDVTAFDYEYGQVPNLPAAYKADNALIQAAEDEASELGHIQVVKGTIATGDSFMSDPDRVA
FIRGKFEDLYAVEMEAAAVAQVSYQFNTPFVVIRALSDIAGKESEISFDQFLEQAAKHSTDLVLRMIKRIN
>Mature_231_residues
MKIAVIGAMEEEVTILRSKLEQTNREVIANCEFTSGFYEGKEVVLLKSGIGKVNAAMSTTILLDRFKPDVVINTGSAGGF
HHSLNVGDIVISTEVRHHDVDVTAFDYEYGQVPNLPAAYKADNALIQAAEDEASELGHIQVVKGTIATGDSFMSDPDRVA
FIRGKFEDLYAVEMEAAAVAQVSYQFNTPFVVIRALSDIAGKESEISFDQFLEQAAKHSTDLVLRMIKRIN

Specific function: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively

COG id: COG0775

COG function: function code F; Nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily

Homologues:

Organism=Escherichia coli, GI1786354, Length=230, Percent_Identity=53.4782608695652, Blast_Score=221, Evalue=4e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MTNN_BACLD (Q65GT9)

Other databases:

- EMBL:   CP000002
- EMBL:   AE017333
- RefSeq:   YP_079999.1
- RefSeq:   YP_092418.1
- HSSP:   P0AF12
- ProteinModelPortal:   Q65GT9
- SMR:   Q65GT9
- STRING:   Q65GT9
- EnsemblBacteria:   EBBACT00000058191
- EnsemblBacteria:   EBBACT00000061385
- GeneID:   3028537
- GeneID:   3098114
- GenomeReviews:   AE017333_GR
- GenomeReviews:   CP000002_GR
- KEGG:   bld:BLi02855
- KEGG:   bli:BL02020
- NMPDR:   fig|279010.5.peg.3146
- eggNOG:   COG0775
- GeneTree:   EBGT00050000000478
- HOGENOM:   HBG367723
- OMA:   LEHFPTM
- ProtClustDB:   PRK05584
- BioCyc:   BLIC279010-1:BLI02855-MONOMER
- BioCyc:   BLIC279010:BL02020-MONOMER
- HAMAP:   MF_01684
- InterPro:   IPR010049
- InterPro:   IPR018017
- InterPro:   IPR000845
- PANTHER:   PTHR21234
- TIGRFAMs:   TIGR01704

Pfam domain/function: PF01048 PNP_UDP_1

EC number: =3.2.2.9

Molecular weight: Translated: 25304; Mature: 25304

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: NA

Important sites: ACT_SITE 12-12 BINDING 78-78 BINDING 198-198

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIAVIGAMEEEVTILRSKLEQTNREVIANCEFTSGFYEGKEVVLLKSGIGKVNAAMSTT
CEEEEEECCHHHHHHHHHHHHHCCHHEEEECEECCCCCCCCEEEEEECCCCCHHHHHHHE
ILLDRFKPDVVINTGSAGGFHHSLNVGDIVISTEVRHHDVDVTAFDYEYGQVPNLPAAYK
EEEECCCCCEEEECCCCCCEEEECCCCEEEEEECCEECCCEEEEEECCCCCCCCCCCCCC
ADNALIQAAEDEASELGHIQVVKGTIATGDSFMSDPDRVAFIRGKFEDLYAVEMEAAAVA
CCCCEEEECCHHHHHCCEEEEEEEEEECCCCCCCCCCEEEEEECCCCCEEEEEHHHHEEE
QVSYQFNTPFVVIRALSDIAGKESEISFDQFLEQAAKHSTDLVLRMIKRIN
EEEEECCCCEEEEEEHHHHCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHCC
>Mature Secondary Structure
MKIAVIGAMEEEVTILRSKLEQTNREVIANCEFTSGFYEGKEVVLLKSGIGKVNAAMSTT
CEEEEEECCHHHHHHHHHHHHHCCHHEEEECEECCCCCCCCEEEEEECCCCCHHHHHHHE
ILLDRFKPDVVINTGSAGGFHHSLNVGDIVISTEVRHHDVDVTAFDYEYGQVPNLPAAYK
EEEECCCCCEEEECCCCCCEEEECCCCEEEEEECCEECCCEEEEEECCCCCCCCCCCCCC
ADNALIQAAEDEASELGHIQVVKGTIATGDSFMSDPDRVAFIRGKFEDLYAVEMEAAAVA
CCCCEEEECCHHHHHCCEEEEEEEEEECCCCCCCCCCEEEEEECCCCCEEEEEHHHHEEE
QVSYQFNTPFVVIRALSDIAGKESEISFDQFLEQAAKHSTDLVLRMIKRIN
EEEEECCCCEEEEEEHHHHCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA