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The map label for this gene is yqhS

Identifier: 52786356

GI number: 52786356

Start: 2533819

End: 2534256

Strand: Reverse

Name: yqhS

Synonym: BLi02618

Alternate gene names: 52786356

Gene position: 2534256-2533819 (Counterclockwise)

Preceding gene: 52786357

Following gene: 52786355

Centisome position: 60.02

GC content: 46.8

Gene sequence:

>438_bases
TTGCCGCATATTTTAATTTTGAACGGACCGAATTTAAACCGGCTTGGAAAACGCGAACCCGATGTATACGGGACAGACAC
ATTAACCGATTTGGAACAAAGACTTTTTCAATTTGCCGAAGGCATTCAGACAGAATTGACTTTTTTTCAGTCAAACCACG
AAGGGGACCTGATTGATGCTCTTCATGAGGCAGAGGAGCAATACGATGGAATCGTCTTGAATCCGGGGGCTTTCTCGCAT
TACAGCTATGCCCTCCGCGATGCGGTGGCTGCAATCAGCATACCGGTGATTGAGGTTCATCTTTCAAATCCTCATGCAAG
GGAAGAGTTCCGGCACCGCTCGGTCATCGCTCCGGTTGCAAGAGGCCAGATCACCGGACTCGGCTTTGAAGGTTATAAGC
TGGCCATCTCTTATTTTATGAACACAAATAACAAATAG

Upstream 100 bases:

>100_bases
CTTGGAGAAACAAGAGAATAGTGCCTGATCAGGAAGCAATATGATAAAATGTTCACTGTAAGTGGACATTTTTTTGCGTG
ATGAGAAGGGGGAGGCAGAG

Downstream 100 bases:

>100_bases
GGGGACTAGTGGACAATGAAACTAAACAAATTGAGAGAGCTTTTCGGCGGTTTAGGCATTGACGGTATATTGGTGACGAG
CGGCGTTAATTTGCGGTACA

Product: 3-dehydroquinate dehydratase

Products: NA

Alternate protein names: 3-dehydroquinase; Type II DHQase

Number of amino acids: Translated: 145; Mature: 144

Protein sequence:

>145_residues
MPHILILNGPNLNRLGKREPDVYGTDTLTDLEQRLFQFAEGIQTELTFFQSNHEGDLIDALHEAEEQYDGIVLNPGAFSH
YSYALRDAVAAISIPVIEVHLSNPHAREEFRHRSVIAPVARGQITGLGFEGYKLAISYFMNTNNK

Sequences:

>Translated_145_residues
MPHILILNGPNLNRLGKREPDVYGTDTLTDLEQRLFQFAEGIQTELTFFQSNHEGDLIDALHEAEEQYDGIVLNPGAFSH
YSYALRDAVAAISIPVIEVHLSNPHAREEFRHRSVIAPVARGQITGLGFEGYKLAISYFMNTNNK
>Mature_144_residues
PHILILNGPNLNRLGKREPDVYGTDTLTDLEQRLFQFAEGIQTELTFFQSNHEGDLIDALHEAEEQYDGIVLNPGAFSHY
SYALRDAVAAISIPVIEVHLSNPHAREEFRHRSVIAPVARGQITGLGFEGYKLAISYFMNTNNK

Specific function: Catalyzes a trans-dehydration via an enolate intermediate

COG id: COG0757

COG function: function code E; 3-dehydroquinate dehydratase II

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-II 3-dehydroquinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROQ_BACLD (Q65HH2)

Other databases:

- EMBL:   CP000002
- EMBL:   AE017333
- RefSeq:   YP_079771.1
- RefSeq:   YP_092185.1
- HSSP:   P54517
- ProteinModelPortal:   Q65HH2
- SMR:   Q65HH2
- STRING:   Q65HH2
- EnsemblBacteria:   EBBACT00000054361
- EnsemblBacteria:   EBBACT00000062195
- GeneID:   3029499
- GeneID:   3097411
- GenomeReviews:   AE017333_GR
- GenomeReviews:   CP000002_GR
- KEGG:   bld:BLi02618
- KEGG:   bli:BL01544
- NMPDR:   fig|279010.5.peg.463
- eggNOG:   COG0757
- GeneTree:   EBGT00050000003572
- HOGENOM:   HBG284657
- OMA:   IMVINGP
- ProtClustDB:   PRK05395
- BioCyc:   BLIC279010-1:BLI02618-MONOMER
- BioCyc:   BLIC279010:BL01544-MONOMER
- HAMAP:   MF_00169
- InterPro:   IPR001874
- InterPro:   IPR018509
- Gene3D:   G3DSA:3.40.50.9100
- PANTHER:   PTHR21272
- PIRSF:   PIRSF001399
- ProDom:   PD004527
- TIGRFAMs:   TIGR01088

Pfam domain/function: PF01220 DHquinase_II; SSF52304 DHquinase_II

EC number: =4.2.1.10

Molecular weight: Translated: 16296; Mature: 16164

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: PS01029 DEHYDROQUINASE_II

Important sites: ACT_SITE 23-23 ACT_SITE 100-100 BINDING 74-74 BINDING 80-80 BINDING 87-87 BINDING 111-111

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHILILNGPNLNRLGKREPDVYGTDTLTDLEQRLFQFAEGIQTELTFFQSNHEGDLIDA
CCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCHHHHHHEEECCCCCHHHHH
LHEAEEQYDGIVLNPGAFSHYSYALRDAVAAISIPVIEVHLSNPHAREEFRHRSVIAPVA
HHHHHHHHCCEEECCCCCCHHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHCCCC
RGQITGLGFEGYKLAISYFMNTNNK
CCEEEECCCCCHHEEEEEEECCCCC
>Mature Secondary Structure 
PHILILNGPNLNRLGKREPDVYGTDTLTDLEQRLFQFAEGIQTELTFFQSNHEGDLIDA
CEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCHHHHHHEEECCCCCHHHHH
LHEAEEQYDGIVLNPGAFSHYSYALRDAVAAISIPVIEVHLSNPHAREEFRHRSVIAPVA
HHHHHHHHCCEEECCCCCCHHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHCCCC
RGQITGLGFEGYKLAISYFMNTNNK
CCEEEECCCCCHHEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA