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The map label for this gene is yqgN [H]

Identifier: 52786402

GI number: 52786402

Start: 2571783

End: 2572355

Strand: Reverse

Name: yqgN [H]

Synonym: BLi02666

Alternate gene names: 52786402

Gene position: 2572355-2571783 (Counterclockwise)

Preceding gene: 52786403

Following gene: 52786401

Centisome position: 60.92

GC content: 49.39

Gene sequence:

>573_bases
GTGAAGCGTTCTTTACGAAGCGAGGTCAGAAAGAGGCTGGCTAACATGCCGGAACAGGAGTTTCACCTAAAGGCGGAAGC
GATTCACCGGAAGCTTTTCCAATCAAAACAGTGGAAAAAAGCGTCTGTTATTGCCCTTACGGTATCCAGAAATCGCGAAG
TACCGACAAAACCGATTATCGAACAGGCCCGGCTTGAAGGAAAAACGGTGTGCATTCCGAAATGTATGCCTGAAACAAAA
AAGATGCACTTTCGCAGCTATCAGGATGAAAGCGATCTTGAAGTCGTGTATTTTGGCCTGCAGGAACCGATCGTACACAA
AACCGAGCGGATGGAACCCGAAGACATCGACTTCATCCTTGTGCCGGGAATTTGCTATGACCGGAGAGGATACAGAATCG
GCTATGGAGGCGGCTATTATGACAGATACCTGGCCGGCTTTACAAAAGATACCGCGTCGCTTGCCTTCGAGTGCCAAGTG
ATCGGTCATGTTCCAAATGAGCCGCACGACATCCCGGTCAAGCAGGTTTTGACCGAAGACGCCGTTTACAACTGCCTCGA
CACTGCTGAATAA

Upstream 100 bases:

>100_bases
AAGTATTGCCCACGTGACAAAAAATCAACATTACACCGCGAAACAAAGTAAGCAGCAGGGATTTTCCTGCTGTTTTTCTG
TTTTTAAGGGGGAAAGAGAT

Downstream 100 bases:

>100_bases
TTATTAAAAAATGAGACACGATACGGTTATAGGTTATAGGAGGGATCATATGAGAAAAGTTACGTTTATTGTAGTAGGCG
TCATTGCAGCCCTTGTATTT

Product: YqgN

Products: ADP; phosphate; 5,10-methenyltetrahydrofolate

Alternate protein names: NA

Number of amino acids: Translated: 190; Mature: 190

Protein sequence:

>190_residues
MKRSLRSEVRKRLANMPEQEFHLKAEAIHRKLFQSKQWKKASVIALTVSRNREVPTKPIIEQARLEGKTVCIPKCMPETK
KMHFRSYQDESDLEVVYFGLQEPIVHKTERMEPEDIDFILVPGICYDRRGYRIGYGGGYYDRYLAGFTKDTASLAFECQV
IGHVPNEPHDIPVKQVLTEDAVYNCLDTAE

Sequences:

>Translated_190_residues
MKRSLRSEVRKRLANMPEQEFHLKAEAIHRKLFQSKQWKKASVIALTVSRNREVPTKPIIEQARLEGKTVCIPKCMPETK
KMHFRSYQDESDLEVVYFGLQEPIVHKTERMEPEDIDFILVPGICYDRRGYRIGYGGGYYDRYLAGFTKDTASLAFECQV
IGHVPNEPHDIPVKQVLTEDAVYNCLDTAE
>Mature_190_residues
MKRSLRSEVRKRLANMPEQEFHLKAEAIHRKLFQSKQWKKASVIALTVSRNREVPTKPIIEQARLEGKTVCIPKCMPETK
KMHFRSYQDESDLEVVYFGLQEPIVHKTERMEPEDIDFILVPGICYDRRGYRIGYGGGYYDRYLAGFTKDTASLAFECQV
IGHVPNEPHDIPVKQVLTEDAVYNCLDTAE

Specific function: Unknown

COG id: COG0212

COG function: function code H; 5-formyltetrahydrofolate cyclo-ligase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family [H]

Homologues:

Organism=Homo sapiens, GI5453746, Length=191, Percent_Identity=29.3193717277487, Blast_Score=82, Evalue=3e-16,
Organism=Escherichia coli, GI1789278, Length=178, Percent_Identity=28.6516853932584, Blast_Score=82, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17510857, Length=191, Percent_Identity=27.7486910994764, Blast_Score=79, Evalue=1e-15,
Organism=Drosophila melanogaster, GI161077430, Length=194, Percent_Identity=24.7422680412371, Blast_Score=70, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002698 [H]

Pfam domain/function: PF01812 5-FTHF_cyc-lig [H]

EC number: 6.3.3.2

Molecular weight: Translated: 22008; Mature: 22008

Theoretical pI: Translated: 7.90; Mature: 7.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRSLRSEVRKRLANMPEQEFHLKAEAIHRKLFQSKQWKKASVIALTVSRNREVPTKPII
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCHHHH
EQARLEGKTVCIPKCMPETKKMHFRSYQDESDLEVVYFGLQEPIVHKTERMEPEDIDFIL
HHHHCCCCEEEECCCCCHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHCCCCCCCCEEE
VPGICYDRRGYRIGYGGGYYDRYLAGFTKDTASLAFECQVIGHVPNEPHDIPVKQVLTED
ECCEEECCCCCEEECCCCHHHHHHHCCCCCCHHEEEEEEEEECCCCCCCCCCHHHHHHHH
AVYNCLDTAE
HHHHHHHCCC
>Mature Secondary Structure
MKRSLRSEVRKRLANMPEQEFHLKAEAIHRKLFQSKQWKKASVIALTVSRNREVPTKPII
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCHHHH
EQARLEGKTVCIPKCMPETKKMHFRSYQDESDLEVVYFGLQEPIVHKTERMEPEDIDFIL
HHHHCCCCEEEECCCCCHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHCCCCCCCCEEE
VPGICYDRRGYRIGYGGGYYDRYLAGFTKDTASLAFECQVIGHVPNEPHDIPVKQVLTED
ECCEEECCCCCEEECCCCHHHHHHHCCCCCCHHEEEEEEEEECCCCCCCCCCHHHHHHHH
AVYNCLDTAE
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; 5-formyltetrahydrofolate

Specific reaction: ATP + 5-formyltetrahydrofolate = ADP + phosphate + 5,10-methenyltetrahydrofolate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]