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The map label for this gene is fhuD [H]

Identifier: 52786395

GI number: 52786395

Start: 2563902

End: 2564849

Strand: Reverse

Name: fhuD [H]

Synonym: BLi02658

Alternate gene names: 52786395

Gene position: 2564849-2563902 (Counterclockwise)

Preceding gene: 52786396

Following gene: 52786394

Centisome position: 60.74

GC content: 44.09

Gene sequence:

>948_bases
GTGAATATTAAAGGTAAGACGATCGCGGCAGCGTGTTTTGTACTATTATTGATCGCAGCATTGACAGCATGCGGCAATCA
AACAGAGAGCAAAGATTCTTCTTCTAAATCAAAAAGCGAAGAAACGATTACATACAAGGCTGAAAACGGAACGGTTAAAG
TGCCGAAGCATCCGAAGCGGGTGGTTGTCATGGCTGACGATTATTTCGGCTATTTCAAGACACTCGGTCTCAATGTAGTG
GGCGCCCCTGACAGGGTTTTCAAGAATCCTTATTTCAAGGGGAAAACCGATGGTGTGACAAACATAGGTGAAGGAAATTC
TGCTGAAAAGGTTATTCAATTAAAACCGGACTTGATTGTCGTATGGACGACCCAAGGCGCTGATATCGAAAAGCTGGAAA
AAATCGCTCCGACGGTCGCGTTGAAATATGACAGTCTGAATAGCACTGAACGGCTGAAGGATTTCGCAAAAATGACAGGC
ACTGAAGATCAAGCGGAGAAATGGCTGGCTGAATGGGACAAAAAAGTTGCGGCGGCCAAATCAAAAGTTCAAAAAGCTGT
CGGGAACAAAACGGTTTCCATTATGCAAACTAACGGTAAAGAAATCTTTGTATTCGGCGATCAATTCGGAAGGGGAGGAA
GCATTGTTTACCAAGATCTCGGCTTAAAGGCGACAAAGCTGACAAAGGAAAAAGCAATCGACGAAGGCCCGGGCTACACG
AGCATTTCCTTAGAAAAGCTGCCTGATTTCGCTGGAGATTATATATTTATAGGACCTTGGGAATCAAGCGGAGACGACAG
CGCCGTGCTTAATACATCCATTTGGAAGAACCTTGGGGCGGTCAAAAACCAACATGTCTATAAAATCGACCCTGTCGGCT
TCTATTTTTCCGATCCGATTTCATTAGAGGGCCAGCTCGAATTTATTACAGAAAACTTAACAAAATAG

Upstream 100 bases:

>100_bases
GAGGCCGTCATAAAAATCATGATCAAACCGATGCCGGTTATGATATAATTGATAATGATTCTCTTTATCGGGTGATCAAA
CAGGAAAGAAGGTATGAAGA

Downstream 100 bases:

>100_bases
AAGAACTTCCGCCTTGTCAGGCGGAAGTTTTTTTTGCGCGCGAAACCGGGGTGAACCCTCATTGAAAAAGCGATTTTCAA
GTGCAAGCCGGGAGAGTTTT

Product: FhuD

Products: ADP; phosphate; ferric enterobactin [Cytoplasm] [C]

Alternate protein names: Ferric hydroxamate uptake protein D; Ferrichrome-binding protein; Iron(III)-hydroxamate-binding protein fhuD [H]

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MNIKGKTIAAACFVLLLIAALTACGNQTESKDSSSKSKSEETITYKAENGTVKVPKHPKRVVVMADDYFGYFKTLGLNVV
GAPDRVFKNPYFKGKTDGVTNIGEGNSAEKVIQLKPDLIVVWTTQGADIEKLEKIAPTVALKYDSLNSTERLKDFAKMTG
TEDQAEKWLAEWDKKVAAAKSKVQKAVGNKTVSIMQTNGKEIFVFGDQFGRGGSIVYQDLGLKATKLTKEKAIDEGPGYT
SISLEKLPDFAGDYIFIGPWESSGDDSAVLNTSIWKNLGAVKNQHVYKIDPVGFYFSDPISLEGQLEFITENLTK

Sequences:

>Translated_315_residues
MNIKGKTIAAACFVLLLIAALTACGNQTESKDSSSKSKSEETITYKAENGTVKVPKHPKRVVVMADDYFGYFKTLGLNVV
GAPDRVFKNPYFKGKTDGVTNIGEGNSAEKVIQLKPDLIVVWTTQGADIEKLEKIAPTVALKYDSLNSTERLKDFAKMTG
TEDQAEKWLAEWDKKVAAAKSKVQKAVGNKTVSIMQTNGKEIFVFGDQFGRGGSIVYQDLGLKATKLTKEKAIDEGPGYT
SISLEKLPDFAGDYIFIGPWESSGDDSAVLNTSIWKNLGAVKNQHVYKIDPVGFYFSDPISLEGQLEFITENLTK
>Mature_315_residues
MNIKGKTIAAACFVLLLIAALTACGNQTESKDSSSKSKSEETITYKAENGTVKVPKHPKRVVVMADDYFGYFKTLGLNVV
GAPDRVFKNPYFKGKTDGVTNIGEGNSAEKVIQLKPDLIVVWTTQGADIEKLEKIAPTVALKYDSLNSTERLKDFAKMTG
TEDQAEKWLAEWDKKVAAAKSKVQKAVGNKTVSIMQTNGKEIFVFGDQFGRGGSIVYQDLGLKATKLTKEKAIDEGPGYT
SISLEKLPDFAGDYIFIGPWESSGDDSAVLNTSIWKNLGAVKNQHVYKIDPVGFYFSDPISLEGQLEFITENLTK

Specific function: Part of the ABC transporter complex fhuCBGD involved in iron(3+)-hydroxamate import. Binds the iron(3+)-hydroxamate complex and transfers it to the membrane-bound permease. Required for the transport of ferrichrome and coprogen [H]

COG id: COG0614

COG function: function code P; ABC-type Fe3+-hydroxamate transport system, periplasmic component

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Fe/B12 periplasmic-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002491 [H]

Pfam domain/function: PF01497 Peripla_BP_2 [H]

EC number: NA

Molecular weight: Translated: 34475; Mature: 34475

Theoretical pI: Translated: 8.14; Mature: 8.14

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50983 FE_B12_PBP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIKGKTIAAACFVLLLIAALTACGNQTESKDSSSKSKSEETITYKAENGTVKVPKHPKR
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCEEECCCCCCE
VVVMADDYFGYFKTLGLNVVGAPDRVFKNPYFKGKTDGVTNIGEGNSAEKVIQLKPDLIV
EEEEECCHHHHHHHHCCEEECCCHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEECCCEEE
VWTTQGADIEKLEKIAPTVALKYDSLNSTERLKDFAKMTGTEDQAEKWLAEWDKKVAAAK
EEECCCCCHHHHHHHCCEEEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
SKVQKAVGNKTVSIMQTNGKEIFVFGDQFGRGGSIVYQDLGLKATKLTKEKAIDEGPGYT
HHHHHHHCCCEEEEEEECCCEEEEECCCCCCCCCEEEECCCCCHHHHHHHHCCCCCCCCC
SISLEKLPDFAGDYIFIGPWESSGDDSAVLNTSIWKNLGAVKNQHVYKIDPVGFYFSDPI
EEEHHHCCCCCCCEEEEECCCCCCCCCEEEEHHHHHHHCCCCCCCEEEECCCCEEECCCC
SLEGQLEFITENLTK
CCCCHHHEEHHHCCC
>Mature Secondary Structure
MNIKGKTIAAACFVLLLIAALTACGNQTESKDSSSKSKSEETITYKAENGTVKVPKHPKR
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCEEECCCCCCE
VVVMADDYFGYFKTLGLNVVGAPDRVFKNPYFKGKTDGVTNIGEGNSAEKVIQLKPDLIV
EEEEECCHHHHHHHHCCEEECCCHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEECCCEEE
VWTTQGADIEKLEKIAPTVALKYDSLNSTERLKDFAKMTGTEDQAEKWLAEWDKKVAAAK
EEECCCCCHHHHHHHCCEEEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
SKVQKAVGNKTVSIMQTNGKEIFVFGDQFGRGGSIVYQDLGLKATKLTKEKAIDEGPGYT
HHHHHHHCCCEEEEEEECCCEEEEECCCCCCCCCEEEECCCCCHHHHHHHHCCCCCCCCC
SISLEKLPDFAGDYIFIGPWESSGDDSAVLNTSIWKNLGAVKNQHVYKIDPVGFYFSDPI
EEEHHHCCCCCCCEEEEECCCCCCCCCEEEEHHHHHHHCCCCCCCEEEECCCCEEECCCC
SLEGQLEFITENLTK
CCCCHHHEEHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; ferric enterobactin [Periplasm]; H2O [C]

Specific reaction: ATP + ferric enterobactin [Periplasm] + H2O = ADP + phosphate + ferric enterobactin [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8388528; 9639930; 9384377 [H]